• Title/Summary/Keyword: hybrid immunity

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Effects of Dietary Prebiotic, Probiotics and Synbiotic on Growth, Nonspecific Immunity, Antioxidant Capacity, Intestinal Microbiota and Antiinflammatory Activity of Hybrid Grouper (Epinephelus akaara ♀×Epinephelus lanceolatus ♂) (사료 내 Prebiotic, Probiotics와 Synbiotic의 첨가가 대왕붉바리(Epinephelus akaara ♀×Epinephelus lanceolatus ♂)의 성장, 비특이적 면역력, 항산화능, 장내 미생물 조성과 항염증에 미치는 영향)

  • Wonhoon Kim;Jongho Lim;Minjoo Kang;Choong Hwan Noh;Kyeong-Jun Lee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.6
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    • pp.850-860
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    • 2023
  • The effects of dietary mannan oligosaccharides, Lactobacillus plantarum, Bacillus subtilis, and Bacillus licheniformis supplementation on hybrid grouper Epinephelus akaara ♀×Epinephelus lanceolatus ♂ were evaluated. The fish were fed a basal diet and five other diets consisting of 0.6% mannan oligosaccharides, L. plantarum, B. subtilis, and B. licheniformis and mixture of each 0.15% prebiotic and all the probiotics (designated as MOS, LP, BS, BL, and SYN) for 56 days. Growth performance and feed utilization showed no significant differences among all experimental groups. Lipid level of whole-body was significantly high in MOS and BL groups. Plasma aspartate aminotransferase was significantly low in BL and SYN groups. Nitro-blue tetrazolium, lysozyme and anti-protease, and glutathione peroxidase in BS, SYN, and all probiotic groups, respectively, were significantly high. Intestinal Vibrio bacteria was significantly low in all probiotic and SYN groups. Gene expression of interleukin-1β and interleukin-10 in SYN group; transforming growth factor β2 in MOS and BS groups, toll-like receptor 2-2 in BS and BL groups; and C-type lectin in MOS, LP and SYN groups were significantly upregulated. Our findings indicate that mannan oligosaccharides, L. plantarum, B. subtilis, and B. licheniformis could improve innate immunity, antioxidant capacity, anti-inflammation, and intestinal microbiota of hybrid grouper.

Investigation of a Hybrid HVDC System with DC Fault Ride-Through and Commutation Failure Mitigation Capability

  • Guo, Chunyi;Zhao, Chengyong;Peng, Maolan;Liu, Wei
    • Journal of Power Electronics
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    • v.15 no.5
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    • pp.1367-1379
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    • 2015
  • A hybrid HVDC system that is composed of line commutated converter (LCC) at the rectifier side and voltage source converter (VSC) in series with LCC at the inverter side is studied in this paper. The start-up strategy, DC fault ride-through capability, and fault recovery strategy for the hybrid HVDC system are proposed. The steady state and dynamic performances under start-up, AC fault, and DC fault scenarios are analyzed based on a bipolar hybrid HVDC system. Furthermore, the immunity of the LCC inverter in hybrid HVDC to commutation failure is investigated. The simulation results in PSCAD/EMTDC show that the hybrid HVDC system exhibits favorable steady state and dynamic performances, in particular, low susceptibility to commutation failure, excellent DC fault ride-through, and fast fault recovery capability. Results also indicate that the hybrid HVDC system can be a good alternative for large-capacity power transmission over a long distance byoverhead line.

A Flipflop with Improved Noise Immunity (노이즈 면역을 향상시킨 플립플롭)

  • Kim, Ah-Reum;Kim, Sun-Kwon;Lee, Hyun-Joong;Kim, Su-Hwan
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.48 no.8
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    • pp.10-17
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    • 2011
  • As the data path of the processor widens and the depth of the pipeline deepens, the number of required registers increases. Consequently, careful attention must be paid to the design of clocked storage elements like latches and flipflops as they have a significant bearing on the overall performance of a synchronous VLSI circuit. As technology is also scaling down, noise immunity is becoming an important factor. In this paper, we present a new flipflop which has an improved noise immunity when compared to the hybrid latch flipflop and the conditional precharge flipflop. Simulation results in 65nm CMOS technology with 1.2V supply voltage are used to demonstrate the effectiveness of the proposed flipflop structure.

Performance Analysis of Burst-Format DS-SS Acquisition system Using a Serial-Maximum Likelihood Search- A Modified State Transition diagram Approach (직렬-최대 공차 탐색을 사용한 비스트형 DS-SS 초기 동기 시스템의 성능 분석-수정된 상태 천이도 접근법-)

  • 이독욱;김근묵;황금찬
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.28A no.11
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    • pp.855-865
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    • 1991
  • A simple method for analysis of serial search burst-format direct-sequence spread-spectrum (DS-SS) code acquisition system had been recently proposed, and therein, the effect of the code autocorrelation sidelobes on the performance of DS-SS code acquisition system has been assessed [4],[5]. In this paper, a new hybrid scheme which combines the serial search with maximum likelihood search is proposed to eliminate the deleterious effect of code autocorrelation sidelobes, and the performance is analyzed for the additive withe Gaussian noise (AWGN) channels. To analyze the performance of this system, we have generalized the method used in [4],[5] to arbitrary burst-format DS-SS acquisition schemes. The results show that a new hybrid scheme has good immunity against the effect of code autocorrelation sidelobes. Thevalidity of the presented approach has been confirmed form the results of simulation.

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Development of Plasma Monitoring System for Laser Welding Quality Analysis (레이저 용접품질 해석용 플라즈마 감시장치 개발)

  • 권장우;권오상;장영건;이경돈;홍승홍
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 1999.05a
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    • pp.425-431
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    • 1999
  • We develope plasma monitoring system which detect plasma signals and store them for Laser welding quality evaluation and analysis using photo detector. The most fundamental and important aspects in such a system are signal restoration fidelity, noise immunity and noise cancelation capability. In this paper, we propose implementation method using distribute processing structure and hybrid digital communication for high noise cancelation capability, immunity and signal fidelity which are poorly presented in other researches. Lab experimental results and welding experimental results show a effectiveness of proposed method and plasma data is stored with 256 kbps without any communication error. we are implementing various welding defect recognition algorithm in this system.

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Magnaporthe oryzae Effector AVR-Pii Helps to Establish Compatibility by Inhibition of the Rice NADP-Malic Enzyme Resulting in Disruption of Oxidative Burst and Host Innate Immunity

  • Singh, Raksha;Dangol, Sarmina;Chen, Yafei;Choi, Jihyun;Cho, Yoon-Seong;Lee, Jea-Eun;Choi, Mi-Ok;Jwa, Nam-Soo
    • Molecules and Cells
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    • v.39 no.5
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    • pp.426-438
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    • 2016
  • Plant disease resistance occurs as a hypersensitive response (HR) at the site of attempted pathogen invasion. This specific event is initiated in response to recognition of pathogen-associated molecular pattern (PAMP) and subsequent PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI). Both PTI and ETI mechanisms are tightly connected with reactive oxygen species (ROS) production and disease resistance that involves distinct biphasic ROS production as one of its pivotal plant immune responses. This unique oxidative burst is strongly dependent on the resistant cultivars because a monophasic ROS burst is a hallmark of the susceptible cultivars. However, the cause of the differential ROS burst remains unknown. In the study here, we revealed the plausible underlying mechanism of the differential ROS burst through functional understanding of the Magnaporthe oryzae (M. oryzae) AVR effector, AVR-Pii. We performed yeast two-hybrid (Y2H) screening using AVR-Pii as bait and isolated rice NADP-malic enzyme2 (Os-NADP-ME2) as the rice target protein. To our surprise, deletion of the rice Os-NADP-ME2 gene in a resistant rice cultivar disrupted innate immunity against the rice blast fungus. Malic enzyme activity and inhibition studies demonstrated that AVR-Pii proteins specifically inhibit in vitro NADP-ME activity. Overall, we demonstrate that rice blast fungus, M. oryzae attenuates the host ROS burst via AVR-Pii-mediated inhibition of Os-NADP-ME2, which is indispensable in ROS metabolism for the innate immunity of rice. This characterization of the regulation of the host oxidative burst will help to elucidate how the products of AVR genes function associated with virulence of the pathogen.

생산공장용 무궤도 무인운반차 개발

  • 한석균;김용일;강무진
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2001.10a
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    • pp.286-290
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    • 2001
  • This paper presents a full-digital low-level controller for a robotic material transfer system which has been developed for a computer-integrated manufacturing model plant. Compared to conventional analog or hybrid type controllers in current industrial environments, this controller system has some advantages such as strong noise-immunity, easy control algorithm implementation, etc The servo-controller consists of two modules, a position controller and a DC servo motor driver. The position controller operates position feedback routines by receiving position encoder data and sending control outputs to the driver. The position controller is implemented in a full-digital way using a recently introduced microcontroller. The DC servomotor driver controls speeds and torques. The driver consists of a micro-controller and insulated-gate-bipolar-transistors (IGBT). The micro-controller provides control signals, and the IGBT's amplifies the control signals and sends them to the motor.

A Promising Vaccination Strategy against COVID-19 on the Horizon: Heterologous Immunization

  • Mattoo, Sameer-ul-Salam;Myoung, Jinjong
    • Journal of Microbiology and Biotechnology
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    • v.31 no.12
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    • pp.1601-1614
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    • 2021
  • To overcome the ongoing COVID-19 pandemic, vaccination campaigns are the highest priority of majority of countries. Limited supply and worldwide disproportionate availability issues for the approved vaccines, together with concerns about rare side-effects have recently initiated the switch to heterologous vaccination, commonly known as mixing of vaccines. The COVID-19 vaccines are highly effective in the general population. However, none of the vaccines is 100% efficacious or effective, with variants posing more challenges, resulting in breakthrough cases. This review summarizes the current knowledge of immune responses to variants of concern (VOC) and breakthrough infections. Furthermore, we discuss the scope of heterologous vaccination and future strategies to tackle the COVID-19 pandemic, including fractionation of vaccine doses and alternative route of vaccination.

A Hybird Antibody Model Design using Genetic Algorithm Scheme (유전 알고리즘 기법을 이용한 HA 모델 설계)

  • Shin, Mi-Yea;Jeon, Seoung-Heup;Lee, Sang-Ho
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.10
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    • pp.159-166
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    • 2009
  • A nature immunity system responds sensitively to an external invasion with various functions in a lot of bodies, besides it there is a function to remember information to have been currently infected. we propose a hybrid model similar to immune system which combine with the antibody which applied genetic algorithm as select antibody and the arbitrary abnormal system call sequence that applied negative selection of a nature immunity system. A proposed model uses an arbitrary abnormal system Kol sequence in order to reduce a positive defect and a negative defect. Data used to experiment are send mail data processed UNM (University of New Maxico). The negative defect that an experiment results proposal model judged system call more abnormal than the existing negative selection to normal system call appeared 0.55% low.

Computing and Reducing Transient Error Propagation in Registers

  • Yan, Jun;Zhang, Wei
    • Journal of Computing Science and Engineering
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    • v.5 no.2
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    • pp.121-130
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    • 2011
  • Recent research indicates that transient errors will increasingly become a critical concern in microprocessor design. As embedded processors are widely used in reliability-critical or noisy environments, it is necessary to develop cost-effective fault-tolerant techniques to protect processors against transient errors. The register file is one of the critical components that can significantly affect microprocessor system reliability, since registers are typically accessed very frequently, and transient errors in registers can be easily propagated to functional units or the memory system, leading to silent data error (SDC) or system crash. This paper focuses on investigating the impact of register file soft errors on system reliability and developing cost-effective techniques to improve the register file immunity to soft errors. This paper proposes the register vulnerability factor (RVF) concept to characterize the probability that register transient errors can escape the register file and thus potentially affect system reliability. We propose an approach to compute the RVF based on register access patterns. In this paper, we also propose two compiler-directed techniques and a hybrid approach to improve register file reliability cost-effectively by lowering the RVF value. Our experiments indicate that on average, RVF can be reduced to 9.1% and 9.5% by the hyperblock-based instruction re-scheduling and the reliability-oriented register assignment respectively, which can potentially lower the reliability cost significantly, without sacrificing the register value integrity.