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http://dx.doi.org/10.3807/JOSK.2005.9.3.107

Noninvasive Hematocrit Monitoring Based on Parameter-optimization of a LED Finger Probe  

Yoon, Gil-Won (Department of Electronic & Information, Seoul National University of Technology)
Jeon, Kye-Jin (u-Health Project Team, Samsung Advanced Institute of Technology Kiheung)
Publication Information
Journal of the Optical Society of Korea / v.9, no.3, 2005 , pp. 107-110 More about this Journal
Abstract
An optical method of measuring hematocrit noninvasively is presented. An LED Light with multiple wavelengths was irradiated on fingernail and transmitted light from the finger was measured to predict hematocrit. A finger probe contained an LED array and detector. Our previous experience showed that prediction accuracy was sensitive to reliability of the finger probe hardware and we optimized the finger probe parameters such as the internal color, detector area and the emission area of a light source based on Design of Experiment. Using the optimized finger probe, we developed a hematocrit monitoring system and tested with 549 persons. For the calibration model with 368 persons, a regression coefficient of 0.74 and a standard deviation of 3.67 and the mean percent error of $8\%$ were obtained. Hematocrits for 181 persons were predicted. We achieved a mean percent error of $8.2\%$ where the regression coefficient was 0.68 and the standard deviation was 3.69.
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1 R. McNichols and G. L. Cote, 'Optical glucose sensing in biological fluids : an overview,' J. Biomedical Optics, vol. 5, no. 1, pp. 5-16, 2000   DOI   ScienceOn
2 J.G. Webster ed., Design of Pulse Oximeters, (Institute of Physics Publishing, Bristol and Philadelphia, 1997), pp. 124-143
3 S. Yasuda, S. Itoh, K. Isobe, et al., 'New transcutaneous jaundice device with two optical paths,' J. Perinat. Med., vol. 31, pp. 81-88, 2003   DOI   ScienceOn
4 K.J. Jeon, S-J Kim, K.K. Park, J-W Kim, and G. Yoon, 'Noninvasive total hemoglobin measurement,' J. of Biomedical Optics, vol. 7, no. 1, pp. 45-50, 2001   DOI   ScienceOn
5 S. Hahn, G. Yoon, G. Kim, and S-H Park, 'Reagentless determination of human serum components using infrared absorption spectroscopy,' Journal of the Optical Society of Korea, vol. 7, no. 4, pp. 240-244, 2003   과학기술학회마을   DOI   ScienceOn
6 C. Choi, K-S Soh, S.M. Lee, and G. Yoon, 'Propagation of light along an Acupuncture meridian,' Journal of the Optical Society of Korea, vol. 7, no. 4, pp. 245-248, 2003   과학기술학회마을   DOI   ScienceOn
7 R. F. Schmidt and G. Thews eds. Human Physiology, (Springer-Verlag Berlin Heidelberg, 1993), Chapt. 18
8 S. M. Hopfer, F.L. Nadeau, M. Sundra, and G. S. Makowski, 'Effect of protein on hemoglobin and hematocrit assays with a conductivitity-based point-of-care testing device : comparison with optical methods,' Annals of clinical & Laboratory Science, vol. 34, pp. 75- 82, 2004
9 H. Kanashima, T. Yamane, T. Takubo, T. Kamitani, and M. Hino, 'Evaluation of noninvasive hemoglobin monitoring for hematological disorders,' J. of Clin. Lab. Anal., vol. 19, pp. 1-5, 2005   DOI   ScienceOn
10 D. Dvir, D. Geva, O. Amir, I. Fine, E. Moanshkin, G. Fostick, and E. Segal, 'Evaluation of a noninvasive hemoglobin and hematocrit monitoring device,' Critical Care, vol. 9, suppl 1, P333, 2005   DOI   ScienceOn
11 G. Yoon, S-J Kim, K. J. Jeon, 'Robust design of finger probe in non-invasive total haemoglobin monitor,' Medical & Biological Engineering & Computing, vol. 43, no. 1, pp. 121-125, 2005   DOI   ScienceOn
12 V. Twersky, 'Absorption and multiple scattering by biological suspensions,' J. Opt. Soc. Am., vol. 60, pp. 1084-1093, 1970   DOI
13 O.Wieben, Saturation versus normalized ratio, J.G. Webster ed., Design of Pulse Oximeters, (Institute of Physics Publishing, Bristol and Philadelphia, 1997), chapter 4.4