• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2004년도 유체기계 연구개발 발표회 논문집
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• pp.225-231
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• 2004

Scroll compressor has been used extensively for refrigeration since the early 1980's for its improved efficiency, greater reliability, smoother operation, lower noise and vibration. And also, nowadays, the scroll mechanism is used for expander even though in niche market yet. But scroll expander has not been used for high-temperature and high-pressure gas, because the continuous expansion of the gas causes a wide range of temperature distribution over the whole scroll wrap that leads to differential thermal expansion of scroll elements, which results in system vibrations, noise and efficiency losses. For the scroll expander to produce power more efficiently, all of radial and radial clearances between scroll wrap must be the same. In order to reduce differential thermal expansion in addition to improvements in thermal efficiency and specific power, we propose a scroll expander with heating structure. Heat-pipe heating structure is considered as the most effective method to heat the scroll expander at a uniform temperature. This paper includes some results of preliminary study of the scroll expander with heating structure and proposals of their systems for power generation and refrigeration.

• 설비공학논문집
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• 제14권11호
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• pp.914-922
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• 2002

Thermo-acoustic waves can be thermally generated in a compressible flow field by rapid heating and cooling, and chemical reaction near the boundary walls. This mechanism is very important in the space environment in which natural convection does not exist. Also this may be a significant factor for heat transfer when the fluids are close to the thermodynamic critical point. In this study, the generation and transmission characteristics of thermo-acoustic waves in an air-filled confined domain with two-step pulsed heating are studied numerically. The governing equations are discretized using control volume method, and are solved using PISO algorithm and second-order upwind scheme. For the purpose of stable solution, time step was set to the order of $1\times10_-9s,\;and\;grids\;are\;50\times2000$. Results show that temperature and pressure distributions of fluid near the boundary wall subjected to a rapid heating are increased abruptly, and the induced thermo-acoustic wave propagates through the fluid until it decays due to viscous and heat dissipation. Pressure waves have sharp front shape and decay with a long tail in the case of step heating, but these waves have sharp pin shape in the case of pulsed heating.

• Journal of Microbiology and Biotechnology
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• 제34권7호
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• pp.1491-1500
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• 2024

Inflammation is a biodefense mechanism that provides protection against painful conditions such as inflammatory bowel disease, other gastrointestinal problems, and irritable bowel syndrome. Paraprobiotics have probiotic characteristics of intestinal modulation along with merits of safety and stability. In this study, heat-killed Lactiplantibacillus plantarum KU15122 (KU15122) was investigated for its anti-inflammatory properties. KU15122 was subjected to heat-killed treatment for enhancement of its safety, and its concentration was set at 8 log CFU/mL for conducting different experiments. Nitric oxide production was most remarkably reduced in the KU15122 group, whereas it was increased in the LPS-treated group. In RAW 264.7 cells, KU15122 inhibited the expression of inducible nitric oxide synthase, cyclooxygenase-2, interleukin (IL)-1β, IL-6, and tumor necrosis factor-α. ELISA revealed that among the tested strains, KU15122 exhibited the most significant reduction in PGE2, IL-1β, and IL-6. Moreover, KU15122 inhibited various factors involved in the nuclear factor-kappa B, activator protein-1, and mitogen-activated protein kinase pathways. In addition, KU15122 reduced the generation of reactive oxygen species. The anti-inflammatory effect of KU15122 was likely attributable to the bacterial exopolysaccharides. Conclusively, KU15122 exhibits anti-inflammatory potential against inflammatory diseases.

• 에너지공학
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• 제23권1호
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• pp.7-20
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• 2014

본 연구에서는 전국적으로 48만ha에 걸쳐 연료림으로 조성되어 있는 리기다소나무를 에너지연료로 활용하기 위해 최적의 생산시스템을 개발하고 이에 따른 공급가격과 전기 열 판매가격 및 이용률 등을 고려한 우드칩 연료한계가격을 산출하였으며 다양한 시나리오에 따른 경제성 민감도 분석을 수행하였다. 열 및 발전 전용시설에서의 경제성을 결정짓는 가장 중요한 변수는 연료공급가격이다. 열 전용시설에서는 본 연구에서 제안된 모든 생산시스템에서 생산되는 우드칩 연료의 활용이 가능하며 발전 전용시설에서는 생산비가 가장 높은 연료사용에는 일부 한계가 있으나 전기 판매가격이 현재의 SMP(pitch pine : 계통한계가격)보다 높아지거나 이용률이 80%이상으로 되는 경우 모두 활용 가능한 것으로 분석되었으며, 더욱이 RPS제도 시행에 따른 신재생에너지 인증서(REC:Renewable Energy Certificate)편익과 온실가스 절감효과로 CDM(Clean Development Mechanism)편익 등을 고려할 경우 충분히 활용 가능한 것으로 분석되었다. 따라서, 국내 발전부문에서의 RPS 공급의무율 이행을 위해서 산림 바이오매스의 활용이 적극 권장된다.

• 동의생리병리학회지
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• 제30권4호
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• pp.266-273
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• 2016

Ohmae-hwan has been used to treat the symptoms of loose stools mixed with blood accompanied by abdominal pain due to heat dysentery in Korean medicine. However, its mechanism of action on inflammatory disease using macrophages was not known. The author was to find out about the influence of Ohmae-hwan water extract on expressions of NO, cytokine IL-6 and TNF-α in LPS-stimulated RAW 264.7 cell, on expressions of mRNA of iNOS, IL-6 and COX-2 and on suppression of expressions of protein of iNOS and COX-2, and was to find out about the mechanism. As a result of the study, it was found that Ohmae-hwan suppressed generation of NO activated by LPS depending on its concentrations, suppressed expressions of cytokine IL-6, and TNF-α and suppressed expressions of mRNA of iNOS, IL-6, and COX-2 and suppressed expressions of protein of iNOS, COX-2. Considering the above results, it can be known that Ohmae-hwan water extract has anti-inflammatory effect against inflammatory response mediated by macrophages by suppressing generation of NO, TNF-α, and IL-6 and expressions of iNOS, COX-2 as it acts on macrophages.

• The Korean Journal of Physiology and Pharmacology
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• 제1권2호
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• pp.209-219
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• 1997

Previous studies have demonstrated that oxidative stress involving generation of reactive oxygen species (ROS) is responsible for the cytotoxic action of $TNF{\alpha}$. Protective effect of small heat shock proteins (small HSP) against diverse oxidative stress conditions has been suggeted. Although overexpression of small hsp was shown to provide an enhanced survival of $TNF{\alpha}$-sensitive cells when challenged with $TNF{\alpha}$, neither the nature of $TNF{\alpha}$-induced cytotoxicity nor the protective mechanism of small HSP has not been completely understood. In this study, we have attempted to determine whether $TNF{\alpha}$ induces oxidative DNA damage in $TNF{\alpha}$-sensitive L929 cells. We chose to measure the level of 8-hydroxy-2'-deoxyguanosine (8 ohdG), which has been increasingly recognized as one of the most sensitive markers of oxidative DNA damage. Our results clearly demonstrated that the level of 8 ohdG increased in L929 cells in a $TNF{\alpha}$ dose-dependent manner. Subsequently, we asked whether small HSP has a protective effect on $TNF{\alpha}$-induced oxidative DNA damage. To accomplish this goal, we have stably transfected L929 cells with mouse small hsp cDNA (hsp25) since these cells are devoid of endogenous small hsps. We found that $TNF{\alpha}$-induced 8 ohdG was decreased in cells overexpressing exogenous small hsp. We also found that the cell killing activity of $TNF{\alpha}$ was decreased in these cells as measured by clonogenic survival. Taken together, results from the current study show that cytotoxic mechanism of $TNF{\alpha}$ involves oxidative damage of DNA and that overexpression of the small hsp reduces this oxidative damage. We suggest that the reduction of oxidative DNA damage is one of the most important protective mechanisms of small HSP against $TNF{\alpha}$.

• 조명전기설비학회논문지
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• 제22권9호
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• pp.103-110
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• 2008

전기안전 측면에서 전기설비의 환경영향을 평가하고 국내규정에 맞도록 개선하기 위한 검토가 필요하다. 본 논문은 분진발생지역에서 현장실측과 분석을 통해 위험성을 평가하였다. 분진은 절연재료 표면에 부착되어 사고의 원인이 된다. 분진에 의한 전기사고의 메커니즘에 있어서 분진이 전기설비에 쌓이던, 누설전류가 흐르고, 표면이 탄화된다. 이후 줄열에 의해 전기화재가 발생한다. 실태조사결과, 보호 장치 또는 분전함에서 분진이 발견되었으며, 포집된 분진은 포집량과 도전율이 각각 달랐다. ICP-AES에 있어서 대체로 나트륨성분이 검출되었고 고무재생공장의 경우에는 아연과 칼슘성분이 검출되었다. 하수처리장에서는 나트륨, 마그네슘, 철, 칼슘, 알루미늄 등의 성분이 검출되었다. 따라서, 현장실측과 분진의 분석은 분진발생지역에서의 전기적 위험성 평가의 중요한 자료가 될 것이다.

• Korean Chemical Engineering Research
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• 제50권5호
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• pp.850-859
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• 2012

목질계 바이오매스의 가스화 및 열분해 공정에서 탈휘발 과정은 매우 중요한 메커니즘 중의 하나이며, 공정 설계 시 반드시 반영되어야 한다. 바이오매스 입자의 탈휘발에 대한 많은 경험식이 존재하지만, 다양한 특성의 바이오매스를 특정 실험조건에서 도출한 경험식에 의존하기는 힘들다. 본 연구는 유동층 가스화 분위기에서의 바이오매스 단일 입자의 탈휘발 과정을 수학적 모델을 통하여 예측하였다. 모델은 다양한 형태의 입자를 구형태로 변환한 뒤, 입자 내부의 drying, shrinkage, heat generation을 고려하여 1차원으로 해석하였다. 또한 탈휘발 과정에 영향을 주는 입자의 크기, 반응온도, 초기 수분함량, 열전달 계수, 반응모델 등 다양한 변수에 대한 변화를 관찰하였다. 탈휘발 완료시간은 입자의 크기가 커질수록, 초기 수분함량이 높을수록 증가하였으며, 반응온도가 높을수록 선형적으로 감소하였다. 또한 외부 열전달 계수가 300 $W/m^2K$ 이상일 경우 큰 변화는 나타나지 않았지만, 입자의 크기가 작을수록 외부 열전달 계수의 영향은 크게 나타났다. 모델 예측값과 문헌의 실험값은 대체로 비슷한 경향을 나타내었으며, 오차 ${\pm}10%$ 이내로 근접하였다.

• Journal of the Korean Wood Science and Technology
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• 제42권3호
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• pp.339-345
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• 2014

집성재의 생산성 향상을 위한 고주파 가열 경화기술에 대해 연구하였다. 고주파가 유전체에 가해지면 내부에서 에너지 손실에 의한 발열이 발생한다. 집성재를 구성하는 라미나와 접착제는 유전체이므로 집성재에 고주파를 주사하면 내부에서 발열이 발생한다. 집성재 제조에 이용되는 대부분의 상온 경화형 접착제는 고온에서 빠른 경화가 이루어지므로 고주파 가열 기술을 이용하면 집성재 내부 접착층의 온도를 상승시킴으로써 빠른 경화를 유도할 수 있다. 본 연구에서는 낙엽송재와 phenol-resorcinol-formaldehyde (PRF) 접착제의 유전 특성을 평가하고, 집성재 내부의 접착층의 빠른 경화를 유도하는 고주파 가열 경화 기작을 이론적으로 분석하였다. 연구 결과, 온도상승인자인 PRF 접착제의 상대손실계수가 낙엽송재의 상대손실계수에 비해 높았으나, 온도상승저해인자인 밀도와 비열도 높았다. 그러나 상대손실계수의 비율이 온도상승저해인자의 비율보다 높기 때문에 고주파 가열에 의한 발열량은 접착제에서 더 높을 것으로 예상된다. 이러한 실험 결과를 이용한 이론적 접근을 바탕으로, 접착층이 목표온도까지 상승하기 위한 ISM 영역의 고주파 주파수 별 전기장의 상대 세기를 추정하였다.

• 한국연소학회지
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• 제23권1호
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• pp.28-35
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• 2018

Entropy waves(or hot spots) in a gas turbine combustor are generated by irregular heat release from flames, then can be coupled with acoustic waves when they are accelerated at the exit of the combustor. This coupling mechanism between the entropy and the acoustic waves is generally known to be one of the triggers for combustion instability, which is commonly called "indirect" combustion noise. This paper reviews the fundamental theories on generation, propagation, and coupling with acoustic field of entropy waves and recent research results on the indirect combustion noise for gas turbine combustors.