• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2429-2432
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• 2013

Background and Objectives: Yanting in Sichuan Province is one of the highest risk areas of esophageal cancer (EC) in the world. We here summarize the epidemiology of EC in Yanting using data from the national screening programme during 2006-2011. Methods: Random cluster sampling was used to select a proportion of natural villages from six towns in Yanting, and residents aged 40-69 years old were invited for screening. Participants were screened using endoscopy with iodine staining and then confirmed by histological examinations. Results: The overall detection rates of low-grade hyperplasia (LH), moderate hyperplasia (MH), high-grade hyperplasia (HH), carcinoma in situ (CIS), intramucosal carcinoma (IC) and invasive carcinoma (INC) were 5.33%, 1.28%, 0.68%, 0.15%, 0.06% and 0.29%, respectively. The detection rates of LH, MH, HH and INC increased with age, reaching the peak among those aged 60-65 years, and the prevalences of LH and MH were higher among men than among women. In addition, the detection rates of hyperplasia were much higher in mountainous than in hilly areas. Conclusions: Among the high risk population, there are a great number of people with early-stage EC or precancerous conditions who do not have presenting symptoms. In particular, the elderly, men, or those living in mountainous areas are the most vulnerable population. It is therefore important to reinforce health education and screening services among such high risk populations.

• Journal of Genetic Medicine
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• 제13권1호
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• pp.26-30
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• 2016

Purpose: Genetic disorders can be prevented by basic public health measures and activities that focus primarily on education and approaches in Primary Health Care. Premarital screening is one such approach that can identify asymptomatic carriers of hemoglobinopathies and provide genetic counseling to couples for a healthy reproductive life. This study aimed to estimate the prevalence of beta thalassemia and sickle cell disorders in the adult population screened as a part of the United Arab Emirates Premarital Screening Program and to measure the effectiveness of the program in decreasing high-risk marriages in Ras Al Khaimah (RAK). Materials and Methods: A retrospective, population-based study was conducted at the RAK Primary Health Care Center, where the National Premarital Screening Program is implemented. The study included data collected from the premarital screening records of all couples who had applied for a marriage license during 2008-2015. Results: Of the 17,826 individuals screened during the studied period, 4.02% (717) were diagnosed as positive for hemoglobinopathies. The prevalence of beta thalassemia and sickle cell disorders among the total study population was 2.98% and 1.05%, respectively. The hemoglobinopathy trait was more prevalent than the disease. Among these 8,913 couples who were issued certificates for compatibility based on screening tests, 28 (0.31%) couples were declared high-risk (unmatched). Seventy percent of these unmatched couples reported consanguineous marriages. Conclusion: The program was successful in achieving its objective of identifying high-risk marriages. In spite of the counseling, however, all of the high-risk couples still married each other.

• Journal of Preventive Medicine and Public Health
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• 제21권1호
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• pp.82-88
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• 1988

The main objectives of this study were to know the prevalence of cerebrovascular diseases, to find the important risk factors of cerebrovascular diseases. This study is a part of Eumseong Community Health Project supportes by GTZ(West German Goverment). 116 perceived cases of cerebrovascular diseases were first screened by health interview and examinations and 80 cases were diagnosed as a cerebrovascular group. For comparison, 80 cases were matched with their neighbor controls of the same sex and the similar age. 1. The prevalence rate for cerebrovascular diseases was 476.3 per 100,000 population which is considered to be very high compared with that of other countries. Age adjusted rate for cerebrovascular diseases was 261.6 per 100,000. 2. Among the risk factors examined for the association with cerebrovascular diseases by case-control study, and analysed by paired marginal test(McNemar's $X^2$-test) and odds ratio, only hypertension showed high significant statistical association.

• 보건행정학회지
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• 제31권2호
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• pp.158-172
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• 2021

Background: Metabolic syndrome has been known as a risk of cardiovascular disease. Meanwhile, high sensitivity C-reactive protein (hs-CRP) is used as a predictor of cardiovascular disease. In this paper, we aimed to investigate the association between hs-CRP and metabolic syndrome. Method: A total of 7,633 were chosen as the study population from the 7th Korea National Health and Nutrition Examination Survey dataset (2016-2017). Our dependent variable was whether an individual had metabolic syndrome or not, and the independent variable of interest was hs-CRP which was categorized into three groups. The chi-square tests and hierarchical logistic regression analyses reflecting survey characteristics were conducted. All analyses were stratified by gender. Results: According to the adjusted model with all covariates, compared to individuals having the low risk of hs-CRP, those having its average risk were more likely to have metabolic syndrome in men (odds ratio [OR], 1.41; 95% confidence interval [CI], 1.12-1.76) and women (OR, 1.69; 95% CI, 1.33-2.16). Individuals having the high risk was not significantly different in men; however, they were more likely to have metabolic syndrome in women (OR, 2.03; 95% CI, 1.28-3.23). Conclusion: In an upcoming aging society, it is important to reduce the risk of metabolic syndrome to improve population health. This study suggests that hs-CRP may be used as a marker of the risk of metabolic syndrome in a gender-specific way, thereby contributing to enhancing awareness of the risk of metabolic syndrome among the general public.

• 대한간호학회지
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• 제34권3호
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• pp.430-439
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• 2004

Purpose: The purpose of this study was to examine risk factors for sexual behaviors in Korean female high school students. Methods: Data was collected by a written questionnaire from June 22 to July 18, 2002 from 522 girls, who were stratified samples from a target population of 63,375 11th grade students from 200 regular high schools and 70 vocational high schools in Seoul, Korea. We conducted multiple regression analysis using the SAS pc＋ program. Results: Risk factors for intimate behaviors were association with boy friends, differential association, family attachment, and family abuse experience. These variables cause 68% of intimate behaviors. Risk factors for sexual experiences were differential association, association with boy friend, and family attachment. These variables cause 14% of sexual experiences. Conclusion: Efforts to reduce sexual behaviors in girls should include the possible role of peers and develop peer leader programs.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.723-726
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• 2013

Background: Breast cancer is worldwide the most common cancer in women and is a major public health problem. Genes with high or low penetrance are now clearly implicated in the onset of breast cancer, mostly the BRCA genes. All women in families at high risk of breast cancer do not develop tumours, even when they carry the familial mutation, suggesting the existence of genetic and environmental protective factors. Several studies have shown that consanguinity is linked to a decreased or an increased risk of breast cancer, but to the best of our knowledge, there is no study concerning the association between consanguinity and the occurrence of tumours in women with high risk of breast cancer. The objective of this study was to examine whether parental consanguinity in families with genetic predisposition to breast cancer affect the risk of siblings for having this cancer. Materials and Methods: Over a six-year period, 72 different patients with a histological diagnosis of breast or ovarian cancer from 42 families were recruited for genetic counselling to the Department of Medical Genetics, Rabat. Consanguinity rate was determined in cases and compared to the consanguinity rate in the Moroccan general population. Results: Consanguinity rates were 9.72% in patients and 15.3% in controls, but the difference was statistically not significant (p>0.001) and the mean coefficient of consanguinity was lower in breast cancer patients (0.0034) than in controls (0.0065). Conclusions: Despite the relatively small sample size of the current study, our results suggest that parental consanguinity in Moroccan women might not be associated with an altered risk of breast cancer. Large scale studies should be carried out to confirm our results and to develop public health programs.

• 한국인구학
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• 제26권2호
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• pp.91-110
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• 2003

고위험 음주는 개인 건강 뿐 아니라 사회에 막대한 부담을 초래한다. 본 연구는 보건복지부와 서울대학교외 건강위험요인 전국조사 자료에 중도 절단 이변량 프로빗 모형(bivariate probit model with censoring)을 활용하여 한국 사회에서 15세 이상 인구계층의 고위험 음주에 미치는 요인을 규명하였다. 연구결과에 따르면 우리나라에서 소주가 음주 주종 중 고위험 음주와 가장 관련성이 큰 주종임이 밝혀졌다. 그동안 소주의 문제점에 관해서는 대부분 인식하고 있었으나 전국 조사 자료 및 최신 통계분석방법을 적용한 연구가 전무하여 실증적인 뒷받침이 되지 않았던 사실이 밝혀진 셈이다. 또한 나이가 많은 계층, 배우자와 동거하지 않는 계층, 경제활동에 종사하는 계층, 스트레스에 취약한 계층, 다양한 주종을 소비하는 계층이 각각 상대적으로 그렇지 않는 계층에 비해 고위험 음주를 할 가능성이 높았다. 본 연구결과로써 한국 사회에서 음주로 인한 위해를 감소시키기 위해서는 주종별로 차별화된 정책과 함께 고위험 음주 가능성이 상대적으로 높은 인구계층을 대상으로 정부 및 민간 노력이 집중되어야 한다는 정책적 시사점을 도출할 수 있었다.

• Journal of Preventive Medicine and Public Health
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• 제53권5호
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• pp.313-322
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• 2020

Objectives: This study was conducted to determine the incidence and risk factors of myocardial infarction (MI) and stroke in farmers compared to the general population and to establish 5-year prediction models. Methods: The farmer cohort and the control cohort were generated using the customized database of the National Health Insurance Service of Korea database and the National Sample Cohort, respectively. The participants were followed from the day of the index general health examination until the events of MI, stroke, or death (up to 5 years). Results: In total, 734 744 participants from the farmer cohort and 238 311 from the control cohort aged between 40 and 70 were included. The age-adjusted incidence of MI was 0.766 and 0.585 per 1000 person-years in the farmer and control cohorts, respectively. That of stroke was 0.559 and 0.321 per 1000 person-years in both cohorts, respectively. In farmers, the risk factors for MI included male sex, age, personal history of hypertension, diabetes, current smoking, creatinine, metabolic syndrome components (blood pressure, triglycerides, and high-density lipoprotein cholesterol). Those for stroke included male sex, age, personal history of hypertension, diabetes, current smoking, high γ-glutamyl transferase, and metabolic syndrome components (blood pressure, triglycerides, and high-density lipoprotein cholesterol). The prediction model showed an area under the receiver operating characteristic curve of 0.735 and 0.760 for MI and stroke, respectively, in the farmer cohort. Conclusions: Farmers had a higher age-adjusted incidence of MI and stroke. They also showed distinct patterns in cardiovascular risk factors compared to the general population.

• 농촌계획
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• 제30권1호
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• pp.1-13
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• 2024

There is a serious risk of regional extinction due to low birth rate and aging in Korea. Accordingly, the regional extinction index is applied to diagnose the extinction status of cities, counties, and districts. However, when the regional extinction index was applied to rural villages, most villages were found to be at 'high risk of extinction'. There is no differentiation in the level of extinction of rural villages. Therefore, a village extinction index was developed to apply to rural villages. This study applies and compares the existing regional extinction index and the newly developed village extinction index to rural villages. The purpose is to propose an index that can better diagnose the extinction of rural villages. As a research method, the regional extinction index and village extinction index are applied to all villages in Haengjeong-ri villages in South Chungcheong Province. And the adequacy of the index suitable for rural villages is diagnosed. For this purpose, ➂ stage distribution for each two indices, ➂ demographic aspect diagnosis, and ➂ resident awareness survey were analyzed. When the village extinction index was used, the discrimination problems seen in the regional extinction index were overcome. As a result of the demographic analysis, the regional extinction index showed that villages with a population of 200 or more were at 'high risk of extinction', but the village extinction index was derived as 'high risk of extinction' for villages with underpopulated populations. Lastly, the results of the residents' awareness survey also showed that the village extinction index was well reflected in the actual situation of rural villages when applied. When the village extinction index was applied to rural villages rather than the regional extinction index, it was found to reflect the actual state of rural extinction better.

• Journal of Preventive Medicine and Public Health
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• 제46권4호
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• pp.155-164
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• 2013

Noncommunicable diseases (NCDs) are the most important causes of premature mortality and disability-adjusted life years in Korea. NCDs are also the main contributor to socioeconomic inequalities in mortality and life expectancy. Reduction of NCDs and NCD inequalities would result in significant improvement in healthy life expectancy and health equity in Korea. Major NCD risk factors such as dietary risks (including salt intake), alcohol consumption, cigarette smoking, and high blood pressure were found to be the leading modifiable risk factors of disability-adjusted life years in Korea, based on the 2010 Global Burden of Disease Study. Several Korean studies have shown that these risk factors play an important role in creating socioeconomic inequalities in NCD mortality and total mortality. Current international discussions on NCD policies in the United Nations and the World Health Organization would provide better opportunities for developing aggressive population-wide policy measures in Korea. Considering the paucity of population-wide policies to control major NCD risk factors in Korea, rigorous population approaches such as taxation and regulation of unhealthy commodities as well as public education and mass campaigns should be further developed in Korea.