• Title/Summary/Keyword: human population

Search Result 1,755, Processing Time 0.146 seconds

Antiproliferative Effect and Apoptotic Induction of Bauhinia forficata Extract in Human Cancer Cells. (Bauhinia forficata 추출물의 인체 암세포에 대한 성장억제 및 세포사멸 유도 활성)

  • 임혜영;이철훈
    • Microbiology and Biotechnology Letters
    • /
    • v.32 no.1
    • /
    • pp.67-71
    • /
    • 2004
  • Pata de Vaca (Bauhinia forficata) Is a tree which grows naturally in the rainforests and tropical parts of Peru and Brazil, as well as tropical zones of Asia, eastern Paraguay and northeastern Argentina. The active fraction (Pata-50) of the 70% ethanol extract from Pata de Vaca was sequentially fractionated by HP-20 Diaion column chromatography and C-18 column chromatography, and its characteristics were investigated. The growth of all cancer cells tested except for MCF-7 was Inhibited in a concentration-dependent manner by Pata-50. Its $IC_{50}$ values were estimated to be 40.4 $\mu\textrm{g}$/$m\ell$ on AGS, 51.3 $\mu\textrm{g}$/$m\ell$ on HT-29, 52.1$\mu\textrm{g}$/$m\ell$ on HepG2, 65.2$\mu\textrm{g}$/$m\ell$ on A549, and 77.5$\mu\textrm{g}$/$m\ell$ on HeLa cells. A flow cytometric analysis of HepG2 cells revealed induction of apoptosis, but cell cycle regulation was not affected. The HepG2 cell population of apoptosis region increased In a concentration-dependent manner by Pata-50.

Measurement of Oxygen Saturation Concentration by Zeolite (제올라이트별 산소포화농도 측정 실험)

  • Park, Sung-Sik;Kim, Kwang-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.19 no.2
    • /
    • pp.617-622
    • /
    • 2018
  • Air is essential for human beings to survive, but urban air is polluted with soot and harmful gases, due to the increase in industrial development and the population. Thus, air pollution in large cities is of increasing interest in the research community. One of the plausible solutions to this problem is supplying sufficient oxygen to indoor spaces. The main principle of the oxygen generator is to separate oxygen from air using synthetic zeolite. Various synthetic zeolites have been applied to public indoor spaces with the focus being placed on the oxygen exchange quality. Among the characteristics of zeolites which can be applied to oxygen generators is their ability to adsorb nitrogen from the air and, in this way, generate only oxygen. Thus, we investigated the degree of nitrogen adsorption by five kinds of natural zeolite and LTA zeolite 3A, 4A, and 5A (two different sizes). Using the PSA method, the higher the degree of nitrogen adsorption, the higher the oxygen saturation concentration, it was found that the nitrogen adsorption degree of the 5A zeolite was the highest. 6% on average. It was also found that the size of the zeolite had a significant effect on the degree of nitrogen adsorption.

Interaction Between Plants and Rhizobacteria in Phytoremediation of Heavy Metal- Contaminated Soil (중금속 오염 토양의 식물상 복원에 있어 식물과 근권세균의 상호작용)

  • Koo So-Yeon;Cho Kyung-Suk
    • Microbiology and Biotechnology Letters
    • /
    • v.34 no.2
    • /
    • pp.83-93
    • /
    • 2006
  • In heavily industrialized areas, soil sites are contaminated with high concentrations of heavy metals. These pollutants are highly accumulated to the human body through the food web and cause serious diseases. To remove heavy metals from the soil, a potential strategy is the environmental friendly and cost effective phytoremediation. For the enhancement of remediation efficiency, the symbiotic interaction between the plant and plant growth-promoting rhizobacteria (PGPR) has been attended. In this review, the interaction of the plant and PGPR in the heavy metal-contaminated soil has been reviewed. The physicochemical and biological characteristics of the rhlzosphere can influence directly or indirectly on the biomass, activity and population structure of the rhizobacteria. The root exudates are offered to the soil microbes as useful carbon sources and growth factors, so the growth and metabolism of rhizobacteria can be promoted. PGPR have many roles to lower the level of growth-inhibiting stress ethylene within the plant, and also to provide iron and phosphorus from the soil to plant, and to produce phytohormone such as indole acetic acid. The plant with PGPR can grow better in the heavy metal contaminated soil. Therefore higher efficiency of the phytoremediation will be expected by the application of the PGPR.

Secular Trend in Dietary Patterns in a Korean Adult Population, Using the 1998, 2001, and 2005 Korean National Health and Nutrition Examination Survey (우리나라 성인의 식사패턴 변화 추세 - 1998, 2001, 2005년도 국민건강영양조사자료를 이용하여 -)

  • Kang, Min-Ji;Joung, Hyo-Jee;Lim, Jeong-Hyun;Lee, Yeon-Sook;Song, Yoon-Ju
    • Journal of Nutrition and Health
    • /
    • v.44 no.2
    • /
    • pp.152-161
    • /
    • 2011
  • Koreans have undergone many changes in dietary patterns with economic growth. The purpose of this research was to examine changes in dietary patterns using data from the 1998, 2001, and 2005 Korean National Health and Nutrition Examination Survey. The study included 21,525 subjects (8,295 from 1998, 6,880 from 2001, and 6,350 from 2005) who were 20 years or older and who participated in a 24-h diet recall. The percentage energy intake from 22 food groups was calculated, and a cluster analysis was applied to identify dietary patterns. Two dietary patterns emerged; the first pattern was characterized by high intake of white rice, legumes, vegetables, kimchi, and seaweeds, the so-called "traditional" pattern (53%), whereas the other pattern was characterized by high intake of other grains, noodle dumplings, floured bread, pizza, hamburgers, cereals and snacks, potatoes, sugared sweets, nuts, fruits, meat·its products, eggs, fish, milk and dairy products, oils, beverages and seasoning, or the so-called "modified" pattern. The modified pattern comprised a higher proportion of younger aged, metropolitan residents with more education and higher incomes. However, the gender distribution was not significantly different. The modified pattern had a significantly higher intake of all nutrients except carbohydrates and had a higher proportion of energy from fat and protein. No association with a risk for metabolic syndrome was found for either dietary pattern. After age was standardized, the traditional pattern included 52% of the respondents in 1998, 54% in 2001, and 50% in 2005. However, the modified pattern was significantly more prevalent in the younger age group (20-29 yr), whereas the traditional pattern increased significantly in the older age group (${\geq}$ 65 yr). In conclusion, a secular trend was found for dietary pattern by age group, suggesting that it is necessary to monitor the changes in dietary pattern by age group and to develop appropriate dietary education and guidelines.

Association between dietary sodium intake and disease burden and mortality in Koreans between 1998 and 2016: The Korea National Health and Nutrition Examination Survey

  • Park, Clara Yongjoo;Jo, Garam;Lee, Juhee;Singh, Gitanjali M.;Lee, Jong-Tae;Shin, Min-Jeong
    • Nutrition Research and Practice
    • /
    • v.14 no.5
    • /
    • pp.501-518
    • /
    • 2020
  • BACKGROUND/OBJECTIVES: Sodium intake is positively associated with blood pressure, which may increase the risk for cardiovascular disease (CVD). Therefore, we assessed the disease burden of CVD attributable to sodium intakes above 2,000 mg/day and prospectively investigated the association between dietary/urinary sodium levels and the risk of all-cause and CVD-mortality using the Korea National Health and Nutrition Examination Survey (KNHNES). SUBJECTS/METHODS: A total of 68,578 and 33,113 participants were included for comparative risk assessment (CRA) analysis and mortality analysis, respectively, and mean follow-up time for mortality was 5.4 years. CRA analysis was used to quantify attributable incidences of stroke, ischemic heart disease (IHD), and deaths attributable to sodium intake between 1998 and 2016. Cox proportional hazard regression model was used to determine the association between sodium intake and all-cause and CVD-mortality. RESULTS: Mean dietary sodium intake decreased over time, reaching 3,647 mg/day in 2016. Similarly, the population attributable fractions of stroke and IHD, and the number of CVD-associated deaths attributable to high sodium intake/excretion also decreased. In terms of association with mortality, when participants were grouped into quartiles (Q) by energy-adjusted sodium intake, those in Q2 had a lower risk of all-cause mortality than those in Q1 with lower intakes. The risk of CVD-associated mortality was higher only in females with high sodium intake in Q4 than those in Q1. CONCLUSIONS: This nationwide data indicates that, in line with previous studies of multiple cohorts, both low and high sodium intakes may be associated with an increased risk of mortality; therefore, the optimal sodium intake for Koreans needs to be revised.

Design of Serendipity Service Based on Near Field Communication Technology (NFC 기반 세렌디피티 시스템 설계)

  • Lee, Kyoung-Jun;Hong, Sung-Woo
    • Journal of Intelligence and Information Systems
    • /
    • v.17 no.4
    • /
    • pp.293-304
    • /
    • 2011
  • The world of ubiquitous computing is one in which we will be surrounded by an ever-richer set of networked devices and services. Especially, mobile phone now becomes one of the key issues in ubiquitous computing environments. Mobile phones have been infecting our normal lives more thoroughly, and are the fastest technology in human history that has been adapted to people. In Korea, the number of mobile phones registered to the telecom company, is more than the population of the country. Last year, the numbers of mobile phone sold are many times more than the number of personal computer sold. The new advanced technology of mobile phone is now becoming the most concern on every field of technologies. The mix of wireless communication technology (wifi) and mobile phone (smart phone) has made a new world of ubiquitous computing and people can always access to the network anywhere, in high speed, and easily. In such a world, people cannot expect to have available to us specific applications that allow them to accomplish every conceivable combination of information that they might wish. They are willing to have information they want at easy way, and fast way, compared to the world we had before, where we had to have a desktop, cable connection, limited application, and limited speed to achieve what they want. Instead, now people can believe that many of their interactions will be through highly generic tools that allow end-user discovery, configuration, interconnection, and control of the devices around them. Serendipity is an application of the architecture that will help people to solve a concern of achieving their information. The word 'serendipity', introduced to scientific fields in eighteenth century, is the meaning of making new discoveries by accidents and sagacity. By combining to the field of ubiquitous computing and smart phone, it will change the way of achieving the information. Serendipity may enable professional practitioners to function more effectively in the unpredictable, dynamic environment that informs the reality of information seeking. This paper designs the Serendipity Service based on NFC (Near Field Communication) technology. When users of NFC smart phone get information and services by touching the NFC tags, serendipity service will be core services which will give an unexpected but valuable finding. This paper proposes the architecture, scenario and the interface of serendipity service using tag touch data, serendipity cases, serendipity rule base and user profile.

Estimation of Dietary Daily Intake of PCDDs/PCDFs from Korean Retail Food (우리 나라 시판 식품을 통한 다이옥신 섭취량 평가)

  • Kim, Kyoung-Sim;Kim, Jong-Guk;Kim, Man-Young
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.22 no.7
    • /
    • pp.1345-1355
    • /
    • 2000
  • The main route of exposure of the human population to polychlorinated dibenzop-dioxins(PCDDs) and polychlorinated dibenzofurans(PCDFs) is through the diet. However in Korea, there are few studies on PCDDs/PCDFs levels in environmental samples and foods. The purpose of this study is to analyze concentration of PCDDs/PCDFs in Korean retail foods and to estimate dietary daily intake of them. 9 samples from animal food and 10 samples from plant food were analysed for PCDDs/PCDFs. Concentrations of PCDDs/PCDFs ranged from 0.02(milk) to 5.39(anchovy)pg/g. TEQ levels appeared in order of fish/shellfish, meat, vegetable, cereal, fruit and milk, and these values ranged from 0.0008 to 0.3153pgTEQ/g. The daily intake of PCDDs/PCDFs via food was calculated to be about 37.7pgTEQ/day and these values are equivalent to 0.75 pgTEQ/kg b.w./day, under consideration of 50kg for body weight. The daily intake of PCDDs/PCDFs via food was lower than that in other countries. From these results, it is important to note that fish/shellfish intake is one of the main sources of PCDDs/PCDFs exposure in Korea.

  • PDF

The Effects of Pollutants into Sub-basin on the Water Quality and Loading of Receiving Streams (하천 수질 및 부하량에 미치는 유역 내 오염원의 영향)

  • Han, Mideok;Son, Jeeyoung;Ryu, Jichul;Ahn, Kihong;Kim, Yongseok
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.36 no.9
    • /
    • pp.648-658
    • /
    • 2014
  • We examined the effects of pollutants into sub-basin on the water quality and loading based on data surveyed during January-December 2013 from 13 sites of 5 streams in the Jinwi watershed. We used the contour plot and Kruskal-Wallis rank sum test to analyze seasonal variation of water quality and loading and Pearson correlation analysis to assess the relationships between pollutants and loadings. The significantly higher seasonal variation were SS, TN and TOC as compared to other water quality constituents (P < 0.001). A significant interaction existed between the effects of human population and the effects of discharge of Sewage Treatment Plant (STP) on water quality and loading, especially for the spring and winter seasons. It is necessary to control discharge water of sewage and wastewater from industrial facilities and to make full use of the watershed management system such as TMDLs in operation since 2012 for improvement in stream water quality.

Water Quality Improvement Plans based on the Analysis of Pollutant Discharge Characteristics and Water Quality Modelling of Seokmun Reservoir Watershed (석문호 유역 오염물질 배출특성 분석 및 수질모델링에 기초한 수질개선방안 연구)

  • Choi, Moojin;Jung, Woohyeuk;Choi, Jaehun;Kim, Youngil
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.39 no.10
    • /
    • pp.581-590
    • /
    • 2017
  • For effective improvement of water quality in Seokmun reservoir, this study implemented various analyses including the tributary water quality and flowrate monitoring, contamination of sediment, investigation of pollution source, selection of priority management target tributary by stream grouping method. The COD concentration of the majority of tributaries in Seokmun reservoir watershed was relatively higher than BOD concentration. The concentration of water pollutants regardless of water quality parameters in Yeokcheon, Dangjincheon, Sigokcheon, Baekseokcheon, small stream in Jinkwanri and Janghangri were higher than the other tributaries. The pollution sources in the Seokmun reservoir watershed were mostly distributed in the population, livestock, and industry. The pollutants, which located in Yeokcheon, Dangjincheon, Baekseokcheon, and small stream in Janghangri selected as priority management target tributary, should be preferentially reduced for improving the water quality in Seokmun reservoir. As the evaluation results of water quality in Seokmun reservoir for the effect of water quality improvement according to various scenarios using water quality model, it was found that the water quality in Seokmun reservoir due to the construction of a wastewater treatment plant for management of pollutants in the watershed would be satisfied the class V of water environment standard in reservoir.

Inclusive Impact Index "Triple I" for Assessing Ocean Utilization Technologies (해양이용기술 평가를 위한 포괄적 영향지수 "트리플 I")

  • Otsuka, Koji
    • Journal of the Korean Society for Marine Environment & Energy
    • /
    • v.15 no.2
    • /
    • pp.118-125
    • /
    • 2012
  • World population has increased rapidly following the industrial revolution, reaching 7 billion in 2012. Several forecasts estimate that this number will rise to about 8 billion in 2025. Improvements of living standards in developing nations have also raised resource and energy demands worldwide. In consequences, human beings have faced many global and urgent problems, such as global warming, water and food shortages, resource and energy crises, and so on. Many ocean utilization technologies for avoiding or reducing such big problems have been developed, for examples $CO_2$ ocean sequestration, seawater desalination, artificial upwelling, deepwater mining, and ocean energies. It is important, however, to assess such technologies from the viewpoints of sustainability and public acceptancy, since the aims of those technologies are to develop sustainable social systems rather than conventional ones based on fossil resources. Inclusive Marine Pressure Assessment and Classification Technology Research Committee (generally called IMPACT Research Committee) of Japan Society of Naval Architects and Ocean Engineers, has proposed Inclusive Impact Index "Triple I" as an indicator, which can predict both environmental sustainability and economical feasibility, in order to assess the ocean utilization technologies from the viewpoints of sustainability and public acceptancy. This index was considered by combining Ecological Footprint and Environmental Risk Assessment. The Ecological Footprint and the Environmental Risk Assessment are introduced in the first part of this paper. Then the concept and the structure of the Triple I are explained in the second part of this paper. Finally, the economy-ecology conversion factor in Triple I accounting is considered.