• The Journal of Pediatrics of Korean Medicine
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• v.29 no.2
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• pp.59-77
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• 2015

Objectives Medical plant has a big role in Herbal Medicines, and most medical plant has phytoestrogens. Therefore some estrogenic effects have been reported in a lot of Korean Medicine literature. Phytoestrogens should be used carefully in children. The objective of this study is to identify reported phytoestrogenic effects in Herbal Medicines and to evaluate the characteristics of the phytoestrogens in Herbal Medicines. Methods A literature search was done with using 8 databases with a limit of reports until 12/31/2013. The estrogenic effects were summarized by each individual Korean Medicine. The frequency of the phytoestrogens was also investigated depending on the Korean medical categorization by the treatment effect. Results and Conclusions Phytoestrogenic effects were reported in 89 Herbal Medicines. Phytoestrogens were act bidirectionally, and the effect was fairly weak compared to estrogen. Phytoestrogenic effect was variable on different cells and tissues. The most frequent phytoestrogenic effect was in tonifying and replenishing medicinal, the following orders were heat-clearing, exterior-releasing, and blood-activating and stasis-dispelling medicinal. Phytoestrogens were not reported in dampness-resolving, digestant, orifice-opening, emetic medicinal.

• Journal of Haehwa Medicine
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• v.10 no.2
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• pp.31-40
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• 2002

According to the literatural study on the utility of TaeWonEum, the results were as follows 1. TaeWonEum is the prescription originally registered on Zang jie Bin's ${\ll}$Jing-Yue-Quan-Shu${\gg}$ and because of the dificiency of the renmai, the chongmai in women, it is made for the discomfort of the pregnancy 2. On the treatment of miccarriage, they were used to the methods of tonificating qi and blood, tonificating insufficiency, making flesh, eliminating wind, tonificating the spleen, clearing heat, eliminating stagnant blood, tonificating blood, growing zhang qi, etc but it is almostly used to the method of tonificating qi and blood 3. TaeWonEum is used on the purposes of tonificating the spleen and stomach, qi and blood, on the case of both the discomfort of the pregnancy by the dificiency of the renmai, the chongmai in women, and the insufficiency of fetal growth by the difficiency of the spleen and stomach, qi and blood 4. The symptoms can be used which are the fetal problem of incipient pregnancy, quickening, lumbago, distension, pallor, weakness of the mind, dizziness, cold, anorexia 5. The additional methods of TaeWonEum are as follows when much turbid enuresis is concerned, Disscoreae Rhizoma, Psoraleae Fructus, Schizandrae Fructus can be added when a patient is very difficient of qi, Atractylodis Macrocephalae Rhizoma is doubled and Astragali Radix can be added when a patient is often vomiting with asthenia-cold, Typhae Pollen can be added when a patient has fever and weak, Scutellariae Radix or Rehmanniae Radix can be added and E ucommiae Cortex can be subtracted when a patient has the colicky pain because of the difficiency of yin, Lycii Fructus can be added when a patient is at a great rage and qi is ascenting, Cyperi Rhizoma or Amomi Fructus can be added when a patient has hemorrage with trauma, Dipsaci Radix, Asini Gelatinum can be added when a patient's vomiting can not be reduced, Pinelliae Rhizoma, Zingiberis Rhizoma Recens can be added

• The Korea Journal of Herbology
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• v.23 no.3
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• pp.33-40
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• 2008

Objectives : For the purpose of developing Korean herbalogy of the plants belonging to Pteridaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article. Methods : The examined herbalogical books and research papers which published at home and abroad. Results : 1: There are totaled to 12 genera and 33 species in Pteridaceae in Korea and among them medicinal plants are 10 genera, 19 species, some 58% in total. 2: Adiantum genus is main kind enough that it has 5 species among 33 species in Pteridaceae, of which medicinal plants are 4 species. 3: The herb is the main medicinal parts if medicinal plants in the Pteridaceae, which is used in 18 species. 4: According to nature and flavor of medicinal plants in the Pteridaceae, they were classified into cold 15 species, and cool 11; bitter taste 12, little bitter taste 11 and sweet taste 5 in the order. 5: According to meridian propism of medicinal plants in the Pteridaceae, they were classified into liver meridian 15 species, lung and large intestine meridian 8 species, heart meridian 6 species. 6: According to the properties and principal curative action, they were classified into drugs for clearing away heat 24 species, drugs for detoxification 22 species, drugs for promoting diuresis 12 species in the order. 7: The number of toxic species in the Pteridaceae was examined to be 2 species. Conclusions : There are totaled to 12 genera and 33 species in Pteridaceae in Korea and among them medicinal plants are 10 genera, 19 species, some 58% in total.

• Journal of the Korean earth science society
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• v.39 no.5
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• pp.403-418
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• 2018

This study conducted synoptic and mesoscale analyses to understand the cause of Japan Tsukuba tornado development, which occurred at 0340 UTC 6 May 2012. Prior to the tornado occurrence, there was a circular jet stream over Japan, and the surface was moist due to overnight precipitation. The circular jet stream brought cold and dry air to the upper-level atmosphere which let strong solar radiation heat the ground with clearing of sky cover. A tornadic supercell developed in the area of potentially unstable atmosphere. Sounding data at Tateno showed a capping inversion at 900 hPa at 0000 UTC 6 May. Strong insolation in early morning hours and removal of the inversion instigated vigorous updraft with rotation due to vertical shear in the upper-level atmosphere. This caused multiple tornadoes to occur from 0220 to 0340 UTC 6 May 2012. When comparing Tateno's climatological temperature and dew-point temperature profile on the day of event, the mid-level atmosphere was moister than typical sounding in the region. This study showed that tornado development in Tsukuba was caused by a combination of (a) topography and potential vorticity anomaly, which increased vorticity over the Kanto Plain; (b) vertical shear, which produced horizontal vortex line; and c) thermal instability, which triggered supercell and tilted the vortex line in the vertical.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.2
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• pp.202-211
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• 2011

The stems and branchs of Euryale ferox Salisbury (EF), are used in Chinese herbal medicine for latent-heat-clearing, antipyretic, detoxicant and anti-inflammatory ailments. This plant is used worldwide for the treatment of many types of inflammatory disease including respiratory infections, diabetes mellitus, rheumatoid arthritis and play an important role in the immune reaction. Topical natural antioxidants are a useful strategy for the prevention of oxidative stress mediated inflammatory disease. Plants produce significant amounts of antioxidants to prevent the oxidative stress caused by photons and oxygen, therefore they represent a potential source of new compounds with antioxidant activity. This study was designed to evaluate whether EFEA (ethylacetate fraction of EF) may ameliorate oxidative stress and inflammatory status through the antioxidative mechanism in LPS-stimulated RAW 264.7 murine macrophage cell line. Treatment of RAW 264.7 cells with EFEA significantly reduced LPS-stimulated inflammatory response in a dose-dependent manner. In conclusion, the EF extracts have anti-inflammatory effects in vitro system, which can be used for developing pharmaceutical drug against oxidative stress and chronic inflammatory disease.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.4
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• pp.101-115
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• 2019

Objectives : The purpose of this study is to analyze the use of herbal medicine as a treatment method in the case studies on warts in Korea, to identify trends in herbal medicines and herbal prescriptions according to the characteristics of individual patients and to systematically analyze concurrent therapies. Methods : Domestic databases (OASIS, RISS, NDSL, KTKP, KISS, KISTI, KISTI) were used to search for case studies related to the herbal medicine treatment of warts. There was no restriction on the time of publication. A total of 9 papers were selected. Results : A total of 13 prescriptions were presented 23 times in 18 cases. Among them, bojungikgi-tang gamibang(補中益氣湯加減方) was the most frequently prescribed. Gwakhyangjeonggi-san gamibang(藿香正氣散加減方) and Damsoeun-tang gagam were the next most frequently prescribed. 69 herbs were used in a total of 13 prescriptions. Herbs were commonly classified as heat-clearing medicine(淸熱藥), exterior-releasing medicine(解表藥), and tonifying and replenishing medicine(補益藥) in descending order. The herbs used more than 6 times included Coicis Semen(薏苡仁), Glycyrrhizae Radix et Rhizoma(甘草) (10 times), Bupleuri Radix(柴胡), and Scutellariae Radix(黃芩) (6 times). Concurrent therapies were performed except for 1 study, and they were acupuncture, moxibustion, pharmacopuncture, external agents, and cupping therapy. Conclusions : This is the first study to analyze the use of herbal medicine as a treatment method for warts in case studies performed in Korea. We hope that this study would give helpful information about the treatment of warts in clinical practices.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.1
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• pp.1-12
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• 2015

Objectives: Taraxaci Herba (TH) have been used in oriental medicine for many centuries as a heat-clearing, detoxifying and stimulating milk secretion drug. Therefore, the purpose of this study was to investigate the effects of TH on the sex hormone changes and lipid metabolism in the experimental model. Methods: The experimental model of menopause was induced by bilateral ovariectomy in rats. We used TH extract with freeze-dried and $200{\pm}20g$ female Sprague-dawley rats for this Study. The level of serum total cholesterol, serum triglyceride, serum HDL-cholesterol, serum total estrogen, serum progesterone, serum follicle stimulating hormone (FSH), and body weight were measured. Results: The results of this study were obtained as follows; 1. Sample A and Sample B significantly decreased body weight and level of serum total cholesterol, and significantly increased level of serum total estrogen as compared with control group. 2. Sample A decreased level of serum triglyceride, and was increased level of HDL-cholesterol, serum progesterone, serum FSH as compared with control group. 3. Sample B significantly increased level of HDL-cholesterol, serum FSH as compared with control group. 4. Sample B decreased level of serum triglyceride, and was increased level of serum progesterone as compared with control group. Conclusions: These results suggest that TH could be applied effectively on the treatment of menopausal syndrome.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.3
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• pp.66-94
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• 2022

Objectives : Diabetic Foot Ulcer(DFU) is one of the common complications of diabetes. DFU is difficult to treat compared to other chronic wounds and clinically effective treatments are limited. The purpose of this study is to review the of external ointment treatment for DFU. Methods : 8 databases such as PubMed, EMBASE, CENTRAL, CNKI, NDSL, RISS, KISS, OASIS including English, Korean and Chinese were searched by structured search strategies that consist of terms as 'diabetic foot', 'diabetic foot ulcer(DFU)' and 'randomized' from January 2001 to January 2021. All randomized controlled trials(RCTs) involving treatment group as external ointment or in combination with conventional treatment were included. Results: A total of 20 RCTs was identified and analyzed. In treatment group, ointment was applied based on conventional treatment. A total of 16 different ointments were used, and the frequency of use was highest in the order of Heat-clearing drug, Blood-activating and stasis-dispelling drug, Tonifying and Replenishing drug and Orifice-opening drug. The most used herbs were in the order of Coptis chinensis Franch., Phellodendron chinense Schneid., Borneolum syntheticum., Angelica sinensis(Oliv.) Diels. In treatment group, a clinically effective effect was obtained compared to the contrast group. Conclusions : The result of this study suggest that external ointment treatment based on conventional treatment can be applied to DFU.

• The Journal of Internal Korean Medicine
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• v.18 no.2
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• pp.268-295
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• 1997

Sweating is natural phenomenon necessary for the regulation of an individual's body-temperature. The secretion of sweat is mediated by a portion of our vegetative nervous system(the sympathetic nervous system). In some people, this system is working at a very high activity level, far higher than needed to keep a constant temperature. This condition is referred to as hyperhidrosis. Especially excessive sweating of the hands and the feet is palmoplantar hyperhidrosis or volar hyperhidrosis. This is by far the most distressing condition. It was founded that the first important cause of this was emotional factor. The hands are much more exposed in social and prefessional activities than any other part of our body. Many individuals with palmoplantar hyperhidrosis are limited in their choice of proffession, because unable to manipulate materials sensitive to humidity or reluctant to shake hands; some patients arrive to the point to avoid social contact. The occidental medical treatments for palmoplantar hyperhidrosis include application of topical agents(chemical antiperspirants such as aluminum chloride), iontophoresis(treatment with electrical current), or surgery(thoracic sympathectomy). It was reported that the most effective treatment was thoracic sympathectomy. So this study was started to find the easy and effective oriental medical treatments against the occidental medical treatments through the oriental medical literature. The occidental medical idea for palmoplantar hyperhidrosis is only limited in neurologic system, so surgery is the best treatment. But the oriental medical idea for palmoplantar hyperhidrosis is much wider, so the oriental medical causes and treatments for this are able to be veriety. And the oriental medical teatment is freely in treating the patients of palmoplantar hyperhidrosis, because entire idea including pulse, facial color, mental condition, constitution and other symptom exists in the oriental medicine. The results of a bibliographic study of causes and treatments for palmoplantar are as follows; 1. The main causes of pa1moplantar hyperhidrosis are heat in the stomach, damp-heat in the spleen and the stomach, insufficiency of the spleen-qi and the stomach-qi, deficiency of the spleen-yin and the stomach-yin, and the others are the stomach-cold syndrome, stasis of blood and dyspepsia in the stomach, disorder of the liver-qi, deficiency of the heart-yin and the kidney-yin, deficiency of the heart-yang and the kidney-yang, stagnated heat in the liver and the spleen, the lung channel-heat etc. 2. The main methods of medical treatments for palmoplantar hyperhidrosis are clearing out the stomach-heat, eliminating dampness and heat in the spleen and the stomach, invigorating the spleen-qi and the stomach-qi, reinforcing the spleen-yin and the stomach-yin, warming the stomach, relaxing the liver and alleviating of mental depression and tonifying the heart and the kidney etc. 3. The main prescriptions of palmoplantar hyperhidrosis are Taesihotang, Palmultang-kakam, Samyeongbaechusan, Chongbisan, Sasammaekmundongtang, the others are Leejungtang, Hwangkikonjungtang, Seungkitang, Boyumtang, Baekhotang, Chongsimyonjayum, Moyrosan, etc. 4. Local medicine for external use are liquid after boiling alum in water for about 1 or 2 hours, liquid after boiling alum and pueraria root in water and liquid after boiling stragalus root, pueraria root, ledebouriella root and schizonepeta in water, etc. 5. The methods of acupuncture therapy include invigorating Bokyru, Yumkuk and purgating Hapkouk, or invigorating Bokyru, Kihae and purgating Hapkouk, or steadying Hapkouk, Nokung.

• The Journal of Internal Korean Medicine
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• v.19 no.2
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• pp.438-450
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• 1998

Pleural effusion means the inflammation of pleura which has a majority of respiratory disease. The main clinical manifestation is pleural effusional pain, dyspnea, cough, fever, etc. and at present the Tuberculous pleural effusion has the most frequency in which exists exudate in our country. And during studying oriental medical treatment about Tuberculous exudative pleural effusional patient, we found the clinical case about The Combination therapy of Chinese traditional and Western medicine at journal of traditional Chinese Medicine and considered it would be help in oriental medical treatment, so we adjust and report now. This study was performed by analyzing the six papers reported centering around the clinical case of The Combination therapy of Chinese traditional and Western medicine in journal of traditional Chinese Medicine published between 1990-1996. As these papers have no mistakes on diagnosis because it obtained pleurocentesis, tuberculin test positive reaction on choicing clinical case, definite results on X-ray, ultrasound as well as clinical basis, so it considers an apt conclusion. The results were as follows: 1. Western medical treatment uses chemical remedy same with pulmonary tuberculosis, and in case of tubercular pleuritis, it needs thoracic duct pyorrhea, and according to simple exudation also operates therapheutic pleural paracentesis. 2. In case of hydrothorax absorption about tuberculous pleural effusion, prescription of purge the heat accumulated in the lung and eliminate the retention of fluid with powerful purgatives shows considerable effects. 3. The latter period treatment of tuberculous pleural effusion needs Supplement qi and active the collaterals, Nourishing yin and clearing heat in addition to Supporting healthy energy to eliminate evils. 4. In case of curing tuberculous pleural effusion, The Combination therapy of Chinese traditional and Western medicine shows more considerable effect than single western medical treatment in absorption of hydrothorax. 5. In case of curing tuberculous pleural effusion, The Combination therapy of Chinese traditional and Western medicine shows more considerable effect than single western medical treatment in prevention of disease reappearance. 6. In case of curing tuberculous pleural effusion, The Combination therapy of Chinese traditional and Western medicine shows more considerable effect than single western medical treatment in vitality recovery at the latter period of disease.