• 제목/요약/키워드: human damage

검색결과 1,981건 처리시간 0.03초

한랭지역(강원권)에서의 도로터널 라이닝부 피해 현황 연구 (A Study on Current Extent of Damage of Road Tunnel Lining in Cold Regions (Gangwon-do))

  • 진현우;황영철
    • 한국지반환경공학회 논문집
    • /
    • 제18권1호
    • /
    • pp.49-58
    • /
    • 2017
  • 국내 한랭지역(강원권)의 경우 낮은 연평균 기온에 의한 도로터널 라이닝 내구성에 문제가 발생하게 된다. 이에 따라 라이닝에 균열, 망상균열, 박락, 박리, 누수 등의 문제가 발생하며, 해마다 경제적 손실 및 인명피해가 증가하고 있는 실정이다. 하지만 국내에서는 기온에 따른 도로터널 라이닝의 피해에 대한 연구는 미비한 상태이다. 따라서, 본 논문에서는 한랭지(강원권) 터널 70개를 조사함으로써 현재 한랭지역의 피해현황을 분석하였고, 같은 한랭지역 중 비교적 따뜻한 기온을 가지는 강릉 지역과 기온이 낮은 홍천 지역의 터널 라이닝 피해를 비교함으로써 기온이 도로터널 라이닝에 미치는 영향을 분석하였다.

단세포전기영동법으로 평가한 흡연자의 백혈구 DNA손상 (Smoking Related DNA Damage in Human Lymphocytes Assessed by the Comet Assay)

  • 선수진;정해원;한정호
    • 한국환경성돌연변이발암원학회지
    • /
    • 제22권2호
    • /
    • pp.83-89
    • /
    • 2002
  • The single cell gel electrophoresis (comet) assay is one of the useful tools for the study of genetic damage in humans exposed to environmental mutagens and carcinogens. This study was undertaken to evaluate the status of DNA damage in peripheral lymphocytes depending on their sex, age, smoking habits, and other factors in normal healthy Korean population. The 99 volunteers included in the study and out of these, 36 volunteers were smoker and 63 volunteers were non-smoker aged between 20-59 years. All individual answered a questionnaire that assessed their general information including smoking habits and the extent of the environmental tobacco smoke (ETS) exposure, and blood samples were obtained. There was a statistically significant difference in the extent of DNA damage between smoker and non-smoker (p<0.001). A significant difference was also observed between male and female (p<0.001) and amongst the different group of age (p<0.005), however, correlation analysis showed that only smoking habit was a significant factor for DNA damage. No significant effect of smoking duration, number of cigarettes smoking a day, SPY (smoke pack years) in smokers and environmental tobacco smoke exposure in non-smokers on the status of DNA damage was observed.

  • PDF

Modal parameters based structural damage detection using artificial neural networks - a review

  • Hakim, S.J.S.;Razak, H. Abdul
    • Smart Structures and Systems
    • /
    • 제14권2호
    • /
    • pp.159-189
    • /
    • 2014
  • One of the most important requirements in the evaluation of existing structural systems and ensuring a safe performance during their service life is damage assessment. Damage can be defined as a weakening of the structure that adversely affects its current or future performance which may cause undesirable displacements, stresses or vibrations to the structure. The mass and stiffness of a structure will change due to the damage, which in turn changes the measured dynamic response of the system. Damage detection can increase safety, reduce maintenance costs and increase serviceability of the structures. Artificial Neural Networks (ANNs) are simplified models of the human brain and evolved as one of the most useful mathematical concepts used in almost all branches of science and engineering. ANNs have been applied increasingly due to its powerful computational and excellent pattern recognition ability for detecting damage in structural engineering. This paper presents and reviews the technical literature for past two decades on structural damage detection using ANNs with modal parameters such as natural frequencies and mode shapes as inputs.

LCD 모듈 품질의 자동검사 알고리즘의 개발 (Automatic Inspection Algorithm for LCD Module)

  • 이재혁
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
    • /
    • pp.64-66
    • /
    • 2005
  • In this paper, some automatic inspection algorithms for LCD module are suggested. Human eyes are very good for the inspection in many industrial areas. However, very bright LCD back lighting may cause permanent damage to the human eyes. Also, the growing size of the LCD make it more difficult for the human inspectors. Therefore, using camera set, automatic inspection process becomes very essential for the future LCD industry.

  • PDF

Risk analysis of dioxin in human breast milk

  • Choi, Shin-Ai;Han, Jee-Yeun;Park, Jong-Sei
    • 대한약학회:학술대회논문집
    • /
    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
    • /
    • pp.160.1-160.1
    • /
    • 2003
  • Persistent organic pollutants (POPs) have spread throughout the global environment to threaten human health and damage ecosystems. with evidence of POPs contamination in wildlife, human blood. and breast milk documented worldwide. Breast milk is an ideal medium for assessing exposures to POPs. POPs enter humans largely as contaminants of dietary animal products, where they sequester in adipose tissue, serum, and breast milk and equilibrate at similar levels on a fat weight basis. (omitted)

  • PDF

A Comprehensive Study for Two Damage Sites of Human Hair upon UV-B Damage

  • Song, Sang-Hun;Son, Seongkil;Kang, Nae Gyu
    • Korea Journal of Cosmetic Science
    • /
    • 제2권1호
    • /
    • pp.1-10
    • /
    • 2020
  • Protection mechanisms for skin damage of ultraviolet (UV) absorbers in personal care products for protection against UV are well studied, but not for hair protection. The purpose of this study is to describe and compare the changes of physical property produced in human hair by doses of the UV-B exposure causing protein degradation. To observe the change of physical properties in hair, the experimental intensity of UV-B exposure has been established on the basis of statistical data from official meterological administration as daily one hour sunlight exposure for two weeks. Polysilicone-15, ethylhexyl methoxycinnamate (OMC), and octocrylene were employed for UV-B absorber, and those were treated to hair swatch by rubbing wash through shampoo and conditioner. Bending rigidity displayed kinetically successive reduction at high doses of UV exposure up to the 8,000 s, and exhibited different level at each sample of UV-B absorber. However, the values of Bossa Nova Technologies (BNT) for shinning factor were already saturable at the 2,000 s exposure except that treated with polysilicone-15. The differential scanning calorimetry (DSC) to measure a strength of inner protein produces a successive reduction of enthalpy as like a reduction of bending rigidity upon UV exposure. Surface roughness from lateral force microscope (LFM) acquired immediately after UV exposure show a saturable frictional voltage which has been also found in a saturable BNT data as the time of UV exposure increases. Through researching the DSC and the LFM, shinning of hair was much correlated to the protein damage at the surface, and bending rigidity could be regulated by the protein structural damage inside hair. Therefore, the optimization of efficient strategy for simultaneous prevention of hair protein on the surface and internal hair was required to maintain physical properties against UV.

Current status of alert alien species management for the establishment of proactive management systems in Korea

  • Son, Seung Hun;Jo, A-Ram;Kim, Dong Eon
    • Journal of Ecology and Environment
    • /
    • 제45권4호
    • /
    • pp.237-254
    • /
    • 2021
  • Background: Some of the introduced alien species introduced settle, multiply, and spread to become invasive alien species (IAS) that threaten biodiversity. To prevent this, Korea and other countries legally designate and manage alien species that pose a risk to the environment. Moreover, 2160 alien species have been introduced in South Korea, of which 1826 animals and 334 plants are designated. The inflow of IAS can have negative effects such as ecosystem disturbance, habitat destruction, economic damage, and health damage to humans. To prevent damage caused by the inflow of IAS in advance, species that could potentially pose a risk to the environment if introduced in South Korea were designated as alert alien species (AAS). Results: The designation criteria were in accordance with the "Act on the Conservation and Use of Biological Diversity" and the "Regulations on the Ecological Risk Assessment of AAS and IAS" by the National Institute of Ecology. The analysis result of risk and damage cases indicated that mammals affect predation, competition, human economic activity, virus infection, and parasite infection. Birds have been demonstrated to affect predation, competition, human economic activity, and health. It was indicated that plants intrude on the ecosystem by competing with native species with their high-population density and capacity to multiply and cause allergic inducement. Interestingly, 300 species, including 25 mammals, 7 birds, 84 fishes, 28 amphibians, 22 reptiles, 1 insect, 32 spiders, 1 mollusk, 1 arthropod, and 99 plants, are included in the list of AAS. Conclusions: AAS designation plays a role in preventing the reduction of biodiversity by IAS in South Korea and preserving native species. Moreover, it is determined to provide considerable economic benefits by preventing socio-economic losses and ecological damage.

Nrf2-mediated activation of HO-1 is required in the blocking effect of compound K, a ginseng saponin metabolite, against oxidative stress damage in ARPE-19 human retinal pigment epithelial cells

  • Cheol Park;Hee-Jae Cha;Kyoung-Seob Song;Heui-Soo Kim;EunJin Bang;Hyesook Lee;Cheng-Yun Jin;Gi-Young Kim;Yung Hyun Choi
    • Journal of Ginseng Research
    • /
    • 제47권2호
    • /
    • pp.311-318
    • /
    • 2023
  • Background: The beneficial effects of compound K (CK) on different chronic diseases have been shown to be at least related to antioxidant action. Nevertheless, since its antioxidant activity in human retinal pigment epithelial (RPE) cells is still unknown, here we investigated whether CK alleviates oxidative stress-stimulated damage in RPE ARPE-19 cells. Methods: The cytoprotective consequence of CK in hydrogen peroxide (H2O2)-treated cells was evaluated by cell viability, DNA damage, and apoptosis assays. Fluorescence analysis and immunoblotting were performed to investigate the inhibitory action of CK on reactive oxygen species (ROS) production and mitochondrial dysfunction. Results: H2O2-promoted cytotoxicity, oxidative stress, DNA damage, mitochondrial impairment, and apoptosis were significantly attenuated by CK in ARPE-19 cells. Furthermore, nuclear factor erythroid 2-related factor 2 (Nrf2) phosphorylation level and its shuttling to the nucleus were increased, which was correlated with upregulated activation of heme oxygenase-1 (HO-1). However, zinc protoporphyrin, a blocker of HO-1, significantly abrogated the preventive action of CK in H2O2-treated ARPE-19 cells. Conclusion: This study indicates that activation of Nrf2/HO-1 signaling by CK plays an important role in rescuing ARPE-19 cells from oxidative cellular damage.

지속가능한 의류관리를 위한 최적 세탁코스 연구 - 세탁코스, 세탁성, 섬유손상도, 세제농도를 중심으로 - (Optimal washing course for sustainable laundering and care - Focusing on the washing course, detergency, fabric damage and detergent concentration -)

  • 백성필;박세은;박명자
    • 한국의상디자인학회지
    • /
    • 제24권4호
    • /
    • pp.1-9
    • /
    • 2022
  • The purpose of this research is to improve sustainable clothes care by comparing household washer's standard course and quick course. Detergency at each course was classified by laundry weight, detergent concentration, and soils. Also, fabric damage from each course was compared. Washing experiments were carried out using two types of washing machines and three types of detergents. Using the standard soiled fabrics of EMPA 108 set, detergency was compared by laundry weight, soil, and detergent concentration. Additionally, fabric damage was evaluated using the mechanical action of MA-40. The results of the research were as follows. First, a standard course, having more working time exhibited better detergency than a quick course. However, the detergency deviation under 6kg laundry weight was as low as 9.0%. Second, detergency by the type of soil was more effective in standard course than in a quick course, but hydrophilic protein soils had a small detergency deviation at 7.6%. Moreover, hydrophobic oil, complex, and particulate soils had a higher deviation at 19.7% Third, fabric damage was in proportion to operating time. Fourth, a quick course showed approximately 80% detergency regardless of the type of detergent. in the case of using 50% of the recommended allowance by the detergent manufacturer. In conclusion, reducing the operating washing time and detergent concentration is in accordance with increasing sustainability, in the case of washing with lightly soiled fabrics under 6kg of laundry weight.

위험물질(유류·HNS) 해양사고 인명 및 환경피해 위험도 분석에 관한 연구 (A Study on Risk Analysis of Human Loss and Environmental Damage Caused by Hazardous Materials (Oil and HNS) Marine Accidents)

  • 조심정;김동진
    • 해양환경안전학회지
    • /
    • 제23권6호
    • /
    • pp.603-612
    • /
    • 2017
  • 유류와 위험 유해물질(Hazardous and Noxious Substances, 이하 HNS)을 포함하는 위험물질의 해상운송 중에 발생하는 사고가 증가하고 있어, 이러한 위험물질 해양사고를 방지할 수 있는 예방대책을 마련해야 할 것이다. 이를 위해 국내에서 발생하는 위험물질 해양사고 자료(2002~2014)를 수집하여 인명 및 환경 위험도를 분석하였으며, 사고원인 규명 및 적절한 예방대책이 필요한 우선 안전관리분야를 파악하고자 하였다. 인명위험도는 선박 수리 및 탱커세정(tank cleaning) 작업과정에서 발생하는 폭발 및 인명사고 중 질식 등이 높은 것으로 분석되었다. 환경위험도는 충돌, 좌초 등에 의한 유출사고로 인해 발생하였다. 또한 비포장 상태의 위험화물을 선박에 적재 중 취급부주의로 인하여 유출사고가 일어났다. 다수의 사고는 적합한 안전장비 미착용, 취급 부주의 등 인적오류로 인한 사고로서 관리 감독을 강화하고, 주기적인 교육 훈련을 통하여 사고 저감이 가능하다. 위험물질 해양사고를 예방하기 위해서는 물질 자체 고유의 특성상 유해성과 위험성을 지닌 위험물질(유류와 HNS)에 대한 안전관리를 더욱 강화해야 한다.