• 비만대사연구학술지
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• 제2권1호
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• pp.29-35
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• 2023

Familial hypercholesterolemia (FH) is a genetic disease that is not well known or diagnosed in Korea. This disease is associated with persistently high levels of low-density lipoprotein cholesterol (LDL-C), which increase the risk of coronary artery disease at a young age. Therefore, early diagnosis and treatment are important; however, there are no global consensus diagnostic criteria. In Korea, the Dutch Lipid Clinic Network diagnostic criteria, and the Simon Broome diagnostic criteria were used for diagnosis of FH according to the agreement announced at the Korean Society of Lipid and Atherosclerosis (KSoLA) in 2022. Recently, the absence of coronary artery calcification has been considered a good prognostic factor, even among patients with very high LDL-C levels who are considered to be at high risk for atherosclerotic cardiovascular disease. We describe throughout this paper the diagnosis and treatment of FH in a young male without coronary artery calcification.

• 한국산학기술학회논문지
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• 제19권4호
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• pp.423-432
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• 2018

이 연구는 40-59세의 중년들이 갖고 있는 여러 가지 건강행태 중에서 고밀도지단백(HDL) 콜레스테롤에 영향을 명확히 미치는 건강행태를 파악함으로써 한국 중년의 건강증진에 도움이 되는 기초자료를 제공되고자 한다. 국민건강영양조사의 제4기 3차년도(2009), 제5기의 1차년도(2010), 2차년도(2011), 3차년도(2012), 제6기의 1차년도(2013) 등 총 5개년의 원시데이터를 합하여 사용하여 7,406명을 최종분석 대상자로 선정하였다. 고밀도지단백 콜레스테롤을 40mg/dl 미만과 40mg/dl 이상으로 두 집단으로 구분했다. 다중 로지스틱 회귀분석을 시행한 결과, 여자보다 남자일 경우 OR=3.916배, 비만 유병이 저체중에서 정상일 경우 OR=3.439배, 비만일 경우 OR=7.336배, 음주자일 때 OR=1.629배, 흡연자일 때 OR=1.498배, 중등도 신체활동 미실천일 시 OR=1.426배, 걷기 미실천일 시 OR=1.264배, 탄수화물을 과소 섭취할 때보다 적정 섭취할 때 OR=1.510배, 과다 섭취할 때 OR=1.787배 고밀도지단백(HDL) 콜레스테롤이 40mg/dl 이상에서 40mg/dl 미만으로 될 확률이 증가하였다. 한국 중년의 고밀도지단백(HDL) 콜레스테롤 수치를 높여 적절한 건강을 유지하기 위해서는 유산소 운동, 금연, 절절한 음주, 비만 해소, 건강한 식습관과 건강한 식품 선택으로 인한 외식이 이루어져야 한다. 이를 위해서는 지역사회 내에서 지속적인 홍보와 교육이 필요하며, 건강행태를 생활 속에서 실천할 수 있도록 하는 사회적 환경이 구축되어야 할 것이다.

• 한국식품영양과학회지
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• 제25권3호
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• pp.433-440
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• 1996

To assess the relationship between serum cholesterol level and dietary intake in obese children, 50 subjects were selected as an obese group and 50 subjects as a normal group depending upon body mass index. Fasting blood samples were obtained and analyzed for serum total cholesterol(TC), high density lipoprotein cholesterol(HDLC), low density lipoprotein cholesterol(LDLC) and triglyceride(TG). The dietary intake and information on dietary behavior and family environment were obtained by questionaire using 24 hour dietary recall method for 2-consecutive days. The concentrations of TC, LDLC, HDLC and TG of obese group were estimated to be 193.3mg/dl, 122.5mg/dl, 53.7mg/dl and 86.0mg/dl, respectively. The obese group showed higher TC, LDLC, TG level(p<0.001) and lower HDLC level(p<0.001) than normal group. Food intakes in obese group were similar to those of normal group except meats & fishes(P<0.01), milk & dairy products, fruits(p<0.05), and green & yellow vegetables(p<0.001). Nutrient intakes in obese group exceeded Korean recommended dietary allowance for the corresponding ages. Saturated fatty acid(p<0.05) and cholesterol(p<0.001) intakes in obese group were higher than those of normal group. In correlation analysis, meats & fishes, eggs and milk & dairy products intakes were positively related to serum TC, LDLC and TG ; on the contrary, green & yellow vegetables and fruits intakes were negatively related to serum TC, LDLC and TG ; but positively to HDLC. Obesity index, serum cholesterol level, cholesterol and saturated fatty acid intake were positively correlated with parent's obesity index, frequency of snack per day, eating rate and late snack.

• Asian-Australasian Journal of Animal Sciences
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• 제29권10호
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• pp.1458-1463
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• 2016

A 42-d study with 384 Hy-line brown laying hens was conducted to assess the effects of dietary octacosanol supplementation on laying performance, egg quality and blood metabolites of laying hens. Hens were randomly allocated into 4 dietary groups of 8 cages each, which were fed basal diet supplemented with 0 (Control), 9 (OCT9), 18 (OCT18), and 27 (OCT27) mg/kg diet of octacosanol isolated from rice bran, respectively. The experiment was conducted in an environmental controlled house and hens were fed twice daily for ad libitum intake. Laying performance was determined over the 42-d period, and egg quality as well as blood metabolites were estimated on d 21 and d 42. Diets in OCT18 and OCT27 increased (p<0.05) laying rate, egg weight, egg mass, egg albumen height, Haugh unit and eggshell strength on d 42, but decreased (p<0.05) feed conversion rate and levels of total cholesterol, triglyceride and low density lipoprotein cholesterol in the serum as compared to those of Control. Feed intake, yolk color, yolk diameter, eggshell thickness and high density lipoprotein cholesterol were similar (p>0.05) among treatments. Results demonstrate that supplementing 18 to 27 mg/kg diet of rice bran octacosanol can improve laying rate and egg quality and reduce blood lipid of laying hens.

• 대한정형도수물리치료학회지
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• 제21권2호
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• pp.7-14
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• 2015

Purpose: The purpose of this study was to investigate the effects of falls prevention exercise program to balance, falls efficacy, blood pressure and blood lipids in the elderly females. Methods: A total of twenty-six elderly women participated in this study. All subjects participated in exercise program based on pelvic stabilization and balance training on two times a week for twelve weeks. They were measured about Berg balance scale (BBS), Time up and go (TUG), Functional reach test (FRT), Sit to stand (STS) for balance, falls efficacy scale-international (FES-I) for falls efficacy, systolic blood pressure (SBp), diastolic pressure (DSp) for blood pressure, and total cholesterol (TC), triglyseride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) for blood lipids. Results: There were significant improvements of BBS (p<.05), TUG (p<.001) FRT (p<.01), and STS (p<.001) in the balance after exercise program. There was significant improvements in FES-I (p<.001) in the falls efficacy, There were no statistical differences of SBp and DSp in the blood pressure. There were no statistical differences of TC, TG, HDL-C, and LDL-C in the blood lipids. Conclusions: Falls prevention exercise program was meaningful increasing balance ability and falls efficacy.

• Journal of Korean Biological Nursing Science
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• 제19권1호
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• pp.1-10
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• 2017

Purpose: The purpose of this study was to investigate influences of drinking, smoking, and obesity indices on cardio-cerebrovascular disease risk factors in Korean young men. Methods: The subjects were 234 young men, aged 20 to 39 years. Body mass index (BMI), percent body fat (PBF), body fat mass (kg), and waist hip ratio (WHR) were measured as obesity indices. Systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood sugar (FBS), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were measured as cardio-cerebrovascular disease risk factors. The data were analyzed by t-test, ANOVA, Pearson's correlation coefficient, and multiple regression analysis using SAS 9.4. Results: Statistically significant factors were BMI for SEP; age, degree of drinking, body fat mass for DBP; WHR for TC; WHR and age for TG; age, degree of smoking and PBF for HDL-C; WHR, age and degree of smoking for LDL-C. Conclusion: Factors identified in this study need to be considered in cardio-cerebrovascular disease prevention programs for young men.

• 대한간호학회지
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• 제34권5호
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• pp.739-750
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• 2004

Purpose: This study was to evaluate the effects of foot reflexology on blood pressure, serum lipids level and life satisfaction in essential hypertension patients. Method: The research design used was a nonequivalent control group pretest-posttest design. Foot Reflexology was used as the experimental treatment from June 23rd, 2003 until August 31st, 2003. Thirty-four subjects were assigned to an experimental group(18) and control group(16). Foot Reflexology was administered twice a week for 6 weeks and self foot Reflexology was administered twice a week for 4 weeks on the experimental group. Result: There was a significant decrease in systolic blood pressure but no significant decrease indiastolic pressure in the experimental group compared to the control group. The total cholesterol level in the experimental group compared to the control group was not significantly decreased after foot reflexology. However, the triglyceride level in theexperimental group compared to the control group was significantly decreased after foot reflexology. On the other hand, high density lipoprotein and low density lipoprotein levels in the experimental group compared to the control group was not significantly decreased after foot reflexology. Life satisfaction in the experimental group compared to the control group was significantly improved after foot reflexology. Conclusion: The results proved that foot reflexology was an effective nursing intervention to decrease systolic pressure, and triglyceride but not for the blood cholesterol and to improve life satisfaction. Therefore, blood cholesterol should be further evaluated in a larger group of subjects and for a longer period. Further research is regarded as necessary to evaluate and to compareeffects of self-foot reflexology and foot reflexology.

• 대한간호학회지
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• 제46권2호
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• pp.249-259
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• 2016

Purpose: The purpose of this study was to examine the effects of auricular acupressure on reducing obesity in adult women with abdominal obesity. Methods: The study design was a non-equivalent control group pretest-posttest design. Participants were 58 women, aged 20 years or older, assigned to the experimental group (n=30) or control group (n=28). Auricular acupressure using vaccaria seeds was administered to the experimental group. The sessions continued for 8 weeks. Outcome measures included body weight, abdominal circumference, and body mass index, body fat mass, body fat percentage, triglyceride, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, and serum glucose. Results: Women in the experimental group showed significant decreases in body weight (t=6.19, p<.001), abdominal circumference (t=4.01, p<.001), and body mass index (t=2.58, p=.006) after 8 weeks compared with those in the control group. Conclusion: Results show that auricular acupressure using vaccaria seeds was effective in decreasing body weight, abdominal circumference, body mass index, and triglyceride levels in adult women with abdominal obesity.

• 한국콘텐츠학회논문지
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• 제5권2호
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• pp.177-185
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• 2005

본 연구는 중년남성 10명을 대상으로 준비운동, 저항운동, 수중운동 그리고 정리운동 순으로 구성된 복합운동프로그램을 1일 60분씩 주 4회의 빈도로 12주간 실시하여 대상자들의 실험전과 후의 변인들을 비교, 분석한 결과 신체구성 성분인 체지방율, 제지방량, 신체질량지수는 각각 유의하게 감소(p<.01)하였으며, 건강관련 체력은 근력, 근지구력, 유연성에서 유의하게 증가(p<.01)하였다. 또한, 혈중지질의 경우 총 콜레스테롤, 저밀도지단백콜레스테롤, 중성지방은 유의하게 감소(p<.01)하였으며, 고밀도지단백콜레스테롤은 유의하게 증가(p<.05)하였다.

• 대한물리의학회지
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• 제8권2호
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• pp.239-243
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• 2013

PURPOSE: The purpose of present study was to investigate effects of obesity, blood pressure and life style on lipid indices and blood pressure in men of age 40s. METHODS: One hundred forty five subjects in men of age 40s were participated in this study. All participants were taken physical examination, lifestyle survey and laboratory test. According to examination, participants were divided into two group in four categories ; obesity and normal group, hypertension and normal group, smokers and non-smokers, and drinkers and non-drinkers. The low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), total cholesterol (TC), triglyceride (TG), systolic blood pressure (SBP), diastolic blood pressure (DBP) were analyzed by independent t-test for comparison between two groups. RESULTS: The values of LDL, TC, SBP, DBP were higher and HDL was lower in obesity than in normal group (p<.05). The values of LDL, TC, SBP, DBP were higher in hypertension group than in normal group (p<.05). The values of TG was higher and HDL was lower in smokers than in non-smokers (p<.05). There's no significant differences between drinkers and non-drinkers (p>.05). CONCLUSION: It can be seen that obesity and blood pressure were more relative risk factors than smoking and alcohol indices in cardiovascular diseases.