• Title/Summary/Keyword: hematocrit

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Effects of Commercial Soy Milk and Cow Milk on Iron Status and Work Capacity of Rats (시판 두유 및 우유가 흰쥐의 체내 철분 영양상태와 운동능력에 미치는 영향)

  • 이윤복
    • Journal of Nutrition and Health
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    • v.30 no.8
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    • pp.904-910
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    • 1997
  • Evaluation of soy milk as an iron-rich milk substitute was conducted by feeding commercial soy milk , cow milk and mixed formula(soy and cow milk) to Wistar rats for 8 weeks. Body weight gains were significantly lower in the soy milk and mixed formula groups. Hematocrit, serum iron concentration and TIBC (total iron binding capacity) were measured to determine the iron status of the rats. In these respects, the iron status of the soy milk group was normal. Both serum iron concentration and TIBC as well as hematocrit were abnormal in the cow milk group , which is indictive of severe iron deficiency . Although hematocrit was normal in the mixed formula group, serum iron concentration was lightly low. The work capacities of each group were correlated with serum iron concentration and tIBC rather than hematocrit. The running distance of the soy milk group was about 10 -fold longer than that of the cow milk group. Soy milk may be considered an iron- rich substitute for cow milk due to its higher iron content and bioavailability.

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Noninvasive Hematocrit Monitoring Based on Parameter-optimization of a LED Finger Probe

  • Yoon, Gil-Won;Jeon, Kye-Jin
    • Journal of the Optical Society of Korea
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    • v.9 no.3
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    • pp.107-110
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    • 2005
  • An optical method of measuring hematocrit noninvasively is presented. An LED Light with multiple wavelengths was irradiated on fingernail and transmitted light from the finger was measured to predict hematocrit. A finger probe contained an LED array and detector. Our previous experience showed that prediction accuracy was sensitive to reliability of the finger probe hardware and we optimized the finger probe parameters such as the internal color, detector area and the emission area of a light source based on Design of Experiment. Using the optimized finger probe, we developed a hematocrit monitoring system and tested with 549 persons. For the calibration model with 368 persons, a regression coefficient of 0.74 and a standard deviation of 3.67 and the mean percent error of $8\%$ were obtained. Hematocrits for 181 persons were predicted. We achieved a mean percent error of $8.2\%$ where the regression coefficient was 0.68 and the standard deviation was 3.69.

Hemorheological measurements in experimental animals: further consideration of cell size - pore size relations in filtrometry

  • Nemeth, Norbert;Baskurt, Oguz K.;Meiselman, Herbert J.;Furka, Istvan;Miko, Iren
    • Korea-Australia Rheology Journal
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    • v.21 no.3
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    • pp.155-160
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    • 2009
  • Micropore filtration of dilute red blood cell (RBC) suspensions is a widely known method for determining red blood cell deformability. Use of this method for cells from various laboratory animal species does require considering the effects of the cell size to pore size ratio and of suspension hematocrit. In general, previous animal studies have utilized 5% hematocrit suspensions and five micron pores, and thus conditions similar to human clinical laboratory practice. However, when used for repeated sampling from small laboratory animals or for parallel multiple samples from different sites in large laboratory animals, the volume of blood sampled and hence the hematocrit of the test suspension may be limited. Our results indicate that hematocrit levels yielding stable values of RBC pore transit time are pore size and species specific: three micron pores = $2{\sim}5%$ for dog and $3{\sim}5%$ for rat; five micron pores $3{\sim}5%$ for dog and $1{\sim}5%$ for rat. An analytical approach using a common expression for calculating transit time is useful for determining the sensitivity of this time to hematocrit alterations and hence to indicate hematocrit levels that may be problematic.

Blood Picture of Race Horses in Korea (경주마(競走馬)의 혈액상(血液像)에 관(關)하여)

  • Kim, Tae Jong;Lee, Kang Wook
    • Korean Journal of Veterinary Research
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    • v.14 no.2
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    • pp.179-184
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    • 1974
  • The blood picture of 85 healthy race horses in Korea was investigated. The ranges and mean values of erythrocyte, hemoglobin, hematocrit value, mean corpuscular volume, mean corpuscular hemoglobin concentration, and total white blood cell count in the blood picture were determine. The respective mean value and standard deviation and age differences were as follows: 1. The erythrobyte count was shown as range of 6.20 to $11.32{\times}10^6/mm^3$ with mean of $8.61{\pm}1.92{\times}10^6/mm^3$(SD). The leucocyte count was shown as range 5.0 to $18.0{\times}10^3/mm^3$ with mean of $8.25{\pm}1.51{\times}10^3/mm^3$(SD). There were not significant. differences in age, 2. The mean value of hemoglobin was shown $13.9{\pm}1.7g/100ml(SD)$ ranging 9.8 to 16.8g/100ml. The mean value of hematocrit was shown $40.9{\pm}3.94ml/100ml(SD)$ ranging 26 to 54. There were not significant differences in age. 3. The mean corpuscular hemoglobin was shown as range of 11.8 to 22.2pg with mean of $16.9{\pm}4.69$(SD). The mean corpuscular volume was shown as range of 34.5 to $71.3cu{\mu}$ with mean of $49.0{\pm}7.32cu{\mu}$(SD). The mean corpuscular hemoglobin concentration was shown as range of 30.6 to 39.4 g/100 ml with mean of $34.6{\pm}2.36$(SD). There were not significant differences in age. 4. The correlation among erythrocyte count, hemoglobin and hematocrit value were observed as follows: Erythrocyte count and hemoglobin (+0.328), rythrocyte count and hematocrit vague (+0.319). A linear regression equation was shown as follows: Erythrocyte count and hemoglobin (Y=0.336x+10.977), erythrocyte count and hematocrit value (Y=0.655x+35.274). 5. The high correlation between hemoglobin and hematocrit vague was observed (r= +0.836). A linear regression equation was shown: (Y=1.948x+13.895).

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AVAILABILITY OF AUTOLOGOUS TRANSFUSION IN BILATERAL SAGITTAL SPLIT RAMUS OSTEOTOMY FOR MANDIBULAR PROGNATHISM (하악전돌증 환자의 하악지 시상분할 골절단술에서 자가수혈의 유용성)

  • Han, Sang-Jeong;Zang, Ju-Min;Oh, Han-Seok;Lee, Hae-Kyung;Lee, Jeong-Nyeo;Lee, Su-Woon;Park, Sang-Jun;Kim, Woo-Hyung
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.5
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    • pp.524-529
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    • 2007
  • Objective: Autologous transfusion is frequently used with orthognathic surgery. The necessity of autologous transfusion has begun to question alone in bilateral sagittal split ramus osteotomy. The aim of this study was to evaluate the availability of autologous transfusion. Methods: The chart reviews of sixty patients who had undergone bilateral sagittal ramus osteotomy were done. The subjects were divided into two groups: In experimental group, 30 patients who autodonated 320ml in the preoperative 3 weeks actually received a transfusion in the postoperative 6 hours were included. In control group, 30 patients who underwent the same operation without preoperative donation and any other transfusion were included. Hemoglobin, hematocrit, and changes of these values in both groups were evaluated. Results: 1. From postoperative 3 hours to postoperative 1 day, the increases of hemoglobin(0.8g/dL in experimental group, 0.2g/dL in control group) and hematocrit(0.3% in experimental group, 0.6% in control group) were not statistically significant between both groups. 2. From postoperative 1 day to postoperative 1 week, the increase of hemoglobin(0.6g/dL in experimental group, 0.3g/dL in control group) was not statistically significant between both groups. But the increase of hematocrit(2.5% in experimental group, 1.0% in control group) was statistically significant between both groups over the same period(hematocrit p=0.043). 3. On postoperative 1 week, the values of hemoglobin(12.3% in both groups) and hematocrit(35.6% in experimental group, 36.8% in control group) were not statistically significant between both groups. Conclusion: The autologous transfusion in surgery of just a little blood loss was not effective. The most results show that there is little availability of autologous transfusion according to changes of hemoglobin and hematocrit in bilateral sagittal split ramus osteotomy.

Effects of Ojeoksan extracted by varied extraction method in HA-induced model of blood stasis (煎湯方法의 變化에 의한 五積散 물추출액이 Hydrocortisone acetate로 유발한 瘀血病態에 미치는 효과)

  • Seo, Bu-Il;Kim, Mi-Ryeo;Park, Ji-Ha;Ji, Seon-Yeong
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.14 no.1
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    • pp.182-189
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    • 2001
  • This study was performed to compare the effect of Ojeoksan which have extracted by varied extractor(press extractor : PE, pressless extractor : PLE, short acting extractor : SE) on model of blood stasis in rats, Except for the normal group, hydrocortisone acetate(HA;25mg/kg in ethanol. IM) to induce experimental blood stasis model for 1 weeks and each extract of Ojeaksan was administrated after 1hr following HA injection for 1week. We measured the hematocrit, the platelet count, the prothrombin time, levels of fibrinogen in rats' blood, The sample Ⅰ(Ojeoksan extracted by PE) group showed significant decrease of hematocrit. prothrombin time and significant increase of the platelet count, levels of fibrinogen in comparison with those of the control group, The sample Ⅱ(Ojeaksan) extracted by PLE) group showed significant decrease of hematocrit and significant increase of levels of fibrinogen in comparison with those of the control group. Administration of the sample Ⅲ(Ojeaksan extracted by SE) group showed significant decrease of hematocrit and significant increase of the platelet count, levels of fibrinogen in comparison with those of the control group.

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The Usefullness of Percutaneous Transarterial Embolization in Patients with Severe Multiple Traumas (다발성 손상에 의한 중증외상환자의 경피적 동맥색전술의 유용성)

  • You, In-Gyu;Lim, Cheong-Hwan
    • Journal of the Korean Society of Radiology
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    • v.6 no.2
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    • pp.107-114
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    • 2012
  • The study was conducted in patients who had undergone angiography and arterial embolization after being diagnosed with arterial bleeding among those registered with severe trauma at the admission to the department of emergency due to accidents. In the study, comparison was done between the survived group and the nonsurvived group to investigate the usefulness and the optimal performance timing of angiography and embolization as the survival-affecting factors and treatment methods for patients. The study was performed as a retrospective analysis in 45 patients who had undergone angiography and arterial embolization among those categorized as severe trauma patients from the emergency department of H hospital located in Gyeonggi-do from July, 2006 until December, 2010. The Injury Severity Score (ISS), the Revised Trauma Score (RTS), the hematocrit were the main outcome measurements. Arterial embolization was technically successful in all cases, transcatheter arterial embolization of arterial bleeding is a useful procedure in lowering the mortality and complication in severe trauma patients. and RTS, ISS, Hematocrit were the predictable early mortality factors. So bad vital sign patients must be progressed rapidly.

Effects of Quercetin and Mannitol on Erythropoietin Levels in Rats Following Acute Severe Traumatic Brain Injury

  • Kalemci, Orhan;Aydin, Hasan Emre;Kizmazoglu, Ceren;Kaya, Ismail;Yilmaz, Hulya;Arda, Nuri M
    • Journal of Korean Neurosurgical Society
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    • v.60 no.3
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    • pp.355-361
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    • 2017
  • Objective : The aim of this study to investigate the normal values of erythropoietin (EPO) and neuroprotective effects of quercetin and mannitol on EPO and hematocrit levels after acute severe traumatic brain injury (TBI) in rat model. Methods : A weight-drop impact acceleration model of TBI was used on 40 male Wistar rats. The animals were divided into sham (group I), TBI (group II), TBI+quercetin (50 mg/kg intravenously) (group III), and TBI+mannitol (1 mg/kg intravenously) (group IV) groups. The malondialdehyde, glutathione peroxidase, catalase, EPO, and hematocrit levels were measured 1 and 4 hour after injury. Two-way repeated measures analysis of variance and Tukey's test were used for statistical analysis. Results : The malondialdehyde levels decreased significantly after administration of quercetin and mannitol compared with those in group II. Catalase and glutathione peroxidase levels increased significantly in groups III and IV. Serum EPO levels decreased significantly after mannitol but not after quercetin administration. Serum hematocrit levels did not change significantly after quercetin and mannitol administration 1 hour after trauma. However, mannitol administration decreased serum hematocrit levels significantly after 4 hour. Conclusion : This study suggests that quercetin may be a good alternative treatment for TBI, as it did not decrease the EPO levels.

Non-invasive hematocrit measurement (혈액중 non-invasive hematocrit 분석)

  • Yoon, Gil-Won;Jeon, Kye-Jin;Park, Kun-Kook;Lee, Jong-Youn;Hwang, Hyun-Tae;Yeo, Hyung-Seok;Kim, Hong-Sig
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2002.11a
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    • pp.59-62
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    • 2002
  • Wavelength selection and prediction algorithm for determining hematocrit are investigated. A model based on the difference in optical density induced by the pulsation of heart beat is developed by taking approximation of Twersky's theory on the assumption that the variation of blood vessel size is small during arterial pulsing[1]. A device is constructed with a five-wavelength LED array as light source. The selected wavelengths are two isobestic points and three in compensation for tissue scattering. Data are collected from 549 out-patients who are randomly grouped as calibration and prediction sets. The range of percent hematocrit was 19.3∼51.8. The ratio of the variations of optical density between systole and diastole at two different wavelengths is used as a variable. We selected several such variables that show high reproducibility among all variables. Multiple linear regression analysis is made. The relative percent error is 8% and the standard deviation is 3.67 for the calibration set. The relative % error and standard deviation of the prediction set are 8.2% and 3.69 respectively. We successfully demonstrate the possibility of non-invasive hematocrit measurement, particularly, using the wavelengths below 1000nm.

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A Study on, Iron Nutritional Status and Anemia of Middle School Girls in Ulsan Metropolitan City

  • Hong, Soon-Myung;Hwang, Hye-Jin;Kim, Hyun-Hee
    • Journal of Community Nutrition
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    • v.6 no.2
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    • pp.86-90
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    • 2004
  • This study was designed to assess the iron nutritional status and anemia of middle school girls in Ulsan City, who were evaluated with a questionnaire, measurement of hematological indices. The average height and weight of respondents were 154.81$\pm$6.28cm and 48.51$\pm$8.80kg, respectively. Mean daily energy intake was 1815.72$\pm$328.04kcal and iron intake was 15.13$\pm$4.50mg. The average hemoglobin concentration of subjects was 11.98$\pm$0.78g/dl, and the average hematocrit level was 36.62$\pm$2.21%. Transferrin saturationTS (%) was 25.58$\pm$9.82%, and the ferritin level was 40.45$\pm$23.03ng/ml. Iron deficiency anemia among the subjects was estimated as 54.2% by using hemoglobin(<12g/이), 33.9% by hematocrit (<36%). The clinical symptoms relating anemia were measured with 4 Likert scale (1 : never, 4 : often), 'tired out easily (2.34$\pm$0.92)' was the highest, followed by 'feel dizzy always (2.26$\pm$0.85)', 'decreasing ability to concentrate (2.23$\pm$0.77)', 'get a cold easily (2.19$\pm$0.82)', 'have a headache (2.10$\pm$0.79)', 'poor memory (2.09$\pm$0.83)', 'no appetite (1.99$\pm$0.85)', As for the correlation between iron parameter and clinical symptoms related to anemia, the hematocrit rate was negatively correlated with 'get a cold easily', 'pale face', 'feeling blue', 'difficult digestion' (p<0.05). The level of iron was negatively correlated with 'tired out easily', 'get a cold easily' (p<0.05) and TS (%) were negatively correlated with 'tired out easily (p<0.05)', 'get a cold easily (p<0.01). Our study resulted that the prevalence of a iron deficiency of a middle school girl is very high, therefore the guidelines for iron supplementation and nutritional education to improve their iron status should be provided.