• Title/Summary/Keyword: herb

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Drug-herb interactions: Mechanisms involved and clinical implications of five commonly and traditionally used herbs

  • Ong, Chin Eng;Pan, Yan
    • CELLMED
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    • v.4 no.3
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    • pp.17.1-17.8
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    • 2014
  • Herbal remedies are commonly used by patients worldwide. Because these herbal preparations share the same metabolic and transport proteins with prescribed medicines, the potential for a drug-herb interaction is substantial and is an issue of significant concern. This review paper summarizes drug-herb interactions involving inhibition or induction of cytochrome P450 enzymes, drug transporters as well as modulation of drug pharmacodynamics. An increasing number of in vitro and animal studies, case reports and clinical trials evaluating such interactions have been reported, and implications of these studies are discussed in this review. The most commonly implicated drugs in the interaction include anticoagulants, antiplatelets, immunosuppressants, anti-neoplastics, protease inhibitors, and some antidepressants. Pharmacokinetic and/or pharmacodynamic interactions of five commonly used herbal remedies (danshen, garlic, Ginkgo biloba, ginseng, and St John's wort) with these drugs are presented, with focus of discussion being the potentials for interaction, their mechanisms and clinical implications. There is a necessity for adequate pharmacovigilance to be carried out in minimizing unanticipated but often preventable drug-herb interactions.

A Study on the Herb Plant Resources in Jeonnam II. Investigation of the Herb Plant Resources around Mt. Jogho (전남지역 한약자원 식물수집분포 및 이용체계에 관한 연구 III. 조계산 한약자원 식물분포 조사)

  • 이종일
    • Korean Journal of Plant Resources
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    • v.1 no.1
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    • pp.93-116
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    • 1988
  • The plants medicinal resourees of Mt. Joghe were investigeted 10 times from January, 1988 to October, 1988. In order to analyze the vegetation of Joghemountain area, herb plants structure and distribution. Herb plants of Joghe moun-tain consisted of 102 families, 265 species in all. The resources of important herbdrugs were Gramineae, Cyperaceae Oleaceae, Araceae, Polygonaceae, Caryophyllaceae,Ranunculaceae, Theaceae, Cruciferae, Liliaceae, Rosaceae, Geranjaceae, Violaceae,Vitaceae, Umbelliferae, Labiatae, Solanaceae, Campanulaceae, Rutaceae, Compositae,Dioscoreaceae, Fagaeeae, Moraceae, Anacardiaceae, Legum inosae, Cupressaceae, andJuelandaceae. The herb drugs were comparatively more than in other mountains inour country.

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Studies on the Safety Assessment of Red-ginseng Radix Extract Solution for Herb-acupuncture (III) (약침용 홍삼추출액의 면역독성, 발열성 및 용혈성시험에 관한 연구)

  • Nam, Yun-Seok;Lee, Yun-Ho
    • Korean Journal of Oriental Medicine
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    • v.2 no.1
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    • pp.129-145
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    • 1996
  • According to the Medical Product Safety Administration Guidelines for safety assessment guinea pigs, mice and rats were used for antigenicity test, rabbits for pyrogenic test and hymolytic test. The results were summarized as follows; 1. The antigenicity test of Red-ginseng radix extract solution for herb-acupuncture did not show any anaphylatic shock but produced IgE in high dose group. 2. The result of the pyrogen test of Red-ginseng radix extract solution for herb-acupuncture was negative. 3. The result of the hemolytic test of Red-ginseng radix extract solution for herb-acupuncture were negative in low and middle dose group but was positive in high dose group.

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Analysis of the herb medications corresponded with Bi-jeung of Bangyakhappyeon(方藥合編) (《방약합편(方藥合編)》에 수록(收錄)된 비증처방(痺證處方)에 대(對)한 연구(硏究))

  • Lee, Jung-heui;Song, Tae-won;Oh, Min-seok
    • Journal of Haehwa Medicine
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    • v.10 no.1
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    • pp.375-383
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    • 2001
  • Clinically the arthritis occupies much part of musculoskeletal diseases. The arthrits is subordinate to Bi-jeung in the oriental medicine. The causes of Bi-jeung are almost proposed as Pung-Han-Sup-Yeol, and various herb medication were composed following this standard. In this paper, herb medications corresponded with Bi-jeung of Bangyakhappyeon(方藥合編) were anlysed. And the results are as follws. 1. Herb medications of Bi-jeung were composed with 4 parts, Sangtong(8 medications), Jungtong(7), Hatong(6) and Jeungbobang(7). 2. Herb medications of Bi-jeung were almost composed with Geopungsupyak, Haepyoyak(解表藥), Onryyak(溫裏藥), Boyikyak(補益藥), Yigiyak(理氣藥), and Hwalhyeol-geouhyak. 3. Analysed with a source book, Dongeuibogam was the most quotational literature.

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A study on the space programming of pharmacy department in Korean Herb Medicine Hospital (한방병원 약제부의 공간계획에 관한 연구)

  • Han, Seon-Mee;Lee, Teuk-Gu
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.7 no.2
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    • pp.15-26
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    • 2001
  • The purpose of this study is to present elementary data for space programming of pharmacy department in Korean Herb Medicine Hospital. The space composition of pharmacy department have been changed according to pharmaceutical service. In conclusion, the necessary spaces consist of medicine window, dispensary, herb medicine storeroom and decoction room. The selectable spaces consist of laboratory, processing room, manufacturing room and amenities for employees. This study suggest 2 types of space composition model according to total floor area and building scope. The location and area of pharmacy department change by means of change and growth of Korean Herb Medicine Hospital.

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A Study on the Consultation-Rooms Unit Plan of the O. P. D. in the Herb Medicine Hospital (한방병원 외래진료부 진료질의 단위공간에 관한 건축계획적 연구)

  • Yoo, Chang-Seung;Lee, Teuk-Koo
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.4 no.6
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    • pp.17-27
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    • 1998
  • After 1980's, more and more people expect to the mysterious treatment of herb medicine about chronic and degenerated disease, according to growth of income level and old population. So the herb medicine hospital is begin to increase rapidly. But, they apply western hospital plan to the herb medicine hospital project which cause a lot of problem. To solve the problem, we suggest the new design standards for the purpose of this thesis which considered treatment method and system of herb medicine hospital.

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The Effect of Local Activation Given by Sissinghurst Castle Garden in England (영국의 Sissinghurst castle garden이 주는 지역 활성화 효과)

  • 정정섭;조태동
    • Journal of Korean Society of Rural Planning
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    • v.4 no.1
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    • pp.56-62
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    • 1998
  • This study makes a general view of human-, natural environment, actual condition of use, management and administration of Sissinghurst castle garden and proposes the following directions for our model of herb industry, herb garden plan with the analysed results. 1) The location of herb garden should be selected at a place where Is close to scenic spots, sight-seeing place or big city and conveniently situated, 2) For the basic design of herb garden, the ecological features, human -, natural environment should be analysed and for the implementation of the plan, it should have variety and coordination to give the pleasure and appreciation to the users. 3) For the plan of herb garden, time limit system and number limit admission have to be introduced by calculating carrying capacity so that the user can have a comfortable atmosphere and the garden should be environment - friendly.

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Quality Characteristics of Teriyaki Sauces containing Medicinal Herb Extracts

  • Kim, Hyun-Ah;Kim, Dong-Seok;Song, Chung-Rak
    • Culinary science and hospitality research
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    • v.20 no.5
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    • pp.130-135
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    • 2014
  • This study determined the effects of addition of medicinal herb extracts (Zanthoxylum piperitum extract(TZ), Acanthopanax sessiliflorus(TA), Panax ginseng(TP), Cinnamomum lureitri Nees(TC), Angelica gigantis radix(TAG) and Crataegii fructus extract (TCF) to teriyaki sauce with regard to taste and health benefit. After adding the medicinal herb extracts to teriyaki sauce, moisture content was found to be inversely proportional to the viscosity. The sauce with Panax ginseng extract(TP) had lowest sweetness, but highest salinity. The results showed that the sauce with Korean herb extracts had lower salinity content. In terms of colour value, the sauce with Crataegii fructus extract(TCF) had much higher lightness, redness, and yellowness than sauce prepared with other herb extracts. It had the strongest acidic taste and lowest pH. Sensory evaluation test revealed that the sauce with Anthoxylum piperitum extract(TZ) was the most preferred sauce among all the sauces tested. The degree of brown color of teriyaki sauces was correlated positively with taste preference(r=.570, p<0.01) and overall preference(r=.505, p<0.01).

Comparative Study between Acupuncture and Acupuncture-Oriental Herb Medicine Treatment on Facial Nerve Paralysis (구안괘사에 대한 침구치료(鍼灸治療)와 침(鍼), 약(藥) 병용치료(竝用治療)의 비교 고찰)

  • Kim, Chil-Gab;Park, Sang-Dong;Kim, Kyung-Ho
    • Journal of Acupuncture Research
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    • v.18 no.3
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    • pp.10-22
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    • 2001
  • Objective : Many methods have been used for treatment of facial nerve paralysis. The purpose of this study was to evaluate the clinical difference between acupuncture therapy and acupuncture-oriental herb medicine therapy. Materials and Methods : From 05-01-2000 to 01-30-2001, 46 facial paralysis patients who were hospitalzed and treated more than five times at the Department of Acupuncture & Moxibustion of Dongguk University Bundang Oriental Medical Hospital were selected for two group. One group(A group) was treated by acupuncture therapy, the other group(B group) was treated by acupuncture and oriental herb medicine therapy. A group was composed of 15 patients and B group was 31 patients. Results and Conclusion : As the results of study, both acupuncture therapy and acupunture-oriental herb medicine therapy were usable for facial nerve paralysis treatment. But, we could not discover any available difference between acupuncture therapy group and acupuncture-oriental herb medicine therapy group.

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Study on a Herb pair of Pericarpium Zanthoxyli(Zanthoxyli Fructus) in 『Donguibogam』 (『동의보감(東醫寶鑑)』에 활용된 천초(川椒)(촉초(蜀椒), 화초(花椒)) 약대(藥對)에 관한 연구(硏究))

  • Yang, Yoon-Hong;Kwon, Jae-Won;Lee, Jang-Cheon;Lee, Boo-Kyun
    • Herbal Formula Science
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    • v.22 no.1
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    • pp.1-11
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    • 2014
  • Objectives : The purpose of this study is to find out herb-pair prototype composed of Pericarpium Zanthoxyli in "Donguibogam", to investigate origin of them. Methods : We researched the usages of Pericarpium Zanthoxyli compatibility as following procedure : 1. Choosing a related words such as Pericarpium Zanthoxyli(蜀椒, 川椒, 花椒) 2. Searching prescriptions: We searched prescriptions containing the related words in "Dongeuibogam" through "wook system", analyzed the selected prescription and found out herb-pair prototype composed of Pericarpium Zanthoxyli. Results : We found 12 fomulas in which Pericarpium Zanthoxyli herb pair was combinated and We made a Table 1. for the description of name of fomula, indication and herb configuration. Conclusions : Pericarpium Zanthoxyli was paired with below herbs; 檳榔(Arecae Semen), 細辛(Asari Radix), 苦楝根(Meliae Radix), 蔥白(Allii Fistulosi Bulbus), 茴香(Foeniculi Fructus), 巴豆(Crotonis Semen), 蓽撥(Piperis Longi Fructus), 露蜂房(Vespae Nidus), 肉桂(Cinnamomi Cortex), 艾葉(Artemisiae Argyi Folium), 細茶(Camellia sinensis), 雄黃(Realgar), 杏仁(Armeniacae Amarum Semen).