• 제목/요약/키워드: humans

검색결과 3,973건 처리시간 0.03초

Human Cytochrome P450 Metabolic Activation in Chemical Toxicity

  • Kim, Dong-Hak;Chun, Young-Jin
    • Toxicological Research
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    • 제23권3호
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    • pp.189-196
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    • 2007
  • Cytochrome P450 (P450) enzymes are the major catalysts involved in the biotransformation of various drugs, pollutants, carcinogens, and many endogenous compounds. Most of chemical carcinogens are not active by themselves but they require metabolic activation. P450 isozymes playa pivotal role in the metabolic activation. The activation of arylamines and heterocyclic arylamines (HAAs) involves critical N-hydroxylation, usually by P450. CYP1A2 plays an important role in these reactions. Broad exposure to many of these compounds might cause carcinogenicity in animals and humans. On the other hand, P450s can be also involved in the bioactivation of other chemicals including alcohols, aflatoxin B1, acetaminophen, and trichloroethylene, both in humans and in experimental animals. Understanding the P450 metabolic activation of many chemicals is necessary to develop rational strategies for prevention of their toxicities in human health. An important part is the issues of extrapolation between species in predicting risks and variation of P450 enzyme activities in humans.

A Human Robot Interactive System "RoJi"

  • Shim, Inbo;Yoon, Joongsun;Yoh, Myeungsook
    • International Journal of Control, Automation, and Systems
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    • 제2권3호
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    • pp.398-405
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    • 2004
  • A human-friendly interactive system that is based on the harmonious symbiotic coexistence of humans and robots is explored. Based on the interactive technology paradigm, a robotic cane is proposed for blind or visually impaired pedestrians to navigate safely and quickly through obstacles and other hazards. Robotic aids, such as robotic canes, require cooperation between humans and robots. Various methods for implementing the appropriate cooperative recognition, planning, and acting, have been investigated. The issues discussed include the interaction between humans and robots, design issues of an interactive robotic cane, and behavior arbitration methodologies for navigation planning.

The Facts That We Have Been Mistaken About Our Minds, Language, and Octopuses; "Other Minds: The Octopus, The Sea, and The Deep Origins of Consciousness"

  • Son, Jung-Woo
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제32권4호
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    • pp.170-172
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    • 2021
  • To date, we have made inferences on the behavior and mind of humans and animals from the perspective of humans, or for the sake of familiarity, vertebrates. The book, "Other Minds; The Octopus, The Sea, and The Deep Origins of Consciousness" by Peter Godfrey-Smith makes us realize how erroneous preconceived notions could be, and presents a novel perspective on the results of evolution. Throughout this book, readers will learn about the characteristics of the nervous system, behavior, and habits of cephalopods, which include octopuses. Through this book, readers will gain a new perspective on the embodiment, minds, nervous systems, consciousness, and sociality of humans and animals. Furthermore, the book will provide the imaginary experience of swimming in "Octopolis" inside the ocean with the author.

A Systematic Review on Human Factors in Cybersecurity

  • Alghamdi, Ahmed
    • International Journal of Computer Science & Network Security
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    • 제22권10호
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    • pp.282-290
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    • 2022
  • A huge budget is spent on technological solutions to protect Information Systems from cyberattacks by organizations. However, it is not enough to invest alone in technology-based protection and to keep humans out of the cyber loop. Humans are considered the weakest link in cybersecurity chain and most of the time unaware that their actions and behaviors have consequences in cyber space. Therefore, humans' aspects cannot be neglected in cyber security field. In this work we carry out a systematic literature review to identify human factors in cybersecurity. A total of 27 papers were selected to be included in the review, which focuses on the human factors in cyber security. The results show that in total of 14 identified human factors, risk perception, lack of awareness, IT skills and gender are considered critical for organization as for as cyber security is concern. Our results presented a further step in understanding human factors that may cause issues for organizations in cyber space and focusing on the need of a customized and inclusive training and awareness programs.

불교철학과 대순사상의 사유체계에 대한 일고찰 - 우주관·인간관·이상사회관을 중심으로 - (Reflection on the Thinking System of Buddhist Philosophy and Daesoon Philosophy)

  • 이덕진
    • 대순사상논총
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    • 제20권
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    • pp.223-272
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    • 2009
  • Both Daesoon philosophy and Buddhist philosophy have strong aspirations for establishing a world comprised of human-beings. In other words, Daesoon philosophy and Buddhist philosophy put human-beings in the place of 'subject character(主語的 人格)' instead of 'predicate character(述語的 人格).' This is because a human is the master rather than a guest of the universe and the world. In this regard, it is safe to say that both Daesoon philosophy and Buddhist philosophy have a common goal of reaching 'an infinitely open life managed by a human-being, the master.' Daesoon philosophy and Buddhist philosophy also share the idea that everything in the universe is an organistic world that is closely connected, like a network. In this aspect, the two philosophies consider the whole world rather than the individual, and seek ways for people to live together actively while expanding the scope of community to the world. Even if 'the morality of living together (相生)' and 'the realization of mercy(同體大悲)' are completely different languages on the surface, it is not difficult to understand the homogeneity inherent in such expressions. Daesoon philosophy and Buddhist philosophy show endless reliability towards all humans and are declarative and reasonable, but both herald human beings as eligible to become the main characters of the future world and lead to the birth of independent human beings while inducing them to the highest position in the universe by liberating humans from the limitations they find. 'Heaven on Earth' as stated in Daesoon philosophy refers to an ideal society where humans and God harmonize, and God and humans complement each other. Also, the world will achieve political stability and equality, realizing an economically prosperous world. Furthermore, social justice will be realized and cultural and religious conflicts resolved. As humans acknowledge there is a way to live together in a universal nature, the environmental issue no longer becomes the top priority for human beings and a world where the morals of human beings reach the highest level will be established. From the original Buddhist perspective, King Jeonrhyun, the proxy of Buddha, realizes the ideal of Buddhism in the mundane world. The world controlled by King Jeonrhyun can be described as having liberty, equality, peace, justice, prosperity, morality, order, legality, democracy, welfare, etc. Therefore, the ideal Buddhist world is materially prosperous, physically healthy and socially just, as well as a world where moral maturity and mental freedom are achieved.

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Character Animation of Realistic Humans

  • Edwina Quek;Pei, Lim-Jun;Seng, Lai-Looi;Cui Jing;Edmond C. Prakash;Edmund M-K. Lai
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2001년도 ICCAS
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    • pp.165.3-165
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    • 2001
  • Animation of 3-dimensional humans is a challenging task, however, its realistic synthesis is possible. Essentially, the nature of this project is to demonstrate and study the difficulties faced by an animator in making a movie with a state of art computer animation software (Maya Software by ,alias/wavefront) by creating a movie clip with the above-stated software ourselves. We will also analyze the aspect of automated animation to relieve the animator of some very tedious tasks.

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Aviating with Multiple Intelligence

  • Anna Cybele Paschke
    • 한국항공운항학회지
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    • 제31권2호
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    • pp.108-115
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    • 2023
  • Alongside the rapid development of AI technology, which is stepping in to do tasks more quickly and less prone to error than humans can, the possibility for MI (multiple intelligence) development warrants equal attention and fervor. Recent theories of human intelligence point beyond standard cognitive capacity, IQ, and shine a light on the other unique potentials naturally endowed to humans. The applicability of MI to aviation is discussed, suggesting that it is important to consider ways to integrate MI development techniques into pilot education and training. Experiential starting points are discussed.

Progress Towards Control of a Mycobacterial Pathogen, Mycobacterium aviumsubsp. paratuberculosis, the Causative Agent of Johne's Disease in Cattle and Humans

  • Davis, William C.;Park, Kun Taek
    • 한국식품위생안전성학회지
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    • 제33권4호
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    • pp.221-228
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    • 2018
  • 19세기말 Mycobacterium avium subsp. paratuberculosis(Map)이 요네병(Johne's disease)의 원인균임이 밝혀진 이후, 불현성 감염된 동물들의 국제적 이동은 요네병을 전세계로 퍼뜨리기 시작하였다. 이러한 요네병이 축산분야에 나타남과 동시에 새로운 형태의 대장염으로서 요네병과 같은 증상을 나타내는 질병(크론병)이 사람에게서도 나타나기 시작하였다. 그러나 Map이 이러한 새로운 대장염의 원인균이며 인수공통전염병의 원인체라는 인식은 20세기 후반 이러한 질병을 앓고 있는 사람의 조직으로부터 Map을 검출할 수 있게 되고서야 나타나기 시작했다. 본 총설은 어떻게 Map이 축산분야와 사람의 공중보건 측면에서 심각한 문제를 야기시키게 되었고, Map 감염에 의한 대장염 환자의 치료가 어떻게 발전되어 왔는지 간단히 요약하고, 축산에서 Map의 통제를 위한 새로운 백신개발 전략에 대하여 소개한다.