• Title/Summary/Keyword: human immunodeficiency virus/AIDS

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Orthognathic surgery of human immunodeficiency virus infected patient : A case report (Human immunodeficiency virus에 감염된 환자의 악교정수술 : 증례보고)

  • Lee, Jin-Sook;Choi, Won-Cheul;Yun, Kyoung-In
    • The Journal of the Korean dental association
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    • v.51 no.8
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    • pp.451-458
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    • 2013
  • Human immunodeficiency virus is a retrovirus that causes acquired immunodeficiency syndrome. Acquired immunodeficiency syndrome is defined in terms of "either the occurrence of specific diseases in association with a HIV infection or a CD4 cell count below 200cells/ul" by centers for disease control and prevention(CDC). When performing the surgery of human immunodeficiency virus infected patients, several factors should be considered. First, standard precautions should be performed to prevent infection. It is safe to treat human immunodeficiency virus infected patients if we follow the standard precautions. Second, when making a surgical plan, surgeons have to take account of delayed bone healing and postsurgical infection. This case report presents a case of orthognathic surgery of human immunodeficiency virus infected patient.

A Case of Deep Neck Infection by Tuberculosis in AIDS (AIDS환자에서 발생한 결핵성 심경부감염 1례)

  • Moon Jun Hwan;Choi Ho Young;Lee Deung Ho;Jun Sung Hwan
    • Korean Journal of Bronchoesophagology
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    • v.11 no.1
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    • pp.37-41
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    • 2005
  • Deep neck infections mean infection in the potential spaces and facial planes of the neck, either abscess formation or cellulitis. Deep neck infections are caused by dental, salivary gland, pharyngeal and tonsillar infections. Sometimes, deep neck infection may be caused by tuberculosis in case of immunodefiecient patients. Acquired immunodeficiency syndrome(AIDS) is a disease associated with defective cell-mediated immunity after infected with human immunodeficiency virus(HIV). The chance of opportunistic infection in patients of AIDS increases as the level of immunodeficienty progresses. Human immunodeficiency virus infection is the most single significant risk factor for progression of pulmonary tuberculosis to extrapulmonary sites. In patients infected with HIV, the rate of extrapulomonary tuberculosis rises upto $60\%$. We report a case of a 47 year old male patient with AIDS associated with deep neck infection by tuberculosis.

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Prevention of Murine Acquired Immunodeficiency Syndrome (MAIDS) Development by Oriental Herb Extracts

  • Yang, Yun-Hee;Yang, Joo-Sung
    • Journal of Applied Biological Chemistry
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    • v.48 no.4
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    • pp.170-177
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    • 2005
  • Oriental medicinal herb extracts (OHE) showing anticancer activities were investigated for effectiveness as antiviral drugs. Infection of MuLV to cell line resulted in formation of giant syncytia. Number of giant syncytia in culture treated with OHE decreased by 40% compared to that of non-OHE-treated cell culture. To determine OHE effects on progeny release, RT-PCR was performed. In vivo animal studies demonstrated effectiveness of OHE as antiviral drug when administered orally. After OHE administration, viral cytopathic effects decreased. Infected mice showed splenomegaly and over-proliferation of lymphocytes with decreased CD4+ cell counts. These symptoms decreased in OHE-treated mice, indicating OHE maybe useful therapeutics against MuLV/MAIDS as Human Immunodeficiency Virus (HIV)/AIDS animal model. Results show XC plaque assay and in vivo MAIDS model using MuLV are suitable tools for screening anti-retroviral drug candidates.

Introduction of Phylodynamics for Controlling the HIV/AIDS Epidemic in Korea

  • Bae, Jong-Myon
    • Journal of Preventive Medicine and Public Health
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    • v.51 no.6
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    • pp.326-328
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    • 2018
  • As over 1000 new cases of HIV/AIDS occur in Korea annually, preventive health programs against HIV/AIDS are urgently needed. Since phylodynamic studies have been suggested as a way to understand how infectious diseases are transmitted and evolve, phylodynamic inferences can be a useful tool for HIV/AIDS research. In particular, phylodynamic models are helpful for dating the origins of an epidemic and estimating its basic reproduction number. Thus, the introduction of phylodynamics would be a highly valuable step towards controlling the HIV/AIDS epidemic in Korea.

Food Security in Households of People Living With Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome: A Cross-sectional Study in a Subdivision of Darjeeling District, West Bengal

  • Dasgupta, Pallabi;Bhattacherjee, Sharmistha;Das, Dilip Kumar
    • Journal of Preventive Medicine and Public Health
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    • v.49 no.4
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    • pp.240-248
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    • 2016
  • Objectives: Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) adversely impacts food security in households of people living with HIV/AIDS (PLWHA). Little research has focused on food insecurity among PLWHA in India. The purpose of this study was to identify the prevalence of and factors relating to food security in households of PLWHA in the Siliguri subdivision of Darjeeling, West Bengal, India. Methods: A cross-sectional community-based study was carried out among 173 PLWHA residing in Siliguri and registered at the Anti-retroviral Therapy Centre of North Bengal Medical College & Hospital. Data was collected at the household level with interviews of PLWHA using a food security survey instrument. We analyzed the associations using logistic regression. Results: The prevalence of household food security among the participants was 50.9% (88/173). Five years or more of schooling, higher socioeconomic class and males were found to be significantly associated with a higher likelihood of food security. A later stage of the disease and the presence of other family members with HIV/AIDS were significantly associated with a lower likelihood of food security. The major coping strategies to deal with food insecurity in the acute phase HIV infection included borrowing money (56.1%), followed by spousal support, loans from microfinance institutions, banks, or money lenders, borrowing food, or selling agricultural products. Conclusions: The present study revealed that only about half of households with PLWHA were food secure. Prior interventions relating to periods of food and economic crisis as well as strategies for sustaining food security and economic status are needed in this area.

Epidemiology of AIDS (AIDS의 역학)

  • 김정순
    • Korean Journal of Health Education and Promotion
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    • v.5 no.1
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    • pp.6-11
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    • 1988
  • AIDS, 즉 후천성면역결핍증은 인간면역결핍바이러스(Human Immunodeficiency Virus : HIV)라고 불리우는 바이러스에 의한 인간면역체계의 붕괴로 발생하는 질환이다. 1979년 최초로 새로운 임상적특징을 가진 증후군으로 의학학술지에 발표되어 의료계의 주목을 끌어오다가 1981년 봄 로스앤절레스에 있는 남성동성연애자에게 발생한 AIDS의 첫 예가 보고되어 본격적 연구가 시작되었다.

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Knowledge and attitudes of Korean dentists towards human immunodeficiency virus/acquired immune deficiency syndrome

  • Park, Jung-Chul;Choi, Seong-Ho;Kim, Yong-Tae;Kim, Sun-Jong;Kang, Hee-Jung;Lee, Jong-Ho;Shin, Seung-Chul;Cha, Young-Joo
    • Journal of Periodontal and Implant Science
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    • v.41 no.1
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    • pp.3-9
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    • 2011
  • Purpose: Infection with human immunodeficiency virus (HIV) remains a major global threat, and although the prevalence is comparatively still very low, the number of HIV-positive Koreans is increasing. However, there are no official guidelines as to how to treat people living with HIV/acquired immunodeficiency syndrome (AIDS) (PLWHA) or how to screen for potentially infectious people. This study assessed the level of knowledge and attitudes of dentists in Korea toward PLWHA, and their attitudes to screening patients for HIV infections. Methods: A cross-sectional prospective survey targeting dentists working in Korea was conducted using a self-administered questionnaire. Results: A satisfactory level of knowledge about HIV/AIDS and a relatively positive attitude toward PLWHA was found. Most of the respondents preferred rapid HIV testing using oral fluid as a specimen. The general attitude of dentists toward HIV/AIDS is sufficiently positive to enable provision of the best treatment to the patients in need. Conclusions: Most of the dentists require HIV testing in dental clinics. In spite of their needs, there are several obstacles. It is hoped that financial considerations and official legal requirements related to HIV testing strategies will be considered.

Inhibitory Activities of Korean Plants on HIV-1 Protease

  • Min, Byung-Sun;Bae, Ki-Hwan;Kim, Young-Ho;Shimotohno, Kunitada;Miyashiro, Hirotsugu;Hattori, Masao
    • Natural Product Sciences
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    • v.4 no.4
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    • pp.241-244
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    • 1998
  • For the development of anti-AIDS agents, thirty-seven methanol extracts of Korean plant materials were tested for their inhibitory effects on human immunodeficiency virus type-1 (HIV-1) protease. Extracts of seven plants showed more than 30% inhibitory activities on HIV-1 protease at a concentration of $100\;{\mu}g/ml$. The bark of Berchemia berchemiaefolia, the leaf of Lindera erythrocarpa and the whole plant of Siegesbeckia pubescens exhibited significant inhibititory activities on HIV-1 protease with 56.2, 50.8, and 46.6%, respectively.

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A Spirulina maxima-derived peptide inhibits HIV-1 infection in a human T cell line MT4

  • Jang, In-Seung;Park, Sun Joo
    • Fisheries and Aquatic Sciences
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    • v.19 no.9
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    • pp.37.1-37.5
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    • 2016
  • Human immunodeficiency virus (HIV) is the causative agent of acquired immune deficiency syndrome (AIDS). Anti-HIV agents targeting various steps in HIV life cycle have been developed; however, so far, no effective drugs have been found. We show here that a peptide isolated from Spirulina maxima (SM-peptide) inhibits HIV-1 infection in a human T cell line MT4. SM-peptide inhibited $HIV-1_{IIIB}$-induced cell lysis with a half-maximal inhibitory concentration ($IC_{50}$) of 0.691 mM, while its 50 % cytotoxic concentration ($CC_{50}$) was greater than 1.457 mM. Furthermore, the SM-peptide inhibited the HIV-1 reverse transcriptase activity and p24 antigen production. This suggests that SM-peptide is a novel candidate peptide, which may be developed as a therapeutic agent for acquired immunodeficiency syndrome patients.