• Biomolecules & Therapeutics
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• 제25권4호
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• pp.390-395
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• 2017

The present study investigated the sedative effects of Sophora flavescens (SF) and its bioactive compound, matrine through performing locomotor activity test and the electroencephalography (EEG) analysis in the rat. The underlying neural mechanism of their beneficial effects was determined by assessing c-Fos immunoreactivity and serotonin (5-HT) in the brain utilizing immunohistochemical method and enzyme-linked immunosorbent assay. The results showed that SF and matrine administration had an effect on normalization of caffeine-induced hyperactivity and promoting a shift toward non-rapid eye movement (NREM) sleep. c-Fos-immunoreactivity and 5-HT level in the ventrolateral preoptic nucleus (VLPO), a sleep promoting region, were increased in the both SF and matrine-injected groups. In conclusion, SF and its bioactive compound, matrine alleviated caffeine-induced hyperactivity and promoted NREM sleep by activating VLPO neurons and modulating serotonergic transmission. It is suggested that SF might be a useful natural alternatives for hypnotic medicine.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제20권2호
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• pp.90-96
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• 2009

Objectives: This study examined clinical characteristics associated with bullying in children with attention-deficit/hyperactivity disorder(ADHD). Methods.: Children and their parents were asked to fill out a structured self-report form regarding bullying incidents. To evaluate the characteristics of the children, the results of the ADHD Rating Scale, the Korean version of the Child Behavior Checklist, the ADHD Diagnostic system and the Emotional Recognition Test were used. The agreement of bullying data between each child and their mother and father was measured using Cohen's kappa. The association between victim and perpetrator was analyzed by calculating a contingency coefficient based on chi-square. To compare the characteristics of victimized children and didn't, an independent sample T-test was performed. Results: When children were victims of bullying incidents there was significant agreement between children and parents on the information provided on the self-reports. However, more children reported themselves as a perpetrator of bullying than their parents did. Victimization, that is, the tendency towards being a perpetrator, is associated with the higher level of parental reports of aggressiveness. Conclusion: Victimization of bullying is associated with aggression in children with ADHD. This study suggests that victimized children with ADHD warrant careful evaluation, in particular with regard to the credence placed on parental reports of aggressiveness, and management for aggression.

• 대한한방소아과학회지
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• 제20권2호
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• pp.147-175
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• 2006

Objective : This study is to investigate the method for assesment and diagnosis of ADHD, especially focusing on behavior rating scales. Methods : We searched the recent date of the publication and paper in ADHD. Results : For Assesment and Diagnosis of ADHD, various method such as interview with parents, child and teacher, behavior observation, behavior rating scales and neuropsychological test are used. The structured interview consists of the restrictive questions and response, and then have diagnostic algorithm, consequently can be used by untrained clinicians. Of the structured interview, standardization of K-SADS in Korean version is finished. Behavior rating scales, the form of parent, teacher and self-report questionnaires, are used as diagnosis and treatment evaluation of ADHD. Behavior rating scales consist of both ADHD-specific scales and broad-band scales designed to screen for various symptoms (including ADHD symptoms). ADHD-specific scales are useful in differential diagnosis, discrimination of subtype, treatment evaluation, However, broad-band scales are useful in preliminary examination. The neuropsychological tests can evaluate attention deficit and effect of attention deficit on cognitive function and academic performance. The neuropsychological tests also used in diagnosis and treatment evaluation of ADHD. Conclusion : For Assesment and Diagnosis of ADHD, various method are used, especially behavior rating scales are both useful and simple tool for diagnosis and treatment evaluation.

• 대한의용생체공학회:의공학회지
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• 제23권2호
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• pp.155-163
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• 2002

Attention Deficit Hyperactivity Disorder(ADHD) is a childhood syndrome characterized by short attention span. impulsiveness, and hyperactivity, which often leadㄴ to learning disabilities and various behavioral problems. For the treatment of ADHD, medication and cognitive-behavior therapy is applied in recent yearn Although psycho-stimulant medication has been widely used for many rears. current findings suggest that, as the sole treatment for ADHD, it is an inadequate form of intervention in that parents don't want their child to use drug and the effects are limited to the period in which the drugs are physiologically active. On the other hand, EEG biofeedback treatment studies for ADHD have reported promising results not only in significant reductions in hyperactive, inattentive, and disruptive behaviors, but also improvements in academic performance and IQ scores. However it is too boring for children to finish the whole treatment. The recent increase in computer usage in medicine and rehabilitation has changed the way health care is delivered. Virtual Reality technology provides specific stimuli that can be used in removing distractions and providing environments that get the subjects'attention and increasing their ability to concentrate. VR technology can hold a patient's attention for a longer period of time than other methods can, because VR is immersive, interactive and imaginal. Based on these aspects, we developed Attention Enhancement System (AES) using VR technology, EEG biofeedback, and cognitive training method for enhancing attention and made a clinical trial to people who have attention difficulty and behavioral problems.

• 동의신경정신과학회지
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• 제17권3호
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• pp.157-164
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• 2006

Attention Deficit Hyperactivity Disorder(ADHD) is a psychiatric disorder, characterized by the primary symptoms of inattention and/or impulsivity and hyperactivity. This study is a clinical report of 1 ADHD child treated witb typical Oriental Medical Tberapy(Herb-med, acupunture, etc,) in Combination with Neurofeedback. Conner's parent rating scale, ADHD Diagnostic System were compared between before and after treatment. The results show the typical Oriental Medical Tberapy in Combination with Neurofeedback is efficient in the treatment of ADHD.

• 대한핵의학회지
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• 제7권1호
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• pp.31-38
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• 1973

The blood glucose and plasma immunoreactive insulin(IRI) levels were measured glucose tolerance test in 7 healthy subjects and 6 patients with chronic liver diseases. The glucose tolerance was impaired in 5 of the 6 patients and normal in 1. Plasma IRI responses were markedly increased and delayed in all patients, suggesting insulin resistance. Patients with more glucose intolerance showed less increase in plasma IRI than the group with less intolerance. It is suggested that some insulin antagonists may decrease the peripheral insulin sensitivity and stimulate compensatory hyperactivity of pancreatic islets. If the compensatory hyperactivity is inadequate due to genetic predisposition to diabetes mellitus or exhaustion of ${\beta}$-cells of pancreatic islsts, the glucose intolerance and overt diabetes mellitus may ensue.

• 대한가정학회지
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• 제36권8호
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• pp.123-140
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• 1998

The purpose of this study was to verify preschool children can be classified of Attention-Deficit Hyperactivity Disorder (ADHD) children across situation. It also was to examine differences among groups according to sex and age, and to investigate the family caracterisitcs of ADHD groups. The subjects of this study consisted of 228 preschool chilren (147 boys and 136 girls aged from 3- to 7- year-old) drawn from five Child Care Centers in Chung-Ju. Data were analyzed by the frequency, percentages, Cronbach's ${\alpha}$ coefficient, ${\chi}^2$-test, F-test, Tukey post-hoc test, and Pearson correlation using SAS program. The results were as follows: 1. Preschool children could be classified by four diagnostic groups across situation; (1) 168 children (59%) of the control group (no disorder of ADHD), (2) 49 children (17%) of ADHD-Home group (ADHD only at home), (3) 43 children (15%) of ADHD-School group (ADHD only at school), and (4) 23 children (8%) of ADHD-PH group (ADHD both at home and at school). Ratings by parents and by teachers correlated very low with each other, as in previous studies. These results confirm the findings that ADHD be classified across situation. 2. There were significant differences among four groups according to sex and age. In the ADHD-PH groups, the boys is 3 times higher than the girls and the children aged 6- to 7-year-old was shown highly distributed in the pervasive ADHD.

• Child Health Nursing Research
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• 제14권3호
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• pp.243-251
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• 2008

Objective: School nurses should be knowledgeable about attention-deficit hyperactivity disorder (ADHD) and have tolerant attitudes to children with ADHD. This study was done to identify school nurses' knowledge about, and attitudes to, ADHD. Methods: A cross-sectional descriptive correlational study was conducted. The participants were the 245 members of a school nurse association in C province in southern part of Korea. Data were collected using a self-report questionnaire. Descriptive statistics, t-test, ANOVA, and Pearson correlation coefficients were used to analyze the data. Results: Of the 245 packets mailed to members, 126 (51.4%) were returned, and of these, 122 packets (49.8%) were suitable for data analysis. School nurses in this study lack knowledge about ADHD. Moreover, school nurses reported low tolerance in their attitudes toward children with ADHD. There was no significant correlation between knowledge and attitudes in the management of ADHD among school nurses. Conclusion: Findings from this study show that school nurses have limited knowledge about ADHD and its treatment with stimulation medication. Moreover, their attitudes toward children with ADHD were in the low tolerant range. An educational program on ADHD for school nurses need to be developed and provided to facilitate the school nurses' role in assessing and caring for children with ADHD.

• 한국전자통신학회논문지
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• 제15권2호
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• pp.285-290
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• 2020

뉴로피드백(Neuro feedback)은 자신의 뇌 상태를 파악하고, 뇌 상태를 의도적으로 변화시킬 수 있다는 기술로, 주의력 결핍 및 과잉 행동 장애를 겪는 사람에게 그 필요성이 대두됨에도 불구하고, 기존의 뉴로피드백 훈련은 정적인 상태를 장시간 유지하며 흥미를 주지 못하는 문제가 있었다. 따라서, 본 논문에서는 집중력 강화를 위하여 뉴로피드백과 건-슈팅 게임을 결합하는 뉴로피드백 게임을 제안 및 구현하였다. 뇌파 측정 시스템, 게임제어기 그리고 게임소프트의 설계로 뉴로피드백 게임이 구현되었으며, 본 연구로 주의력 결핍 및 과잉 행동 장애를 겪는 사람에게 뉴로피드백 훈련이 유용하게 사용되기를 기대한다.

• 생물정신의학
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• 제26권2호
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• pp.59-64
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• 2019

Objectives Internet gaming disorder (IGD) is associated with attention deficit/hyperactivity disorder (ADHD) or depression etc. We tried to examine the mediating effects of depression in the relationship between ADHD and IGD. Methods This study was conducted on 2000 people who participated in on-line survey among 14-39 year-old men and women in 2017. And we clarified the relationship among IGD, ADHD, and depression and tested the mediation model. The mean and standard deviation of the main variables were calculated and correlation analysis was performed to confirm the relationship among the main variables. In order to test the mediating effect of depression on the relationship between ADHD and IGD, the structural equation model was implemented using AMOS 21 (IBM). Results There were significant correlations among the variables; IGD, ADHD and depression. Depression had a mediating effect 0.23 (95% confidence interval : 0.17-0.28) in the relationship between IGD and ADHD. Conclusions This study showed that depression can mediate ADHD and IGD. Therefore, the evaluation and management of depression and ADHD should be included in the diagnosis and treatment of IGD.