• International conference on construction engineering and project management
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• 2022.06a
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• pp.937-944
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• 2022

Electric vehicles (EVs) have been growing to reduce energy consumption and greenhouse gas (GHG) emissions in the transportation sector. The increasing number of EVs requires adequate recharging infrastructure, and at the same time, adopts low- or zero-emission electricity production because the GHG emissions are highly dependent on primary sources of electricity production. Although previous research has studied solar photovoltaic (PV) -integrated EV charging stations, it is challenging to optimize spatial areas between where the charging stations are required and where the renewable energy sources (i.e., solar photovoltaic (PV)) are accessible. Therefore, the primary objective of this research is to support decisions of siting EV charging stations using a spatial data clustering method integrated with Geographic Information System (GIS). This research explores spatial relationships of PV power outputs (i.e., supply) and traffic flow (i.e., demand) and tests a community in the state of Indiana, USA for optimal sitting of EV charging stations. Under the assumption that EV charging stations should be placed where the potential electricity production and traffic flow are high to match supply and demand, this research identified three areas for installing EV charging stations powered by rooftop PV in the study area. The proposed strategies will drive the transition of existing energy infrastructure into decentralized power systems. This research will ultimately contribute to enhancing economic efficiency and environmental sustainability by enabling significant reductions in electricity distribution loss and GHG emissions driven by transportation energy.

• Current Optics and Photonics
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• v.7 no.5
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• pp.485-495
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• 2023

The pixel size in high-resolution complementary metal-oxide-semiconductor (CMOS) image sensors continues to shrink due to chip size limitations. However, the pixel pitch's miniaturization causes deterioration of optical performance. As one solution, a quad color filter (CF) array with pixel binning has been developed to enhance sensitivity. For high sensitivity, the microlens structure also needs to be optimized as the CF arrays change. In this paper, the covered microlens, which consist of four microlenses covered by one large microlens, are proposed for the quad CF array in the backside illumination pixel structure. To evaluate the optical performance, the suggested microlens structure was simulated from 0.5 ㎛ to 1.0 ㎛ pixels at the center and edge of the sensors. Moreover, all pixel structures were compared with and without in-pixel deep trench isolation (DTI), which works to distribute incident light uniformly into each photodiode. The suggested structure was evaluated with an optical simulation using the finite-difference time-domain method for numerical analysis of the optical characteristics. Compared to the conventional microlens, the suggested microlens show 29.1% and 33.9% maximum enhancement of sensitivity at the center and edge of the sensor, respectively. Therefore, the covered microlens demonstrated the highly sensitive image sensor with a quad CF array.

• Molecules and Cells
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• v.47 no.2
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• pp.100031.1-100031.13
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• 2024

It is now well-accepted that obesity-induced inflammation plays an important role in the development of insulin resistance and type 2 diabetes. A key source of the inflammation is the murine epididymal and human visceral adipose tissue. The current paradigm is that obesity activates multiple proinflammatory immune cell types in adipose tissue, including adipose-tissue macrophages (ATMs), T Helper 1 (Th1) T cells, and natural killer (NK) cells, while concomitantly suppressing anti-inflammatory immune cells such as T Helper 2 (Th2) T cells and regulatory T cells (Tregs). A key feature of the current paradigm is that obesity induces the anti-inflammatory M2 ATMs in lean adipose tissue to polarize into proinflammatory M1 ATMs. However, recent single-cell transcriptomics studies suggest that the story is much more complex. Here we describe the single-cell genomics technologies that have been developed recently and the emerging results from studies using these technologies. While further studies are needed, it is clear that ATMs are highly heterogeneous. Moreover, while a variety of ATM clusters with quite distinct features have been found to be expanded by obesity, none truly resemble classical M1 ATMs. It is likely that single-cell transcriptomics technology will further revolutionize the field, thereby promoting our understanding of ATMs, adipose-tissue inflammation, and insulin resistance and accelerating the development of therapies for type 2 diabetes.

• Journal of the Korean Association of Geographic Information Studies
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• v.17 no.4
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• pp.28-39
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• 2014

Several studies have been performed globally on the construction of integrated systems that are available for the integrated use of 3D geographic information on terrain and oceans. Research on 3D geographic modeling is also facilitated by the application of Lidar surveying, which enables the highly accurate realization of 3D geographic information for a wide area of land. In addition, a few marine research organizations have been conducting investigations and surveying diverse ocean information for building and applying MGIS(Marine Geographic Information System). However, the construction of integrated geographic information systems for both terrain and oceans has certain limitations resulting from the inconsistency in reference systems and datum levels between two data. Therefore, in this investigation, integrated geospatial information has been realized by using a combined topographical map, after matching the reference systems and datum levels by integration of airborne Lidar data and multi-beam echo sounder data. To verify the accuracy of the integrated geospatial information data, ten randomly selected samples from study areas were selected and analyzed. The results show that the 10 analyzed data samples have an RMSE of 0.46m, which meets the IHO standard(0.5m) for depth accuracy of hydrographic surveys.

• The Journal of Internal Korean Medicine
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• v.44 no.3
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• pp.366-386
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• 2023

Objective: In this study, a questionnaire survey was conducted for doctors and patients to obtain basic data necessary for the development of an integrated medical system for idiopathic pulmonary fibrosis (IPF). Methods: Questionnaires were developed separately for doctors and patients through an expert group meeting. The survey subjects were recruited online and offline, and finally, responses from 231 doctors and 59 patients were used for statistical analysis. Results: The most important parts in the treatment of IPF for both doctors and patients were the "improvement of respiratory symptoms," "improvement of quality of life," and "prevention of disease progression." Antifibrotic agents were prescribed at a high rate, and 100% of the specialists in Western medicine (WM) and 45.8% of patients reported experiencing side effects. As for the additional payment costs that patients considered as affordable for an integrated medical system, "under 50,000 won (about 38$)" was reported the most in both doctor and patient groups. With regard to the reasons for their reluctance to recommend an integrated medical system for IPF, specialists in WM responded highly to "uncertain evidence for treatment effectiveness." Regarding complementary and alternative medicine therapies that can be beneficial in patients with IPF, "lifestyle management," "diet management," "herb," "relaxation therapy," and "psychotherapy" were ranked high in both doctor and patient groups. Conclusions: In this study, a questionnaire survey on IPF was conducted to review actual treatment status, analyze shortcomings, and identify considerations for the development of an integrated medical system for IPF in the future.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.9
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• pp.279-286
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• 2012

Recently, design of Universal Soft Controller(USC) has been applied to the advanced control room for nuclear power plant. USC is software-based manual control means to control safety components as well as non-safety components in the highly-integrated control room. Therefore, design feature of USC is essential for the implementation of a single workstation in the advanced control room. The traditional control room is replaced by computer-driven consolidated operator interfaces. Considering our design has further reduced the probability of USC spurious signals by requiring two distinct operator control actions to generate any control signal. The reality of USC does not increase the probability of reactor trip because the probability of spurious USC signal is negligible. Universal Soft Control represents a significant evolution in nuclear I&C/HSI System. USC integrates the indicators and controls from multiple divisions into a single integrated visual display unit(VDU) based HSI(Human System Interface). In order to prevent adverse influence on safety function performance from USC failure, ESFAS signals are applied to safety components or functions. In addition, safety manual switches have priority over USC's signals. Therefore, spurious USC signals can be momentarily blocked by selecting a soft control command from the safety VDU.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.420-422
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• 2005

TMC (Tautomycetin) is a liner polyketide immunosuppressive antifungal compound produced by Streptomyces spp. Inhibition of T cell proliferation with TMC was observed highly efficient at 100-fold lower than those needed to achieve maximal inhibition with cyclosporin A. To elucidate the biosynthetic pathway of TMC, a genomic DNA library was constructed using a E. coil-Streptomyces shuttle cosmid vector, pOJ446. The DNA libraries were screened by colony blot hybridization using several polyketide ${\beta}-ketosynthase$ (KS) probes amplified from TMC-producing Streptomyces genomic DNA using polymerase chain reaction (PCR), of which the degenerate primers were designed based on the highly conserved sequences present in KS domains of various type I polyketide synthase genes in Streptomyces species. This library construction and screening approach led to the isolation of several positive cosmid clones representing type I polyketide biosynthetic gene clusters. In addition, a Streptomyces regulatory gene called afsR2 (a global regulatory gene stimulating antibiotic production in both S. coelicolor and S. lividans) was successfully integrated into the TMC-producing Streptomyces chromosome via E. coil-Streptomyces heterologous conjugation mehtod. The more detailed results of production improvement and genetic characterization of TMC-producing Streptomyces spp. will be discussed.

• Journal of Korean Clinical Health Science
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• v.4 no.1
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• pp.504-509
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• 2016

Purpose. This study aims to present basic data to develop programs suitable to the characteristics of elderly people through a meta-analysis of effectiveness of variables related to psychological effects of programs of elderly people conducted in past 15 years. Methods. The analysis subjects are total 229 articles related to the psychological effects of programs for elderly people and submitted for master or doctor degrees or published in academic journals. CMA2 is used for the analysis. Results. The results of this study shows lower variables of the psychological effect promoting factor group that are highly effective for Life Satisfaction, Self-Efficacy, Self-Respect and Self-Integration and lower variables of suppressing factor group that are highly effective for Loneliness, Tension, Weakness, Anger and Depression. For the effect scale of psychological effect promoting factors, Arts is shown to be the highest followed by Exercise, Consultation, Recollection, Others and Recreation in order. For the effect scale of suppressing factors, Consultation is shown to be the highest followed by Recollection, Arts, Exercise, Others and Recreation) in order. Conclusions. This study has its own meaning for establishing integrated factors of psychological effects of programs for elderly people and presenting realistic data for planing programs suitable for various desires of elderly people.

• Journal of Advanced Navigation Technology
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• v.13 no.5
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• pp.699-704
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• 2009

The requirements of disaster prevention have been constantly increasing on highly disaster frequency by Global warming and environmental destruction. The damage occur more highly, especially when it's on the localized change of weather. It requires that we have methods of disaster prevention locally. In this paper, we design and implement a breakwater disaster prevention system integrated wireless sensor technique for the shore breakwater of East Sea that is raised anxiety about an accident occurrence due to stormy weather. The provided disaster prevention system perceive the seriousness of the situation that is chance of that happening by the information of realtime remote situation and a prediction system so that it could be of some help to reduce the damage of disaster and the cost of recovery.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.813-815
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• 2008

We prepared highly transparent and conductive Oxide/Metal/Oxide(OMO) multilayer by sputtering and developed wet etching process of OMO with a clear edge shape for the first time. The transmittance and sheet-resistance of the OMO are about 89% and $3.3\;{\Omega}/sq.$, respectively. We adopted OMO as a gate electrode of transparent TFT (TTFT) array and integrated OLED on top of the TTFT to result in high aperture ratio of bottom emission AM-OLED.