• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2759-2763
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• 2012

Objectives: Compared with Western countries, the incidence rates for breast cancer in China are still low. However, breast cancer appears to be hitting Chinese women at a much younger age, with a peak between 40 and 50 years. Furthermore, breast tumors of Asian women have molecular and genetic characteristics that are different from those of Caucasian women. Methods: A community-based study was designed to evaluate the relationship between lifestyles and breast cancer risk in Chinese women residing in Guangzhou. 16,314 subjects completed the questionnaire. Potential confounding factors included sociodemographic characteristics. Results: 33 individuals reported a history of breast cancer, yielding a prevalence rate of 202.3/100000. Associations between subjects' demographic and breast cancer risk factors were assessed. Breast cancer is associated with family history of breast cancer, X-rays received, benign breast disease and hyperlipoidemia or hypercholesteremia with elevated odds ratios. Conclusions: Family history of breast cancer, X-ray received benign breast disease and hyperlipoidemia or hypercholesteremia were significantly associated with risk of breast cancer and may havepotential for breast cancer risk assessment.

• Journal of Animal Science and Technology
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• v.57 no.11
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• pp.32.1-32.8
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• 2015

Peste des petits ruminants (PPR) is considered to be one of the main constraints to enhancing the productivity of goats and sheep in regions where it is present and becoming endemic. PPR was recognized in Pakistan in early 1990s but got importance during the Participatory Disease Surveillance (PDS) of Rinderpest Eradication Campaign. Lot of research work has been initiated during last decade towards disease epidemiology, risk factor recognition, laboratory diagnosis, vaccination and demonstration of control strategies. Although there are ongoing projects working towards the progressive control of the disease in country yet there is need to have a national level control program for PPR. Also there is need to have comprehensive social economic surveys, disease hot spot recognition and identification of role of other species in disease transmission. With combined efforts of local and national authorities and political will, there is high likelihood that this devastating disease can be controlled and eventually eradicated in near future.

• Clinical and Experimental Pediatrics
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• v.50 no.2
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• pp.127-131
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• 2007

Fever of unknown origin (FUO) has been a convenient term used to classify patients who warrant a particular systemic approach to diagnostic evaluation and management. The greatest clinical concern in evaluating FUO is identifying patients whose fever has a serious or life-threatening cause when a delay in diagnosis could jeopardize successful intervention. Thorough history and complete physical examination are critical to uncover the etiologic diagnosis. Most cases of FUO in children are caused by atypical presentations of common diseases rather than by typical manifestations of rare disorders. Selection of diagnostic tests and speed of investigation should be guided by a knowledge of the disease severity, patient age, epidemiologic and geographic information, and any positive findings from a detailed history and physical examination. The three most common causes of FUO in children are infectious diseases, connective tissue diseases, and malignancy. In general, the prognosis of FUO in children is better than that of adults. Although the outcome is dependent on the primary disease process, fever abates spontaneously in most cases in whom the cause of fever remains unclear.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.3
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• pp.734-741
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• 2008

The modern people effort to lead good life. Specially, the patients which prevention of a disease only is cure from this diabetes patient, the old and weak, the hospitals needing a treatment through exercises, and receive medical treatment in houses cure exercise according to exercise prescription. These papers developed a Ubiquitous Care Management system based on Zigbee. This is a system supporting so as accumulation manages the exercise history information that occurred when get exercises prescription, and exercise systematically, and to do preventive of a disease. Can confirm own exercise history and health information through web pages, and this system notifies contents about an exercise treatment to patients as use a cellular phone.

• Journal of Korean Medical classics
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• v.22 no.2
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• pp.107-126
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• 2009

King Seonjo, the second son of King Jeongjo, is the twenty-third King of the Joseon Dynasty. He suffered mainly from spleen-stomach weakness syndrome[脾胃虛弱], neurasthenic neurosis and abscess according to the Annals of the Joseon Dynasty[朝鮮王朝實錄]. He experienced chicken pox at the age of twelve, measles at thirteen, smallpox at sixteen. In his twenties he was ill with chronic breakdown due to the spleen-stomach weakness[脾胃虛弱], accompanied by neurasthenia. Abscess occurred during his twenties and the septicemia induced by abscess worsening led him to death. Most treatments were herb-extract medication taken orally, and to some extent ointment care was applied as a cure for abscess.

• Tuberculosis and Respiratory Diseases
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• v.77 no.4
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• pp.155-160
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• 2014

Chronic obstructive pulmonary disease (COPD) is characterized by a diverse array of pulmonary and nonpulmonary manifestations, but our understanding of COPD pathogenesis and the factors that influence its heterogeneity in disease presentation is poor. Despite this heterogeneity, treatment algorithms are primarily driven by a single measurement, forced expiratory volume in 1 second ($FEV_1$) as a percentage of its predicted value ($FEV_1%$). In 2011, a major shift in Global Initiative for Chronic Obstructive Lung Disease (GOLD) treatment recommendations was proposed that stratifies patients with COPD on the basis of symptoms and exacerbation history. This article reviews the work reported in 2013 that enlightens our understanding of COPD with respect to COPD classification systems, phenotype, biomarker, exacerbation, and management for patients with COPD.

• The Journal of Korean Medical History
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• v.15 no.1
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• pp.3-10
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• 2002

Acupuncture and moxibustion of theory had begun in the "Nei-Jing" and "Nan-Jing". But definite acupuncture needling techniques had been investigated after Jin and Yuan Dynasty. After Ming Dynasty, much more scholars had studied about definite acupuncture needling techniques. So various techniques and theorys about how to select and operate needling points appeared in print. "Zi-Wu-Liu-Zhu-Zhen-Jing", "Zhen-Jing-Zhi-Nan", "Shen-Ying-Jing", "Zhen-Jiu-Da-Quan" and so forth are representative books. But these books include mutually different techniques, so then scholars would be thrown into confusion. So I have analysed acupuncture and moxibustion of theory into Ki(vital energy)-blood's circulation, disease region, time, sex, restorative and restrictive techniques. As a result, I have known that every restorative and restrictive techniques and theories are connected with Ki(vital energy)-blood's circulation and practical application methods are decided by sex, time, disease region, pathogenic energy.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.17 no.3
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• pp.92-95
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• 2017

Fabry disease (FD) is an X-linked lysosomal storage disorder caused by an ${\alpha}$-galactosidase A (GLA, MIM 300644) enzyme deficiency due to pathogenic variants in the ${\alpha}$-galactosidase A gene (GLA). The disease leads to accumulation of globotriaosylceramide (Gb3) and related glycophospholipids affecting nearly all major organ systems, with the primary sites damaged by Gb3 including renal glomeruli, myocardium, neurons of the dorsal ganglion and autonomic nervous system, and vascular endothelial and smooth muscle. Progressive deposition in these organ systems present with various clinical manifestations including acroparesthesia, renal failure and heart failure. Here, we report a Chinese male diagnosed with Fabry disease in his late $4^{th}$ decades showing improvement of acroparesthesia during enzyme replacement therapy (ERT). A 48-year-old Chinese man who presented with chronic recurrent severe burning pain in his fingers and toes since the age of 10, with worse involvement of the former visited to our clinic for further evaluation. His medical history included a transient ischemic attack aged 40 and diagnosed with stage 4-5 chronic kidney disease aged 47. In the family history, the patient's brother was found to be have Fabry disease 1 month before his visit. Except for his brother, all other members of the family are healthy. Based on his medical history and family history, he was strongly suspicious for Fabry disease. He was found to have a galactose-alpha-1,3-galactose level 4.96 (Reference range, 42.5-67.9) suggestive of Fabry disease. The followed sequencing of GLA coding region in our patient revealed hemizyosity for the mutation c.988C>T (Q330X) in Exon 7. Since ERT start, he showed significant improvement in his symptoms of burning sensation of fingers and toes. On the contrary, due to deteriorating kidney function even with ERT, he is considered for kidney transplantation. Despite of diagnostic delay until late 4th decades, ERT showed a potential improvement of acroparesthesia in our patient. However, late start of ERT can lead to poor outcome in multiorgan function. Therefore, early diagnosis with high index of suspicion followed by continuous ERT with regular monitoring have an impact on quality of life in Fabry disease.

• The Journal of Korean Medical History
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• v.17 no.2
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• pp.129-144
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• 2004

The King Hyo-Jong is the 17th King in the Chosun dynasty. King Hyo-Jong carried forward the subjugation of the northern areas, but the subjugation of the northern areas was failed for the reason that he was died in 41 years old. After that time, his death is wrapt in a shround of suspicion, such as a rumor of killing by poison. But the cause of his death in direct was the septicemia arised from the boil. Besides, We suppose that he was afflicted with gout and renal failure.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.10 no.3
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• pp.276-282
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• 2003

Purpose: The purpose of this study was to investigate smoking history and quality of life in the patients with coronary artery disease (CAD). Method: Data were collected from 157 men who quit smoking or attempted to quit smoking. Quality of life was measured with the SCQoL(smoking cessation quality of life) scale which was developed by Olufade et al. (19?19), and includes 5 factors; social interactions, cognitive functioning, self control, anxiety, and sleep. Result: The patients usually smoking in their twenties (61.8%), continued to smoke for over 30 years (70.7%), and smoked 20-29 cigarettes a day (50.3%). The total mean scores for the SCQoL was $50.48{\pm}7.11$. Of the 5 factors, self control had the highest mean score ($17.00{\pm}3.79$). Patients who began smoking in their twenties had a higher SCQoL. However, there were no significantly differences in the SCQoL according to duration of smoking or amount of smoking per day. Conclusion: Age when smoking is begun is an important variable to explain SCQoL in patients with CAD. But, further study is needed to identify the influence of other variables such as duration and amount of smoking.