• 제목/요약/키워드: health risk assessment

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Adequacy Evaluation of Fish Intake Parameter used for Human Health Risk Assessment to Derive Freshwater Quality Criteria in Korea (국내담수지역 인체위해성기반 준거치 산정에 활용되는 어류섭취량인자 타당성 평가)

  • An, Youn-Joo;Nam, Sun-Hwa
    • Journal of Korean Society on Water Environment
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    • v.27 no.3
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    • pp.364-370
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    • 2011
  • Water quality criteria for human health protection are derived based on the human health risk assessment. Water quality criteria in Korean freshwater bodies have been derived according to the equations developed by the US Environmental Protection Agency. The equations include the fish intake parameter, which is very important factor that significantly influences on the criteria derivation. So far, several fish intake values were used in human health risk assessment for water quality standards and effluent standards. However, these values are not consistent and they refer to various sources. Therefore, there is a need to suggest the most appropriate value of fish intake parameter to derive freshwater quality criteria in Korea. In this study, national and international fish intake values were widely collected and evaluated to select the adequate value of fish intake parameter that can be applied in Korea. The USEPA presented fish intake parameter as the 17.5 g/day for general adults and sport fishers and 142.4 g/day for subsistence fishers. In Korean reports, wide range values of 2 to 67.7 g/day were suggested as fish intake value. These values included finfish and shellfish intakes in common but had various habits. This study found that the 52.4 g/day suggested in Korean Exposure Factors Handbook published by the Ministry of Environment in 2007 seemed to be the suitable fish intake parameter to derive the freshwater quality criteria in Korea. The value is based on water corrected intakes of finfish and shellfish present in freshwater and coastal areas. We expect that this report can be useful to select suitable fish intake value in human health risk assessment for establishing freshwater quality standard in Korea.

Safety and Risk Assessment of Arsenic in Drinking Water (음용수를 통한 비소 노출의 인체 안전성 평가)

  • 이무열;정진호
    • Toxicological Research
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    • v.18 no.2
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    • pp.107-116
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    • 2002
  • Arsenic (As) is a ubiquitous element found in several forms in foods and water. Although certain foods, such as marine fish, contain substantial levels of organic arsenic forms, they are relatively low in toxicity compared to inorganic forms. in contrast, arsenic in drinking water is predominantly inorganic and highly toxic. Chronic ingestion of arsenic-contaminated drinking water is therefore the major pathway posing potential risk to human hearth. since the early 1990s in Bangladesh ozone, arsenic exposure has caused more than 7,000 deaths and uncounted thousands shout symptoms of long-term arsenic poisoning. Significant portion of world populations are exposed to low to moderate levels of arsenic of parts per billion (ppb) to hundreds of ppb. As a consequence, the World Health Organization (WHO) and U.S. environmental health agencies, such as the Environmental Protection Agency (EPA) made arsenic their highest priority. Recently, the WHO, European Union (EU), and US. EPA lowered an acceptable level of 10 ppb for arsenic in drinking water In this article, various health effects of arsenic in drinking water were reviewed and the current status for risk assessment to regulate arsenic in drinking water was discussed.

Research on Improvement Measures for Chemical Risk Assessment for Small and Medium-Sized Businesses (중소규모 사업장을 위한 화학물질 위험성평가 개선방안 연구)

  • Ji Ung Choi;Woo Sub Shim
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.5
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    • pp.845-853
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    • 2023
  • The Ministry of Employment and Labor announced a roadmap for reducing serious accidents to create a "safe and healthy workplace, happy Korea" and ordered a risk assessment for all work processes in all workplaces on November 30, 2022. Accordingly, even workplaces that handle new chemicals must conduct risk assessment when introducing new chemicals, but the risk assessment techniques currently proposed by the government focus on preventing conventional accidents such as falls, getting caught, and bumping. Currently, there is a Chemical Hazard Risk Management (CHARM) technique that is most commonly used for chemical risk assessment, but in small and medium-sized businesses that lack professional manpower related to chemical substances, there are many technical terms in the technique and it is difficult to interpret, so its utilization is very low. Therefore, the purpose of this study is to present a method that can make risk assessment easier and simpler before handling new chemicals so that it can be used well in small and medium-sized businesses that lack professional manpower related to chemical substances. Through actual cases, the method of using CHARM was confirmed step by step, and based on this, risk reduction establishment and execution methods were derived. Based on the results of this study, it is expected that it will be used as the best tool for preventing accidents such as acute poisoning when handling chemicals in small and medium-sized workplaces that lack professional manpower related to chemical substances and make every effort to protect workers' health.

Environmental Risk Assessment for Ivermectin, Praziquantel, Tamiflu and Triclosan (Ivermectin, praziquantel, tamiflu, triclosan의 환경위해성평가)

  • Ryu, Taekwon;Kim, Jungkon;Kim, Kyungtae;Lee, Jaewoo;Kim, Jieun;Cho, Jaegu;Yoon, Junheon;Lee, Jaean;Kim, Pilje;Ryu, Jisung
    • Journal of Environmental Health Sciences
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    • v.44 no.2
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    • pp.196-203
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    • 2018
  • Objectives: The purpose of this study was to assess environmental risk on the emerging contaminants of concern, such as ivermetin, parziquantel, tamiflu and triclosan. Furthermore, we tried to provide a more efficient management practice and a basis for future studies of risk assessment on those substances. Methods: Predicted no effect concentration (PNEC) and predicted environmental concentration (PEC) were determined through modeling and literature reviews. Environmental risk assessment was evaluated by calculating HQ (hazard quotient) by a comparison of PEC (or measured environmental concentration (MEC)) and PNEC. Results: HQ value of tamiflu calculated from MEC was 1.9E-03. For ivermectin and triclosan, the HQ values were not available because these were not detected in the aquatic environment. The toxicity of ivermectin and triclosan showed a very low value, indicating a high level of HQ. However, praziquantel can be categorized into the material that do not require management since they have less than HQ 1. Conclusion: Based on the results of the initial risk assessment, it is assumed that the ivermectin and triclosan have potential to cause direct adverse effects on the aquatic environment. To conduct an accurate environmental risk assessment, the further study on PEC estimation of such contaminants should be actively carried out.

A Case Study on the Estimation of the Risk based on Statistics (산업재해통계기반 Risk 산정에 관한 연구)

  • Woo, Jong-Gwon;Lee, Mi-Jeong;Seol, Mun-Su;Baek, Jong-Bae
    • Journal of the Korean Society of Safety
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    • v.36 no.4
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    • pp.80-87
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    • 2021
  • Risk assessment techniques are processes used to evaluate hazardous risk factors in construction sites, facilities, raw materials, machinery, and equipment, and to estimate the size of risk that could lead to injury or disease, and establish countermeasures. The most important thing in assessing risk is calculating the size of the risk. If the size of the risk cannot be calculated objectively and quantitatively, all members who participated in the evaluation would passively engage in establishing and implementing appropriate measures. Therefore, this study focused on predicting accidents that are expected to occur in the future based on past occupational accident statistics, and quantifying the size of the risk in an overview. The technique employed in this study differs from other risk assessment techniques in that the subjective elements of evaluators were excluded as much as possible by utilizing past occupational accident statistics. This study aims to calculate the size of the risk, regardless of evaluators, such as a manager, supervisor, safety manager, or employee. The size of the risk is the combination of the likelihood and severity of an accident. In this study, the likelihood of an accident was evaluated using the theory of Bud Accident Chainability, and the severity of an accident was calculated using the occupational accident statistics over the past five years according to the accident classification by the International Labor Organization.

Association Between Prophylactic Antibiotic Use and Surgical Site Infection Based on Quality Assessment Data in Korea (요양급여적정성 평가자료를 이용한 예방적 항생제 사용과 수술부위 감염 발생의 관련성 연구)

  • Kim, Kyoung-Hoon;Park, Choon-Seon;Chang, Jin-Hee;Kim, Nam-Soon;Lee, Jin-Seo;Choi, Bo-Ram;Lee, Byung-Ran;Lee, Kyoo-Duck;Kim, Sun-Min;Yeom, Seon-A
    • Journal of Preventive Medicine and Public Health
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    • v.43 no.3
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    • pp.235-244
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    • 2010
  • Objectives: To examine the prophylactic antibiotic use in reducing surgical site infection. Methods: This was a retrospective study for patients aged 18 years and older who underwent gastrectomy, cholecystectomy, colectomy, cesarean section and hysterectomy. The data source was quality assessment data of the Health Insurance Review & Assessment Service gathered from medical records of 302 national hospitals. Prophylactic antibiotic use was defined as: timely antibiotic administration or inappropriate antibiotic selection. We performed hierarchical logistic regression to examine the association between prophylactic antibiotic use and surgical site infection with adjustment for covariates. Results: The study population consisted of 16 348 patients (1588 gastrectomies, 2327 cholecystectomies, 1,384 colectomies, 3977 hysterectomies and 7072 cesarean sections) and surgical site infection was identified in 351 (2.1%) patients. The rates of timely antibiotic administration and inappropriate antibiotic selection varied according to procedures. Cholecystectomy patients who received timely prophylactic antibiotic had a significantly reduced risk of surgical site infection compared with those who did not receive a timely prophylactic antibiotics (OR 0.64, 95% CI=0.50-0.83), but no significant reduction was observed for other procedures. When inappropriate prophylactic antibiotics were given, the risk of surgical site infection significantly increased: 8.26-fold (95% CI=4.34-15.7) for gastrectomy, 4.73-fold (95% CI=2.09-10.7) for colectomy, 2.34-fold (95% CI=1.14-4.80) for cesarean section, 4.03-fold (95% CI=1.93-8.42) for hysterectomy. Conclusions: This study examines the association among timely antibiotic administration, inappropriate antibiotic selection and surgical site infection. Patients who received timely and appropriate antibiotics had a decreased risk of surgical site infection. Efforts to improve the timing of antibiotic administration and use of appropriate antibiotic are needed to lower the risk of surgical site infection.

A Study on the Standards of Volatile Organic Compounds in Indoor Air of Office (사무실 실내공기중 휘발성유기화합물의 기준설정에 관한 연구)

  • Kim, Yoon-Shin;Lee, Cheol-Min;Roh, Young-Man;Lee, So-Dam;Sohn, Jong-Ryeul;Kim, Seok-Won
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.16 no.4
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    • pp.413-427
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    • 2006
  • It is necessary to study and develop guidelines for providing comfort and health indoor air quality for office workers since air-tight envelope system of current office building may cause poor indoor air quality. The purpose of this study is to propose guideline for volatile organic compounds in office base on the field study, human health risk assessment and cost-benefit analysis. The field study was conducted to survey the concentrations of volatile organic compounds in indoor air of 69 offices from June to September, 2005 in Seoul and Gyeonggi-do. The rate of excess to guideline of volatile organic compounds in indoor air of new apartment on the Ministry of Environment in Korea(MOE) was surveyed 37.6% for benzene, 6.8% for toluene, and 1.5% for ethylbenzene. As the result of human health risk assessment, mean cancer risk did not exceed 10-6 which is guideline of US.EPA. Also, total hazard index did not exceed 1 which is guideline of US.EPA. Through the cost-benefit analysis of angle on the social-economics to verify the necessary to establish the standards of volatile organic compounds for improvement and development of indoor air quality in office, the present value of benefit was higher than the present value of cost. With the above considerations in mind, it is suggested that the field study for indoor air quality in offices should be expanded and human health risk assessment and cost-benefit analysis be performed th offer scientific data for decision-making of policy for improvement and management of indoor air quality in office.

Risk Assessment of exposure to the extinguishing agents using CHARM (CHARM을 통한 소화약제 위험성 평가에 관한 연구)

  • Cho, Jung Rae;Jung, Tae Hwan
    • Journal of Korean Society of Disaster and Security
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    • v.10 no.2
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    • pp.35-41
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    • 2017
  • Recently chemical intoxication related with the use of chemical extinguishing agents occurs frequently. With the industrialization, high-rising of building and increase of fire risk, we use the various extinguishing agents and the safe use become important. In this study I carried out the risk assessment of representative chemical extinguishing agents (HCFC-123, HFC-125) using the CHARM and got the meaningful qualitative outcome. This study is significant in that the risk assessment of chemicals was conducted using CHARM, chemical risk assessment tool. It is expected that the results will be utilized as the basic data for the national chemical safety management.

Ecological Risk Assessment of Chemicals of Concern for Initiation of Ecorisk-based Water Quality Standards in Korea (생태수질기준설정을 위한 대상물질의 생태위해성 평가)

  • An, Youn-Joo;Nam, Sun-Hwa;Kim, Yong-Hwa
    • Journal of Korean Society on Water Environment
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    • v.24 no.5
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    • pp.592-597
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    • 2008
  • Current water quality standard (WQS) in Korea is based on the protection of human health, not considering the protection of aquatic organisms. Most of chemicals can be toxic to ecological biota as well as human. Health of aquatic biota is closely related to the human health via food chain, therefore ecological risk based-WQS needs to be developed to protect the aquatic ecosystem. In this study, we selected the 31 chemicals in the Project entitled 'Development of integrated methodology for evaluation of water environment'. The methodology for calculating water quality criteria was derived from the Australian and New Zealand processes for deriving guideline trigger value for aquatic ecosystem. The available ecotoxicity data were collected from US EPA's ECOTOXicology Database (ECOTOX), TOX-2000 Database, European Chemicals Bureau (ECB)'s International Uniform Chemical Information Database (IUCLID) and Environmental Protection Agency (US EPA)'s report 'Ambient Water Quality Criteria (AWQC)'. The aquatic toxicity data for the Korean species were selected for risk assessment to reflect the Korean water environment. The monitoring values were calculated from the water quality monitoring data four main Korean rivers. We suggested the order of priorities of chemicals based on ecological risk assessment. We expect that these results can be useful information for establishing the WQS for the protection of aquatic ecosystem.

A study on the Research & Analysis of the Health and safety Managing's Understanding for practical Application of Construction Industry Risk Assessment - Focus on worker - (건설업 위험성평가 실무적 적용을 위한 안전보건 인식도 조사 연구 -근로자를 중심으로-)

  • Choe, Su-Hwan;O, Tae-Geun;Lee, Yeon-Su;Lee, Jin-Seop
    • Proceedings of the Safety Management and Science Conference
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    • 2013.04a
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    • pp.445-456
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    • 2013
  • According to Department of labor guideline "2012-104 (2012.9.26.)" This study is to suggest the basic information and the improvement for the application of risk assessment on a construction site by group interview & survey of construction worker who is the practice of the subject and then numerical analysis about awareness and action plan of Safety and health. The result of group interview and survey of construction worker, most of construction worker feel the danger during the work. Then construction worker analysis results that risk assessment helps to change & raise awareness of safety and reduce an industrial disaster. Easy Safety management activity such as TBM & safety education active will be necessary for safe worksite and then I suggest the TBT(tool box talk) active which combines TBM & safety education.

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