DOI QR코드

DOI QR Code

Risk Assessment of Breast Cancer in Guangdong, China: A Community-based Survey

  • Published : 2012.06.30

Abstract

Objectives: Compared with Western countries, the incidence rates for breast cancer in China are still low. However, breast cancer appears to be hitting Chinese women at a much younger age, with a peak between 40 and 50 years. Furthermore, breast tumors of Asian women have molecular and genetic characteristics that are different from those of Caucasian women. Methods: A community-based study was designed to evaluate the relationship between lifestyles and breast cancer risk in Chinese women residing in Guangzhou. 16,314 subjects completed the questionnaire. Potential confounding factors included sociodemographic characteristics. Results: 33 individuals reported a history of breast cancer, yielding a prevalence rate of 202.3/100000. Associations between subjects' demographic and breast cancer risk factors were assessed. Breast cancer is associated with family history of breast cancer, X-rays received, benign breast disease and hyperlipoidemia or hypercholesteremia with elevated odds ratios. Conclusions: Family history of breast cancer, X-ray received benign breast disease and hyperlipoidemia or hypercholesteremia were significantly associated with risk of breast cancer and may havepotential for breast cancer risk assessment.

Keywords

References

  1. Cao KJ, Fan QY, Liu YL, et al (2008). Cancer incidence and mortality in Guangzhou City from 2000 to 2002. Ai Zheng, 27, 225-30.
  2. Colditz GA, Rosner B (2000). Cumulative risk of breast cancer to age 70 years according to risk factor status: data from the Nurses' Health Study. Am J Epidemiol, 152, 950-64. https://doi.org/10.1093/aje/152.10.950
  3. Gaudet MM, Britton JA, Kabat GC, et al (2004). Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status. Cancer Epidemiol Biomarkers Prev, 13, 1485-94.
  4. Hesketh T, Lu L, Xing ZW (2005). The effect of China's onechild family policy after 25 years. N Engl J Med, 353, 1171-6. https://doi.org/10.1056/NEJMhpr051833
  5. Lilienfeld AM, Coombs J, Bross ID, et al (1975). Marital and reproductive experience in a community-wide epidemiological study of breast cancer. Johns Hopkins Med J, 136, 157-62.
  6. Linos E, Spanos D, Rosner BA, et al (2008). Effects of reproductive and demographic changes on breast cancer incidence in China: a modeling analysis. J Natl Cancer Inst, 100, 1352-60. https://doi.org/10.1093/jnci/djn305
  7. Lissowska J, Gaudet MM, Brinton LA, et al (2008). Intake of fruits, and vegetables in relation to breast cancer risk by hormone receptor status. Breast Cancer Res Treat, 107, 113-7.
  8. Leong SP, Shen ZZ, Liu TJ, et al (2010). Is breast cancer the same disease in Asian and Western countries? World J Surg, 34, 2308-24. https://doi.org/10.1007/s00268-010-0683-1
  9. Lyle KC (1980). Female breast cancer: distribution, risk factors, and effect of steroid contraception. Obstet Gynecol Surv, 35, 413-27. https://doi.org/10.1097/00006254-198007000-00001
  10. Mao SH, Jiang J, Sun X, et al (2011). Timing of menarche in Chinese girls with and without adolescent idiopathic scoliosis: current results and review of the literature. Eur Spine J, 20, 260-5. https://doi.org/10.1007/s00586-010-1649-6
  11. McPherson K, Vessey MP, Neil A, et al (1987). Early oral contraceptive use and breast cancer: results of another casecontrol study. Br J Cancer, 56, 653-60. https://doi.org/10.1038/bjc.1987.261
  12. Pathak DR, Whittemore AS (1992). Combined effects of body size, parity, and menstrual events on breast cancer incidence in seven countries. Am J Epidemiol, 135, 153-68.
  13. Ravert PK, Huffaker C (2010). Breast cancer screening in women: An integrative literature review. J Am Acad Nurse Pract, 22, 668-73. https://doi.org/10.1111/j.1745-7599.2010.00564.x
  14. Shi J, Zhang M, et al (2010). Body mass index and its change in adulthood and breast cancer risk in China. Asian Pac J Cancer Pre, 11, 1213-8.
  15. Siegel R, Naishadham D, et al (2012). Cancer statistics, 2012. CA Cancer J Clin, 62, 10-29. https://doi.org/10.3322/caac.20138
  16. Woo PP, Kim JJ, Leung GM (2007). What is the most costeffective population-based cancer screening program for Chinese women? J Clin Oncol, 25, 617-24. https://doi.org/10.1200/JCO.2006.06.0210
  17. Zhu YY, Zhou L, et al (2011). Relationship between soy food intake and breast cancer in China. Asian Pac J Cancer Pre, 12, 2837-40.

Cited by

  1. Family History Attributes and Risk Factors for Breast Cancer in Turkey vol.15, pp.6, 2014, https://doi.org/10.7314/APJCP.2014.15.6.2841