• 대한한방내과학회지
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• 제40권5호
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• pp.822-831
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• 2019

Objective: This study reports the effect of Hyungbangjihwang-tang-gami as a treatment for Soyang-in patients with chronic diarrhea. Methods: We treated three male patients with chronic diarrhea who did not improve after taking herbal medicine, as determined by zang-fu (organ) pattern diagnosis. After changing our approach to a Sasang constitution, we prescribed Hyungbangjihwang-tang-gami and assessed the effect by the frequency or form of defecation. Results: The patients' complaints worsened when they were administered a herbal medicine unsuited to their Soyang constitutions, which caused an exuberance of Yang. Changing the herbal medicine to Hyungbangjihwang-tang-gami improved their symptoms. Conclusions: This study suggested that Soyang-in patients may have side effects when administered unsuitable herbs, even if they were diagnosed using zang-fu (organ) pattern diagnosis. When we treat patients, we have to consider their Sasang constitution, as well as the zang-fu (organ) pattern diagnosis.

• 대한한방내과학회지
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• 제38권1호
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• pp.81-91
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• 2017

Objectives: This study aimed to explore and describe how two patients diagnosed with type II diabetes mellitus were successfully cured solely through the use of herbal medicine. Methods: The patients were administered the herbal medicine to reduce symptoms of stress-induced fever with dryness. The prescribed herbal medicines included Yangkyuksanwha-tang, Hyungbangsabaek-san, Hyungbangjihwang-tang, and Hyungbangdojeock-san. Results: The therapeutic outcomes showed that all numerical levels of symptoms such as thirst, polyuria, weight loss, blood sugar, and glycated hemoglobin (HbA1c) recovered to within normal levels. Conclusions: The results of this study suggest that our medical treatment of type II diabetes mellitus diagnosed as Sogal was a valid treatment. We hope that our team's new evidence and findings will shed positive light on the treatment of type II diabetes mellitus using herbal medicine.

• 사상체질의학회지
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• 제35권3호
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• pp.1-11
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• 2023

Objective This case report is to show the effectiveness of Sasang Constitutional Medicine treatment on the patient with delayed encephalopathy after acute carbon monoxide intoxication. Methods A 40-year-old female patient diagnosed with delayed encephalopathy after carbon monoxide poisoning 2 weeks ago before visiting our hospital. The patient suffered gait disturbance and cognitive disorder. She was identified as Soyangin and treated with Sasang constitutional Herbal Medicine(Yangkyuksanwha-tang and Hyungbangjihwang-tang). Improvement of symptoms was evaluated through Korean Version of Mini Mental Status Examination score(MMSE-K), Modified Barthel Index(MBI), Manual Muscle Testing(MMT), Range of Motion(ROM) and Hand Function Test. Results After 7 weeks of treatment, total score of MMSE-K increased from 0 to 26, the patient could walk by herself and had no trouble carrying out her daily life. Conclusions This case showed the effectiveness of Sasang constitutional medicine treatment for delayed encephalopathy after acute carbon monoxide intoxication.

• 사상체질의학회지
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• 제18권3호
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• pp.210-215
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• 2006

1. Objectives The purpose of this study is to give an account of the effects of Korean herbal medicine therapy which is based on Sasang constitutional medicine for two patients who were suffering from Yin Exhausted Syndrome. 2. Mothods Patients were diagnosed as having Soyangin Yin Exhausted Syndromes by Physical characteristics, posture, and symptoms and were evaluated with an interview and laboratory test after Sasang constitutional medication. 3. Result After the Sasang constitutional medications of Hyungbangsabek-san(荊防瀉白散), Hyungbangjihwang-tang(荊防地黃湯), Juhryungchajunja-tang(猪笭車前子湯), Shihochungjang-tang(柴胡淸腸湯) were used diarrhea and other symptoms were improved. 4. Conclusions These case studies show an efficient result of using Sasang traditional medicine in the treatment of Yin Exhausted Syndrome.

• 한국미생물·생명공학회지
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• 제36권1호
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• pp.82-85
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• 2008

형방지황탕은 동양 고유의 약처방으로 사람의 기력 회복에 도움을 주는 것으로 알려져 있다. 본 연구에서는 $SiO_2$ 컬럼 크로마토그래피와 HPLC를 이용하여 형방지황탕 유래의 항균 물질 (HTI)을 분리하여 그의 항균 활성을 측정하였다. 인체 감염성 그램-양성균, 그램-음성균 및 환자에게서 분리된 메티실린-내성 황색 포도상구균을 대상으로하여 CLSI방법을 이용하여 HTI 항균 활성을 측정하였다. 그 결과, HTI은 실험한 모든 세균에 대하여 넓은 범위의 항균 활성을 나타냄을 확인할 수 있었다. 이 결과를 바탕으로 하여 HTI이 항균제로서의 발전 가능성을 가진 신물질임을 확인하였으며, HTI의 화학 구조 결정을 통하여 구조와 활성간의 연구를 시행할 것이다.

• 한국미생물·생명공학회지
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• 제37권3호
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• pp.273-279
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• 2009

형방지황탕은 한의학에서 중요한 약처방으로 인간의 기력 회복에 약효가 탁월한 것으로 알려져 있다. 본 연구에서는 형방지황탕으로부터 항생 물질(HTI)을 분리하여 항진균활성 및 그 작용기작을 검토하였다. 그 결과 각종 병원성 진균에 대해 항진균 활성을 나타내었으며, 인간 적혈구에 대해서는 세포독성이 나타나지 않은 것으로 확인되었다. 또한 캔디다 알비칸스를 대상으로 스트레스 방어기작과 세포 이형성 유도에 HTI이 미치는 영향을 검토한 결과, 트리 할로즈의 증가와 이형성 유도에 영향을 미치는 것으로 나타나 이러한 현상이 항진균활성에 상관관계가 있음을 확인하였으며, 또한 진균의 세포주기에 미치는 영향도 항진균 활성의 요인이 됨을 밝혔다.

• 대한한방내과학회지
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• 제40권2호
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• pp.246-253
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• 2019

Objective: In this care report, we address a case of a Parkinson's disease patient with nausea and vomiting. Methods: A patient was treated with Korean medicine therapies including herbal medication (Hyungbangjihwang-tang, Boikyangwie-tang), acupuncture, and electroacupuncture during 35 days of hospitalization. We evaluated the improvements of symptoms by checking the number of vomiting episodes and the presence of nausea. Results: During 35 days of Korean medicine treatment, there was improvement in patient's symptoms. The frequency of vomiting had decreased, and the nausea had decreased and not appeared for the last 7 days. Conclusions: This study suggested that Korean medicine therapies might be effective in relieving gastrointestinal symptoms of Parkinson's disease.