• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.102-110
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• 2010

This study was designed to investigate the hyperlipidemia-healing effect of aqueous extract from Mahwangimun-tang(麻黃二門湯) and it was performed on the hyperlipidemia of rats induced by high cholesterol diet and Triton WR-1339. We prepared two types of hyperlipidemia model in rats induced by high cholesterol diet and Triton WR-1339. The amount of total cholesterol, HDL-cholesterol, LDL -cholesterol, triglyceride, phospholipid, free fatty acid, the activity of superoxide dismutase and glutathione were measured. The aqueous extract from Mahwangimun-tang showed significant decreasing effects on total cholesterol, LDL- cholesterol, triglyceride in the both model. And it showed significant increasing effects on HDL-cholesterol, the activity of SOD in both model. These results suggest that aqueous extract from Mahwangimun-tang has healing efficacy on hyperlipidemia induced by high cholesterol diet and Triton WR-1339.

• Journal of Society of Preventive Korean Medicine
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• v.6 no.2
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• pp.128-136
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• 2002

In order to study effects of ${\ulcorner}Persicae\;Semen{\lrcorner}$ on the hyperlipidemia rats induced by Triton WR, we have made hyperlipidemia rats by administering Triton WR-1339 for 3 days, then have administered. The results were summerized as follows: 1. The total cholesterol, triglyceride and phospholipid by hypercholesteremic rats injected by Triton WR-1339 of the sample group were decreased as compared with those of the control group, 2. The HDL-cholesterol by hypercholesteremic rats injected by Trion WR -1339 were increased as compeared those of control group. According to the above results, Persicae Semen showed inhibition on increase of serum total cholesterol, triglyceride and phosholipid contents as well as inhibition on decrease of HDL-cholesterol contents in hyperlipidemia.

• The Journal of Internal Korean Medicine
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• v.27 no.1
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• pp.16-26
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• 2006

Objectives : This experiment was performed to determine the effects of the Jeseubsungi-tang(JSSGT) on hyperlipidemia-induced by hypercholesterolemic diet in mice. Methods : C57BL/6 mice were sensitized with a hypercholesterolemic diet for 6 weeks. Experimental group was treated with $150mg/d{\ell}$ concentrations of JSSGT for 4 weeks (once a day). Results: JSSGT-treated mice showed a body weight decrease compared to normal group. JSSGT-treated mice showed a significant decrease in cholesterol, total cholesterol, triglyceride, ALT and LDL-cholesterol levels compared to hyperlipidemia-induced control group. However, HDL-cholesterol levels in JSSGT-treated group significantly increased compared to the hyperlipidemia-induced control group. Conclusion : These results suggest that JSSGT is effective in treating hyperlipidemia. Because only hyperlipidemic mice were studied, further research is needed.

• Journal of Pharmacopuncture
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• v.10 no.1 s.22
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• pp.109-119
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• 2007

In order to study the effects of Pinus densiflora on hyperlipidemia and lipid in rats, we divided the rats into groups(Normal group, Control group and Sample group) and perfomed the experimental research. Hyperlipidemia and lipid in rats were induced by high fat diets for 8weeks. The sample group was administerd the extract of Pinus densiflora for 14 days and control group was administerd equal dose of oral. And then we measured the amount of serum triglyceride, Total cholesterol, LDL-cholesterol, HDL-cholesterol, Free Fatty Acid, phospholipid, Insuline, Laptin, Body weight, epididymis fat weight & rate, epididymis fat cell, Cardiac Risk Factor(CRF). The results were as followers : 1. Sample Group showed decreasing effects on Total cholesterol, Trigylceride, LDL-cholesterol, and Phospholipid levels in serum and CRF significantly. 2. Sample Group showed increasing effects on HDL-cholesterol level in serum significantly. 3. Sample Group showed decreasing effects on Insuline in serum significantly. 4. Sample Group showed increasing effects on Laptin in serum significantly. 5. Sample Group showed decreasing effects on Body weight, epididymis fat weight & rate, epididymis fat cell significantly. According to the above results, Pinus densiflora showed significant decreasing effects on hyperlipidemia and lipid in rats, it is considered that it is appropriate to apply for hyperlipidemia, obesity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.372-376
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• 2006

In order to study the effects of Cervi pantotrichum on hyperlipidemia, we divided the rats into three groups (normal group, control group & sample group) and perfomed the experimental research. Hyperlipidemia rat was induced by olive oil $1m{\ell}$(involved cholesterol 0.05g)/1200g for 10 days. The sample group was administerd the extract of Cervipantotrichum 10.8mg/200g for 5 days. and control group was administerd equal dose of saline. And then we measured the amount of serum total cholesterol, triglyceride, HDL-cholesterol, and phospholipid. Cervi pantotrichum showed decreasing effects on total cholesterol, LDL-cholesterol and phospholipid level, and increasing effects on HDL-cholesterol level in serum significantly. According to the above results, Cervi pantotrichum showed significant decreasing effects on hyperlipidemia, and it is considered that it is appropriate to apply for hyperlipidemia.

• Journal of Society of Preventive Korean Medicine
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• v.8 no.2
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• pp.185-202
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• 2004

In order to study the effects of Ojuck-san on hyperlipidemia, we divided the rats into three groups(normal group, control group & sample group) and performed the experimental research. Hyperlipidemia rats were induced by oral for 14days. The sample group was administerd the extract of Ojuck-san for 14 days and control group was administerd equal dose of oral. And then we measured the amount of serum Total cholesterol, Triglyceride, LDL-cholesterol, HDL-cholesterol, Phospholipid, Cholinesterase and Cardiac risk factor. The results were as follows : 1. Ojuck-san showed decreasing effects on Total cholesterol, Triglyceride, LDL -cholesterol, and Phospholipid level in serum significantly(p<0.001). 2. Ojuck-san showed increasing effects on HDL-cholesterol level and Cholinesterase in serum significantly(p<0.05). 3. Ojuck-san showed decreasing effects on Cardiac risk factor in serum significantly.(p<0.001). According to the above results, Ojuck-san showed significant decreasing effects on hyperlipidemia, and it is considered that it is appropriate to apply for hyperlipidemia.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.2
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• pp.319-327
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• 2010

This study was designed to investigate the hyperlipidemia-healing effect of liquid extract from Mageum-tang(麻芩湯), it was performed on the hyperlipidemia of rats induced by high cholesterol diet and Triton WR-1339. We prepared two types of hyperlipidemia model in rats induced by high cholesterol diet and Triton WR-1339. The amount of total cholesterol, HDL-cholesterol, LDL -cholesterol, triglyceride, phospholipid, free fatty acid, the activity of superoxide dismutase(SOD), and glutathione were measured. The liquid extract from Mageum-tang showed significant decreasing effects on total cholesterol, LDL- cholesterol, triglyceride, phospholipid, free fatty acid in the both model. And it showed significant increasing effects on HDL-cholesterol, the activity of SOD in both model and amount of glutathione in Triton WR-1339 model. These results suggest that liquid extract from Mageum-tang has healing efficacy on hyperlipidemia induced by high cholesterol diet and Triton WR-1339.

• The Journal of Korean Medicine
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• v.31 no.3
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• pp.122-127
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• 2010

Objective: Hyperlipidemia is a main risk factor of stroke and cardiovascular disease. This study aimed to investigate characteristics of hyperlipidemia in adult subjects. Methods: Hyperlipidemia-related makers were analyzed using biochemical data from 1,180 (496 male and 684 female) subjects who took medical examination in an Oriental Hospital for the purpose of detecting cerebrovascular accident. Results: 19.7 % of subjects (male 14.7 %, female 23.2 %) had hypercholesterolemia while 21.9 % (male 25.8 %, female 19.0 %) had hypertriglyceridemia. 17.2 % of subjects (male 22.1 %, female 13.6 %) showed low HDL-cholesterol while 13.0% (male 10.3 %, female 14.9 %) showed high LDL-cholesterol. Conclusions: This study will provide helpful information for patients with hyperlipidemia and to develop therapeutics using traditional Korean medicine.

• Korean Journal of Community Nutrition
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• v.8 no.6
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• pp.938-950
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• 2003

We conducted a case-control study to examine the relationship of depression and dietary related factors with the hyperlipidemia for urban living elderly women from low income group. The case group consisted of 45 elderly females with hyperlipidemia (serum cholesterol $\geq$ 240mg/dl or serum TG $\geq$ 250mg/dl and the control group of 95 age matched elderly women with serum cholesterol levels less than 240mg/dl and serum TG less than 250mg/dl. In a univariate analysis, vitamin C intake, the number of family members living with the subject, and their depression scores were significantly higher in the hyperlipidemic group than in the control group. In the logistic regression analysis, the vitamin C intake ($\geq$75% Korean RDA), the number of family members living with the subject ($\geq$ 1), depression scores ($\geq$7), BMI ($\geq$27), and subscapular skinfold thickness ($\geq$18mm) were associated with significantly higher (p<0.05) risks of hyperlipidemia in the elderly women. However after adjustment for other covariables, the depression scores (Odds Ratio 2.48 for depression score$\geq$7;95%CI:1.10-5.60) and subscapular skinfold thicknesses (Odds Ratio 5.69 for SBT$\geq$18mm, 95%CI:1.87-17.32) were the significant risk factors associated with hyperlipidemia in the elderly women.

• Journal of Society of Preventive Korean Medicine
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• v.8 no.1
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• pp.33-45
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• 2004

In order to study the effects of Typha angustata on hyperlipidemia, we divided the rats into three groups(normal group, control group & sample group) and perfomed the experimental research. Hyperlipidemia rats were induced by Triton WR-1339 for 3days. The sample group was administerd the extract of Typha angustata 2ml／200g for 3 days and control group was administerd equal dose of saline. And then we measured the amount of serum Total cholesterol, Triglyceride, LDL-cholesterol, HDL-cholesterol, and Phospholipid. The results were as follows: 1. Typha angustata showed decreasing effects on Total cholesterol, Triglyceride, LDL-cholesterol, and Phospholipid levels in serum significantly(p<0.01) 2. Typha angustata showed and showed increasing effects on HDL-cholesterol level in serum significantly(p<0.05). According to the above results, Typha angustata showed significant decreasing effects on hyperlipidemia, and it is considered that it is appropriate to apply for hyperlipidemia.