• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.48 no.2
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• pp.119-125
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• 2020

A high Reynolds number transonic wind tunnel has been built in 2018 at Agency for Defense Development(ADD). The tunnel has a closed circuit with a 1.5m×1.5m test section and is injection driven from a 140bar air supply system. The Mach number range is 0.3-1.2 with a conventional contracting nozzle and 1.4 with a convergent-divergent contraction. The stagnation pressure range is 100-550kPa at the lowest Mach number. An AGARD-B standard model is tested in the transonic wind tunnel to obtain 6-DOF aerodynamic coefficients. The results are compared with those obtained from ADD trisonic wind tunnel and others. We verify that the transonic wind tunnel become available to develop an aircraft from the testing results.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.360-362
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• 2002

Myocardial tagging technique such as spatial modulation of magnetization (SPAMM) allows the study of myocardial motion with high accuracy. Tagging contrast of such a tagging images can affect to the accuracy of the estimation of tag intersection in order to analyze the myocardial motion. Tagging contrast can be affected by tagline spacing. The aim of this study was to investigate the relationship between tagline spacing of SPAMM image and tagging contrast-to-noise ratio (CNR) experimentally. One healthy volunteer was undergone electrocardiographically triggered MR imaging with SPAMM-based tagging pulse sequence at a 1.5T MR scanner (Gyroscan Intera, Philips Medical System, Netherland). Horizontally modulated stripe patterns were imposed with a range from 3.6mm to 9.6mm of tagline spacing. Images of the left ventricle (LV) wall were acquired at the mid-ventricle level during cardiac cycle with FEEPI (TR/TE/FA=5.8/2.2/10). Tagging CNR for each image was calculated with a software which developed in our group. During contraction, tagging CNR was more rapidly decreased in case of short tagline spacing than in case of long tagline spacing. In the same heart phase, CNR was increased corresponding with tag line spacing. Especially, at the fully contracted heart phase, CNR was more rapidly increased than the other heart phases as a function of tagline spacing.

• The Journal of Korean Physical Therapy
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• v.25 no.2
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• pp.49-55
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• 2013

Purpose: This study was conducted in order to analyze the effect of proprioceptive neuromuscular facilitation lower extremity pattern on muscular strength and flexibility in an aquatic environment. Methods: Ten members of the experimental group and 10 members of the control group were randomly selected from 20 college students who are in their 20s. Bilateral symmetry pattern among proprioceptive neuromuscular facilitation lower extremity patterns was applied in an aquatic environment in the experimental group three times per week for a period of six weeks, and a set consisted of 10 times, which was repeated 10 times. On the other hand, subjects in the control group did not receive any treatment while maintaining daily life. Muscular strength was measured using a dynamometer and electromyogram system for maximum voluntary isometric contraction of hip flexor, hip extensor, knee flexor, and knee extensor. Cervical flexibility was measured using cervical range of motion instrument for cervical flexion, rotation, and lateral flexion. Lumbar flexibility was measured using back range of motion instrument II for lumbar flexion. Results: For the experimental group, significance was observed for hip flexor, extensor, knee flexor, extensor, cervical flexion, rotation, lateral flexion, and lumbar flexion. For the control group, no significance was observed for any other variables except for cervical flexion. As a result of observation of difference between the two groups, relatively high significance was observed in the experimental group, compared with the control group. Conclusion: In conclusion, proprioceptive neuromuscular facilitation lower extremity pattern had a positive effect on muscular strength and flexibility in an aquatic environment.

• YAKHAK HOEJI
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• v.59 no.4
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• pp.158-163
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• 2015

Cardiac myocytes are subjected to fluid shear stress during each contraction and relaxation. Under pathological conditions, such as valve disease, heart failure or hypertension, shear stress in cardiac chamber increases due to high blood volume and pressure. The shear stress induces proarrhythmic longitudinal global $Ca^{2+}$ waves in atrial myocytes. In the present study, we further explored underlying cellular mechanism for the shear stress-induced longitudinal global $Ca^{2+}$ wave in isolated rat atrial myocytes. A shear stress of ${\sim}16dyn/cm^2$ was applied onto entire single myocyte using pressurized fluid puffing. Confocal $Ca^{2+}$ imaging was performed to measure local and global $Ca^{2+}$ signals. Shear stress elicited longitudinally propagating global $Ca^{2+}$ wave (${\sim}80{\mu}m/s$). The occurrence of shear stress-induced atrial $Ca^{2+}$ wave was eliminated by the inhibition of ryanodine receptors (RyRs) or inositol 1,4,5-trisphosphate receptors ($IP_3Rs$). In addition, pretreatment of phospholipase C (PLC) inhibitor U73122, but not its inactive analogue U73343, abolished the generation of longitudinal $Ca^{2+}$ wave under shear stress. Our data suggest that shear-induced longitudinal $Ca^{2+}$ wave may be induced by $Ca^{2+}$-induced $Ca^{2+}$ release through the RyRs which is triggered by $PLC-IP_3R$ signaling in atrial myocytes.

• Applied Chemistry for Engineering
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• v.5 no.3
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• pp.443-450
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• 1994

Polyelectrolytes of various ionization degrees, which are prepared by neutralization of poly(acrylic acid)(PAA), were crosslinked by ethylane glycol diglycidyl ether(EGDE) in aqueous solution. $C_{gel}$, the minimum polymer concentration at which gelation occurs, was higher than expected. $C_{gel}$ was comparable with that of neutral polymer. This is considered to be due to the size contraction of polyelectrolyte, which comes from ionic strength increase as polymer concentration is increased. $C_{gel}$ is low when molecular weight of the sample becomes high. It reveals that polyelectrolyte is crosslinked in coil form not in extended rod form. This behavior is similar to the crosslinking of neutral polymers. Polyelectrolytes of partially ionized sample generally follow the behavior of fully ionized polyelectrolyte. Polyelectrolyte with added salt was also studied. Considering the pH dependence of EDGE reactivity it was difficult to compare the system which differs in pH significantly.

• Journal of the Korean Society of Radiology
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• v.2 no.1
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• pp.23-29
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• 2008

The present study proposed a method that dissolves ultrasonographic images into multiple resolutions using wavelet conversion and a boundary detection filter and improves the quality of ultrasonographic images through boundary detection filtering. In order to reduce noises and strengthen edges, the proposed method adjusted selectivity coefficient by area step by step from a low resolution image obtained from wavelet converted images to a high resolution image and performed edge filtering in consideration of direction. Through this method, we generated a selective low pass filtering effect in areas except edges by decreasing the wavelet coefficient for pixels in spot areas, improved continuity by smoothing edges in the tangential direction, and enhanced contrast by thinning in the normal direction. Through an experiment, we compared the filtering method using a non linear anisotropic expansion model and the filtering method using wavelet contraction structure in single resolution.

• Journal of Electrochemical Science and Technology
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• v.3 no.1
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• pp.29-34
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• 2012

The structural changes of $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ cathode material for lithium ion battery during the first charge was investigated in comparison with $Li_{1-x}Ni_{0.8}Co_{0.15}Al_{0.05}O_2$ using a synchrotron based in situ X-ray diffraction technique. The structural changes of these two cathode materials show similar trend during first charge: an expansion along the c-axis of the unit cell with contractions along the a- and b-axis during the early stage of charge and a major contraction along the c-axis with slight expansions along the a- and b-axis near the end of charge at high voltage limit. In $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ cathode, however, the initial unit cell volume of H2 phase is bigger than that of H1 phase since the c-axis undergo large expansion while a- and b- axis shrink slightly. The change in the unit cell volume for $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ during charge is smaller than that of $Li_{1-x}Ni_{0.8}Co_{0.15}Al_{0.05}O_2$. This smaller change in unit cell volume may give the $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ cathode material a better structural reversibility for a long cycling life.

• The Journal of Korean Physical Therapy
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• v.21 no.4
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• pp.57-63
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• 2009

Purpose: To better understand falls in elderly women, we measured differences in muscle activities of 4 lower extremity muscles (tibialis anterior, soleus, rectus femoris, biceps femoris) based on angle plantar-flexion in elderly women. Methods: Subjects were 15 healthy elderly women. No subjects had musculoskeletal or nervous disorders. EMGs were used to check muscle activity of lower extremity muscles. For statistic analysis, data were expressed as a percentage of maximal voluntary isometric contraction (%MVIC). We measured %MVIC for 5 sec under 4 conditions and did not use data for the first and last second. Muscle activities of the muscles of the lower extremities were measured based on the degree of plantar-flexion of the ankle joint. The 4 conditions corresponded to different degrees of: 0, 10, 20 and 30 degrees. This was done using a 50 cm board for measuring the degrees. Results: The tibialis anterior, soleus, and bicpes femoris showed increasing muscle activity associated with increasing degree of plantar-flexion of the ankle joint. All muscles showed a significant increase in muscle activities in association with increasing degrees. Rectus femoris showed a significant increase in muscle activity for 0 degrees and for the other degrees, but there were no further changes when plantar flexion of the ankle joint was over 10 degrees. Conclusion: Activities of the muscles of the lower extremities except rectus femoris were higher with increasing degree of plantar flexion. High muscle activity may result in muscle fatigue. Thus, increasing degree of plantar flexion may be risk factors of falls in elderly women.

• Korean Journal of Applied Biomechanics
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• v.22 no.1
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• pp.113-121
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• 2012

The purpose of this study was to evaluate the effects of forefoot rocker shoes equipped with a metatarsal bar on lower extremity muscle activity and plantar pressure distribution. Ten healthy women in the age of twenties were participated in this study as the subjects. All subjects walked on a treadmill(Gait Trainer, BIODEX, USA) wearing normal shoes and metatarsal bar shoes, during which the plantar pressure distribution and muscle activity were measured. Using Pedar-X system(Novel Gmbh, Germany), the plantar pressure was measured for six regions of the foot: forefoot, midfoot, rearfoot, 1st metatarsal, 2-3th metatarsal, and 4-5th metatarsal, and for each sub-region, 4 features such as maximum force, contact area, peak pressure, and mean pressure were analyzed based on the plantar pressure. EMG(Electromyography) activity was measured by attaching surface electrodes to the rectus femoris, biceps femoris, tibialis anterior, and gastrocnemius medial head, and magnitude of muscle contraction was analyzed in IEMG(Integrated EMG) value. The results show that the maximum force, contact area, peak pressure, and mean pressure in the midfoot all increased while maximum force, peak pressure, contact area, mean pressure in the 1st metatarsal and 2-3th metatarsal all decreased when wearing functional shoes. Also, muscle activities in the four muscles were all decreased when wearing the functional shoes. This paper suggests that forfoot rocker shoes equipped with a metatarsal bar can help disperse the high pressure and absorb the shock to the foot as well as give positive influence on gait pattern and postural stability by reducing muscle fatigue during walking.

• Biomolecules & Therapeutics
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• v.28 no.4
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• pp.328-336
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• 2020

Diabetes mellitus affects the colonic motility developing gastrointestinal symptoms, such as constipation. The aim of the study was to examine the role of intracellular signaling pathways contributing to colonic dysmotility in diabetes mellitus. To generate diabetes mellitus, the rats were injected by a single high dose of streptozotocin (65 mg/kg) intraperitoneally. The proximal colons from both normal and diabetic rats were contracted by applying an electrical field stimulation with pulse voltage of 40 V in amplitude and pulse duration of 1 ms at frequencies of 1, 2, 4, and 6 Hz. The muscle strips from both normal rats and rats with diabetes mellitus were pretreated with different antagonists and inhibitors. Rats with diabetes mellitus had lower motility than the control group. There were significant differences in the percentage of inhibition of contraction between normal rats and rats with diabetes mellitus after the incubation of tetrodotoxin (neuronal blocker), atropine (muscarinic receptor antagonist), prazosin (α₁ adrenergic receptor antagonist), DPCPX (adenosine A1 receptor antagonist), verapamil (L-type Ca²⁺ channel blocker), U73122 (PLC inhibitor), ML-9 (MLCK inhibitor), udenafil (PDE₅ inhibitor), and methylene blue (guanylate cyclase inhibitor). The protein expression of p-MLC and PDE₅ were decreased in the diabetic group compared to the normal group. These results showed that the reduced colonic contractility resulted from the impaired neuronal conduction and decreased muscarinic receptor sensitivity, which resulted in decreased phosphorylation of MLC via MLCK, and cGMP activity through PDE₅.