• 대한지역사회영양학회지
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• 제12권3호
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• pp.223-234
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• 2007

This study was done to determine the trans fatty acid (tFA) composition of human milk from postpartum to sixth months after delivery, to investigate the tFA intake of lactating women, and to estimate the intakes of tFA by infants exclusively fed breast milk. A total of 27 lactating Korean women participated to this study voluntarily, gave their breast milk, and responded to an investigation of their diets. The lactating women consumed 2.3-2.8 g/d of tFAs over the period of the first, second, third, and sixth months postpartum, which was 3.4-4.9% of the total fat intake and 0.8%-1.2% of the total energy intake. The proportions of tFAs in the breast milk were 1.89% in colostrum, 1.78% in transitional milk, and 1.78-2.25 in mature milk of the first, second, third, and sixth months postpartum. The tFAs of the breast milk identified in this study were C16:1n9t, C18:1n9t, C18:2n6t12t, C18:2n6t12c, C18:2n6t12t and C18:2n6t11t. Among them, C18:1n9t was predominant, which made up 59.26% of all tFAs in cob strum, 62.36% in transitional milk, and 64.42% in mature milk. The proportion of total tFA was unchanged with time, although some significant differences were noted for individual tFAs. The percentages of C18:2n6t12c and C18:2n6c12t decreased over the study period. Estimated tFA intake of the exclusively breast-fed infants was 0.18 g/d when fed colostrum, 0.29 g/d when fed transitional milk, and 0.53 g/d when fed mature milk until the sixth month of postpartum. Those were 0.5%, 0.8%, and 1.1% of the total energy intake. The results in this study indicate that lactating Korean women consume not a large quantity of tFAs, secrete breast milk not containing much tFA, and the estimated intake of tFAs by infants fed exclusively breast milk is not great.

• Journal of Nutrition and Health
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• 제26권8호
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• pp.967-973
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• 1993

The longitudianl study on taurine intake of breast-fed infants from Korean lacto-ovo-vegetarian (n=23) and non-vegetarian(n=22) at 3-5, 15, 30, 60, 90, 120, 150 days postpartum was performed. The taurine content of human milk was analyzed by amino acid autoanalyzer (LKB-Alpha plus) and the human milk intak of infants was measured by test weighing method. The mean taurine content of human milk at each postpartum period was 434$\pm$128.362$\pm$, 304$\pm$90, 306$\pm$90, 302$\pm$77, 310$\pm$108, 248$\pm$53 nmol per ml in non-vegetarian and 418$\pm$112, 380$\pm$97, 314$\pm$97, 262$\pm$83, 206$\pm$79, 176$\pm$55, 153$\pm$31 nmol per ml in lacto-ovo-vegetarian, respectively. The content decreased significantly during lactation(p<0.05). The mean tauring intake at 15, 30, 60, 90, 120, 150 days postpartum was 195$\pm$94, 202$\pm$74, 212$\pm$54, 177$\pm$43, 137$\pm$47, 132$\pm$35, 106$\pm$15 umol per day in infants of lacto-ovo-vegetarian. Thu taurine content in human milk and the taurine intake of infants were different during lactation between non-vegetarian and lacto-ovo-vegetarian, and the intake per kg body weight during lactaion decreased.

• Nutrition Research and Practice
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• 제5권1호
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• pp.46-51
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• 2011

To evaluate the effect of feeding methods on growth and zinc nutritional status of infants early in life, we monitored from birth to 36 months in 51 infants who were exclusively fed human milk (HM, n=20), casein-based formula (CBF, n=12), or soy-based formula (SBF, n=19) during the first five months of life. Zinc status was assessed by analyzing serum zinc concentrations and zinc intakes. Zinc contents in HM and formulas were measured. Zinc intake was estimated by weighing infants before and after feeding in the HM group and by collecting formula-intake records in the CBF and SBF groups. After solid foods were introduced, all foods consumed were also included to estimate zinc intake. The growth of infants in all groups was similar to that established for normal Korean infants. Human milk zinc concentrations declined as lactation progressed. Zinc concentrations in all formulas tested in this study were higher than HM and were also higher than those claimed by the manufacturers. During the first twelve months, mean serum zinc concentrations of infants were similar in all groups, although infants in the HM group consistently had the lowest zinc intake among the groups, and the overall zinc intake in infants fed SBF was highest. This finding could be explained by the difference zinc bioavailability of HM and formulas. In conclusion, infants fed HM, CBF or SBF has normal growth up to three years of age, although HM contained the lowest zinc concentration followed by CBF, then SBF.

• Journal of Nutrition and Health
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• 제29권8호
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• pp.908-915
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• 1996

Protein concentration in human from 39 well-norished American women and its adequacy for growth of exclusively breastfed infants(BF) and breastfed infants fed supplementary foods(BFS)from 1-6 months postpartum were studied. Mean protein concentration of breast milk measured by Lowry et al., using human serum albumin as a standard, over the first 6 months lactation was 1.31$\pm$0.13g/dl. Concentration of protein was singnificantly higher at the first month of lactation (1.55$\pm$0.23g/dl)(P<0.05) than any other month studied. Mean volume of breast milk ranged from 662-848ml/day in the BE group and from 415-661ml/day in the BFS group during the first 6 months of lactation. Mean protein intake of infants ranged from 1.3-2.2g/kg in the BF group and from 1.4-2.1g/kg in the BFS group. Mean protein intake (g/kg body weight) of both BF and BFS groups was less than Recmmended Dietary Allowance(1989, USA) of 2.2g/kg except at 1 month of age. However, mean growth of the infants was normal according to NCHS reference, suggesting that the RDA for protein was unrealistically high for infants during 2-6 months of age. Protein provided by breast milk alone appeared adequate for normal growth during this time.

• Journal of Nutrition and Health
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• 제26권6호
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• pp.772-782
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• 1993

한국인 수유부 29명에 대하여 분만 후 1주부터 12주까지 5회에 걸쳐서 조사한 식이 섭취량과 같은 기간에 이들로부터 채유한 모든 시료에서 무기질과 미량원소의 함량을 측정하였다. 또한 얻어진 자료량과의 관계 및 모유내 각 무기질 농도 사이의 상관성을 비교 분석하였다. 본 연구 대상인 수유부들의 영양섭취 정도는 개인에 따른 차이가 컸으며 하루 평균 영양소 섭취량은 모든 한국 수유부에 대한 영양 권장량에 미달되었다. 성숙유에서 분석된 무기질과 미량원소의 농도분포도 넓었으며 칼슘과 마그네슘의 농도가 다른 연구 결과보다 다소 높은 경향이었고, 망간의 몰리브덴을 제외한 다른 미량원소의 함량은 여러나라에서 보고한 농도 범위에 포함되었다. 수유뷰의 열량 섭취량은 모유의 나트륨 농도와 음의 상관성이 있었으며 단백실 섭취량과 유즙의 아연 및 구리 함량은 양의 상관성을 나타내었고 몰르브덴 농도와는 음의 상관 관계가 있었다. 칼슘 섭취량은 모유의 마그네슘 농도에 영향을 주었으며 인의 섭취는 유즙내 니켈 함량에 영향을 주었다. 비타민 C섭취량은 모유의 철분 함량에 영향을 주지 않았으며 구리와는 음의 상관성이 나타났다. 모유의 5가지 무기질과, 6가지 미량원소에 대한 각각의 농도 사이에서 아래와 같이 17쌍은 p<0.05 수준에서 유의성있는 양의 상관성 보여주었다. 즉, 나트륨 농도와는 칼륨과 철분 ; 칼륨 농도와는 칼슘, 인, 마그네슘, 철분, 구리, 망간, ; 칼슘 농도와는 마그네슘, 철분, 망간, 몰리브덴, 니켈; 마그네슘 농도와는 철분, 몰리브덴 ; 철분 농도와는 아연; 끝으로 니켈 농도와 망간 사이에 상관성이 나타났다.

• 분석과학
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• 제35권1호
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• pp.8-14
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• 2022

Many studies have shown that advanced glycation end-products (AGEs) and glycation adducts are significantly linked to aging and disease. Particularly, the level of glycation in human milk is important because the AGE intake is closely related to AGE levels in infants. In this study, we used human milk samples obtained from four primiparae and four multiparae. We isolated proteins using acetone and trichloroacetic acid (TCA) precipitation. A total of 67 glycated proteins and 122 glycated peptides was quantified; among them, 19 glycated peptides were differentially expressed. We confirmed that the degree of glycation differed according to fertility. The study provides a foundation for using proteomics to evaluate the mother's milk quality and link between maternal health and human milk quality.

• 한국생활과학회지
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• 제12권2호
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• pp.265-273
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• 2003

The aim of this study was to investigate the effect d concentrated fermented milk on the improvement of defecation in female students with constipation. This yogurt was fermented with Bifidobacterium, L. acidophilus, and S. thermophilus and supplemented with oligosaccharides, dietary fiber, and yeast and mushroom extracts. 44 female students with constipation were sampled as subjects and fed 150ml fermented milk per day for 2 weeks period. After each defecation, the subjects were examined for the status of stool evacuation by questionnaires. The frequency of stool evacuation, fecal amount, time spending for evacuation, fecal color and shape, and refreshing feeling after evacuation were remarkably improved after ingestion of fermented milk for 2 weeks. These effects were greater in the heavy constipation group than in the mild group. The fecal odor did rot decrease significantly after 2 weeks of intake of fermented milk, but the odor thended to decrease after the intake of fermented milk These results indicated that the ingestion of concentrated fermented milk is effective to improve the constipation.

• 대한지역사회영양학회지
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• 제4권1호
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• pp.30-36
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• 1999

This study was carried out to longitudinally investigate the iron and zinc intakes and correlation with growth performance of 25 male breast-and formula-fed infants from 1 to 3 months postpartum, longitudinally. There were four groups breast fed(BF) and three formula fed groups((FFM, FFN and FFP). Milk intakes and the concentration of iron and zinc from human milk and the formulas were measured. The iron content of human milk was $2.07\pm{1.05(0.63~5.65)}\mu{g}$/ml. The zinc content was $2.43\pm{1.14(0.70~5.30)}\mu{/ml.}$ Both were not significantly different among postpartum months. The average iron intake of the breast-fed and formula-fed infants was $1.6\pm{0.7mg/}$day and $8.4\pm{2.3mg}$/day, respectively. The iron intake of breast-fed infants was higher than previous reports. And that of formula-fed infants was higher than the RDA. The average zinc intake of the breast-fed group was $1.9\pm{0.9mg/}$day and formula-fed infants' was $2.7\pm{0.7mg/}$day, which was higher than the RDA. There was no correlation between these mineral intakes and the growth performance during 1 to 3 postpartum months. So, extensive studies of the iron content of human milk and wide cross-sectional studies for establishing iron and zinc recommended dietary allowances for infants are needed.

• Journal of Nutrition and Health
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• 제24권3호
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• pp.219-229
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• 1991

The longitudinal changes on human milk volume per day and lactational performance of 23 Korean lacto-ovo-vegetarians(primiparae=11, multiparae=12) from 0.5 to 5 months after parturition have been studied by test weighing method. The human milk volume per day tended to increase during lactation. The mean volume (SD, ml/day) at 0.5, 1, 2, 3, 4, 5 months were 502(102), 692(127), 697(100), 684( 125), 757(52), 703(70), respectively. The overall mean volume was 661$\pm$132ml/day. The peak milk volume during the lactation was observed at most lactating women at the 1st month. The distributions of the individual mean volume during the first 5 months of lactation were found over 750m1(8.7% ), 650-750ml(47.9% ), 550-650m1(2l.7% ), and 450-550ml(2l.7% ) The number of feeding per day was 8.1 ($\pm$1.0) at 0.5 months postpartum, which was consistently decreased. However, the mean volume per feeding was increased from 62($\pm$9.5)ml at 0.5 month to 112($\pm$13.3)ml at 5 months postpartum. The milk volume was correlated with the peak volume. and maternal age. but not with weight before delivery. maternal height and birth weight. No differences of milk volume and lactational performance between facto-ovo-vegetarian and nonvegetarian women were observed. This study suggests that the human milk volume cited in the recommended dietary allowances for Koreitns is over estimated.

• Journal of Nutrition and Health
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• 제28권7호
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• pp.620-628
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• 1995

This study investigated micro-mineral content in human milk along with nutritional intake of lactating women. Milk samples were collected from 33 healthy lactating women and mineral levels were analyzed. Copper, zinc, manganese and selenium were analyzed. The factors that affect the mineral levels in human milk were also investigated longitudinally from 2-5 days to 12 weeks postpartum. Concentrations of manganese and selenium didn't differ significantly within the lactation period. the levels of copper and zinc declined linearly over the first 12 weeks of lactation. Statistically significant quadratic trends were observed in zinc concentrations. There was no significant correlation between maternal age and mineral concentrations throughout the lactation period. In addition, no significant differences were found between the primipara and the multipara for mineral concentrations in human milk.