• Title/Summary/Keyword: high-school biology

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Full Length cDNA, Genomic Organizations and Expression Profiles of the Porcine Proteasomal ATPases PSMC5 Gene

  • Wang, Y.F.;Yu, M.;Liu, B.;Fan, B.;Wang, H.;Zhu, M.J.;Li, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.7
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    • pp.897-902
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    • 2004
  • PSMC5 subunit, which belongs to the 26S proteasomal subunit family, plays an important role in the antigen presentation mediated by MHC class I molecular. Full-length cDNA of porcine PSMC5 was isolated using the in silico cloning and rapid amplification of cDNA ends (RACE). Amino acid was deduced and the primary structure was analyzed. Results revealed that the porcine PSMC5 gene shares the high degree of sequence similarity with its mammalian counterparts at both the nucleotide level and the amino acid level. The RT-PCR was performed to detect the porcine PSMC5 expression pattern in seven tissues and the result showed that high express level was observed in spleen, lung, marrow and liver while the low express level was in muscle. The full-length genomic DNA sequence of porcine PSMC5 gene was amplified by PCR and the genomic structure revealed that this gene was comprised by 12 exons and 11 introns. Best alignment of the cDNA and genomic exon DNA sequence presents 4 mismatches and this information potentially bears further study in gene polymorphisms.

The Analysis of Bioinformatics and Biotechnology Contents in Curriculum and Textbooks According to Revising Curricula (교육과정 개정에 따른 교과서와 교육과정 속의 생명공학과 생물정보학 내용 분석)

  • Ju, Hee-young;Dong, Hyo-kwan;Lee, Kil-jae
    • Journal of Science Education
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    • v.36 no.2
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    • pp.186-197
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    • 2012
  • The proliferation of bioinformatics in modern biology marks a modern revolution in science that promises to influence science education at all levels. This study analyzed the contents of standards in the 7th and 2007 and 2009 revised high school biology curricula and compared the contents, amount and the presentation styles of bioinformatics with those of biotechnology in biology textbooks. In result, first of all, there are some vague expressions about biotechnology and bioinformatics in the 7th and 2007 revised curriculum. There is a clear expression about biotechnology in 'life science I' and 'advanced biology' of 2009 revised curriculum. Second, more biotechnology is introduced than bioinformatics in 'science', 'biology I', 'biology II', 'life science I' textbooks. Third, in 'biology for high class' textbook, amount of biotechnology contents in the 2007 revised curriculum didn't increase. An more effort to introduce bioinformatics to science high school student is needed according to revising curricula.

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An Analytical Study of the Exhibits in the Section of Biology in the National Science Fairs (전국과학전람회 생물부문 출품작 분석)

  • 최도성
    • Journal of Korean Elementary Science Education
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    • v.22 no.1
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    • pp.97-108
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    • 2003
  • The total 4,895 works presented at Science Fairs for the past 17 years(1986∼2002) are classified by subjects and participators, and the 1,277 works in biology section are analyzed by participators, contents, and object materials. The results are as follows: The proportion of exhibits according to sections was the most in Biology(26.1%). The social position of exhibitors and its proportion were 45.7% in students and 54.3% in teachers and popular people. The proportions of students' exhibits by the level of school were elementary school(68.3%). middle school(14.3%), and high school(17.4%). This indicates rapid decrease in the number of exhibits in middle and high schools. The proportion of students' exhibits(55.9%) is higher than that of teachers' exhibits(44.1%) in the section of Biology. In terms of contents, exhibits about Physiology and Ecology were the most(67.6%). The materials used in those exhibits and the proportion were Animalia(50.9%), Plantae(39.9%), Fungi(5.7%), Monera(1.8%), and Protista(1.7%). The proportion of taxa in plants studied in the exhibits were Dicotyledoneae(65.9%) and Monocotyledoneae(17.3%). The proportion of taxa In animals was Arthropoda(60.2%), Vertebrata(24.9%), and Mollusca(11.1%). The species used in those exhibits and its times were pine tree(11 times), dandelion(10 times), and butterfly(11 times).

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The Vegetation of Mt. Choksang (赤裳山의 植生)

  • Kim, Chang-Hwan;Seon-Hee Kang;Bong-Seop Kil
    • The Korean Journal of Ecology
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    • v.14 no.2
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    • pp.137-148
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    • 1991
  • The forest vegation and their structural characteristics in mt. chokang were investgated by phytosociological survey and ordination. It was classified five forests such as quercus tschonoskii community and fraxinus mandshurica community and this result has confirmed to coincide with community ciassification by polar ordination. Chang of diversity index was shown to decase, whereas dominance index, to increase according to chang high altitude. By soil moisture gradient, distribution pattern of fraxinus mandshurica, acer mono, carpinus cordata was in moist, but quercus serrata,˘quercus variabilis and mongolica, dry habitats.

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ErbB3 binding protein 1 contributes to adult hippocampal neurogenesis by modulating Bmp4 and Ascl1 signaling

  • Youngkwan Kim;Hyo Rim Ko;Inwoo Hwang;Jee-Yin Ahn
    • BMB Reports
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    • v.57 no.4
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    • pp.182-187
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    • 2024
  • Neural stem cells (NSCs) in the adult hippocampus divide infrequently; the endogenous molecules modulating adult hippocampal neurogenesis (AHN) remain largely unknown. Here, we show that ErbB3 binding protein 1 (Ebp1), which plays important roles in embryonic neurodevelopment, acts as an essential modulator of adult neurogenic factors. In vivo analysis of Ebp1 neuron depletion mice showed impaired AHN with a low number of hippocampal NSCs and neuroblasts. Ebp1 leads to transcriptional repression of Bmp4 and suppression of Ascl1 promoter methylation in the dentate gyrus of the adult hippocampus reflecting an unusually high level of Bmp4 and low Ascl1 level in neurons of Ebp1-deficient mice. Therefore, our findings suggests that Ebp1 could act as an endogenous modulator of the interplay between Bmp4 and Ascl1/Notch signaling, contributing to AHN.

Crystal structure of the pretense domain of an ATP-independent heat shock protease HtrA

  • Kim, Dong-Young;Kim, Dong-Ryoung;Ha, Sung-Chul;Neratur K.Lokanath;Hwang, Hye-Yeon;Kim, Kyeong-Kyu
    • Proceedings of the Korea Crystallographic Association Conference
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    • 2002.11a
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    • pp.24-24
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    • 2002
  • HtrA (high temperature requirement A), a periplasmic heat shock protein, is known to have molecular chaperone function at low temperatures and proteolytic activity at elevated temperatures. To investigate the mechanism of functional switch to pretense, we have determined the crystal structure of the N-terminal protease domain (PD) of HtrA from Thermotoga maritima. HtrA PD shares the same fold with chymotrypsin-like serine professes. However, crystal structure suggests that HtrA PD is not an active pretense at current state since its active site is not formed properly and blocked by an additional helical lid. On the surface of the lid, HtrA PD has hydrophobic patches that could be potential substrate binding sites for molecular chaperone activity. Present structure suggests that the activation of the proteolytic function of HtrA PD at elevated temperatures might occur by the conformational change.

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