• Title/Summary/Keyword: high-calcium

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High dose vitamin D injection induced severe hypercalcemia (비타민 D 고용량 주사로 인한 심한 고칼슘혈증 발생 1예)

  • Lee, Sang Ah;Moon, Jae Cheol
    • Journal of Medicine and Life Science
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    • v.16 no.1
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    • pp.31-33
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    • 2019
  • Hypercalcemia is often seen in patients, but most of them showed mild to moderate hypercalcemia. The severe hypercalcemia with a blood calcium level of 14.0 mg/dL or more is known to be associated mainly with malignant tumors. Because this is emergency status, most clinicians tried to decrease serum calcium level to near normal range to improve symptoms related to hypercalcemia. A 71-year-old female patient visited the emergency room with dizziness and general weakness. Her serum calcium level was very high (15.6 mg/dL), but serum PTH, 25-OH vitamin D, and PTH related peptide were normal. We can exclude hyperparathyroidism, familial hypocalciuric hypercalcemia, other connective tissue diseases, and hypercalcemia due to malignant tumors as a cause of severe hypercalcemia. Conclusively, we diagnosed as severe hypercalcemia due to high-dose vitamin D injections treated one week ago. High dose vitamin D injections have recently been shown to increase the frequency of prescription as the various causes and the clinicians needed to carefully monitor the serum calcium levels in the patients after treating with high dose vitamin D.

The Cause of Calcium Deficient leaf of Burley Tobacco (Nicotiana tabacum L.) (Burley종 연초의 칼슘결핍엽 발생원인)

  • Kim, Yong-Ok;Park, Soo-June;Lee, Chul-Hwan;Choi, Jung
    • Journal of the Korean Society of Tobacco Science
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    • v.11 no.1
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    • pp.3-9
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    • 1989
  • Field experiment was conducted to find out the cause of calcium deficiency of burley tobacco (Nicotiana tabacum L.), Liming materials and application rate were CaSO4 : Ca 35kg/10a, CaCO3 : 35kg/10a and agricultural lime : Ca 142kg/10a. The breakdown in tissues at tips and margins of upper leaves was developed at maximum growth stage. If complete breakdown and death does not occur and growth takes place later, giving the leaf a scalloped appearance. Upper leaves contained lower calcium content than other leaves. The stem and midvein of calcium deficient plants contained lower calcium and calcium minus oxalic acid, but higher oxalic acid contents than those of normal plant. Fresh leaves of limed plot contained higher calcium and oxalic acid, but not significant increment of calcium minus oxalic acid than those of unlimed plot. Since calcium oxalate is insoluble, it could precipitate within the culls if the calcium and oxalic acid are accessible to each other. It suggest that high level of oxalic acid in stem and midvein could be interfering with translocation of calcium to upper leaves.

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Effect of Econazole on ATP- and Compound 48/80-Induced Histamine Release in Rat Peritoneal Mast Cells (흰쥐의 복강비만세포에서 ATP와 Compound 48/80에 의한 Histamine 유리에 미치는 Econazole의 영향)

  • 장용운;이윤혜;이승준;서무현;윤정이
    • YAKHAK HOEJI
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    • v.45 no.3
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    • pp.282-286
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    • 2001
  • To investigate the different mechanism between ATP and compound 48/80 (C$_{48}$80/)-induced histamine release, we observed effects of calcium antagonists in histamine release of rat peritoneal mast cells. Verapamil and diltiazem (voltage-dependent calcium channel blocker) and TMB-8 (a blocker of intracellular calcium release) significantly inhibited ATP-induced histamine release, but did not inhibit $C_{48}$80/-induced histamine release. Econazole (a blocker of receptor-operated calcium channel) dose-dependently inhibited both ATP and $C_{48}$80/-induced histamine release, but inhibitory effect of econazole in ATP-induced histamine release was more potent than that in $C_{48}$80/-induced histamine. EGTA dose-dependently inhibited ATP and $C_{48}$80/-induced histamine release, but $C_{48}$80/-induced histamine release was slightly inhibited by high concentrations (>2 mM) of EGTA. These results suggest that ATP-induced histamine release is related to broth intracellular calcium release and extracellular calcium influx via voltage-dependent calcium channel and receptor-operated calcium channel. $C_{48}$80/-induced histamine release is related to extracellular calcium influx, especially by receptor-operated calcium channel rather than voltage-dependent calcium channel.

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Low-dose Chest CT in Evaluation of Coronary Artery Calcification: Correlation with Coronary Artery Calcium Score CT (관상동맥 석회화 평가에서 저선량 흉부 CT와 관상동맥 석회화검사의 일치도)

  • Yon-Min Kim
    • Journal of the Korean Society of Radiology
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    • v.17 no.7
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    • pp.1033-1039
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    • 2023
  • Low-dose chest CT, which is used as a lung screening test, also includes information on coronary artery calcification within the scan range. The purpose of this study was to investigate the usefulness of determining coronary artery calcification using Low-dose chest CT. Those who underwent low-dose chest CT and coronary artery calcification score CT on the same day were eligible. Coronary artery calcium score CT results were divided into 4 groups (Low: 1〈CACS〈10, Mild: 10〈CACS〈100, Moderate: 100〈CACS〈400, High: 400〈CACS) by referring to the Coronary artery calcium score categories and risks. After selecting 30 people each group, five radiotechnologists with more than 15 years of experience in coronary artery calcium measurement retrospectively analyzed the presence or absence of coronary artery calcification in low-dose chest CT images. The results of the five observers' uniform interpretation of the low-dose chest CT image were consistent with the coronary artery calcium score CT results in Low group: 56%, Mild group: 96.6%, Moderate group: 100%, and High group: 100%. appeared. In the Low group, all 5 observers observed calcification in 17 out of 30 cases, and in 7 cases all 5 observers decided that calcification could not be identified. Coronary artery calcification could be observed in 100% of asymptomatic adults with a calcium score of 15 or higher in low-dose chest CT scans. The minimum calcium score that can be identified is 1, and it was found that even very small calcifications can be identified when the subject's body size is small or the scan is performed at a time when heart movement is minimal.

Interaction of Dietary Wheat Bran and Dietary Calcium Levels ell Calcium Utilization and Bone Mass in Post-breeding Female Rats

  • Park, Young-Sook
    • Nutritional Sciences
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    • v.1 no.1
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    • pp.16-21
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    • 1998
  • This study was conducted to determine the interaction of dietary wheat bran and dietary calcium levels n)n calcium utilization in post-breeding female rats. It was designed to compare the effects of four different levels (2.5, 5, 10 and 20%) of wheat bran and two different levels (0.5 and 1%) of calcium on bone and calcium balance in post-breeding female rats over a ten-week period. The effects of diet on animal weight gain, serum calcium, femur weight, femur calcium concentration, bone mass and calcium balance were determined and statistically analyzed. The addition of 20% wheat bran significantly (p$\leq$0.05) decreased the weight gain of rats. Serum calcium and bone calcium contents were more affected by dietary calcium level than by dietary wheat bran level. There was no significant difference in fat-free solid, ash, percentage of ash to fat-free solid and percentage of calcium to ash among groups. Groups fed the 1% calcium diet had a higher percentage of calcium to fat-free solid. All rats were in positive calcium balance during the three-4ay experimental period. The average calcium balance of the rats fed 1% calcium diet ranged from 25.34 to 53.90mg and the average calcium balance of the rats fed the 0.5% calcium diet ranged from 26.71 to 32.90mg. In rats receiving 2.5% wheat bran, the difference in calcium balance between the group fed the 1% calcium diet and the group fed the 0.5% calcium diet was only 1.37mg, which was not significantly (p$\leq$0.05) different. In rats receiving 20% wheat bran, the difference in calcium balance between the group fed the 1% calcium diet and the group fed the 0.5% calcium diet was 19.S7mg, which was significantly (p$\leq$0.05) different. The addition of wheat bran caused an increase in the calcium balance of the rats adminslesed the 1% calcium diet. On the other hand, the addition of wheat bran had no effect on the calcium balance of the rats adminislesed the 0.5% calcium diet. In conclusion, calcium utilization of rats wire more positively affected by the interaction of both dietary wheat bran levels and dietary calcium levels than either dietary wheat bran levels or dietary calcium levels alone. Moderate wheat bran consumption did not interfere with the calcium metabolism of rats when calcium intake was high enough.

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Food sources of vitamin and mineral for Korean people(I) -calcium and iron rich foods- (우리나라 국민의 비타민과 무기질 급원식품(I) -칼슘과 철분의 급원식품-)

  • 김영남;나현주;강희자
    • Journal of Korean Home Economics Education Association
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    • v.12 no.2
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    • pp.47-64
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    • 2000
  • The purpose of this study was to search the calcium and iron rich foods in Korean people. The food sources presented in the current home economics textbooks of middle and high school were investigated. And 40 kinds of calcium and iron rich foods were selected by the quantity in 100g edible portion. one serving size and according to 1997 food supply data. Also 3 major food groups of calcium and iron supply in Korean were identified, and 10 rich foods for each food groups were selected. The results were summarized as follows. 1. The food sources of calcium 1) The food sources of calcium presented in the home economics textbooks of middle and high school are milk and dairy products. small fishes such as anchovy icefish and dried strip and green vegetables etc. 2) The calcium rich foods by 100g edible portion were in order of skim milk powder river snail sesame sea mustard. whole milk powder. snapping turtle loach sea tangle(dried) opossum shrimp and sea lettuce(dried). And the calcium rich foods by the calcium content in one serving were in order of river snail snapping turtle opossum shrimp loach spiny lobster skate skim milk powder small alaska pollack freshwater crab condensed milk whole milk powder skate ray and milk. 3) The 3 major calcium supply food groups in Korean were vegetables fish and shellfishes and milk and dairy products. 4) The calcium supply foods according to the quantity of food supply in 1997 was in order of sea mustard, milk anchovy chinese cabbage soybean skin milk powder laver shrimp welsh onion and maize. The vegetables were the important sources of calcium in Korean. 2. The food sources of iron 1) The food sources of iron which are commonly presented in the textbooks of middle and high school were meat liver egg(egg yolk) and green vegetables etc 2) The iron rich foods on the basis of the iron content in 100g edible portion were in order of surf clam marsh clam laver(dried)( sea lettuce(dried), crayfish pelilla seed little neck clam orient hard clam, venus clam, and freshwater carab. And the iron rich foods by the iron content in one serving were in order of surf clam marsh clam crayfish little neck clam orient hard clam freshwater crab venus clam hen cockle green confertii(fresh) pen shell and spiny lobster. 3) The 3 major iron supply food groups in Korean were cereals an cereal products fishes and shellfishes and vegetables. 4) The iron supply food according to the quantity of food supply in 1997 was in order of soybean sea mustard maize rice meat edible viscera laver wheat flour, pook, red pepper, egg and bovine meat.

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Effect of Physical, Chemical Properties and of Pelleting Solid Materials on the Germination in Pelleted Carrot Seeds (펠렛 피복물질의 물리, 화학적 특성이 당근 펠렛종자의 발아력에 미치는 영향)

  • Kang, Jum-Soon;Son, Beung-Gu;Choi, Young-Whan;Lee, Yong-Jae;Park, Young-Hoon;Choi, In-Soo
    • Journal of Life Science
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    • v.17 no.12
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    • pp.1701-1708
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    • 2007
  • Seed pelleting is generally conducted in order to save the labor for sowing and thinning by enabling the precision mechanical planting. In the present study, the influence of physical and chemical properties of pelleting solid materials was investigated on carrot seed germination. Among the pelleting solid materials evaluated, dialite, kaolin, and talc showed low bulk density and high porosity. Bentonite and dialite carried high water holding capacities of 184% and 173%, respectively, while calcium carbonate, calcium oxide, and fly ash showed relatively low water holding capacity. The pH of kaolin (6.8) and dialite (7.4) were close to neutral, while limestone (12.8), calcium oxide (13.0), and bentonite (10.0) were highly basic. High electro-conductivity was shown in limestone and calcium oxide. EDS analysis revealed that the main elemental compositions of talc were Si (71.0%) and Mg (29.0%), and those of calcium carbonate were Ca (66.6%), Si (22.9%), and Mg (10.5%). High granulation capacity was observed from talc and the mixture of talc and calcium carbonate. Seeds pelleted with bentonite showed the highest hardness. The dissolving type of the pellet layer after imbibition was split type in talc, limestone, zeolite, and fly ash, melt type in calcium carbonate and calcium oxide, and swell type in bentonite and vermiculite. The shortest dissolving time of pellet layer was observed from calcium carbonate and kaolin. The germination speed $(T_{50})$ was delayed as the size of pelleted seeds increased. The optimum size of pelleting was 19 ratio in carrot.

Effect of School Lunch Menu Intervention through Calcium Enriched Menus on Nutrient Intakes of High School Girls (칼슘강화 메뉴 첨가에 의한 학교급식 식단 조정이 여고생의 영양소 섭취 개선에 미치는 효과)

  • Lee, Eon-Kyoung;Choi, Young-Sun;Bae, Bok-Seon
    • Korean Journal of Community Nutrition
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    • v.16 no.2
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    • pp.265-277
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    • 2011
  • This study was conducted to improve the nutritional status of high school girls via lunch menu intervention. Surveys were carried out twice to evaluate basal status and status after lunch menu intervention. In the first survey nutrient intakes of 24-hour and school lunch were each estimated by 24-hour recall dietary survey and self-recording, respectively. Calcium intake was the lowest among nutrients, and stir-frying was the most preferred cooking method. Five dishes of school lunch menus which were included in the first survey were replaced with recipes containing foods with higher calcium level; anchovy stir-fried with red pepper paste, anchovy stir-fried with almond, pork stir-fried with shredded kelp, crab meat soup, and tteokbokki with cheese. In the second survey calcium intake from school lunch was significantly (p < 0.001) increased from 45.5% to 50.2% of one thirds of recommended intake (RI) after calcium enriched lunch menu intervention. Intakes of vitamin A and E were also significantly increased, whereas those of energy, thiamin, and vitamin C were decreased. Index of nutritional quality values of nutrients of 24-hour intakes (except thiamin, vitamin B6, vitamin C) is increased by intervention; however, those of calcium, folic acid, iron are still very low. Even though this study shows a possibility of improving nutrient intakes of students through school lunch menu intervention, lunch intervention by itself is not enough action to improve nutritional status of micronutrient for adolescents.

Effect of Initial Volume of Hard Water and Contact Time on the Reduction of Calcium Ion Concentration using High Voltage Impulse Technique (고전압 임펄스 기술을 활용한 경도 제거에서 경수의 초기부피와 인가시간이 칼슘이온 농도에 미치는 영향)

  • Cho, Seung-Yeon;Kim, Tae-Hui;Chang, In-Soung;Hong, Woong-ki;Lee, June-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.7
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    • pp.1066-1071
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    • 2017
  • Recently high voltage impulse (HVI) technique has been extensively studied for desalting processes to control the $CaCO_3$ scale formation in industrial water practices such as power plant, boiler, and heat exchange operations. Investigation of the operational parameters for the HVI is important, however, those had not been reported yet. In this study, the effect of initial feed volume and contact time on reduction of calcium ion concentration by the HVI technique was investigated. Initial feed volumes of artificial hard water which contained 100 mg/L of $Ca^{2+}$, were set to 1, 2, and 3 L respectively. After 24hr of HVI contact with 12kV, $Ca^{2+}$ ion was reduced to 50, 29 and 19 % of their initial concentration, indicating that calcium removal increased as initial feed volume decreased. This implies the applied HVI pulse energy per unit mass of calcium is important parameter determining overall desalting efficiency. A series of extended operations of HVI up to 30 days verified the long term stability of the HVI system. The calcium ion declined to 40 mg/L after 2~3 days, and further reduction of calcium was not achieved, indicating that optimum operation time could be 2~3 days under these experimental conditions. Consequently, it was confirmed that the important operational parameter of HVI technique is initial feed volume and contact time as well as the applied voltage that was already proven in the previous study.

Synthesis of ultrafine calcium carbonate powders from high concentrated calcium hydroxide solution (고농도 수산화칼슘 수용액으로부터 초미립 경질 탄산칼슘 분말의 합성)

  • Ahn, Ji-Whan;Park, Charn-Hoon;Kim, Jeong-Heo;Lee, Jong-Kook;Kim, Hwan
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.6 no.4
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    • pp.509-520
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    • 1996
  • Ultrafine calcim carbonate powders with the size of $0.05~0.1\;{\mu}m$ and the calcite phase were synthesized by the nozzle spouting method, which could be only obtained when high calcium ion concentration within slurry was maintained at the beginning of the reaction. But, in the regions of low ${Ca(OH)}_2$ concentration (0.5~1.0 wt%) or high ${Ca(OH)}_2$ concentration (<3.0 wt%), synthesized calcium carbonate powder was shown the large particle size with agglomeration. To obtain ultrafine calcium carbonate powder in this region, the methods of slurry circuation and $CO_{2}$ gas supply were changed during reaction. Resultly, it was possible to synthesize ultrafine particles (${\approx}0.05{\mu}\textrm{m}$)in the regions of low ${Ca(OH)}_2$ concentration (${\approx}0.5wt%$) and high ${Ca(OH)}_2$ concentration (${\approx}0.5wt%$), which can not be obtained the fine calcium carbonate powder still now.

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