• Herbal Formula Science
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• v.10 no.1
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• pp.33-39
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• 2002

There are total 33 prescriptions containing Polygala tenuifolia as a principal medicine in Donguibogam. This report describes the studies on therapeutic range, symptom, pathology and composition of 33 Polygala tenuifolia-main blended Prescriptions from Donguibogam. The percentage of Polygala tenuifolia-main blended prescriptions for the therapeutic range are as follows: psychopathy is the most frequent(54.4%) and eczema, purulent inflammation is second(21%) and feebleness is third(15%). The main pathologies of Polygala tenuifolia-main blended prescriptions are associated with heart, kidney and stomach. The main combinations of Polygala tenuifolia-main blended prescriptions in psychopathy are Jeongji-hwan and Chongmyung-tang.

• Biomedical Science Letters
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• v.19 no.3
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• pp.206-212
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• 2013

The herbal composition Gyeongshingangjeehwan 18 (GGEx18), which is composed of three herbs, Laminaria japonica Aresch (Laminariaceae), Rheum palmatum L. (Polygonaceae), and Ephedra sinica Stapf (Ephedraceae), has been used as an anti-obesity drug in Korean local clinics. Thus, we investigated whether GGEx18 regulates obesity by suppressing appetite in high fat diet-induced obese C57BL/6J mice. Administration of GGEx18 to obese mice for 9 weeks significantly decreased body weight gain, epididymal adipose tissue weight, and food efficiency ratio. GGEx18 also caused a significant decrease in the circulating levels of leptin, which were increased by about 450% in obese control mice compared with normal lean mice. Concomitantly, GGEx18 decreased mRNA levels of a potent appetite-stimulating hormone neuropeptide Y, but increased an appetite-suppressing hormone pro-opiomelanocortin mRNA levels. These results suggest that GGEx18 may prevent obesity through regulating appetite in nutritionally obese mice.

• Herbal Formula Science
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• v.11 no.1
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• pp.171-195
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• 2003

Objectives: This experimental study has been done to compare the Os Draconis composition before and after using processing method. Os Draconis has a quality for calming the liver meridian function and relaxation the mind. Methods: I studied the Os Draconis and processed Os Draconis by vinegar to compare the compositions and its' character. Results: Os Draconis is not a dinosaur's bone fossil but a mammal's bone fossil which has a Calcite mineral, an Apatite mineral, $SiO_2\;Al_2$ O, etc. Os Draconis contains a main ingredients CaO>50.00%. Processed Os Draconis which is heated and soaked in vinegar changes to weak condition Conclusion: Os Draconis is supposed to be a mammal's bone fossil. Some Os Draconis has a radioactive substance like a U, Th so we pay heed to deal with it in a medical clinic.

• Herbal Formula Science
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• v.11 no.1
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• pp.151-159
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• 2003

Effects of siho(Bupleuri Radix) extracts on lipid composition and antioxidant system were investigated in rat fed high fat diet. body weight gain, concentration of plasma triglyceride, total cholesterol, LDL-cholesterol showed a tendency to decrease in siho(Bupleuri Radix) extracts groups. However, the concentration of HDL-cholesterol showed no significantly different among treatments. Plasma and liver TBARS concentration showed a low values in siho(Bupleuri Radix) extracts groups. Activities of SOD, GSH-Px and CAT showed a tendency to increase in siho(Bupleuri Radix) extracts groups.

• Herbal Formula Science
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• v.20 no.2
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• pp.153-164
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• 2012

Objectives : This study was intended to establish for medical treatment range of Ojeoksan and to help extending application of medical insurance through prescriptive research. Methods : We analyzed "Dongeuibogam", "Taepyeonghaeminhwajegukbang" and other books Result : 1. composition of Ojeoksan in "Dongeuibogam" is same as in "Gogeumeuigam" 2. Ojeoksan is composed of five kinds of basic prescripitions; Er Chen Tang, Ping Wei San, Ma Huang Tang, Si Wu Tang etc. and it used for five pathological factors; cold, energy, eating, phlegm, blood. 3. Property of Ojeoksan is warm so it can be used for any cold diseases. 4. Ojeoksan is used for 16 kinds of diseases including chest pain, abdominal pain etc. Conclusion : Ojeoksan can be used for cardiovascular disorders and Ojeoksan is possible to apply or to extend medical insurance coverage.

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.519-520
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• 2010

• Korean Journal of Medicinal Crop Science
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• v.22 no.5
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• pp.363-368
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• 2014

This study was conducted to find out the optimum composition of nursery soil for raising seedling of ginseng (Panax ginseng C. A. Meyer). Total 9 kinds of raw materials were used such as peat-moss, perlite, leaf mould, rice bran, gull's guano, castor-oil plant bark, palm bark, cow manure and chicken manure for optimum composition of nursery soil in ginseng. Occurrence of damping-off in ginseng was lowered about 50% in nursery soil type 1, 2 and 4 than in other types nursery soil in June, and occurrence rate of rusty root also lowest in nursery soil type 1. As the salinity of nursery soil increased, so did the occurrence of physiological disorder in ginseng seedling. The cause of salinity increasing in nursery soil has closely relation to $NO_3-N$, $P_2O_5$ and $Na^+$ content. Plant height, root length, diameter and weight were longer and heavier in nursery soil type 1 (mixing ratio of peat-moss, perlite and leaf mould was 50 : 20 : 30 based in volume) than in other types of nursery soil. So nursery soil type 1 was selected for raising seedling of ginseng. pH and electric conductivity (EC) of selected nursery soil type 1 was 5.55 and 0.13 dS/m. Contents of $NO_3-N$ and $P_2O_5$ were 21.0 and 40.0 mg/L, and $K^+$ 0.36, $Ca^{2+}$ 3.38, $Mg^{2+}$ 2.01 and $Na^+$ $0.09cmol^+/L$, respectively.

• 한국약용작물학회:학술대회논문집
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• 2008.11a
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• pp.161-162
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• 2008

• Herbal Formula Science
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• v.25 no.2
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• pp.209-222
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• 2017

Objectives : The purpose of this study was to investigate the interpretation of the Soyo-san(SYS) prescription in order to obtain the evidence for clinical applications. Methods and Result : We interpreted on the SYS-related contents based on 25 classic books, analyzed it according to followed categories ; meaning of name, alteration of herbal composition according to age, usage, origin, physiological and pathological situation of SYS, description of each herbal drug Conclusion : 1. So(逍) mean diminish(消), 遙 mean roll(搖). It reflected feature of SYS, that alleviate depression without impairing vital energy(正氣). 2. SYS was first mentioned in the prescription of peaceful benevolent dispensary(太平惠民和劑局方), its essential application was harminizing liver depression and spleen deficiency(肝鬱脾虛) 3. SYS originated from Sayuk-san. Sayuk-san was appropriate for soothe the liver and regulate the spleen(疏肝理脾), while SYS was suitable for depressed liver and blood deficiency(肝鬱血虛) 4. Most medical literature insisted that application situation of SYS is blood deficiency(血虛), depressed liver(肝鬱), spleen deficiency(脾虛). And there is strong correlation between three factors. 5. Bupleurum falcatum L.(柴胡), Mentha arvensis L.(薄荷) alleviates liver depression as "pungent dissipate-qi uprais (辛散氣升)" nature. Angelica gigas Nakai(當歸), Paeonia lactiflora Pall.(白芍藥) emoliates the liver by nourishing the blood. Atractylodes japonica Koidz. ex Kitam.(白朮), Poria cocos(茯苓), Glycyrrhiza uralensis Fisch.(甘草), Zingiber officinale Roscoe(生薑) cultivate the basis as tonifying earth(補土).

• The Journal of Pediatrics of Korean Medicine
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• v.34 no.3
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• pp.18-36
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• 2020

Objectives The purpose of this study is to analyze Chinese randomized controlled trials (RCTs), and to evaluate the effectiveness and safety of the oral herbal medicine treatment for pediatric chickenpox. Methods We searched RCTs after 2000s from the China National Knowledge Infrastructure (CNKI). Afterwards, the year of publication, demographic information, duration of chickenpox, intervention, treatment duration, outcome measure, results and adverse events were investigated and analyzed for this study. Results 21 RCTs out of 219 studies were collected and analyzed. Although each composition of the herbal medicine was different, they have common ingredients such as 清熱解毒, 散結消腫, 疏散風熱, 涼血解毒, 解表散風 in order to make efficacy of 清熱解毒, 散結消腫, 疏散風熱, 涼血解毒, 解表散風. The oral herbal medicine showed better efficacy and safety to improve clinical symptoms such as total efficacy, cure rate, antipyretic time, antipruritic time, scab time, anti-rash time, hospitalization period and herpes recovery time compared to the western medicine treatment. Conclusions These results show that the oral herbal medicine treatment on chickenpox in children may be more effective in reducing of clinical symptoms compared to the western medicine treatment.