• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5407-5413
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• 2015

Background: Published data regarding associations between the P275A polymorphism in the macrophage scavenger receptor 1 (MSR1) gene and prostate cancer (PCa) risk are inconclusive. The aim of this study was to comprehensively evaluate the genetic risk of P275A polymorphism in MSR1 gene for PCa. Materials and Methods: A systematic literature search was carried out in Pubmed, Medline (Ovid), Embase, CBM, CNKI, Weipu, and Wanfang databases, covering all available publications (last search was performed on Apr 27, 2015). Statistical analysis was performed using Revman 5.2 and STATA 10.1 software. Results: A total of 5,017 cases and 4,869 controls in 12 case-control studies were included in this meta-analysis. When all groups were pooled, there was no evidence that the P275A polymorphism had a significant association with PCa under dominant (OR=0.93, 95%CI=0.81-1.06, and p=0.28), co-dominant (homogeneous OR=0.97, 95%CI=0.56-1.68, and p=0.92; heterogeneous OR=0.93, 95%CI=0.74-1.15, and p=0.49), recessive (OR=1.10, 95%CI=0.65-1.87, and p=0.73), over-dominant (OR=0.93, 95%CI=0.75-1.15, and p=0.50), and allelic (OR=0.95, 95%CI=0.77-1.16, and p=0.61) genetic models. For stratified analyses by ethnicity and study design, no significant associations were found in the white race, the yellow race, the black race and mixed ethnicity, and the population-based case-control (PCC) and hospital-based case-control (HCC) studies under all genetic models. Conclusions: Based on our meta-analysis, the P275A polymorphism in the MSR1 gene is unlikely to be a risk factor for PCa.

• Journal of Korean Society for Geospatial Information Science
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• v.17 no.4
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• pp.23-29
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• 2009

Recent growth of the geospatial information on the Web has made it possible to easily access a wide variety of geospatial information. An integration of different geospatial objects consists of the following three steps; extracting geospatial objects from the maps, converting the coordinate system and discovering pairs of objects that represent the same real-world entity in the two maps. This paper deals mainly with the third step to correspond conjugate objects and four matching types and criteria is presented. The techniques designed and developed can be utilized to efficiently integrate distributed heterogeneous spatial databases such as the digital maps and POIs from other data sources. To achieve the goal, we presented four types and criteria for the matching schema. The main contributions of this paper are as follows. A complete process of integrating data from maps on the Web is presented. Then, we show how attributes of the objects can be used in the integration process.

• Korean Journal of Health Education and Promotion
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• v.21 no.4
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• pp.15-33
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• 2004

With growing significance of psychological well-being in the worksite, the purpose of this analysis was to overview the empirical studies on worksite stress management and to identity the overall effect of worksite health promotion programs on stress management through meta-analysis. Literature retrieval was conducted on-line first in MEDLINE, EBSCOhost Academic Search Premier, and PSYCHINFO databases in public health, psychology, sociology, and human resource management areas. All studies written in English and published in the peer-reviewed journals during 1990 and 2002 were recruited. Key words used in literature retrieval were 'worksite,' 'intervention,' 'program,' 'work stress,' 'strain,' 'burnout,' 'management,' 'prevention,' 'education,' and 'health promotion.' A total of 18 worksite intervention studies with 48 effect sizes were analyzed and the results were as follows. Approximately 60％ of the studies had quasi-experimental design and were conducted in manufacturing company and public sector. General psychological strains and burnout were frequently used measures of psychological stress. The lecturing and discussion typed intervention and the participatory problem-solving typed intervention were employed more than others in the studies. The average effect (r: pearson's simple correlation coefficient) weighted by sampling error was -0.14 (-0.32 to 0.05). In the conventional category of effects this is a small effect ranging from -0.59 to 0.05. Binomial effect size showed that success rates increased from 43％ without intervention to 57％ after an intervention. Sampling error explained 47.14％ of the observed variance and its effectiveness on stress management were heterogeneous. In regression analysis with suspected moderating factors affecting the worksite interventions, research design was the only significant moderating factor. The studies with quasi-experimental design had greater effects than the studies with experimental design.

• Journal of the Korea Society of Computer and Information
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• v.10 no.1 s.33
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• pp.59-66
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• 2005

The organization of the web is progressively more being used to improve search and analysis of information on the web as a large collection of heterogeneous documents. Most people begin at a Web search engine to find information. but the user's pertinent search results are often greatly diluted by irrelevant data or sometimes appear on target but still mislead the user in an unwanted direction. One of the intentional, sometimes vicious manipulations of Web databases is a intentionally biased web page like Google bombing that is based on the PageRank algorithm. one of many Web structuring techniques. In this thesis, we regard the World Wide Web as a directed labeled graph that Web pages represent nodes and link edges. In the Present work, we define the label of an edge as having a link context and a similarity measure between link context and target page. With this similarity, we can modify the transition matrix of the PageRank algorithm. By suggesting a motivating example, it is explained how our proposed algorithm can filter the Web intentionally biased web Pages effective about $60\%% rather than the conventional PageRank.

• The korean journal of orthodontics
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• v.46 no.5
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• pp.331-342
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• 2016

Objective: To evaluate the accuracy and reliability of the diagnostic tools available for assessing maxillary transverse deficiencies. Methods: An electronic search of three databases was performed from their date of establishment to April 2015, with manual searching of reference lists of relevant articles. Articles were considered for inclusion if they reported the accuracy or reliability of a diagnostic method or evaluation technique for maxillary transverse dimensions in mixed or permanent dentitions. Risk of bias was assessed in the included articles, using the Quality Assessment of Diagnostic Accuracy Studies tool-2. Results: Nine articles were selected. The studies were heterogeneous, with moderate to low methodological quality, and all had a high risk of bias. Four suggested that the use of arch width prediction indices with dental cast measurements is unreliable for use in diagnosis. Frontal cephalograms derived from cone-beam computed tomography (CBCT) images were reportedly more reliable for assessing intermaxillary transverse discrepancies than posteroanterior cephalograms. Two studies proposed new three-dimensional transverse analyses with CBCT images that were reportedly reliable, but have not been validated for clinical sensitivity or specificity. No studies reported sensitivity, specificity, positive or negative predictive values or likelihood ratios, or ROC curves of the methods for the diagnosis of transverse deficiencies. Conclusions: Current evidence does not enable solid conclusions to be drawn, owing to a lack of reliable high quality diagnostic studies evaluating maxillary transverse deficiencies. CBCT images are reportedly more reliable for diagnosis, but further validation is required to confirm CBCT's accuracy and diagnostic superiority.

• The KIPS Transactions:PartD
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• v.15D no.4
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• pp.549-556
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• 2008

Web-based Enterprise Intranet System is developed Object-oriented programming language and data management is constructed using RDBMS. Between Object-oriented programming language and RDBMS bring about "Object-Relational Impedance Mismatch" due to heterogeneous paradigm. To solve this kinds of problems commonly use the ORM Framework that it is converting data between incompatible type systems in databases and object-oriented programming languages, uses complex mapping metadata. It causes difficult to develop and maintain because of inflexible in changes. This paper proposed persistence framework that solve the existing complexity of ORM framework and has more flexible in evolution of database table. This persistence framework is unnecessary meta information that connecting with entity of database table and the objects, it offers users convenience of maintenance and it allows far more flexible and affordable systems to be built because of automatically code generation. The result of testing based on the proposed persistence framework with Hibernate, iBATIS, It is similar response time with iBATIS and it has more about three times faster than Hibernate. But iBATIS has problems of mass data processing.

• Restorative Dentistry and Endodontics
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• v.45 no.2
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• pp.25.1-25.12
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• 2020

Objectives: This systematic review evaluated the influence of autoclave sterilization procedures on the cyclic fatigue resistance of heat-treated nickel-titanium (NiTi) instruments. Materials and Methods: A systematic search without restrictions was conducted in the following electronic databases: PubMed, Scopus, Web of Science, ScienceDirect, Cochrane, and Open Grey. The hand search was also performed in the main endodontic journals. The eligible studies were submitted to the methodological assessment and data extraction. Results: From 203 abstracts, a total of 10 articles matched the eligible criteria. After reading the full articles, 2 were excluded because of the absence of the heat-treated instruments in the experimental design and 3 due to the lack of a control group using heat-treated instruments without autoclave sterilization. From the 5 included studies, 1 presented a low risk of bias, 3 presented moderate and 1 high risk. It was observed heterogeneous findings in the included studies, with autoclave sterilization cycles increasing, decreasing or not affecting the cyclic fatigue life of heat-treated NiTi instruments. However, the retrieved studies evaluating the cyclic fatigue resistance of endodontic instruments presented different protocols and assessing outcomes, this variability makes the findings less comparable within and also between groups and preclude the establishment of an unbiased scientific evidence base. Conclusions: Considering the little scientific evidence and considerable risk of bias, it is still possible to conclude that autoclave sterilization procedures appear to influence the cyclic fatigue resistance of heat-treated NiTi instruments.

• Journal of KIISE:Databases
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• v.37 no.6
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• pp.324-332
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• 2010

The majority of event detection in real-time embedded sensor network systems is based on data fusion that uses noisy sensor data collected from complicated real-world environments. Current research has produced several excellent low-level mechanisms to collect sensor data and perform aggregation. However, solutions that enable these systems to provide real-time data processing using readings from heterogeneous sensors and subsequently detect complex events of interest in real-time fashion need further research. We are developing real-time event detection approaches which allow light-weight data fusion and do not require significant computing resources. Underlying the event detection framework is a collection of real-time monitoring and fusion mechanisms that are invoked upon the arrival of sensor data. The combination of these mechanisms and the framework has the potential to significantly improve the timeliness and reduce the resource requirements of embedded sensor networks. In addition to that, we discuss about a privacy that is foundation technique for trusted embedded sensor network system and explain anonymization technique to ensure privacy.

• The KIPS Transactions:PartD
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• v.11D no.4
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• pp.755-764
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• 2004

Recently, the rapid development of biotechnology brings the explosion of biological data and biological data host. Moreover, these data are highly distributed and heterogeneous, reflecting the distribution and heterogeneity of the Molecular Biology research community. As a consequence, the integration and interoperability of molecular biology databases are issue of considerable importance. But, up to now, most of the integrated systems such as link based system, data warehouse based system have many problems which are keeping the data up to date when the schema and data of the data source are changed. For this reason, the integrated system using web service technology that allow biological data to be fully exploited have been proposed. In this paper, we built the integrated system if the bio sequence information bated on the web service technology. The developed system allows users to get data with many format such as BSML, GenBank, Fasta to traverse disparate data resources. Also, it has better retrieval performance because the retrieval modules of the external database proceed in parallel.

• Journal of Periodontal and Implant Science
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• v.51 no.6
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• pp.386-397
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• 2021

Purpose: MicroRNAs (miRNAs) are epigenetic post-transcriptional regulators that modulate gene expression and have been identified as biomarkers for several diseases, including cancer. This study aimed to systematically review the relationship between miRNAs and periodontal disease in humans, and to evaluate the potential of miRNAs as diagnostic and prognostic biomarkers of disease. Methods: The review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines (reference number CRD42020180683). The MEDLINE, Scopus, Cochrane Library, Embase, Web of Science, and SciELO databases were searched for clinical studies conducted in humans investigating periodontal diseases and miRNAs. Expression levels of miRNAs across the different groups were analysed using the collected data. Results: A total of 1,299 references were identified in the initial literature search, and 23 articles were finally included in the review. The study designs were heterogeneous, which prevented a meta-analysis of the data. Most of the studies compared miRNA expression levels between patients with periodontitis and healthy controls. The most widely researched miRNA in periodontal diseases was miR-146a. Most studies reported higher expression levels of miR-146a in patients with periodontitis than in healthy controls. In addition, many studies also focused on identifying target genes of the differentially expressed miRNAs that were significantly related to periodontal inflammation. Conclusions: The results of the studies that we analysed are promising, but diagnostic tests are needed to confirm the use of miRNAs as biomarkers to monitor and aid in the early diagnosis of periodontitis in clinical practice.