• Title/Summary/Keyword: hematological

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Risk assessment of Nitrogen Dioxide exposure on Welders

  • Jeong Seong-Wook;Song Seung-Hyg;Park Heung-Jai
    • Journal of Environmental Science International
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    • v.14 no.1
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    • pp.9-14
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    • 2005
  • This study evaluated the hazard caused by $NO_{2}$, an oxidant generated in the process of welding. We com­pared hematological and biochemical parameters in workers who chronically inhale $NO_{2}$ and office workers not exposed to $NO_{2}$. $NO_{2}$ exposure affected the hematological and biochemical parameters. Increasing $NO_{2}$ concen­trationincreased the number of leukocytes, while decreasing the number of erythrocytes. Blood urea nitrogen, cre­atinine, uric acid, and lactate dehydrogenase were increased, while total protein and triglycerides were decreased. The mean concentration of $NO_{x}(NO_{2}^{-}/NO_{3}^{-})$ in the serum of welders and the control group was $35.97{\pm}2.85\;and\;55.40{\pm}5.81\;{\mu}mol/L,$ respectively. The difference was significant (p < 0.05), although $NO_{2}^{-}$ was not detected in the serum.

Effect of Korean Red Ginseng and Western Ginseng on Body Temperature, Pulse Rate, Clinical Symptoms and the Hematological Changes in Human (고려홍삼과 서양삼이 사람의 체온, 맥박수, 임상증상 및 혈액학적 변화에 미치는 영향)

  • 김성훈;이상룡
    • Journal of Ginseng Research
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    • v.19 no.1
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    • pp.1-16
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    • 1995
  • Effects of Korean red ginseng (KG) and western ginseng (WG) on body temperature, pulse rate, clinical symptoms and hematological changes in human were studied after administration p.o. with Korean red ginseng and western ginseng for 10-days. KG was more effective in keeping homeostsis in than western ginseng in the changes of body temperature and pulse rate. KG was more effective in low body temperature and SOEVMIN (소음인), while inducing tachycardia especially in SOYANGIN (소양인) and TAEEUMIN (태음인). WG tended to drop temperature abruptly and also descended pulse rate with greater range than KG. KG and WG could cause side effects such as headache and gastrointestinal syndromes and induce hypertension or hypotension abruptly in specific constitutions. However, KG and WG did not cause abnormal changes in urinalysis and hematology.

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Quetiapine Induced Autoimmune Hemolytic Anemia in a Child Patient: A Case Report

  • Arici, Asiye;Altun, Hatice;Acipayam, Can
    • Clinical Psychopharmacology and Neuroscience
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    • v.16 no.4
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    • pp.501-504
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    • 2018
  • Autoimmune hemolytic anemia is a disease characterized with destruction of erythrocytes as a result of antibody produce against patient's own erythrocytes and anemia. Autoimmune hemolytic anemia can be roughly stratified into two groups according to serological features and secondary causes including drugs induced hemolytic anemia. Drugs induced autoimmune hemolytic anemia is very rare in pediatric patients. Even though hematological side effects such as leucopenia, agranulocytosis, eosinophilia, thrombocytopenic purpura and aplastic anemia might occur due to psychotropic drug use; to the best of our knowledge there is no autoimmune hemolytic anemia case due to quetiapine, an atypical antipsychotics, in literature. We hereby describe the first child case of autoimmune hemolytic anemia during quetiapine treatment.We also are pointing out that one should keep in mind serious hematological side effects with atypical antipsychotic drug use with this case report.

실험동물 마우스의 혈액세포 분포에 관한 연구

  • Ian C. Guest
    • Toxicological Research
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    • v.7 no.1
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    • pp.47-50
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    • 1991
  • Hematological studies in two strains of normal laboratory mice, namely ICR and ddY which were produced in Koren were carried out. Blood analysis was performed by using different methods, a fully automated analyzer (ELT 1, 500), Coulter counter (model S plus IV) and manual technique to examine possible differences resulting from methodolgies'slight differences among the values of blood parameters were obtained. There was a slight difference noted between sexes, however, similar values were obtained from both strains.

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A Comparative study on hematological values and plasmaprotein by school lunch. (학교급식에 따른 혈액상 및 혈장 단백질량의 비교 분석)

  • Choi, H.M.;Shin, K.S.;Han, Y.I.;Rha, D.J.
    • Journal of Environmental Health Sciences
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    • v.3 no.1
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    • pp.45-47
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    • 1976
  • A survey was carried out in order to figure out of phenomenon by school feeding from June 1973 to May 1974. Hematological values and plasma protein of 94 boys and 91 girls (total 185 students)were studied. As the results of this survey, the following conclusions were obtained. 1. Hemoglobin, hematocrit, mean corpuscular hemoglobin concentration of boys and girls were increased after school lunch. 2. Plasma protein of boys and girls were clearly increased after school lunch.

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The Effects of Toosendan fructus(TOF) treatment on Hematological and Cyto-pathological Alterations in Non-Bacterial Prostatitis Rat Model (천련자가 만성 비세균성 전립선염 Rat 모델에서 혈액 및 세포조직의 변화에 미치는 영향)

  • Cho, Chung-Sik;Lee, Koo-Hyen;Chang, Sun-Kyu;Choi, Jeong-Sik;Kim, Cheol-Jung
    • The Korea Journal of Herbology
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    • v.22 no.4
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    • pp.145-153
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    • 2007
  • Objective : Although chronic non-bacterial prostatitis is a common disease, it is very difficult to treat effectively. Toosendan fructus(TOF) has been traditionally used in treatment of abdominal pain and parasite. In this study, we investigated the therapeutic effects and action mechanism of Toosendan fructus (TOF) in the rat model of non-bacterial prostatitis induced by castration and testosterone treatment. Method : Eight-month-old rats were treated with $17{\beta}$-estradiol after castration for induction of experimental non-bacterial prostatitis, which is similar to human chronic prostatitis in histophatological profiles. Toosendan fructus(TOF) and testosterone were administered as an experimental specimen and a positive control, respectively. The prostates were evaluated by histopahological parameters including the epithelial score and epithelio-stromal ratio for glandular damage. Also, the prostates were observed by hematological alterations of WBC, RBC, hemoglobin, hematocrit and platelet. Results : While prostates of control rats revealed severe acinar gland atrophy and stromal proliferation, the rats treated with Toosendan fructus(TOF) showed a diminished range of the tissue damage. Epithelial score was improved in Toosendan fructus(TOF) than that of the control. The epithelio-stromal ratio was lower in Toosendan fructus(TOF) when compared to that of the control. Also, the examination of bloods were not observed hematological change. Conclusions : These findings suggest that Toosendan fructus(TOF) may protect the glandular epithelial cells and may take hematological safety. We concluded that Toosendan fructus(TOF) may could be a useful remedy agents for treating the chronic non-bacterial prostatitis.

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Documentation of Physiological Parameters and Blood Profile in Newly Born Kajli Lambs

  • Saddiqi, H.A.;Nisa, M.;Mukhtar, N.;Shahzad, M.A.;Jabbar, A.;Sarwar, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.7
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    • pp.912-918
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    • 2011
  • Newly born lambs have to face challenges in a new environment totally different from that of the uterus. Adaptation to extra-uterine life involves functional changes with almost each organ and system in the body undergoing a series of metabolic and anatomical modifications. Failure to adapt the extra-uterine environment can not only lead to homeostatic disturbances but also lead to the death of the affected lambs. Hematological parameters of newly born lambs show variability that differs between breeds of lambs. The purpose of present study was to determine homeostatic responses and physiological reference values in Kajli breed lambs occurring in the neonatal period through changes in blood profile, respiratory rate, heart rate, live weight and rectal, scrotal and skin temperatures. For this purpose, sixteen clinically fit lambs (males = 10 and females = 6) with a mean body weight $6.92{\pm}0.46$ kg were selected. Physiological data of selected parameters of each Kajli lamb was recorded at three day intervals and hematological parameters at five days for a period of 30 days. In general, statistical analysis showed a significant effect of time (p<0.001) on all the studied physiological and hematological parameters except platelets counts, white blood cells and hemoglobin concentration. The results documented in the current study are an addition to existing knowledge of the physiology of Kajli sheep breed should be helpful in developing feeding, disease diagnoses and treatment protocols for newborn Kajli stock.

Comparison of Hematological Properties in Cultured Olive Flounder Paralichthys olivaceus on Different Growth Stages and Seasons (양식넙치 Paralichthys olivaceus의 성장단계별, 계절별 혈액학적 성상비교)

  • Kim, Won-Jin;Kim, Young-Soo;Chang, Young-Jin
    • Development and Reproduction
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    • v.14 no.2
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    • pp.131-141
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    • 2010
  • This study was conducted to examine the hematological factors in cultured olive flounder Paralichthys olivaceus depending on its growth stage and season. The study also aims at developing the standard hematological indicator for growth stage and season by examining total 16 parameters including whole blood (hematocrit, red blood cell and hemoglobin), biochemical (glucose, cholesterol, total protein, AST, ALT, $Na^+,\;K^+,\;Cl^-,\;Ca^{2+},\;Mg^{2+}$ and osmolarity), and endocrine (cortisol and $T_3$) factors in plasma of cultured olive flounder. The result showed a growth stage-dependent increase of $T_3$ level in olive flounder while the level of cholesterol showed an inverse correlation to fish size. For seasonal fluctuation in cultured olive flounder of the same growth stage, the highest level of Ht and RBC was observed in autumn.

Effects of Salinity on Survival, Oxygen Consumption, and Hematological Response of Greenling Hexagrammos otakii (쥐노래미(Hexagrammos otakii)의 생존율, 산소 소비율과 혈액 성상에 미치는 염분의 영향)

  • Oh, Sung-Yong;Myoung, Jung-Goo;Park, Jin Woo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.48 no.5
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    • pp.712-718
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    • 2015
  • The effects of salinity on survival, oxygen consumption, and hematological response of greenling Hexagrammos otakii, mean body weight 147.1±3.8 g, were investigated under salinity conditions of 33.4 (control), 33.1, 32.8, 32.2, 31.0, 28.7, 23.9, 14.5, and 3.8 psu, to evaluate physiological effects in relation to changes in salinity. The survival and hematological responses of fish were measured at each salinity after 96- and 24-h exposures. The oxygen consumption rate (OCR) of fish was measured in triplicate under conditions of stepwise salinity exposure (33.4→33.1→32.8→32.2→31.0→28.7→23.9→14.5→3.8 psu) with an interval of 24 h at each salinity, using a continuous flow-through respirometer. No fish mortality was observed in the range of 33.4 to 14.5 psu, but the survival rate was reduced to 53.3% at 3.8 psu after 96 h of exposure. The OCRs did not significantly differ in the range between 33.4 to 28.7 psu (P>0.05), but significantly increased at 23.9 and 14.5 psu, and then dramatically decreased at 3.8 psu compared to the control (P<0.05). Hematological variables, such as glucose, glutamic pyruvic transaminase (GPT), hematocrit, and Na+, were affected by reduced salinity. This result may be applicable for habitat and culture management of greenlings.