• Journal of Radiation Protection and Research
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• 제36권2호
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• pp.93-98
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• 2011

C57BL/6 마우스에서 자외선 B(UV-B) 조사에 의한 표피 멜라닌세포의 변화에 대한 헤모힘의 효과를 관찰하였다. 마우스에 UV-B를 매일 $80\;mJ{\cdot}cm^{-2}$ ($0.5\;mW{\cdot}sec^{-1}$)씩 7일간 조사하고 헤모힘을 UV 조사 전 또는 조사 후에 복강내주사, 경구투여 또는 피부에 도포하여 멜라닌세포 형성 억제효과 및 형성된 멜라닌세포에 대한 미백효과를 dihydroxyphenylalanine (DOPA) 염색으로 관찰하였다. 마우스의 귀등쪽 표피를 분리하여 관찰한바, 정상대조군에서는 $mm^2$당 13~15개의 멜라닌세포가 관찰되었다. 멜라닌세포 형성 억제 실험에서는 평균치를 기준으로 복강내주사군에서 44.9%, 경구투여군에서는 35.6%의 억제효과를 보였고, 피부도포군에서는 30% 이상의 유의성 있는 억제 효과가 관찰되었다. 형성된 멜라닌세포의 감소 효과 실험에서는 평균치를 기준으로 복강내주사군의 경우 3주 및 6주에 각각 18.3%, 12.5%의 감소 효과가 관찰되었고, 경구투여군에서는 3주 및 6주에 각각 16.9%, 20.4%의 감소 효과가 관찰되었으며, 피부도포군의 경우 3주에 32.0%, 6주에 31.2%의 감소 효과를 보였다. 이상의 결과는 헤모힘이 UV에 의한 멜라닌세포 형성 억제제 및 미백제로서의 적용 가능성을 제시하였다. 구성 단미생약, 유효성분, 멜라닌세포 형성 억제 및 형성된 세포의 감소 촉진에 관여하는 작용 기전에 대한 추가 연구가 필요하다.

• 대한한의학원전학회지
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• 제26권3호
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• pp.1-9
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• 2013

Objective : In South Song era, Choe Ga-eon(崔嘉彦) built Seowonam(西源庵), lived as a hermit and communicated with Juja(朱子) in LuShan(廬山), JiangXi province(江西省), JiuJiang city(九江市). Maekgyeol(脈訣) written by him significantly influenced the forthcoming medical doctors, who took over his studies and were called the school of Seowon. Little information about his life and his successors encouraged this study. Method : The core contents of Maekgyeol(脈訣), his life based on Waryongamgi(臥龍庵記) and Seowongamgi(西源庵記) written by Juja(朱子) and his successors on the basis of various medical books were investigated. Result : The Seowonam(西源庵) is located at the entrance of xiufeng Scenic spot(秀峰景區) which is 6km west from center of Xingzi county(星子縣), JiangXi province(江西省), JiuJiang city(九江市). The points of Maekgyeol(脈訣) are inferring the symptom of wind, energy, cold and heat by categorizing seven exterior and eight interior pulse into four pulses of float, sink, slow and quick and diagnosing a disease of three warmer and the five viscera and the six entrails by subordinating four pulses to Chon, Gwan, and Cheok(寸關尺). By writing the book of Sawonron(四原論) he clarified the clinical point, pulse, disease, symptom, treatment with learning the cause of a disease through pulse, understanding the symptom through a disease, and giving a remedy through a symptom. Then he communicated with Juja(朱子) assigned to NanKangJun(南康軍) as a ruler. He helped Juja(朱子) to build Waryongam(臥龍庵) and Juja(朱子) wrote Seowonamgi(西源庵記) for him. Conclusion : The members of medical doctors of the school of Seowon were Choe Ga-eon(崔嘉彦) and his follower Yu Gae(劉開), Yugae's disciple Eom Yong-hwa(嚴用和) and Ju Jong-yang(朱宗陽) and Ju Jong-yang's disciple Jang Do-jung(張道中). They, who were famous for pulse, had contributed to advancing study of pulses in the field of oriental medicine.

• 한국의사학회지
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• 제26권2호
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• pp.149-160
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• 2013

King Sunjong was the 27th King and the last King in the Joseon Dynasty. He lived an unhappy life as the prince and the King of perishing country. At the age of 22, He witness the death of his mother Queen Myeongseong by Japanese assassin. He has a weak constitution and have many diseases. He get varicella(水痘) in infancy, and suffered from smallpox(紅疫) at 6, and catched the measles(天然痘) at 12. At the age of 25, Having drunk the coffee that contained opium(阿片), he had bloody excrement(血便) and lose the 18 teeth. The Symptoms that appeared frequently at adult age are indigestion(滯症), diarrhea(泄瀉), trophedema(足部浮腫), odontopathy(齒科疾患) etc. This indigestion(滯症) and diarrhea(泄瀉) are occurred by gastroenteropathy(胃腸病). This odontopathy(齒科疾患) is the aftereffect from having 18 false teeth. We assume that this trophedema(足部浮腫) is occurred by cardiac disease(心臟病) and renal disease(腎臟病). The chronic diseases of King Sunjong are gastroenteropathy(胃腸病), renal disease(腎臟病), cardiac disease(心臟病), rheumatism. We assume that the immediate cause of his death is the aggravation of the renal disease(腎臟病) and cardiac disease(心臟病). The medical treatments for him are hardly included in "Formal Records of the Joseon Dynasty(朝鮮王朝實錄)" which is the prime governmental document. Many royal doctors in court used the traditional Korean medicine, but western doctors from Japan often treated him by medical techniques such as injection(注射), consperg(散藥), liquid medicine(水藥).

• Journal of Chest Surgery
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• 제24권2호
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• pp.123-134
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• 1991

Twenty eight patients had undergone repair of an isolated complete atrioventricular septal defect between April 1986 and September 1990 in Seoul National University Children`s Hospital. The group comprised 13 male and 15 female patients. They ranged in age from 2 months to 8 years[mean 18.6months] and in weight from 3. 4kg to 23kg[mean 9.0$\pm$4.6kg]. They were analysed as Rastelli type A in 17 patients, Rastelli type B in 2 patients, and Rastelli type C in 9 patients. Seven patients had concomitant Down`s syndrome. All patients had large left-to-right shunt[mean pulmonary to systemic flow ratio 3.5 $\pm$2.2 ranging from 0.68 to 10.0] and high pulmonary systolic pressure[mean 74$\pm$18.8mmHg, ranging from 35 to 110]. In 11 patients, one patch technique was used to close the atrial and ventricular septal defect and 16 patients were undergone by two patch technique. We urgently managed only one patient by pulmonary artery banding whose anatomy was Rastelli type C and severe mitral regurgitation was identified. Postoperative complete A - V block was noted in 3 patients, two of whom were dead in operating room due to combined LVOTO and myocardial failure, and one patient with Rastelli type C was undergone by VVI type permanent pacemaker insertion 1wk later after two patch technique, but we had to manage him by modified Konno operation and total correction due to LVOTO and VSD leakage and severe mitral regurgitation 3 years later. Another two reoperation cases due to severe mitral regurgitation after two patch technique were undergone, one of whom we managed by mitral annuloplasty 3 months later but aggravated mitral regurgitation made us to control him by MVR 3 months later. Another one case of VSD leakage and tricuspid regurgitation was managed by total correction but she died of respiratory insufficiency 14 days later. We experienced pulmonary hypertensive crisis in 3 patients, who were dead in two cases comparing with one control case. So operative mortality is 9/27[33.6%], in one patch group of 3/11[29.2%] comparing with two patch group of 6/16[37.5%]. In summary, causes of death were pump weaning failure, myocardial failure and low cardiac output syndrome and pulmonary hypertensive crisis, resp. failure, complete AV block. Mean follow up period is 15.8$\pm$10.7 months[ranging from 3months to 37 months]

• 한국치위생학회지
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• 제9권3호
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• pp.493-506
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• 2009

The purpose of this study was to examine the awareness of people in general characteristics about oral malodor. The subjects in this study are 184 people who visited the clinical practice lab at J health college to get their teeth scaled. After conducting a survey from May 1 to June 3, 2008, we selected four different ares and then analyzed the answer sheets from 179 respondents including smoking/nonsmoking, scaling experience, toothbrushing frequency and the use of oral hygiene supplies. SPSS WIN 12.0 program was used to make a frequency analysis and cross analysis. The findings of the study are as follows: 1. Concerning an intention of treatment for oral malodor, 37.4% didn't intend to receive treatment even in case of having bad breath. 28.5% didn't yet have any definite idea about that, and 20.7% had no mind to do that at all. 10.6% had an intention to receive treatment, and 2.8% want to receive treatment. 2. As for how to cope with oral malodor in case of suffering from it, 47.5% chewed gums or ate candy. 25.1% scarcely care about that, and 15.6% covered their mouth whenever they spoke. 9.5% had little confidence about talking to others, and 2.2% found it difficult to build an amicable interpersonal relationship. 3. Concerning what to do about another person's oral malodor, 40.8% did nothing, and 19% talked to the person about that. 17.3% gave him or her chewing gum. Among their oral health characteristics, toothbrushing frequency made a significant difference to the way they responded to another person's oral malodor(p<.05). 4. As to subjective feelings about another person's oral malodor, 41.9% just found it bearable. 36.9% were a little displeased, and 9.5% never felt bad about another person's bad breath. 8.9% tried to avoid the person, and 2.8% advised him or her to chew gum. 5. Regarding an intention of participating in a oral malodor program, 46.9% had no idea about that. 31.3% intended to participate in the program, and 13.4% wanted to do that without fail. 6.1% had no mind for that, and 2.2% were never going to do that. Among characteristics of the user oral hygiene device made a significant difference whether to participating in the oral malodor program(p<.05).

• 아동학회지
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• 제2권
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• pp.17-30
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• 1981

This study is designed to analyze the child's behaviour development and consider parent's expectation toward it. In the research of the aspect of child's behaviour development, first, this study will analyze the change and development a child shows according to his age, sex, and the community where he is brought up, and then, the relationship between child's behaviour development and parent's expectation toward it. (1) Child's Behaviour Development. a) According to Age. At the age of three ; In such behaviours as wiping nose, dressing, brushing teeth, putting on coat alone, going to toilet for B.M., going on errands, and playing contentedly alone, washing hands, greeting his elders, a child at the age of three to four shows a rapid development, and therefore it seems better to train a child in these behaviors age of three. At the age of four ; In such behaviors sharing cakes with friends, riding on a tricycle, a child shows great development, at the age of four to five, and therefore it seems better to train him in them at the age of four. At the age of five ; In such behaviors as combing hair, putting toys away in proper place, telephoning a child shows great development at the age of five to six, and therefore it seems better to train him in them at the age of five. b) According to sex and community. As a whole, there is little difference between sexes and the communities. It can be estimated from this that sex or the community has on the whole no great influence on the basic aspects of child's behavior development. (2) Parent's expectation. On the whole parent's expectation falls short of a child's development in behaviors ; especially, bathing himself, dressing, going to toilet for B.M, going to toilet to urinate, telephoning, etc. This tendency is consficuous in the case of three or four year old children. This results from parent's protecting in excess their children and reducing the opportunities to encourage the children's independence by delaying the babyhood. (3) The relationship between child's behaviour development and parent's expectation. a) On the whole, the behaviour of a child is at a higher level than parent's expectation. b) As a child grows from three years to six, his behaviour develops on the whole in accordance with the increase of parent's expectation. But the level of the former is lower than that of the latter. c) According to computing a coefficient of correlation is as follows. 3 years old ; .84 4 years old ; .90 5 years old ; .87 6 years old ; .89 It shows there is a high correlation between child's Behaviour and Parent's Expectation.

• Journal of Acupuncture Research
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• 제27권1호
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• pp.51-64
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• 2010

Objectives : To introduce and compare various headache measurement tools, in order to provide fundamental information for future clinical trials and development of oriental medicine measurement tools. Methods : Eight headache assessment scales, Migraine-Specific Quality of Life Questionnaire(MQoLQ), Migraine-Specific Quality of Life(MSQOL), Migraine-Specific Quality of Life Questionnaire(MSQ), The Headache Impact Questionnaire(HImQ), Headcahe Needs Assessment Survey(HANA), Henry Ford Headache disability Inventory(HDI), Migraine Disablity Assessment Scale(MIDAS) and Headache Impact Test(HIT-6), were searched through Pubmed. General character, the process of development, verification of reliability, internal consistency, responsiveness to patient's change and validity were reviewed. Results : In assessing the quality of life of migraine patients, MQoLQ can be used to measure the change within 24 hours, MSQ and MSQOL can be used to measure the change during a relatively longer period of time. The frequency and bothersomeness of headache can be easily measured by HANA. HImQ can be used to measure the intensity of headache and the influence on normal daily activities. HDI can measure the emotional difficulties of headache patients. HIT-6 and MIDAS makes measurements possible in a short period of time, and the reliability and validity have been verified numerously. HIT-6 and MIDAS are the most frequently used measurement tools because they are simple and easy for both the assessor and the patient to understand and use. Conclusions : In this study, various headache assessment tools have been reviewed. The assessed tools were widely used after being verified for their reliability and validity. We hope this study provides fundamental information in establishing future clinical trial and clinical practice guidelines. We also hope this study to contribute to the development of an oriental medicine assessment tool for headache.

• 대한한방내과학회지
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• 제43권6호
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• pp.1239-1246
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• 2022

Objectives: The purpose of this study was to report the effectiveness of Korean medicine in the treatment of reflux esophagitis. Methods: A 62-year-old male patient had reflux esophagitis that occurred one year after a proximal gastrectomy for gastric ulcer in 2020. The patient underwent drug treatment in 2021 and inpatient treatment in 2022 at Mokpo Hankook Hospital, but he did not improve. We treated him with Korean medical treatments, including herbal medicines (Pyungjingunbi-tang-gami), acupuncture, and moxibustion. His symptom severity was assessed with a daily visual analog scale (VAS) for heartburn, upper abdomen pain, and acid reflux. Results: After treatment, the patient's symptoms were improved. The severity of heartburn and acid reflux was reduced from VAS 7 to VAS 1, and his upper abdomen pain was improved from VAS 6 to VAS 1. The symptom frequency was also reduced. Conclusion: Korean medicine treatment could be an effective and quick treatment for reflux esophagitis.

• 제어로봇시스템학회논문지
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• 제21권6호
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• pp.571-576
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• 2015

This paper proposes an auto-parking controller for omnidirectional mobile robots. The controller uses the multi-sensor system including ultrasonic sensor and camera. The several ultrasonic sensors of robot detect the distance between robot and each wall of the parking lot. The camera detects the global position of robot by capturing the image of artificial landmarks. To improve the accuracy of position estimation, we applied the extended Kalman filter with adaptive fuzzy controller. Also we developed the fuzzy control system to reduce the settling time of parking. The experimental results are presented to verify the usefulness of the proposed controller.

• Archives of Reconstructive Microsurgery
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• 제22권2호
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• pp.69-73
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• 2013

Facial esthetics and smiling are key components in nonverbal communication and have an important role in determination of the first impression of a person. The various components of the smile in dental esthetics include Gingival scaffold, lip framework, and Teeth. The periodontist creates a smile by performing various periodontal plastic microsurgery procedures for management of mucogingival problems. A 25-year-old patient reported to the Department of Periodontology at Teerthanker Mahaveer Dental College and Research Center, Moradabad, Northern India, with the chief complaint of long looking teeth in the upper jaw, making him conscious while smiling. Miller class I gingival recession with Maxillary left canine (23) was diagnosed. Periodontal plastic microsurgery employing double papilla grafting with connective tissue graft harvested from the palate in order to cover denuded root was performed using microsurgical instruments and microsuturing with 6-0 suturing material under magnification. Healing was uneventful, with achievement of 100% root coverage of denuded root after three months. The patient was highly impressed and satisfied with his enhanced smile.