• Child Health Nursing Research
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• v.20 no.3
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• pp.205-214
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• 2014

Purpose: The purpose of the study was to develop and evaluate the effect of a metabolic syndrome prevention program using mobile application for university students. Methods: A pretest-posttest design with content analysis as a triangulation method was used. The participants were 49 university students. Data were analyzed using descriptive statistics, $x^2$-test, t-test and Fisher's exact test with the SPSS WIN 18.0 program. Results: The application consisted of six main menus as follows: 'basic education', 'nutrition education', 'exercise education', 'meal diary', 'exercise checkup', and 'tips'. The experimental group had higher recognition about metabolic syndrome prevention than the control group (F=7.919, p=.007). Understanding of metabolic syndrome among participants was mostly related to chronic diseases such as obesity, hypertension and diabetes in relation to the importance of eating habits and exercising. Conclusion: The results indicate that metabolic syndrome prevention education using mobile application is necessary and would be useful for university students.

• Journal of the Korea Convergence Society
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• v.1 no.1
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• pp.83-91
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• 2010

In accordance with the analysis results on the questionnaires, in the awareness of employees on a public health center, the answer "I can make every endeavor for the success of public health center organization" showed the highest score as $4.07{\pm}0.75$. The awareness on the organization where a subject was included was higher than the average out of a 7 points. It showed the subjects were sincere to the missions and duties of the organizations where they were included. For the awareness on the work environment, the subjects who considered that their workplace was comfortable were higher than the average. The duties which the subjects recognized as the necessary duties among health businesses include health behavior improvement project, disease control project, customized visiting health care project, maternal and child health care, family health care and infectious disease control project. The duties which were considered as unnecessary among health care projects were general care functions, administrative businesses including issuance of certificates and various kinds of civil application processing. The projects which were considered to be reinforced or implemented in the future were health care project for the old, patients registration and care project including hypertension and diabetes and health promotion project in that order.

• Journal of dental hygiene science
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• v.17 no.4
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• pp.298-305
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• 2017

This study aimed to investigate the relationship between sleep duration and periodontitis in adult Korean women. This cross-sectional study was based on the 2014 Korea National Health and Nutrition Examination Survey (KNHNES). We selected the data from 3,292 women (over 19 years of age) out of 7,550 participants for analysis, after excluding data from men. Complex logistic regression analysis was performed to determine the effect of sleep duration on the risk of periodontitis; the crude and adjusted odds ratios (ORs) were calculated. The risk of periodontitis was higher in participants who had a sleep duration of 7 hours or more, than in those with less than 7 hours (crude OR) by 1.37 times (95% confidence interval [CI], 1.13~1.65). The adjusted OR of the participants after adjusting for the sample characteristics of the participants (age, education level, income level, diabetes, hypertension, obesity) was 1.04 times (95% CI, 0.82~1.32), but the risk for periodontitis was slightly higher, though not statistically significant. This study confirmed the relationship between sleep duration and the risk of periodontitis in Korean women. Therefore, it is necessary to develop and implement a comprehensive health promotion program that can improve the proper sleeping habits of adult women in Korea and to combine oral hygiene management programs to prevent periodontal disease.

• Journal of Life Science
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• v.29 no.4
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• pp.447-454
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• 2019

Fat accumulation in adipocytes occurs through the process of adipogenesis in which preadipocytes differentiate into adipocytes. Obesity is a metabolic disorder caused by excessive accumulation of fat in the body, which increases the incidence of cardiovascular diseases, hypertension, type 2 diabetes, hyperlipidemia, and various cancers. Recently, inhibition of adipocyte differentiation was shown to be a potential antiobesity strategy. In this study, the inhibitory effect of dichloromethane fractions from Illicium verum Hooker fil. water extract on the differentiation of 3T3-L1 preadipocytes to adipocytes was investigated. Dichloromethane fractions from I. verum Hooker fil. significantly inhibited adipocyte differentiation when applied during the adipocyte differentiation process, as assessed by measuring fat accumulation using Oil-red O staining. In addition, dichloromethane fractions from I. verum Hooker fil. reduced important adipogenic transcription factors, such as CCAAT/enhancer binding protein ${\alpha}$ ($C/EBP{\alpha}$), $C/EBP{\beta}$, and peroxisome proliferator activated receptor ${\gamma}$ ($PPAR{\gamma}$). The expression of FAS and LPL, which are terminal differentiation markers of mature adipocytes, was also reduced in the 3T3-L1 adipocytes treated with dichloromethane fractions from I. verum Hooker fil. In addition, the treatment significantly inhibited mitotic clonal expansion, which is essential for adipocyte differentiation, by arresting the G1 phase of the cell cycle. Taken together, these results suggest that dichloromethane fractions from I. verum Hooker fil. may be a natural material with antiobesity effects.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.826-835
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• 2020

The purpose of this study was to examine the mediating effect of stress on the relationship between oral health behaviors and health-related quality of life (HRQOL) in the elderly. We analyzed 8148 subjects aged 65 or older who participated in the Korea National Health and Nutrition Examination Survey (2010-2015). All individuals were asked about their socioeconomic history, general health, and oral health behaviors (the frequency of tooth brushing, regular dental check-ups, and use of interdental cleaners). In the results, HRQOL was low in the elderly from a low socioeconomic class, or with diabetes mellitus, hypertension, or poor oral health behaviors. A partial mediating effect from stress was confirmed on the relationship between oral health behaviors and HRQOL. In conclusion, HRQOL was associated with oral health behaviors, with a mediating effect from stress. Therefore, it is necessary that a convergence health promotion program should be planned with an oral health education program and a stress management program for the elderly.

• The Journal of the Society of Stroke on Korean Medicine
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• v.9 no.1
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• pp.19-24
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• 2008

Objectives : This study was conducted as part of the national project to standardize stroke diagnosis in Korean medicine. In this study, we assessed what categories of stroke diagnosis these three most common risk factors of cerebro-vascular attack(CVA), hypertension(HTN), diabetes mellitus(DM) and hyperlipidemia(HL) fall into. Also we looked into stroke subtypes and its diagnosis in Korean medicine. Methods : 806 patients with acute stroke from 5 universities(Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo Medical Center, Kyungwon university Incheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university Ilsan oriental medical center) across the country were involved from April, 2007 til August, 2008. We had data of 482 patients to be analyzed and diagnosed by a Korean medicine training doctor and a professor. Results : All three major stroke risk factors were diagnosed as being dampness-phlegm pattern, but no significant difference was observed except in hyperlipidemia patients. Stroke subtypes such as hemorrhage and infarction showed no significant difference in this study. Conclusions : This study provides evidence that hyperlipidemia can be diagnosed as dampness-phlegm by Korean medicine. Further studies with various subtypes of stroke patients are required to prove solid evidence with other stroke risk factors.

• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.735-742
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• 2023

Non-alcoholic fatty liver disease is an independent risk factor for the development of cardiovascular disease, diabetes, hypertension, and kidney disease, and the clinical importance of non-alcoholic fatty liver disease has recently been increasing. In this study, we aim to extract feature values by applying GLCM, a texture analysis method, to ultrasound images of patients with non-alcoholic fatty liver disease. By applying an artificial neural network model using extracted feature values, we would like to classify the degree of fat deposition in non-alcoholic fatty liver into normal liver, mild fatty liver, moderate fatty liver, and severe fatty liver. As a result of applying the GLCM algorithm, the parameters Autocorrelation, Sum of squares, Sum average, and sum variance showed a tendency for the average value of the feature values to increase as it progressed from mild fatty liver to moderate fatty liver to severe fatty liver. The four parameters of Autocorrelation, Sum of squares, Sum average, and sum variance extracted by applying the GLCM algorithm to ultrasound images of non-alcoholic fatty liver disease were applied as inputs to the artificial neural network model. The classification accuracy was evaluated by applying the GLCM algorithm to the ultrasound images of non-alcoholic fatty liver disease and applying the extracted images to an artificial neural network, showing a high accuracy of 92.5%. Through these results, we would like to present the results of this study as basic data when conducting a texture analysis GLCM study on ultrasound images of patients with non-alcoholic fatty liver disease.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.365-374
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• 2018

This study investigated the relationship between Vitamin D levels and indices related to cardiovascular disease in Korean adults aged ${\geq}19years$. The data for analysis were obtained from the sixth Korea National Health Nutrition Examination Survey in 2013 and 2014. The results showed that the incidence of Vitamin D deficiency was 73.1% among Korean adults and that indices related to cardiovascular disease showed an increasing trend (55.6% of Korean adults). The relationship between Vitamin D levels and indices related to cardiovascular disease with controlled physical activity status was also studied. The odds ratios (ORs) for age were 1.72 for the 4-62 years age group (95% CI, 1.53-1.93) and 2.05 for the ${\geq}65years$ age group (95% CI, 1.71-2.45). For blood pressure, the OR for pre-hypertension was 1.30 (95% CI, 1.15-1.47) and that for hypertension was 1.31 (95% CI, 1.11-1.54). For body mass index (BMI), the OR was 1.36 (95% CI, 1.11-1.66) and that for waist circumference (WC) was 1.36 (95% CI, 1.11-1.66). For fasting blood sugar (FBS), the OR for impaired fasting glucose (IFG) was 1.37 (95% CI, 1.21-1.55) and that for diabetes mellitus (DM) was 1.31 (95% CI, 1.05-1.65). The OR for total cholesterol (TC) was 1.30 (95% CI, 1.11-1.52) and that for triglycerides (TG) was 1.20 (95% CI, 1.04-1.37) in Korean adults. There was a significant relationship between Vitamin D and indices related to cardiovascular disease in Korean adults with respect to age, blood pressure, FBS, BMI, TC and TG. Confirmation of a causal relationship between Vitamin D and indices related to cardiovascular disease may require further research consisting of more systematic cohort studies.

• The Korean Journal of Applied Statistics
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• v.22 no.2
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• pp.329-340
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• 2009

For complex diseases such as diabetes, hypertension, it is believed that model-free methods might work better because they do not require a precise knowledge of the mode of inheritance controlling the disease trait. This is done by estimating the sharing probabilities that a pair shares zero, one, or two alleles identical by descent(IBD) and has some specific branches of test procedure, i.e., the mean test, the proportion test, and the minmax test. Among them, the minmax test is known to be more robust than others regardless of genetic mode of inheritance in current use. In this study, we compared the power of the methods which are based on minmax test and considering weighting schemes for sib-pairs to analyze sibship data. In simulation result, we found that the method based on Suarez' was more powerful than any others without respect to marker allele frequency, genetic mode of inheritance, sibship size. Also, The power of both Suarez- and Hodge-based methods was higher when marker allele frequency and sibship size were higher, and this result was remarkable in dominant mode of inheritance especially.

• Journal of Digital Convergence
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• v.19 no.7
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• pp.253-261
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• 2021

This study aims to confirm the association with the willingness to quit smoking in adult smokers with chronic diseases, and the research method was analyzed using data from the 7th National Health and Nutrition Survey (2016-2018). The subjects were frequency analysis, chi-square test, and logistic regression analysis of 960 chronically ill patients aged 19 years or older, which were analyzed using the SPSS 26.0 Program. As a result of the study, depending on the level of education, high school graduation (OR=1.328, 95%CI=1.004-1.757), college graduation or higher (OR=1.556, 95%CI=1.167-2.075), the more stressed you are (OR=1.602, 95%CI) =1.217-2.109), there was an attempt to quit smoking (OR=5.263, 95% CI=4.287-6.462), which was associated with the willingness to quit smoking. It is necessary to prevent chronic diseases by reducing the smoking rate through active participation in smoking cessation programs targeting groups with high willingness to quit smoking, and by preparing measures to relieve appropriate stress.