• 제목/요약/키워드: human health risk assessment

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Stabilization of fluorine in soil using calcium hydroxide and its potential human health risk

  • Jeong, Seulki;Kim, Doyoung;Yoon, Hye-On
    • Environmental Engineering Research
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    • 제24권4호
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    • pp.654-661
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    • 2019
  • This study assessed the stabilization of fluorine (F)-contaminated soil using calcium hydroxide (Ca(OH)2) and the consequent changes in human health risk. The bioavailable F decreased to 3.5%, (i.e., 57.9 ± 1.27 mg/kg in 6% Ca(OH)2-treated soil sample) from 43.0%, (i.e., 711 ± 23.4 mg/kg in control soil sample). This resulted from the conversion of water-soluble F to stable calcium fluoride, which was confirmed by XRD spectrometry. Soil ingestion, inhalation of fugitive dust from soil, and water ingestion were selected as exposure pathways for human health risk assessment. Non-carcinogenic risks of F in soils reduced to less than 1.0 after stabilization, ranging from 4.2 to 0.34 for child and from 3.0 to 0.25 for adult. Contaminated water ingestion owing to the leaching of F from soil to groundwater was considered as a major exposure pathway. The risks through soil ingestion and inhalation of fugitive dust from soil were insignificant both before and after stabilization, although F concentration exceeded the Korean soil regulatory level before stabilization. Our data suggested that substantial risk to human health owing to various potential exposure pathways could be addressed by managing F present in soil.

국내 도로 노면 퇴적입자 내 PAHs의 인체 위해성 평가 (Human Health Risk Assessment of Polycyclic Aromatic Hydrocarbons (PAHs) from Road Dust Sediments in Korea)

  • 이가인;김홍경;지승민;장용철
    • 환경영향평가
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    • 제29권4호
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    • pp.286-297
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    • 2020
  • 본 연구에서는 국내 4개 도시(6개 지점)로부터 도로 노면 퇴적입자 내 PAHs의 농도 및 분포특성을 비교, 분석하고 오염 수준에 대한 초과 발암 위해도를 산정하여 인체 위해성 평가를 수행하였다. 지역별 오염농도를 바탕으로 흡입, 섭취, 피부 노출에 대한 노출경로를 설정하여 결정론적 위해성평가를 수행한 결과, 울산 지역의 경우 위해도 발암 기준 1×10-6을 상회하는 결과가 나타났다. 또한 발암위해도가 있다고 판단되는 해당 지역에 대한 확률론적 위해성평가 결과, 확률적 평균값이 단일값을 활용한 결정론적 위해도 산정에서 도출되었던 발암위해도와 중앙값에 근접한 수준을 나타내었다. 민감도 분석 결과, 노출시간에 따른 기여도가 가장 크게 나타났다. 향후 기준치를 초과하는 발암 위해도를 나타내는 지역에 대한 위해도 관리는 물론 상세한 모니터링을 통한 추가 위해성 평가가 이루어져야 할 것으로 판단되며, 지역적 특성을 반영한 노출계수의 산정을 통해 인체 위해도 평가 결과 신뢰도를 높여야 할 것으로 사료된다.

Non-chemical Risk Assessment for Lifting and Low Back Pain Based on Bayesian Threshold Models

  • Pandalai, Sudha P.;Wheeler, Matthew W.;Lu, Ming-Lun
    • Safety and Health at Work
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    • 제8권2호
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    • pp.206-211
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    • 2017
  • Background: Self-reported low back pain (LBP) has been evaluated in relation to material handling lifting tasks, but little research has focused on relating quantifiable stressors to LBP at the individual level. The National Institute for Occupational Safety and Health (NIOSH) Composite Lifting Index (CLI) has been used to quantify stressors for lifting tasks. A chemical exposure can be readily used as an exposure metric or stressor for chemical risk assessment (RA). Defining and quantifying lifting nonchemical stressors and related adverse responses is more difficult. Stressor-response models appropriate for CLI and LBP associations do not easily fit in common chemical RA modeling techniques (e.g., Benchmark Dose methods), so different approaches were tried. Methods: This work used prospective data from 138 manufacturing workers to consider the linkage of the occupational stressor of material lifting to LBP. The final model used a Bayesian random threshold approach to estimate the probability of an increase in LBP as a threshold step function. Results: Using maximal and mean CLI values, a significant increase in the probability of LBP for values above 1.5 was found. Conclusion: A risk of LBP associated with CLI values > 1.5 existed in this worker population. The relevance for other populations requires further study.

생태수질기준설정을 위한 대상물질의 생태위해성 평가 (Ecological Risk Assessment of Chemicals of Concern for Initiation of Ecorisk-based Water Quality Standards in Korea)

  • 안윤주;남선화;김용화
    • 한국물환경학회지
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    • 제24권5호
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    • pp.592-597
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    • 2008
  • Current water quality standard (WQS) in Korea is based on the protection of human health, not considering the protection of aquatic organisms. Most of chemicals can be toxic to ecological biota as well as human. Health of aquatic biota is closely related to the human health via food chain, therefore ecological risk based-WQS needs to be developed to protect the aquatic ecosystem. In this study, we selected the 31 chemicals in the Project entitled 'Development of integrated methodology for evaluation of water environment'. The methodology for calculating water quality criteria was derived from the Australian and New Zealand processes for deriving guideline trigger value for aquatic ecosystem. The available ecotoxicity data were collected from US EPA's ECOTOXicology Database (ECOTOX), TOX-2000 Database, European Chemicals Bureau (ECB)'s International Uniform Chemical Information Database (IUCLID) and Environmental Protection Agency (US EPA)'s report 'Ambient Water Quality Criteria (AWQC)'. The aquatic toxicity data for the Korean species were selected for risk assessment to reflect the Korean water environment. The monitoring values were calculated from the water quality monitoring data four main Korean rivers. We suggested the order of priorities of chemicals based on ecological risk assessment. We expect that these results can be useful information for establishing the WQS for the protection of aquatic ecosystem.

대기환경부문 건강위해평가의 국내 연구 동향과 발전방향 (The Domestic Research Trend and the Road Map of Health Risk Assessment of the Air Quality in Korea)

  • 신동천
    • 한국대기환경학회지
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    • 제29권5호
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    • pp.528-535
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    • 2013
  • Air pollution in large cities is reduced through the environmental health policies, but due to increased population and automobile, some pollutants are still a problem. These air pollutants are known to cause asthma and respiratory diseases. According to an OECD report, the number of premature deaths will increase. Hazardous air pollutants should be managed through a systematic monitoring, risk assessment, and many studies are in progress. In order to manage hazardous air pollutants, transformation of policy for the protection of human health is required. management policy through the calculation of the excess number of deaths that occur from hazardous air pollutants for the public health is necessary. Korea has put a lot of efforts for air quality, but health risk assessment should be more considered.

환경영향평가에 있어서 건강위해성평가 기법의 활용방안에 관한 연구 (A Developmental Methodology of Environmental Impact Assessment: Application of Health Risk Assessment)

  • 구자건;정용
    • 환경영향평가
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    • 제1권1호
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    • pp.51-59
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    • 1992
  • Environmental Impact Assessment(EIA) is defined as an activity designed to identify and predict the impact on the environment. In the process of an EIA, the quantitative evaluation is generally performed for the air and water quality which have the national environmental quality standards. But the predicted values for the air and water quality are simply compared to the environmental standards. At present, the EIA process of Korea has no consideration for the possible human health risk resulting from the development projects. Environmental Health Impact Assessment(EHIA) is an applied methodology of EIA to estimate the acceptable health risk caused by a specified level of environmental pollutants. Estimating the excessive lifetime risk that is a possibility of dying of a certain disease by environmental contaminants, is useful as an evaluation technique of EHIA. It is recommanded the decision-makers to make efficient use of EHIA not only the development projects but also legislative proposals, policies and programmes in future.

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Human Health Risk Assessment of Trichloroethylene from Industrial Complex A

  • Sin, Sae-Mi;Byeon, Sang-Hoon
    • Toxicological Research
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    • 제28권3호
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    • pp.173-178
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    • 2012
  • This study investigated the human health risks of trichloroethylene from Industrial Complex A. The excessive carcinogenic risks for central tendency exposure were $1.40{\times}10^{-5}$ for male and female residents in the vicinity of Industrial Complex A. The excessive cancers risk for reasonable maximum exposure were $2.88{\times}10^{-5}$ and $1.97{\times}10^{-5}$ for males and females, respectively. These values indicate that there are potential cancer risks for exposure to these concentrations. The hazard index for central tendency exposure to trichloroethylene was 1.71 for male and female residents. The hazard indexes for reasonable maximum exposure were 3.27 and 2.41 for males and females, respectively. These values were over one, which is equivalent to the threshold value. This result showed that adverse cancer and non-cancer health effects may occur and that some risk management of trichloroethylene from Industrial Complex A was needed.

음용수중 휘발성 유기오염물질의 노출경로에 따른 위해도 추정치 비교연구 (A Study on Comparison of Risk Estimates Among Various Exposure Scenario of Several Volatile Organic Compounds in Tap Water)

  • 정용;신동천;김종만;양지연;박성은
    • Environmental Analysis Health and Toxicology
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    • 제10권1_2호
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    • pp.21-35
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    • 1995
  • Risk assessment processes, which include processes for the estimation of human cancer potency using animal bioassay data and calculation of human exposure, entail uncertainties. In the exposure assessment process, exposure scenarios with various assumptions could affect the exposure amount and excess cancer risk. We compared risk estimates among various exposure scenarios of vinyl chloride, trichloroethylene and tetrachloroethylene in tap water. The contaminant concentrations were analyzed from tap water samples in Seoul from 1993 to 1994. The oral and inhalation cancer potencies of the contaminants were estimated using multistage, Weibull, lognormal, and Mantel-Bryan model in TOX-RISK computer software. In the first case, human excess cancer risk was estimated by the US EPA method used to set the MCL(maximum contaminant level). In the second and third case, the risk was estimated for multi-route exposure with and without adopting Monte-Carlo simulation, respectively. In the second case, exposure input parameters and cancer potencies used probability distributions, and in the third case, those values used point estimates(mean, and maximum or 95% upper-bound value). As a result, while the excess cancer risk estimated by US EPA method considering only direct ingestion tended to be underestimated, the risk which was estimated by considering multi-route exposure without Monte-Carlo simulation and then using the maximum or 95% upper-bound value as input parameters tended to be overestimated. In risk assessment for volatile organic compounds, considering multi-route exposure with adopting Monte-Carlo analysis seems to provide the most reasonable estimations.

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신도시 내 소각로 운영에 대한 건강영향평가 사례 연구 - 중금속 흡입에 따른 인체 위해도 평가 - (A Case Study on Health Impact Assessment from Incinerator Operation in New Towns - Human Risk Assessment due to Heavy Metals Inhalation -)

  • 명노일;이영수;신대윤
    • 환경영향평가
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    • 제19권3호
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    • pp.271-279
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    • 2010
  • We conducted a quantitative human health risk assessment with respect to inhalation of heavy metals for residents of housing developments in "new towns" where an incinerator will be operated within the area scheduled for construction thereof. To assess potential human health risk we calculated the amount of heavy metals emitted from the incinerator, and then forecasted the potential health impact on adjoining areas where new housing is to be developed (i.e. "new towns") at different altitudes by a using SCREEN-3 model. We assessed Cancer Risk (CR) caused by known carcinogens using the Inhalation Unit Risk criteria developed by the US Environmental Protection Agency. Notably, we assessed risk by determining concentrations of heavy metals on a floor by floor basis, as apartment buildings are to be constructed near the incinerator according to a pre-devised plan. Results indicated that cancer risk for most carcinogens exceeded US EPA standards for the highest locations at each collection point. This result indicates that construction of high buildings in areas adjoining incinerators is undesirable, and that measures to lower carcinogens are needed. The results of this study, which assessed health risk from exposure to heavy metals emitted from a nearby incinerator, can be useful in land use planning with respect to the location of housing developments in new towns, as well as the heights of any buildings constructed. Furthermore, the methodology deployed herein with respect to risk assessment can be helpful for policy makers and the general public in the event of conflicts regarding incinerator projects in the future. The results herein may also be of merit in determining priorities when establishing harm reduction measures for carcinogens at incinerators. However, the study does contain several limitations. The SCREEN-3 model, a kind of screening model that provides conservative results, can provide higher forecasted concentrations of air pollutants than other models. Moreover, although the incinerator in question is set to be a thermoselect type, domestic data for emissions from these incinerators is not available, and assumptions were based on a stoker type incinerator. Insufficient domestic data likewise compelled the use of data of USA, resulting in possible errors in results. Continued research will thus be required to develop systematic methodologies that address the foregoing factors and produce more reliable outcomes.