• Title/Summary/Keyword: iap

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Distribution of Epiphytic Lichens around Thermoelectric Power Plant (화력발전소 주변의 착생지의류 분포)

  • 김종갑;이총규;이정환;박은희;오기철
    • The Korean Journal of Ecology
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    • v.27 no.3
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    • pp.121-126
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    • 2004
  • The purpose of this study was to investigate the distribution of epiphytic lichens that growing near the thermoelectric power plant to obtain a basic data for air environmental evaluation around the power plant. The study areas were all 12 places including ten sites near the power plant and two sites for control. All the number of lichens appeared in this study areas were 27 species. It showed to 4∼6 species within 4㎞ from the power plant, and coverage also was low. As receding from the power plant, both the number of species and overage increased. Parmelia tinctorum sensitive to air pollution did not appear within 4㎞ from the power plant, and it was regarded as the sensitive kind to air pollution. Lepraria sp.(13.40%), Parmelia austrosinensis (13.40%), and Dirinaria applanaita (13.40%) were distributed in all sites, and it could infer that they had tolerance to air pollution. The IAP (Index of Atmosphere Purity) values in Sadungdong Apsan, Seksangeabal and the Power plant were four times as low as those in Mt, Yeonwha, and it could infer that the air in those areas was not good. It was high IAP values as being distant from the power plant.

Abdominal Hypertension after Abdominal Plication in Postbariatric Patients: The Consequence in the Postoperative Recovery

  • Martin Morales-Olivera;Erik Hanson-Viana;Armando Rodriguez-Segura;Marco A. Rendon-Medina
    • Archives of Plastic Surgery
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    • v.50 no.6
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    • pp.535-540
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    • 2023
  • Background Abdominoplasty with abdominal plication increases intra-abdominal pressure (IAP) and has been previously associated with limited diaphragmatic excursion and respiratory dysfunctions. Many factors found in abdominoplasties and among postbariatric patients predispose them to a higher occurrence. This study aims to evaluate the impact of abdominal plication among postbariatric patients, assess whether the plication increases their IAP, and analyze how these IAP correlate to their postoperative outcome. Methods This prospective study was performed on all patients who underwent circumferential Fleur-De-Lis abdominoplasty. For this intended study, the IAP was measured by an intravesical minimally invasive approach in three stages: after the initiation of general anesthesia, after a 10-cm abdominal wall plication and skin closure, and 24 hours after the procedure. Results We included 46 patients, of which 41 were female and 5 were male. Before the bariatric procedure, these patients had an average maximum weight of 121.4 kg and an average maximum body mass index of 45.78 kg/m2; 7 were grade I obese patients, 10 were grade II, and 29 were grade III. Only three patients were operated on with a gastric sleeve and 43 with gastric bypass. We presented six patients with transitory intra-abdominal hypertension in the first 24 hours, all of them from the grade I obesity group, the highest presented was 14.3 mm Hg. We presented 15% (7/46) of complication rates, which were only four seroma and five dehiscence; two patients presented both seroma and wound dehiscence. Conclusion Performing a 10-cm abdominal wall plication or greater represents a higher risk for intra-abdominal hypertension, slower general recovery, and possibly higher complication rate in patients who presented a lower degree of obesity (grade I) at the moment of the bariatric surgery.

A Secure Communication Framework for the Detection System of Network Vulnerability Scan Attacks (네트워크 취약점 검색공격 탐지 시스템을 위한 안전한 통신 프레임워크 설계)

  • You, Il-Sun;Kim, Jong-Eun;Cho, Kyung-San
    • The KIPS Transactions:PartC
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    • v.10C no.1
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    • pp.1-10
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    • 2003
  • In this paper, we propose a secure communication framework for interaction and information sharing between a server and agents in DS-NVSA(Detection System of Network Vulnerability Scan Attacks) proposed in〔1〕. For the scalability and interoperability with other detection systems, we design the proposed IDMEF and IAP that have been drafted by IDWG. We adapt IDMEF and IAP to the proposed framework and provide SKTLS(Symmetric Key based Transport Layer Security Protocol) for the network environment that cannot afford to support public-key infrastructure. Our framework provides the reusability of heterogeneous intrusion detection systems and enables the scope of intrusion detection to be extended. Also it can be used as a framework for ESM(Enterprise Security Management) system.

Structural and Functional Roles of AIMP2 and TRAF2 in TNF-α Signaling (TNF-α 신호에서 AIMP2와 TRAF2의 구조적 및 기능적 역할)

  • Kim, Hyeon Jin;Jeong, Mi Suk;Jang, Se Bok
    • Journal of Life Science
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    • v.30 no.1
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    • pp.106-112
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    • 2020
  • Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 (AIMP2) is a scaffolding protein required for the assembly of multi-tRNA synthetase, and it can exert pro-apoptotic activity in response to DNA damage. In the presence of DNA damage, AIMP2 binds to mouse double minute 2 homolog (MDM2) to protect p53 from MDM2 attack. TGF-β signaling results in the nuclear translocation of AIMP2, whereby AIMP2 interacts with FUSE-binding protein, and, thus, suppresses c-myc. TNF receptor-associated factor 2 (TRAF2) is an important mediator between TNF-receptors 1 and 2 which are involved in the signaling of c-Jun N-terminal kinase (JNK), nuclear factor κB (NF-κB), and p38 mitogen-activated protein kinases (MAPKs). TRAF2 is required for the activations of JNK and NF-κB via TNF-α and the mediation of anti-apoptosis signaling. AIMP2 can also enhance pro-apoptosis in the TNF-α signaling. During this signaling, AIMP2 assists the association of E3 ubiquitin ligase, the cellular inhibitor of apoptosis protein 1 (c-IAP1) which is well known and responsible for the degradation of TRAF2. The formation of a complex among AIMP2, TRAF2, and c-IAP1 results in proteasome-mediated TRAF2 degradation. AIMP2 can induce apoptosis via downregulation of TRAF2 to interact directly in TNF-α signaling. This review provides new insight into the molecular mechanism responsible for AIMP2 and TRAF2 complex formation and treatments for TNFα-associated diseases.

Induction of Apoptosis by Water Extract of Glycyrrhizae radix in Human Bladder T24 Cancer Cells (인체 방광암 T24 세포에서 감초(Glycyrrhizae radix) 열수추출물에 의한 apoptosis 유도)

  • Lee, Ki Won;Kim, Jeong Il;Lee, Seung Young;Choi, Kyung-Min;Oh, Young Taek;Jeong, Jin-Woo
    • Korean Journal of Plant Resources
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    • v.32 no.4
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    • pp.255-263
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    • 2019
  • Glycyrrhizae radix is one of the most frequently prescribed ingredients in Oriental medicine, and Glycyrrhizae radix extract has been shown to exert anti-cancer effects. However, the cellular and molecular mechanisms of programed cell death (apoptosis) by Glycyrrhizae radix are poorly defined. In the present study, it was examined the molecular mechanisms of apoptosis by water extracts of Glycyrrhizae radix (GRW) in human bladder T24 cancer cells. It was found that GRW could inhibit the cell growth of T24 cells in a concentration-dependent manner, which was associated with the induction of apoptotic cell death, as evidenced by the formation of apoptotic bodies, DNA fragmentation and increased populations of annexin-V positive cells. The induction of apoptotic cell death by GRW was connected with an up-regulation of pro-apoptotic Bax protein expression and down-regulation of anti-apoptotic proteins (Bcl-2 and Bcl-xL), and inhibition of apoptosis family proteins (XIAP, cIAP-1 and cIAP-2). In addition, apoptosis-inducing concentrations of GRW induced the activation of caspase-9, an initiator caspase of the mitochondrial-mediated intrinsic pathway, and caspase-3, accompanied by proteolytic degradation of PARP. GRW also induced apoptosis via a death receptor-mediated extrinsic pathway by caspase-8 activation, resulting in the down-regulation of total Bid and suggesting the existence of cross-talk between the extrinsic and intrinsic pathways. Taken together, the present results suggest that GRW may be a potential chemotherapeutic agent for the control of human bladder cancer cells.

Anti-apoptosis Engineering

  • Kim, Eun-Jeong;Park, Tai-Hyun
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.8 no.2
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    • pp.76-82
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    • 2003
  • An increased understanding of apoptosis makes anti-apoptosis engineering possible, which is an approach used to inhibit apoptosis for the purpose of therapeutic, or industrial applications in the treatment of the diseases associated with increased apoptosis, or to improve the productivity of animal cell cultures, respectively. Some known anti-apoptosis proteins are the Bcl-2 family, IAP (inhibitor of apoptosis) and Hsps (heat shock proteins), with which anti-apoptosis engineering has progressed. This article reviews anti-apoptosis engineering using known anti-apoptosis compounds, and introduces a 30 K protein, isolated from silkworm hemolymph, as a novel anti-apoptotic protein, that Shows no homology with other known anti-apoptotic proteins. The regulation of apoptosis, using anti-apoptotic proteins and genes originating from the silkworm, Bombyx mori, may provide a new strategy in this field.

Implementing an Intrusion Detection Message Exchange Library for Realtime Interaction between SDMS-RTIR and Heterogeneous Systems (이기종의 침입탐지 시스템과 SDMS-RTIR의 실시간 상호연동을 지원하는 침입탐지 메시지 교환 라이브러리 구현)

  • Yun, Il-Sun;Lee, Dong-Ryun;Oh, Eun-Sook
    • The KIPS Transactions:PartC
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    • v.10C no.5
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    • pp.565-574
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    • 2003
  • This paper implements an intrusion detection message exchange protocol library (IDMEPL) for SDMS-RTIR, which Korea Information Security Agency (KISA) has developed to hierarchically detect and respond to network vulnerability scan attacks. The IDMEPL, based on the IDMEF and the IAP of the IDWG, enables SDMS-RTIR to interact with other intrusion detection systems (IDS) in realtime, and supports the TLS protocol to prevent security threats in exchanging messages between its server and its agents. Especially, with the protocol selection stage, the IDMEPL can support various protocols such as the IDXP besides the IAP. Furthermore, it can allow for agents to choose an appropriate security protocol for their own network, achieving security stronger than mutual authentication. With the IDMEPL, SDMS-RTIR can receive massive intrusion detection messages from heterogeneous IDSes in large-scale networks and analyze them.

Antioxidative Activities and Quality Characteristics of Gruel as a Home Meal Replacement with Angelica keiskei Powder Pre-treated by Various Drying Methods (전처리 건조 방법에 따른 간편가정식용 신선초죽의 항산화 효과와 품질 특성)

  • Kim, Hae Young;Choi, Su-Jin;Ra, Ha-Na;Lee, Jong-Eun
    • Journal of the Korean Society of Food Culture
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    • v.29 no.1
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    • pp.91-100
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    • 2014
  • This study investigated the antioxidative activities and quality characteristics of gruel as a home meal replacement with Angelica keiskei powder pre-treated by far-infrared radiation or freeze-drying methods. Far-infrared treated Angelica keiskei powder (F-IAP) showed significantly lighter, weaker green, and stronger yellow color values than powder subjected to freezedrying (FAP) (p<0.001). F-IAP showed higher total phenolic compound contents than that of the FAP. ABTS radical scavenging activity of F-IAP was 50.31%, which was significantly higher than that of FAP, at 43.51% (p<0.05). Color values of gruel significantly decreased with increased addition of Angelica keiskei powder (p<0.05). Gruels containing far-infrared treated Angelica keiskei powder (F-IAG) showed higher total phenolic compound contents as well as ABTS radical scavenging activities compared to the gruels containing freeze-dried Angelica keiskei powder (FAG). Gruels containing 5 g of Angelica keiskei powder showed 2.0 to 2.5 times higher antioxidant activities than those containing powder alone due to the presence of other ingredients with antioxidant activities such as black soybean or sweet pumpkin. In the results of sensory evaluation, F-IAG containing more than 5 g of Angelica keiskei powder had higher sweetness and roasted grain flavor, as well as lower bitterness and astringency compared to FAG. Sensory acceptance tests of all samples showed higher scores than 5.0 representing possibilities of successful development of gruels as a home meal replacement containing Angelica keiskei powder.