• Asian-Australasian Journal of Animal Sciences
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• 제15권1호
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• pp.61-65
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• 2002

The experiment was conducted to find out the effect of four feeding systems namely; stall feeding, tethering, restricted grazing and grazing on carcass characteristics of Black Bengal goat. Twenty four does of approximately 1 year of age were randomly selected for four treatments of feeding systems having 6 replications in each. Stall fed goats were kept into house all time and adequate amount of natural grass were supplied for ad libitum feeding. Goats of tethering group were tethered for eating natural grass from 8 a.m. to 4 p.m. and were transferred after one hour interval for changing the grazing place. Goats of restricted grazing group were allowed for grazing from 8 a.m. to 1 p.m. Goats of grazing group were grazed for 8 a.m. to 4 p.m. Concentrate supplement was given at the rate of 150 g per day per goat for all of the treatment groups. Goats were slaughtered after the experiment of 219 days. Body length and height at wither were significantly higher in stall feeding group than others. Average dressing percentage were 42.18, 39.0, 36.79 and 34.0 for stall feeding, tethering, restricted grazing and grazing groups, respectively. Dressing percentage varied significantly (p<0.05) among feeding groups. Caul fat and empty gut weight differed significantly (p<0.05) in all of the feeding systems but others non-carcass parameters did not differ significantly. Percentage of dry matter and ether extract were also significantly (p<0.05) higher in stall fed groups. In conclusion, among four treatment groups, performance of stall fed goats were most satisfactory and then tethering showed better performance than any other groups.

• Journal of Nutrition and Health
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• 제40권4호
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• pp.327-333
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• 2007

The present study was carried out to evaluate the physiological effects of mushroom supplementation on blood glucose levels, lipid profile, and antioxidant enzyme activities in subjects with type 2 diabetes mellitus. Subjects were randomized into either a control group or mushroom supplementation group. Mushroom supplementation was provided 3 times a day for 4 weeks. We found that total dietary fiber intake was about 2.5 times higher (30.3 g vs. 12.3 g) in subjects receiving mushroom supplementation than in the control group. Two groups maintained the same food intake and amount of activity, exercise during the supplementation. We observed no difference in age, height, weight, BMI (body mass index), blood pressure between the groups. Nutrient intake did not differ appreciably between the two groups, except for fiber intake, during the supplementation. Fasting blood glucose levels and 2-hour postprandial blood glucose levels were significantly lower in those ingesting mushroom than in controls. Furthermore, the concentrations of low-density lipoprotein cholesterol were decreased significantly in the mushroom supplementation group. Small changes were observed in the concentration of total cholesterol, triglyceride, high-density lipoprotein cholesterol of those supplemented with mushroom, but these changes were not statistically significant. Activities of superoxide dismutase and catalase with mushroom supplementation were higher than in controls, but and glutathione peroxidase activity was not affected. The levels of thiobarbituric acid reactive substance of mushroom group were lower than control group, but were not significant. We conclude that addition of mushroom influences glycemic control and may be effective in lowering blood lipids and improving antioxidant enzyme activities. Accordingly, such effects may reduce risk factors for cardiovascular disease in patients with type 2 diabetes. However, to confirm these effects and to make dietary recommendations for patients with type 2 diabetes, further studies are necessary.

• 한국식품위생안전성학회지
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• 제21권4호
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• pp.258-262
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• 2006

환경호르몬 물질의 생체내에서의 상호작용에 의한 상자 또는 상승 작용을 알아보기 위하여 환경호르몬 물질들을 조합하여 마우스에 처치한 후 생체내에서 생식기의 변화 정도를 조직병리학적으로 관찰하였다. 암컷 ICR마우스에 난소적출술을 실시하고 2주 후에 DEHP, DBP, BPA의 환경호르몬 물질을 단독 또는 두개씩 조합하여 마우스에 피하로 주입하였다. 육안적인 변화에서는 모든 군에서 이상이 관찰 되지 않았으며, 부검 후 자궁의 무게를 측정한 결과에 있어서도 유의적인 변화를 관찰할 수 없었으나, 자궁 내 fluid존재에 있어서는 E2 단독 투여 군과 E2와 함께 투여한 모든 그룹(E2+DEHP, E2+DBP, E2+BPA)에서 관찰되었다. 조직병리학적인 관찰에 있어서는.자궁상피세포, 질 상피세포, 유선의 변화 그리고 난관 직경의 변화를 관찰하였다. 그 결과 민감도에 있어서 가장 유의적인 변화를 보인 항목은 질 상피세포의 변화였으며, 환경호르몬 물질을 두개씩 혼합하여 처치한 그룹에 있어 단독으로 처치한 그룹과 비교 시 변화의 정도가 심한 것이 일부 관찰 되었으나 통계학적으로 유의성을 가지고 있다고 결론을 내리기 는 힘들었다. 결론적으로 환경호르몬물질간의 생체내에서 상가 혹은 상승작용에 대한 명확한 결과는 도출할 수 없었으나, 환경호르몬물질이 생체내 작용하는 데에 있어서 서로 간에 상승작용을 할 수 있다는 가능성은 충분한 것으로 판단되어진다.

• Journal of Korean Medical Science
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• 제33권50호
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• pp.320.1-320.8
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• 2018

Background: Muscle mass and muscle function are related to depressed mood in studies of adults. Like adults, Korean students are highly likely to suffer from decreased muscle mass due to social conditions. In this study, we evaluated the muscle mass status of Korean adolescents and assess the effect of muscle on depressive mood. Methods: A total of 1,233 adolescent boys and girls participants from the Korea National Health and Nutrition Examination Survey were enrolled in our study. Participants underwent dual-energy X-ray absorptiometry for assessment of appendicular muscle mass and completed questionnaires regarding depressed mood, stress, suicidal ideations, and attempts. Results: There was no difference in depressive mood according to muscle mass among boys (P = 0.634); girls with decreased muscle mass had a greater tendency for depressed mood compared to girls with optimal muscle mass (P = 0.023). After adjusting for age, waist circumference-to-height ratio, smoking status, alcohol consumption, frequency of physical activity, self-reported obesity, weight-loss efforts, and monthly household income, girls with low muscle mass (LMM) were 2.60 times more at risk of developing depression than girls with normal muscle mass (95% confidence interval [CI], 1.05-6.49; P = 0.040). This trend was similar for girls with LMM with obesity (95% CI, 1.00-11.97; P = 0.049). Conclusion: Adolescent girls who have insufficient muscle mass are more likely to report depressed mood than girls who have ideal muscle mass. Interventions for maintaining proper muscle mass are required.

• 대한한방부인과학회지
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• 제22권4호
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• pp.109-121
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• 2009

Purpose: The purpose of this study was to find out the correlation among body mass index (BMI), dysmenorrhea and digestion function. Methods: We conducted a questionnaire survey of 307 high school girls about their menstruation and digestion function from one high school located in Seoul from Mar. 23 to Mar. 28 in 2009. And the we measured their height and weight to calculate their BMI. Using one way ANOVA, chi-square test and pearson correlation, statistical analysis was made by SPSS 12.0. We significance level p-value was determined as 0.05. Results: 1. There was no significant correlation between BMI and the severity of dysmenorrhea. 2. There was no significant correlation between BMI and digestion power. 3. There was statistically mild correlation between dyspepsia and the severity of menstrual pains. Conclusion: From above results, we could conclude that dyspepsia had mild relation to menstrual pains.

• Asian-Australasian Journal of Animal Sciences
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• 제16권7호
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• pp.1035-1040
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• 2003

This experiment was conducted to investigate the effects of fat sources on growth performance, nutrient digestibility, serum traits and intestinal morphology in weaning pigs. A total of 128 weaning pigs (Landrace${\times}$Large White${\times}$Duroc, $21{\pm}2$ days of age, $5.82{\pm}0.13kg$ of average initial body weight) were allotted in a randomized complete block (RCB) design with four treatments: 1) corn oil, 2) soybean oil, 3) tallow and 4) fish oil. Each treatment had 8 replicates with 4 pigs per pen. During phase I period (d 0 to 14), pigs fed corn oil or soybean oil diet tended to show higher ADG and FCR than any other treatments although there was no significant difference. During phase II period (d 15 to 28), pigs fed corn oil diet showed better ADG and ADFI than pigs fed soybean oil, tallow or fish oil. For overall period, growth performance of weaning pigs was improved (p<0.05) when pigs were fed soybean oil or corn oil. Apparent digestibility of energy and fat was improved when pigs were fed corn oil diet (p<0.05). Supplementation of corn oil resulted in higher serum triglyceride concentration than the other treatments (p<0.05). However, there was a lower cholesterol concentration when corn oil was provided compared to tallow or fish oil. Pigs fed corn oil tended to have increased villus height compared with soybean oil, tallow or fish oil treatment (p<0.05). This experiment suggested that vegetable oils such as corn oil or soybean oil, were much better fat source for improving growth performance of weaning pigs.

• 대한인간공학회지
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• 제36권5호
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• pp.395-409
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• 2017

Objective: The purpose of this study was to optimize the number and positions of foot pressure sensors using the reliability analysis of the center of pressure (COP) in smart shoes. Background: Foot pressure can be different according to foot region, and it is important which region of the foot pressure needs to be measured. Method: Thirty adults (age: $20.5{\pm}1.8years$, body weight: $71.4{\pm}6.5kg$, height: $1.76{\pm}0.04m$) participated in this study. The foot pressure data were collected using the insole of Pedar-X system (Novel GmbH, USA) with a sampling frequency of 100Hz during 1.3m/s speed walking on the treadmill (Instrumented treadmill, Bertec, USA). The intraclass correlation coefficients (ICC) were calculated between the COP positions using 4, 5, 6, 7, 8, and 99 sensors, while one-way repeated measure ANOVA was performed between the standard deviation (SD) of the COP positions. Results: The medio-lateral (M/L) COP position using 99 sensors was positively correlated with the M/L COP positions using 6, 7, and 8 sensors; however, it was not correlated with the M/L COP positions using 4 and 5 sensors during landing phase (1~4%) (p<.05). The antero-posterior (A/P) COP position using 99 sensors was positively correlated with the A/P COP positions using 4, 5, 6, 7, and 8 sensors (p<.05). The SD of the COP position using 99 sensors was smaller than the SD of the M/L COP positions using 4, 5, 6, 7, and 8 sensors (p<.05). Conclusion: Based on our findings, it is desirable to arrange at least 6 sensors in smart shoes. Application: The study of optimizing the number and positions of foot pressure sensors would contribute to developing more effective smart shoes using foot pressure technology.

• 대한지역사회영양학회지
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• 제8권3호
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• pp.280-287
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• 2003

To investigate effects of the shared living on nutrient intakes,250 college male students who were living alone (104 men) or sharing accommodation with friends (134 men) were participated. Their average age was 22.6 years, their average height was 171.8 cm, their average weight was 65.6 kg and their average Body Mass Index (BMI) was 22.2. The caloric intakes of the men living alone or sharing accommodation were 55.9% and 72.5% of the Korean Recommended Dietary Allowance (RDA), respectively. The decreased caloric level of the group living alone seemed to be due to their decreased protein and fat consumption as compared to that of the group sharing accommodation. The group living alone consumed increased amounts of fiber for breakfast and half the carbohydrates, but more fat (p < 0.05) in snacks than the group sharing accommodation. The daily carbohydrate : protein : fat (C : P : F) ratio averaged 58.6 14.1 27.3, which is a lower carbohydrate and a higher fat ratio than the Korean recommended ratio. However, the group living alone was closer to the Korean recommended ratio than the group sharing accommodation. The food intake habits were evaluated as being poorer in the group living alone as compared to the group sharing accommodation, less frequent consumption of fried / pan-fried dishes, and fruits / juices, but more frequent consumption of instant / processed foods. In comparing the eating patterns of the two groups, the group living alone showed better eating habits, such as more“breakfast eating”and less“snacking in the morning, afternoon or late at night”whereas the group sharing accommodation showed better eating habits such as less“picky eaters”and less “eating out”. In the group living alone, their lower caloric intake was assumably due to their fewer side dishes, however they showed higher eating frequencies of instant i processed foods. Since the lifestyle of living alone seems to grow gradually among young men, we strongly recommend dietary education for them.

• 한국임상약학회지
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• 제28권1호
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• pp.24-29
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• 2018

Background: Cyclosporine is an immunosuppressive agent used to treat and prevent graft versus host reaction (GVHR)-a complication associated with stem cell transplantation. This study aimed to develop a population pharmacokinetic model of cyclosporine and investigate factors affecting cyclosporine clearance in pediatric hematopoietic stem cell transplant patients. Methods: A total of 650 cyclosporine concentrations recorded in 65 patients who underwent hematopoietic stem cell transplantation were used. Data including age, sex, weight, height, body surface area (BSA), type of disease, chemotherapy before stem cell transplantation, type of donor, serum creatinine levels, total bilirubin concentration, hematocrit value, and type of concomitant anti-fungal agents and methylprednisolone used were retrospectively collected. Data related to cyclosporine dosage, administration time, and blood concentration were also collected. All data were analyzed using the non-linear mixed effect model; a two-compartment model with first-order elimination was used. Results: The population pharmacokinetic model of cyclosporine using the NONMEM program was as follows: $CL(L/h)=5.9{\times}(BSA/1.2)^{0.9}$, V2 (L) = 54.5, Q (L/h) = 3.5, V3 (L) = 1080.0, $k_a(h^{-1})=0.000377$. BSA was selected as a covariate of cyclosporine clearance, which increased with an increase in BSA. Conclusion: A population pharmacokinetic model for Korean pediatric hematopoietic stem cell transplant patients was developed, and the important factor affecting cyclosporine clearance was found to be BSA. The model might contribute to the development of the most appropriate dosing regimen for cyclosporine. Further studies on population pharmacokinetics should be carried out, prospectively targeting pediatric patients.

• Asian-Australasian Journal of Animal Sciences
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• 제31권1호
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• pp.106-115
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• 2018

Objective: The goal of this study was to investigate the effects of dietary standard ileal digestible (SID) valine:lysine ratios on performance, intestinal morphology, amino acids of liver and muscle, plasma indices and mRNA expression of branched-chain amino acid (BCAA) metabolism enzymes. Methods: A total of 144 crossbred pigs (Duroc${\times}$Landrace${\times}$Large White) weaned at $28{\pm}4days$ of age ($8.79{\pm}0.02kg$ body weight) were randomly allotted to 1 of 4 diets formulated to provide SID valine:lysine ratios of 50%, 60%, 70%, or 80%. Each diet was fed to 6 pens of pigs with 6 pigs per pen (3 gilts and 3 barrows) for 28 days. Results: Average daily gain increased quadratically (p<0.05), the villous height of the duodenum, jejunum and ileum increased linearly (p<0.05) as the SID valine:lysine ratio increased. The concentrations of plasma ${\alpha}-keto$ isovaleric and valine increased linearly (p<0.05), plasma aspartate, asparagine and cysteine decreased (p<0.05) as the SID valine:lysine ratio increased. An increase in SID lysine:valine levels increased mRNA expression levels of mitochondrial BCAA transaminase and branched-chain ${\alpha}-keto$ acid dehydrogenase in the longissimus dorsi muscle (p<0.05). Conclusion: Using a quadratic model, a SID valine:lysine ratio of 68% was shown to maximize the growth of weaned pigs which is slightly higher than the level recommended by the National Research Council.