• 한국보건간호학회지
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• 제26권1호
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• pp.101-112
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• 2012

Purpose: The purposes of this study were to identify differences of duties, tasks, and task elements of care helpers between long term care (LTC) facilities and client's home (CH), and to provide data for the development of educational programs and policies. Methods: This study was a descriptive investigation; the subjects of the study were 418 care helpers. Duties, tasks, and task elements were measured using the framework proposed by Shin et al. (2012). Data were analyzed by t-test using PASW 18.0. Results: All of the jobs were statistically significant differences between LTC and CH. Dietary assistance and Daily work assistance were more frequently in CH, and the frequency of other tasks was higher in LTC than CH. Tasks with higher-reported difficulty by those who worked in LTC were as follows: personal hygiene, position change and movement, exercise and activity assistance, safety care, communication assistance, dietary assistance, environment management, daily work assistance, emergency prevention, early detection and speedy reporting, and dementia patient care. Conclusion: These findings suggest that training for care helpers of each facility type will be differentiated. Tasks and task elements reported by care helpers were modified and added to the standard textbook.

• 한국정보통신학회논문지
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• 제21권8호
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• pp.1498-1507
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• 2017

최근 발표에 따르면, 2020년까지 모바일 데이터 트래픽이 현재의 11배까지 증가 될 것으로 예상된다. 그 중 비디오 트래픽이 70%를 차지할 것으로 예상되는 만큼 방대해지는 모바일 비디오 트래픽의 문제를 해결하기 위해서는 비디오 트래픽의 특성을 이해할 필요가 있다. 최근, 인기 있는 유튜브 비디오와 같은 일부 인기 있는 콘텐츠의 반복적인 요청으로 인해 네트워크 트래픽 오버헤드가 많이 발생한다. 만약 콘텐츠 인기도를 알고 인기 있는 콘텐츠를 미리 캐싱 할 수 있는 네트워크 노드를 구성한다면 이용자의 요청에 대해 캐싱 된 콘텐츠를 이용함으로써 네트워크 오버헤드를 줄일 수 있다. 장치 대 장치 통신, 멀티캐스트, 헬퍼를 통해 비디오 처리량이 기존의 방법보다 약 1.5배에서 2배의 이득이 향상되었다. 또한, 프리픽스 캐싱을 통해 기존의 방법보다 약 0.2배에서 0.5배의 재생 지연이 감소되었다. 본 논문에서는 무선 네트워크 환경에서 콘텐츠 인기도를 기반한 캐싱 기술에 대한 최신 연구를 소개 한다.

• 대한의생명과학회지
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• 제24권2호
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• pp.94-101
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• 2018

Tuberculosis (TB) is infectious disease caused by Mycobacterium tuberculosis (MTB) infection. It is known that not only the property of microorganism but also the genetic susceptibility of infected patients is controlled. Interleukin 2 (IL-2) is a cytokine belonging to type 1 T helper (Th1) activity. In addition, IL-2, when infected with MTB, binds IL-2 receptor and promotes T cell replication and is involved in granuloma formation. The aim of this study was to investigate the genetic polymorphisms of the IL-2 receptor gene in tuberculosis patients and normal individuals. We analyzed 22 SNPs in three genes using the genotype data of 443 tuberculosis cases and 3,228 healthy controls from the Korea Association Resource for their correlation with tuberculosis case. IL2RA, IL2RB, and IL2RG genes were genotyped of 16, 4, and 2 SNPs, respectively. Among three genes, only IL2RA gene polymorphisms showed statistically significant association with tuberculosis case. 6 SNPs with high significance were identified in the IL2RA gene. In addition, the linkage disequilibrium (LD) structure of IL2RA gene was confirmed. SNP imputation of IL2RA gene was performed, it was confirmed that more SNPs were significant between case and control. If we look at the results of IL2RA gene analysis above, we can see that genetic polymorphism in the gene expressing $IL-2R{\alpha}$ will regulate the expression level of $IL-2R{\alpha}$, and the change in the immune system involved in $IL-2R{\alpha}$. In this study, genetic polymorphism that may affect host immunity suggests that susceptibility to tuberculosis may be controlled.

• 한국지역사회생활과학회지
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• 제18권3호
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• pp.369-378
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• 2007

This study purposed to examine elderly welfare facilities by type, to analyze their local variations, and ultimately to contribute to the expansion of elderly welfare infrastructure. The results are expected to help inspect elderly welfare infrastructure for providing the aged with social services before the execution of 'the insurance for elderly long term care' and establish welfare facilities by area in the future. For these purposes, we used the national data "The Current State of Elderly Welfare Facilities in 2007" produced by the Ministry of Health and Welfare. We digitized elderly welfare facilities in 163 cities and counties by type and analyzed them by area. We also examined the differences in the local distribution of representative elderly welfare facilities such as elderly welfare centers, home based facilities (home helper centers), asylums for the aged and elderly care facilities in 16 cities and provinces. Furthermore, we analyzed differences and problems in their local distribution urban areas, mixed areas of urban and rural communities, and rural areas. In addition, we studied the current state of institutionalized care and home based care, which are two major directions of current elderly welfare policies, based on the local distribution of facilities and analyzed differences in the trends according to area. According to these results, the urban had more home based care facilities than the rural. However, the rural had more institutionalized care facilities than urban. Also, each local self-governing body showed unique characteristics. Therefore, these results suggest that we need to establish elderly welfare policies based on the distribution of facility types by area.

• 한국콘텐츠학회논문지
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• 제15권10호
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• pp.193-204
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• 2015

본 연구는 노인장기 요양 서비스 과정에서 행하게 되는 요양보호사의 노인차별이 노인학대에 미치는 영향을 확인하고, 노인차별과 노인학대의 인과관계에서 공적 기관 상담의 매개 효과를 규명하기 위해 시도한 연구이다. 경상남도에 있는 노인장기 요양기관에 근무하는 요양보호사 627명을 대상으로 구조화된 설문지를 사용하여 자료를 수집하였으며, Baron과 Kenny(1986)의 방법에 의해 다중회귀분석을 이용하여 분석하였다. 노인차별이 노인학대에 유의한 영향을 미치고 있었으며, 분석결과 공적 기관 상담이 노인차별과 노인학대의 관계상에서 유의한 부분 매개 효과가 있는 것으로 나타났다. 이러한 연구결과를 바탕으로 노인차별에 따른 노인학대를 공적 기관 상담을 통하여 감소시킬 수 있다는 것을 확인하였으며, 노인차별과 공적 기관 상담에 대한 몇 가지 실천적 함의를 제시하였다.

• 동의신경정신과학회지
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• 제15권2호
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• pp.89-101
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• 2004

Objective : The present experiments were designed to study on the immune-enhancing effect of Mountain grown ginseng, Mountain cultivated ginseng, and Panax ginseng Method : In order to compare the immune-enhancing effect of moutain grown ginseng, moutain cultivated ginseng and Panax ginseng, the study was done through the forced swimming test (FST), measurement of T helper Th1, Th2 cytokines and fatigue related factors. Result : Moutain grown ginseng and panax ginseng decreased the immobility time in the FST compared to the control. Glucose, blood urea nitrogen (BUN), creatinine, lactate dehydrogenase (LDH) and Total-protein (T-protein) in serum were investigated. The serum achieved from ginseng administered mouse showed higher BUN, T-protein than the control. moutain grown ginseng administered group showed lower LDH than the control group. moutain grown ginseng administered mouse showed higher glucose than the control. Creatinine was same in either experimental or control group. Ginseng-induced cytokine production in human T-cell line, MOLT-4 cells and mouse peritoneal macrophages were compared. Moutain cultivated ginseng (10-4 dilution) and panax ginseng (10-3 dilution) were increased the interferon $IFN-{\gamma}$ production compared with media control (about 1.6-fold P<0.05) at 48 h. Moutain grown ginseng (10-4 dilution) was increased the $IFN-{\gamma}$ and interleukin IL-4 production compared with media control (about l.4-fold for $IFN-{\gamma}$ and 1.6-fold for IL-4 P<0.05) at 48 h. Moutain grown ginseng (10-3 dilution) and moutain cultivated ginseng (10-4 dilution) were increased the turmor necrosis factor $TNF-{\alpha}$ production compared with $rIFN-{\gamma}$ treated cells (about 1.9-fold for $TNF-{\alpha}$ P<0.05), respectively. Moutain cultivated ginseng (10-3 dilution) was increased the IL-12 production compared with $rIFN-{\gamma}$ treated cell (about 1.7-fold for IL-12 P<0.05). Conclusion : These data suggest that three different three kinds of ginseng act on immune responses in different aspects.

• 대한바이러스학회지
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• 제27권2호
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• pp.209-216
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• 1997

Three dimensional structures of envelope protein from Korean isolates and Nakayama-NIH strain of Japanese encephalitis virus (JEV) were deduced by a computer program (HyperChem 4.0 Chemplus 1.0) based on the data of the three dimentional structure of Tick-borne encephalitis virus. In the three dimensional structure of envelope protein, neutralizing epitope and T-helper cell recognition site of C-terminal region of Korean isolates were structually similar to those of Nakayama-NIH but the N-terminal region was not. Korean JE isolates were compared with Nakayama-NIH strain by using cross-neutralization antibody test. Neutralizing activities of Korean isolates derived from guinea pigs were higher than those of Nakayama-NIH strain against Korean isolates, although the polyclonal antibody titers of Nakayama-NlH showed 1:160 to 1:640 against Korean isolates. According to the results from three dimentional structures and cross-neutralization analyses, the antigenic difference between Korean JE isolates and Nakayama-NIH strain may be dependent on structural difference of envelope protein.

• 한국콘텐츠학회논문지
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• 제7권12호
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• pp.83-94
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• 2007

포트폴리오는 구성주의 학습을 지원하는 한 방법으로 사용될 수 있다. 현재 교육 현장에서 포트폴리오의 사용이 점차 확대되고 있으나, 현장 적용의 실태나 발전적 활용 방안에 대한 연구는 미약한 편이다. 본 논문에서는 전국의 초 중등학교 재직 교사를 대상으로 포트폴리오 운영에 대한 실증적 자료를 분석하며, 이를 기반으로 지식정보화 사회에 필요한 e-포트폴리오의 설계 방향을 제안한다. 포트폴리오에 대한 이해도, 유형별 운영 현황 분석 결과에 따르면 학교급에 따른 차별화된 시스템 설계와 고경력자에 대한 연수 확대, '안내도우미' 기능 구비를 필요로 한다. 포트폴리오 작성을 위해 많은 시간을 소요하고 일회적, 형식적 수행 평가의 일환으로 운영되는 문제점을 개선하기 위해 학습과 평가를 하나의 과정에서 통합하는 시스템의 설계가 필요하다. 더불어 상호작용 및 자기 주도적 학습을 효과적으로 지원하는 e-포트폴리오의 설계가 요구된다.

• 유통과학연구
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• 제17권5호
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• pp.103-111
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• 2019

Purpose - This paper aims to examine a spirituality's impact on the posttraumatic interpersonal relationships of family violence with a structural equation model(SEM). This article starts with the research idea that family violence experience bring about negative emotion in terms of interpersonal relationship leading to the distribution of negative affect in social relationship. The research question of this study pinpoints on how family violence experience affects interpersonal relationship problems and how spirituality affects interpersonal relations problems. Based on the idea, we attempts to deal with spirituality's impact as a driving factor of transforming the distribution of negative affect. Research design, data, and methodology - The structural equation modelling(SEM) is employed as a analysis method of this study. SEM provides a chiefly cross-sectional statistical modelling method, and moreover it allows multiple variables to be associated with a latent variable in this analysis. 300 samples from Seoul, Gyeonggy and Gangwon are selected in the survey. We chose available 271 among them. Results - The results verify that trauma have placed an negative impact on personal relations. The study results also shows that the more serious get the degree of family violence trauma, the worse become interpersonal relationship problems. What is more interesting is that the degree of trauma's impact on interpersonal relation problems in male is higher than that of trauma's impact in female. It is mainly attributed to the fact that women are superior to men in terms of empathy ability and interpersonal relationship orientation. It can be noted that the well-managed spirituality will be able to make a great contribution towards reducing the degree of trauma caused by interpersonal relationships. Conclusions - The study results demonstrates that family violence have negative impacts on spirituality, while spirituality have an positive impacts on reduction the problems of interpersonal relationship. It has been found out that family violence trauma may cause negative affectivity in personal relations, which can distribute negative impacts regarding interpersonal relationship in society. This study also supports that spirituality will be able to function well as a helper, which may reduce the distribution of negative affect in society.

• Parasites, Hosts and Diseases
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• 제53권4호
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• pp.431-438
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• 2015

In Trichinella spiralis infection, type 2 helper T (Th2) cell-related and regulatory T ($T_{reg}$) cell-related immune responses are the most important immune events. In order to clarify which Toll-like receptors (TLRs) are closely associated with these responses, we analyzed the expression of mouse TLR genes in the small intestine and muscle tissue during T. spiralis infection. In addition, the expression of several chemokine- and cytokine-encoding genes, which are related to Th2 and $T_{reg}$ cell mediated immune responses, were analyzed in mouse embryonic fibroblasts (MEFs) isolated from myeloid differentiation factor 88 (MyD88)/TIR-associated proteins (TIRAP) and Toll receptor-associated activator of interferons (TRIF) adapter protein deficient and wild type (WT) mice. The results showed significantly increased TLR4 and TLR9 gene expression in the small intestine after 2 weeks of T. spiralis infection. In the muscle, TLR1, TLR2, TLR5, and TLR9 gene expression significantly increased after 4 weeks of infection. Only the expression of the TLR4 and TLR9 genes was significantly elevated in WT MEF cells after treatment with excretory-secretory (ES) proteins. Gene expression for Th2 chemokine genes were highly enhanced by ES proteins in WT MEF cells, while this elevation was slightly reduced in MyD88/$TIRAP^{-/-}$ MEF cells, and quite substantially decreased in $TRIF^{-/-}$ MEF cells. In contrast, IL-10 and $TGF-{\beta}$ expression levels were not elevated in MyD88/$TIRAP^{-/-}$ MEF cells. In conclusion, we suggest that TLR4 and TLR9 might be closely linked to Th2 cell and $T_{reg}$ cell mediated immune responses, although additional data are needed to convincingly prove this observation.