• 한국수산과학회지
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• 제56권6호
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• pp.850-860
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• 2023

The effects of dietary mannan oligosaccharides, Lactobacillus plantarum, Bacillus subtilis, and Bacillus licheniformis supplementation on hybrid grouper Epinephelus akaara ♀×Epinephelus lanceolatus ♂ were evaluated. The fish were fed a basal diet and five other diets consisting of 0.6% mannan oligosaccharides, L. plantarum, B. subtilis, and B. licheniformis and mixture of each 0.15% prebiotic and all the probiotics (designated as MOS, LP, BS, BL, and SYN) for 56 days. Growth performance and feed utilization showed no significant differences among all experimental groups. Lipid level of whole-body was significantly high in MOS and BL groups. Plasma aspartate aminotransferase was significantly low in BL and SYN groups. Nitro-blue tetrazolium, lysozyme and anti-protease, and glutathione peroxidase in BS, SYN, and all probiotic groups, respectively, were significantly high. Intestinal Vibrio bacteria was significantly low in all probiotic and SYN groups. Gene expression of interleukin-1β and interleukin-10 in SYN group; transforming growth factor β2 in MOS and BS groups, toll-like receptor 2-2 in BS and BL groups; and C-type lectin in MOS, LP and SYN groups were significantly upregulated. Our findings indicate that mannan oligosaccharides, L. plantarum, B. subtilis, and B. licheniformis could improve innate immunity, antioxidant capacity, anti-inflammation, and intestinal microbiota of hybrid grouper.

• Journal of Power Electronics
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• 제15권5호
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• pp.1367-1379
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• 2015

A hybrid HVDC system that is composed of line commutated converter (LCC) at the rectifier side and voltage source converter (VSC) in series with LCC at the inverter side is studied in this paper. The start-up strategy, DC fault ride-through capability, and fault recovery strategy for the hybrid HVDC system are proposed. The steady state and dynamic performances under start-up, AC fault, and DC fault scenarios are analyzed based on a bipolar hybrid HVDC system. Furthermore, the immunity of the LCC inverter in hybrid HVDC to commutation failure is investigated. The simulation results in PSCAD/EMTDC show that the hybrid HVDC system exhibits favorable steady state and dynamic performances, in particular, low susceptibility to commutation failure, excellent DC fault ride-through, and fast fault recovery capability. Results also indicate that the hybrid HVDC system can be a good alternative for large-capacity power transmission over a long distance byoverhead line.

• 대한전자공학회논문지SD
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• 제48권8호
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• pp.10-17
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• 2011

휴대용 전자 기기 수요가 증가하면서 저전력 회로에 대한 관심이 커지고 있다. 이와 더불어 프로세서 데이터 패스의 폭이 넓어지고, 파이프라인의 단계가 많아짐에 따라, 사용되는 플립플롭의 수가 증가하였다. 그로 인해 플립플롭의 전력 소모 및 성능이 전체 시스템에 미치는 영향이 커졌다. 또한, 반도체 공정 스케일이 점점 줄면서, 공급 전압과 문턱 전압이 감소되었고 이로 인해 노이즈가 회로에 미치는 영향이 커지고 있다. 본 논문에서는 노이즈 면역을 향상시키면서도 저전력 시스템에 사용할 수 있는 플립플롭을 제안하고자 한다. 제안한 회로는 1.2V에서 동작하는 65nm CMOS 공정으로 구현하였다.

• 전자공학회논문지A
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• 제28A권11호
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• pp.855-865
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• 1991

A simple method for analysis of serial search burst-format direct-sequence spread-spectrum (DS-SS) code acquisition system had been recently proposed, and therein, the effect of the code autocorrelation sidelobes on the performance of DS-SS code acquisition system has been assessed [4],[5]. In this paper, a new hybrid scheme which combines the serial search with maximum likelihood search is proposed to eliminate the deleterious effect of code autocorrelation sidelobes, and the performance is analyzed for the additive withe Gaussian noise (AWGN) channels. To analyze the performance of this system, we have generalized the method used in [4],[5] to arbitrary burst-format DS-SS acquisition schemes. The results show that a new hybrid scheme has good immunity against the effect of code autocorrelation sidelobes. Thevalidity of the presented approach has been confirmed form the results of simulation.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 1999년도 춘계종합학술대회
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• pp.425-431
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• 1999

본 연구에서는 플라즈마 감시에 의한 용접성 평가방식을 채택한다. 플라즈마에서 발생하는 자외선신호를 반도체 광센서를 사용하여 검출하고, 감시장치로 쓰이는 개인용 컴퓨터에 고속으로 전달, 저장하는 장치를 개발한다. 이 장치를 사용하여 용접 데이터베이스를 구축하고, 용접성과 플라즈마 신호와의 관계를 평가하고, 분석할 것이다. 이 분야에 대한 연구동향을 하면 표2와 같다. 그러나 이 연구들은 모두 사용한 장치의 특성, 플라즈마발생원에 대한 센서의 상대적 위치 및 자세와 획득 신호와의 관계, 용접할 때 발생하는 열의 센서에 대한 영향, 잡음이 취득된 신호에 미치는 영향 및 회피방법 둥에 대한 언급이 없다. 따라서 논문에 실린 신호의 파형은 대부분 일관성이 없으며, 참고가 어렵다. 본 연구에서는 이러한 관계를 도출하고, 특히 잡음의 영향을 최소화하는 장치화에 주안점을 둔다.

• Molecules and Cells
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• 제39권5호
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• pp.426-438
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• 2016

Plant disease resistance occurs as a hypersensitive response (HR) at the site of attempted pathogen invasion. This specific event is initiated in response to recognition of pathogen-associated molecular pattern (PAMP) and subsequent PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI). Both PTI and ETI mechanisms are tightly connected with reactive oxygen species (ROS) production and disease resistance that involves distinct biphasic ROS production as one of its pivotal plant immune responses. This unique oxidative burst is strongly dependent on the resistant cultivars because a monophasic ROS burst is a hallmark of the susceptible cultivars. However, the cause of the differential ROS burst remains unknown. In the study here, we revealed the plausible underlying mechanism of the differential ROS burst through functional understanding of the Magnaporthe oryzae (M. oryzae) AVR effector, AVR-Pii. We performed yeast two-hybrid (Y2H) screening using AVR-Pii as bait and isolated rice NADP-malic enzyme2 (Os-NADP-ME2) as the rice target protein. To our surprise, deletion of the rice Os-NADP-ME2 gene in a resistant rice cultivar disrupted innate immunity against the rice blast fungus. Malic enzyme activity and inhibition studies demonstrated that AVR-Pii proteins specifically inhibit in vitro NADP-ME activity. Overall, we demonstrate that rice blast fungus, M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice. This characterization of the regulation of the host oxidative burst will help to elucidate how the products of AVR genes function associated with virulence of the pathogen.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2001년도 추계학술대회 논문집
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• pp.286-290
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• 2001

This paper presents a full-digital low-level controller for a robotic material transfer system which has been developed for a computer-integrated manufacturing model plant. Compared to conventional analog or hybrid type controllers in current industrial environments, this controller system has some advantages such as strong noise-immunity, easy control algorithm implementation, etc The servo-controller consists of two modules, a position controller and a DC servo motor driver. The position controller operates position feedback routines by receiving position encoder data and sending control outputs to the driver. The position controller is implemented in a full-digital way using a recently introduced microcontroller. The DC servomotor driver controls speeds and torques. The driver consists of a micro-controller and insulated-gate-bipolar-transistors (IGBT). The micro-controller provides control signals, and the IGBT's amplifies the control signals and sends them to the motor.

• Journal of Microbiology and Biotechnology
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• 제31권12호
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• pp.1601-1614
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• 2021

To overcome the ongoing COVID-19 pandemic, vaccination campaigns are the highest priority of majority of countries. Limited supply and worldwide disproportionate availability issues for the approved vaccines, together with concerns about rare side-effects have recently initiated the switch to heterologous vaccination, commonly known as mixing of vaccines. The COVID-19 vaccines are highly effective in the general population. However, none of the vaccines is 100% efficacious or effective, with variants posing more challenges, resulting in breakthrough cases. This review summarizes the current knowledge of immune responses to variants of concern (VOC) and breakthrough infections. Furthermore, we discuss the scope of heterologous vaccination and future strategies to tackle the COVID-19 pandemic, including fractionation of vaccine doses and alternative route of vaccination.

• 한국컴퓨터정보학회논문지
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• 제14권10호
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• pp.159-166
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• 2009

자연면역 시스템은 여러 신체 부위에서 다양한 기능으로 외부침입에 민감하게 대응할 뿐만 아니라 기존에 감염된 정보를 기억하는 기능을 수행한다. 그러나 자연 면역 시스템의 원리를 적용한 컴퓨터 보안 시스템에서는 자연면역 시스템이 갖는 기능을 충분히 제공하지 못하는 문제점이 있다. 이 논문에서는 자연면역 시스템의 네거티브 셀렉션을 적용한 항체와 임의의 비정상 시스템 콜 시퀀스를 선택하여 유전자 알고리즘을 적용한 항체를 결합하여 자연면역 시스템과 유사한 기능을 제공하는 하이브리드 모델을 제안한다. 제안된 모델은 긍정적 결함과 부정적 결함을 줄이기 위해 임의의 비정상 시스템 콜 시퀀스를 이용한다. 실험에 사용된 데이터는 UNM(University of New Maxico)에서 제공된 샌드메일 데이터이며 실험 결과 제안 모델은 기존 네거티브 셀렉션보다 비정상 시스템 콜을 정상 시스템 콜로 판정하는 부정적 결함이 평균 0.55% 낮게 나타났다.

• Journal of Computing Science and Engineering
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• 제5권2호
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• pp.121-130
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• 2011

Recent research indicates that transient errors will increasingly become a critical concern in microprocessor design. As embedded processors are widely used in reliability-critical or noisy environments, it is necessary to develop cost-effective fault-tolerant techniques to protect processors against transient errors. The register file is one of the critical components that can significantly affect microprocessor system reliability, since registers are typically accessed very frequently, and transient errors in registers can be easily propagated to functional units or the memory system, leading to silent data error (SDC) or system crash. This paper focuses on investigating the impact of register file soft errors on system reliability and developing cost-effective techniques to improve the register file immunity to soft errors. This paper proposes the register vulnerability factor (RVF) concept to characterize the probability that register transient errors can escape the register file and thus potentially affect system reliability. We propose an approach to compute the RVF based on register access patterns. In this paper, we also propose two compiler-directed techniques and a hybrid approach to improve register file reliability cost-effectively by lowering the RVF value. Our experiments indicate that on average, RVF can be reduced to 9.1% and 9.5% by the hyperblock-based instruction re-scheduling and the reliability-oriented register assignment respectively, which can potentially lower the reliability cost significantly, without sacrificing the register value integrity.