• Journal of Korean Neurosurgical Society
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• v.60 no.5
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• pp.527-533
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• 2017

Objective : To investigate the efficacy of adjuvant treatment in patients with high-grade meningioma. Methods : A retrospective analysis was performed for patients with high-grade meningioma, World Health Organization grade 2 or 3, in a single center between 2003 and 2014. The patients were reviewed according to age at diagnosis, sex, the location of meningioma, degree of tumor resection, histological features, and type of adjuvant treatment. These factors were analyzed by Firth logistic regression analyses. Results : Fifty-three patients with high-grade meningioma were enrolled. Thirty-four patients received adjuvant treatment; conventional radiotherapy or radiosurgery. Clinical follow-up ranged from 13-113 months with a median follow-up of 35.5 months. Gross total removal (GTR), Simpson grade 1 or 2, was achieved in 29 patients and, among them, 13 patients received adjuvant treatment. In the other 24 patients with non-GTR, conventional adjuvant radiotherapy and radiosurgery were performed in 11 and 10 patients, respectively. The other 3 patients did not receive any adjuvant treatment. Radiation-related complications did not occur. Of the 53 patients, 19 patients had suffered from recurrence. The recurrence rate in the adjuvant treatment group was 23.5% (8 out of 34). On the other hand, the rate for the non-adjuvant treatment group was 57.9% (11 out of 19) (odds ratio [OR]=0.208, p=0.017). In the GTR group, the recurrence rate was 7.5% (1 out of 13) for patients with adjuvant treatment and 50% (8 out of 16) for patients without adjuvant treatment (OR=0.121, p=0.04). Conclusion : Adjuvant treatment appears to be safe and effective, and could lead to a lower recurrence rate in high-grade meningioma, regardless of the extent of removal. Our results might be used as a reference for making decisions when planning adjuvant treatments for patients with high-grade meningioma after surgery.

• Journal of Nutrition and Health
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• v.46 no.5
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• pp.410-417
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• 2013

Caloric restriction is recognized as one of the best treatment options for obesity, and is associated with changes in body composition. The purpose of this study was to determine the influence of age in caloric restriction in overweight and obese women. In this caloric restriction study, nutrient intake of 61 women was evaluated using food records written by subjects for three days. Body composition and metabolic risk factors were assessed before and after caloric restriction. Blood levels of lipids, glucose, leptin, and adiponectin were measured. Visceral fat and subcutaneous fat were evaluated using bioimpedance analysis. General linear models (GLM) identified the independent effects of age after co-varying baseline weight and difference of energy intake. Weight, fat mass, visceral fat, subcutaneous fat, and blood pressure showed a significant decrease by caloric restriction of 452 kcal/day. The percent changes in weight, visceral fat, and subcutaneous fat were -4.5%, -12.0%, and -8.2%, respectively, after caloric restriction. The percent changes of weight, visceral fat, and subcutaneous fat showed an independent association with age co-varying baseline weight and difference of energy intake. Decreased change in percent of leptin by caloric restriction also showed an association with age. Changes in body composition and leptin by caloric restriction showed an independent association with age. This may indicate greater difficulty in achievement of change of body composition as well as greater obesity-related metabolic risk with aging. Therefore, caloric restriction considering age should be recommended for effective dietary treatment in overweight or obese women.

• Kidney Research and Clinical Practice
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• v.36 no.1
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• pp.48-57
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• 2017

Background: Hepatic steatosis measured with controlled attenuation parameter (CAP) using transient elastography predicts metabolic syndrome in the general population. We investigated whether CAP predicted metabolic syndrome in chronic kidney disease patients. Methods: CAP was measured with transient elastography in 465 predialysis chronic kidney disease patients (mean age, 57.5 years). Results: The median CAP value was 239 (202-274) dB/m. In 195 (41.9%) patients with metabolic syndrome, diabetes mellitus was more prevalent (105 [53.8%] vs. 71 [26.3%], P < 0.001), with significantly increased urine albumin-to-creatinine ratio (184 [38-706] vs. 56 [16-408] mg/g Cr, P = 0.003), high sensitivity C-reactive protein levels (5.4 [1.4-28.2] vs. 1.7 [0.6-9.9] mg/L, P < 0.001), and CAP (248 [210-302] vs. 226 [196-259] dB/m, P < 0.001). In multiple linear regression analysis, CAP was independently related to body mass index (${\beta}=0.742$, P < 0.001), triglyceride levels (${\beta}=2.034$, P < 0.001), estimated glomerular filtration rate (${\beta}=0.316$, P = 0.001), serum albumin (${\beta}=1.386$, P < 0.001), alanine aminotransferase (${\beta}=0.064$, P = 0.029), and total bilirubin (${\beta}=-0.881$, P = 0.009). In multiple logistic regression analysis, increased CAP was independently associated with increased metabolic syndrome risk (per 10 dB/m increase; odds ratio, 1.093; 95% confidence interval, 1.009-1.183; P = 0.029) even after adjusting for multiple confounding factors. Conclusion: Increased CAP measured with transient elastography significantly correlated with and could predict increased metabolic syndrome risk in chronic kidney disease patients.

• Korean Journal of Social Welfare Studies
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• v.49 no.3
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• pp.247-275
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• 2018

In the absence of a research study on meta-analysis in terms of program development, the purpose of the study is to analyze the contents of the meta-analysis research studies which has been conducted for 18 years, and is to identify the level of program component evidence for the development of social work program. In order to achieve these purposes, the study analyzed the feature and usefulness of the 110 meta-analysis studies(5,781 program evaluation studies)published from 2010 to June 2017 in major academic journals related to the areas of the social welfare, psychology, counseling and health. The major findings are as follows. The 110 meta-analysis studies tended to narrow down the scope of the population, problems, and program types, but they also included a lot of heterogeneous types. In the statistical methods, there were relatively few studies to explain the factors behind the heterogeneity of program effectiveness. In addition, researchers tended to select program components arbitrarily with bias on specific components. The important program components with the statistical validity are as follows; the age of the subjects, the severity of the problem, the expertise of the providers, and the strength and activities of the intervention, The academic meanings of the study results was discussed, and the direction of future research was presented to increase the usefulness of the metaanalysis for program development.

• Korean Journal of Psychosomatic Medicine
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• v.24 no.1
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• pp.3-8
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• 2016

Functional dyspepsia is one of the most common bowel disorders as prevalent of 7.7% Korean population. The cardinal manifestations include bothersome postprandial fullness, early satiation, epigastric burning or pain. These features are chronic and should be presented recurrently with no other compatible organic disease to explain the symptoms. Even though it is not life-shortening, functional dyspepsia usually make the health-related quality of life worse especially if other functional bowel disorder coexist. The coexistence of functional bowel disorders is called as 'overlap syndrome'. Anxiety, somatization and insomnia is more prevalent in overlap syndrome compared with sole functional bowel disorder. Therefore, it is worthwhile that physician interviews and elucidates whether the dyspeptic patient had other kinds of functional bowel disorders, and manages the underlying psychotic pathology. Placebo effect is large in functional dyspepsia, and there is only four kinds of prokinetics that is proven to be superior to placebo. Adverse events relating prolonged administration of prokinetics sometimes fatal or irreversible, physician willing to describe prokinetics should be familiar to the possible adverse effects and the relating risk factors. Pathologic acid reflux is not uncommon in functional dyspepsia, and acid-suppressant is equivalent to the prokientics in most of dyspeptic patients.

• Land and Housing Review
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• v.12 no.2
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• pp.61-78
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• 2021

This study aims to understand the thematic trends globally developed in the 'Green Urbanism' related research. Research methodology is based on systemic review of international literature published for the past 20 years period between 2000 and 2020. The specific methods applied include not only literature search by citation, co-authorship, and co-occurrence but social network analysis in order to find correlations among the publication. The correlations are visualized and analysed using VOSviewer and Ucinet software. The analysis indicates that total of 51 studies were carried out by 89 authors from 54 institutions across 21 countries during the period. The majority of the research was done by a country-specific study and only a few research were collaborative studies with other countries. The most common theme that occurred in the early years was 'sustainability and the theme evolved toward specific ones such as 'built environment', 'infrastructure', and 'health'. Having considered that climate change has become a global challenge, green urbanism is expected to be a future direction to pursue environmentally sustainable urban spaces. This study also implies that governance, policy support, and intervention are crucial factors in developing sustainable urban spaces.

• Korean Journal of Labor Studies
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• v.24 no.3
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• pp.35-71
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• 2018

The purpose of this study is to examine which job-related factors are associated with presenteeism, which is defined as attending work while ill. Although presenteeism is a relatively new concept in academic research, it should be regarded as an important social issue in that presenteeism threatens employees' job prospects and quality of life as well as it causes loss of work productivity. I analyzed a cross-sectional survey of 24,571 wage workers over 15 from the fourth wave of the Korean Working Conditions Survey in 2014. Five logistic regression models were analyzed on experience of presenteeism, and work hours and private life, occupational environment, job insecurity, rewards and welfare were assessed as key predictors of presenteeism. I found that 1) work hours with bad fit with private life, 2) high level of work time-pressure, and low job satisfaction 3) job insecurity, and 4) low benefits are associated with experience of presenteeism. The findings are fairly consistent with the theory of job-person mismatch, which explains that workers tend to preserve their personal resources by going to work while ill (presenteeism) when job demands or work conditions do not match with their level of personal expectation and, thus, workers are afraid of loss of personal resources. Presenteeism influences worker's long-term health and quality of life negatively as well as causes serious social costs. Therefore, we need organizational efforts to prevent the negative effects of presenteeism on society as well as workers.

• The Journal of the Korea Contents Association
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• v.18 no.11
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• pp.516-526
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• 2018

Purpose: This study is to identify how depression, anxiety and social support influence on suicidal ideation of Parkinson disease patients related to general characteristics. Methods: This descriptive correlative study was conducted through an organized and structured questionnaire and 120 sampled Parkinson disease patients. Collected data was analyzed by t-tests, ANOVA, and Preason's correlation coefficient and multiple regression analysis using SPSS 19.0. Results : Finding revealed 1) The degrees of suicidal ideation were significantly different upon the martial status(F=3.37, p=.021) among groups, drinking(F=4.97, p=.008) and smoking history(F=4.77, p=.010): 2) Pearson's correlation coefficient indicated significant association among the depression, anxiety, social support and suicidal ideation 3) Multiple regression analysis showed depression(${\beta}=.58$ t=7.77, p<.001), social support(${\beta}=-.21$, t=-2.69, p=.008) and alcohol drinking(${\beta}=.17$ t=2.61, p=.010). Depression was the major influencing factor and it has 54% of explanation power. Conclusion: Based on the findings of this study, health professionals should provide parkinson disease patients with comprehensive and appropriate management method to prevent suicide ideation upon factors: depression, anxiety and social support to prevent suicide ideation. Especially, implement of self-help group program to parkinson disease patients is very needed.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.2
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• pp.164-171
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• 2018

Objectives : Depression is a common mental illness and a major cause of suicide. Although serum lipids have been associated with depression and suicide, there has been much debate. In this study, we investigated the relationship between depression, suicide, and serum lipids in patients admitted with depressed mood. Methods : A total of 134 subjects were divided into 86 non-suicide patients and 48 suicide attempters. The serum lipid levels and sub-scores of the Korean Symptom Checklist-95 (KSCL95) were compared. We also investigated the relationship between serum lipids and sub-scores of KSCL95 and investigated whether serum lipids were risk factors for suicide attempts. Results : There was no difference in serum lipids between the two groups. Among the sub-items of KSCL95, obsession was higher in non-suicide group. Triglyceride showed positive correlations with anxiety, phobic anxiety, agoraphobia, schizophrenia, and self-regulation problem. High triglyceride was a risk factor for suicide attempts. Conclusions : Triglyceride is associated with depression, anxiety, and self - regulation, and high serum triglyceride levels may be a risk factor for suicide attempts.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.118-127
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• 2019

This study was conducted to provide data for the development of health program to promote patient safety nursing activities by analyzing the effect of perception of importance of patient safety management, perceptions of patient safety culture and organizational communication on patient safety nursing activities in small & medium hospital nurses. Data collection was conducted from February 8 to 15, 2019. A total of 202 questionnaires were administered to nurses who have worked for more than six months in three small and medium hospitals. The perception of importance of patient safety management of the subjects was $3.60{\pm}.49$, perception of patient safety culture was $3.39{\pm}.41$, organizational communication was $3.29{\pm}.45$ and patient safety nursing activities was $4.08{\pm}.50$. The patient safety nursing activities was related to perception of importance of patient safety management(r=.597, p<.001), perception of patient safety culture(r=.626, p<.001), organizational communication(r=.559, p<.001), there was a significant positive correlation. Perception of importance of patient safety management(${\beta}=.258$, p=.001), perception of patient safety culture(${\beta}=.323$, p<.001) and organizational communication(${\beta}=.160$, p=.044) had a significant effect on patient safety nursing activities(F=53.067, p<.001). The explanatory power of these variables was 43.7%.