• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.11
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• pp.4745-4750
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• 2011

A HIL(hardware-in-the-loop) system was established and the simulation was carried out to determine whether the system operates normally. The system consists of turbocharger test bench, HIL platform with real time S/W and DAQ, and engine model using Matlab/Simulink. In the simulation the supplied fuel rate is changed step-by-step from 1.8944 kg/h to 4.7360 kg/h. The change of air-fuel ratio is analyzed and observed whether the air-fuel ratio follow the target air-fuel ratio 32. When the supplied fuel rate is changed, the air-fuel ratio is converged to the target air-fuel ratio after about 20 seconds. And the vane duty ratio of turbine and the boost pressure of compressor are also changed properly. Therefore this HIL system can be used to develop the new turbocharger and improve the performance of the modified turbocharger.

• Journal of Power Electronics
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• v.13 no.1
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• pp.104-112
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• 2013

This paper presents a comparative evaluation of various topologies for three-phase power converters using the hardware-in-the-loop (HIL) simulation technique. Various switch-mode AC-DC power converters are studied, and their performance with respect to total harmonic distortion (THD), efficiency, power factor and losses are analyzed. The HIL-simulation is implemented in an Altera Cyclone II DE2 Field Programmable Gate Array (FPGA) Board and in the Matlab/Simulink environment. A comparison of the simulation and HIL-simulation results is also provided.

• Journal of Microbiology and Biotechnology
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• v.23 no.12
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• pp.1664-1672
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• 2013

In Salmonella enterica serovar Typhimurium, many genes encoded within Salmonella pathogenicity island 1 (SPI1) are required to induce intestinal/diarrheal disease. In this study, we compared the expression of four SPI1 genes (hilA, invF, prgH, and sipC) under shaking and standing culture conditions and found that the expression of these genes was highest during the transition from the exponential to stationary phase under shaking conditions. To identify regulators associated with the stationary phase-dependent activation of SPI1, the effects of selected regulatory genes, including relA/spoT (ppGpp), luxS, ihfB, hfq, and arcA, on the expression of hilA and invF were compared under shaking conditions. Mutations in the hfq and arcA genes caused a reduction in hilA and invF expression (more than 2-fold) in the early stationary phase only, whereas the lack of ppGpp and IHF decreased hilA and invF gene expression during the entire stationary phase. We also found that hfq and arcA mutations caused a reduction of hilD expression upon entry into the stationary phase under shaking culture conditions. Taken together, these results suggest that Hfq and ArcA regulate the hilD promoter, causing an accumulation of HilD, which can trigger a stationary phase-dependent activation of SPI1 genes under shaking culture conditions.

• Journal of Astronomy and Space Sciences
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• v.26 no.1
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• pp.99-110
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• 2009

The main purpose of the current research is to developments a real-time Hardware In-the-Loop (HIL) simulation testbed for the satellite formation flying navigation and orbit control. The HIL simulation testbed is integrated for demonstrations and evaluations of navigation and orbit control algorithms. The HIL simulation testbed is composed of Environment computer, GPS simulator, Flight computer and Visualization computer system. GPS measurements are generated by a SPIRENT GSS6560 multi-channel RF simulator to produce pseudorange, carrier phase measurements. The measurement date are transferred to Satrec Intiative space borne GPS receiver and exchanged by the flight computer system and subsequently processed in a navigation filter to generate relative or absolute state estimates. These results are fed into control algorithm to generate orbit controls required to maintain the formation. These maneuvers are informed to environment computer system to build a close simulation loop. In this paper, the overall design of the HIL simulation testbed for the satellite formation flying navigation and control is presented. Each component of the testbed is then described. Finally, a LEO formation navigation and control simulation is demonstrated by using virtual scenario.

• 한국정보디스플레이학회:학술대회논문집
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• 2005.07b
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• pp.1619-1622
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• 2005

The ultra thin hole injection layer (HIL) was deposited on an indium-tin-oxide (ITO) anode by using an ion beam assisted d eposition (IBAD) for the fabrication of an polymeric electroluminescence device for the first time. The device with the HIL deposited by IBAD has higher external quantum efficiency than the device with the HIL by conventional thermal evaporation. It is found that the deposited HIL by IBAD has high surface coverage on ITO anode in a few nm regions because the HIL prepared has high adatom mobility by ion beam energy.

• Proceedings of the Korea Information Processing Society Conference
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• 2019.05a
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• pp.342-345
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• 2019

드론의 동작 검증을 위한 테스트는 최종적으로 드론이 운용될 환경에서 이루어진다. 그러나 테스트 비용이 크고 테스트 비행 중 파손의 위험이 있기 때문에 시뮬레이션을 통한 사전 검증을 수행하는 것이 중요하다. 시뮬레이션은 SIL 방식이나 HIL 방식으로 이루어지는데 추가적인 외부 센서를 활용하는 경우 검증하기가 어렵다. SIL에서는 검증을 위해 가상의 외부 센서 구현이 필요하다. HIL 에서는 실제 센서를 사용하므로 가상의 외부 센서 구현은 필요 없다. 그러나 테스트 환경이기 때문에 실제 환경과 비슷한 데이터나 동작 검증에 적합한 데이터를 얻기 어렵다. 이러한 HIL에서의 문제를 해결하기 위해 외부 센서를 실제 환경에서 사용한 로그나 테스트 환경에서 센서 검증에 사용한 로그를 이용할 수 있다. 본 논문에서 제안하는 외부 센서의 로그를 활용한 HIL 시뮬레이션 기법 확장 내용은 외부 센서 데이터 입력기가 로그로부터 얻은 센서 데이터를 비행 컨트롤러로 보내 검증을 수행하기 때문에 데이터를 재사용할 수 있고 테스트 비용을 줄일 수 있다. 또 외부 센서 데이터 입력기는 로그 파서, 뷰어, 슬라이서, 데이터 전송기로 구성되어 로그로부터 검증에 적합한 데이터를 쉽게 얻어 활용할 수 있다.

• Food Science and Biotechnology
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• v.16 no.5
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• pp.778-782
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• 2007

This study assessed the effects of the antimicrobial substances sulforaphane, grapefruit seed extracts (GSE), and reuterin on the expression of Salmonella HilA and InvF virulence gene using a LacZY assay (${\beta}$-galactosidase assay) with hilA:lacZY and invF:lacZY fusion strains of Salmonella typhimurium SL1344. Salmonella was grown for 8 hr at $37^{\circ}C$ in the presence of diluted antimicrobial substances ($2\;{\mu}g/mL$ sulforaphane, $20\{\mu}g/mL$ GSE, and 0.26 mM reuterin) at concentrations that did not inhibit the cellular growth of Salmonella. Sulforaphane inhibited the expression of HilA and InvF by 50-90 and 20-80%, respectively. GSE also inhibited the expression of both genes, but to a lesser degree. Among the 3 antimicrobial substances, reuterin showed the least inhibition, which was abolished after 3-4 hr. None of the antimicrobial substances inhibited the ${\beta}$-galactosidase enzyme activity of S. typhimurium. The assay used in this study represents a very sensitive method for screening bioactive substances that inhibit the expression of virulence genes in Salmonella.

• Journal of Electrical Engineering and Technology
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• v.8 no.5
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• pp.1227-1233
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• 2013

The new engineering challenges lead to a control of a vehicle more and more complex. To tackle this issue, Hardware-In-the-Loop (HIL) simulation is used in the development of real-time embedded systems. In this paper, the control of a double parallel hybrid vehicle is validated using a reduced power HIL simulation. A graphical description is used in order to organize the emulation and control. Some experimental results of a versatile testbed are given for the Peugeot $3{\infty}8$ HYbrid4.

• Molecules and Cells
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• v.38 no.1
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• pp.1-13
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• 2015

Recent technical developments have transformed how neuroscientists can probe brain function. What was once thought to be difficult and perhaps impossible, stimulating a single set of long range inputs among many, is now relatively straight-forward using optogenetic approaches. This has provided an avalanche of data demonstrating causal roles for circuits in a variety of behaviors. However, despite the critical role that neuropeptide signaling plays in the regulation of behavior and physiology of the brain, there have been remarkably few studies demonstrating how peptide release is causally linked to behaviors. This is likely due to both the different time scale by which peptides act on and the modulatory nature of their actions. For example, while glutamate release can effectively transmit information between synapses in milliseconds, peptide release is potentially slower [See the excellent review by Van Den Pol on the time scales and mechanisms of release (van den Pol, 2012)] and it can only tune the existing signals via modulation. And while there have been some studies exploring mechanisms of release, it is still not as clearly known what is required for efficient peptide release. Furthermore, this analysis could be complicated by the fact that there are multiple peptides released, some of which may act in contrast. Despite these limitations, there are a number of groups making progress in this area. The goal of this review is to explore the role of peptide signaling in one specific structure, the bed nucleus of the stria terminalis, that has proven to be a fertile ground for peptide action.

• Journal of Microbiology and Biotechnology
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• v.15 no.1
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• pp.175-182
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• 2005

Abstract Salmonella pathogenicity island 1 (SPI1) gene expression is regulated by many environmental signals such as oxygen, osmolarity, and pH. Here, we examined changes in the expression level of various regulatory proteins encoded within SPI1 in response to three different concentrations of NaCl, using primer extension analysis. Transcription of all the regulatory genes tested was activated most when Salmonella were grown in Luria Broth (LB) containing 0.17 M NaCl. The expression of hilA, invF, and hilD was decreased in the presence of 0.47 M NaCl or in the absence of NaCl, while hilC expression was almost constant regardless of the NaCl concentration when Salmonella were grown to exponential phase under low-oxygen condition. The reduced expression of hilA, invF, and hilD resulted in lower invasion of hilC mutant to the cultured animal cells when the mutant was grown in the presence of 0.47 M NaCl or in the absence of NaCl prior to infection. Among the proteins secreted via the SPI1-type III secretion system (TTSS), the level of sopE2 expression was not influenced by medium osmolarity. Various effects of osmolarity on virulence gene regulation observed in this study is one example of multiple regulatory pathways used by Salmonella to cause infection.