• 경영과정보연구
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• 제16권
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• pp.139-159
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• 2005

In many countries the demographics clearly informs us that an aging population represent a serious problem. To this extent senior citizens welfare does matter it has developed into a public debate and genuine concern. it seems that the social issues are focused on how the socity views the social welfare policies. In a modern welfare state where the emphasis lies in pursing a high standard of living and thereby high quality of life. This does not cover the very well the old people in society, but the government clearly carries an obligation to look after and care for the retired & old people in the society. This obligation the social and economic impact that an old person faces as he/she grows old. it is important ensure that their lives carries a meaning and that they as a group will not be estranged from the mainstream of society just because they are considered to be part of the aging population. The key issues that must be addressed are 1) The impact of reduced spending power from less income. a lower income stream; 2) increasing health problems and costs; 3) the natural degradation of ones physical & mental powers; 4) and thereby an isolation from the public in general. So clearly the social policy related to the old people in society should be developed with the consent of what they believe is important to them. To ensure their minimum income level that a beneficiary of an old person's pension will receive, the monthly pension should be reflected by the official price index and be adjusted accordingly. by making the job market open for the senior citizens, expending the mandatory retirement age, give companiesincentives to hire senior citizens, there maybe an opportunity to extend to the aging population the possibility to continue to participate in the society at large.

• Journal of Microbiology and Biotechnology
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• 제28권1호
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• pp.1-11
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• 2018

An antioxidant peptide derived from Pinctada fucata meat using an Alcalase2.4L enzymatic hydrolysis method (named AOP) and identified by LC-TOF-MS has promising clinical potential for generating cosmetic products that protect skin from sunshine. To date, there have been few published studies investigating the structure-activity relationship in these peptides. To prepare antioxidant peptides better and improve their stability, the design and expression of an antioxidant peptide from Pinctada fucata (named DSAOP) was studied. The peptide contains a common precursor of an expression vector containing an ${\alpha}$-helix tandemly linked according to the BamHI restriction sites. The DNA fragments encoding DSAOP were synthesized and subcloned into the expression vector pET-30a (+), and the peptide was expressed mostly as soluble protein in recombinant Escherichia coli. Meanwhile, the DPPH radical scavenging activity, superoxide radical scavenging activity, and hydroxyl radical scavenging activity of DSAOP $IC_{50}$ values were $0.136{\pm}0.006$, $0.625{\pm}0.025$, and $0.306{\pm}0.015mg/ml$, respectively, with 2-fold higher DPPH radical scavenging activity compared with chemosynthesized AOP (p < 0.05), as well as higher superoxide radical scavenging activity compared with natural AOP (p < 0.05). This preparation method was at the international advanced level. Furthermore, pilot-scale production results showed that DSAOP was expressed successfully in fermenter cultures, which indicated that the design strategy and expression methods would be useful for obtaining substantial amounts of stable peptides at low costs. These results showed that DSAOP produced with recombinant Escherichia coli could be useful in cosmetic skin care products, health foods, and pharmaceuticals.

• 한국농촌생활과학회지
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• 제6권2호
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• pp.109-119
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• 1995

The objectives of this study were 1) to identity the living conditions of old women at rural area, 2) to inquire of the activities for extra income 3) to Provide information on the social service program development for old rural women. Data were collected by interview with the questionaire from 396 old rural women in Korea. In analyzing data, $x^2$-test has been produced by S A S program package at Rural Development Administration. The major results were as follows ; 1. The average age was 69.7years old of the subjects, illiteracy was 54.1%, widows was 58.6%, and the 18.4% of elderly have led a solitary life. Also, the degree of health care was very low. 2. The source of living costs in most old rural women lay on agricultural income. Also, because of the educational expenditure for their children, etc., they led to poverty, and then could not provide for their old age. 3. In spite of the 60.4% of the old women did farming, a lot of them wishes to have a side job. The reasons why they wish to do a side job were making money, spending their time in working, being proud before their children, etc.. 4. According as they rely on their husband, the eldest son and his wife, for the psychological, physical, economical support, their position among family was low. Therefore, only the 43.3% of old women were satisfied with their life. 5. Finally, in the result of this case study, the old women, who particpate in the extra income promoting program, were satisfied with their rural life, and their social position were high rather than elswhere.

• 한국간호교육학회지
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• 제5권1호
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• pp.7-19
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• 1999

The purpose of this study was to examine nursing college students' knowledge of and attitudes toward brain death, organ donation and organ transplantation. The research design utilized in this study was a descriptive research design. The data were collected from September 7 to 14, 1998, by means of strutted questionnaire. To measure students' knowledge of brain death, organ donation and organ transplantation, Joo's(1995) instrument was used. The questionnaire was composed of 22 items. To measure students' attitudes toward organ donation and organ transplantation, s(1995) Instrument was used. The questionnaire was composed of 22 items. The data were analyzed by frequency, t-test, ANOVA, and Pearson's Correlation Coefficient using the SAS program. The results were as follows : 1. Students' knowledge of brain death, organ donation and organ transplantation was 9-20. The mean score was 15.36, with 22, the highest possible score. There was statistically significant difference between students' knowledge and approval on the brain death recognition group(t=9.75, p=0.002). 2. Students' altitudes toward organ do nation and organ transplantation showed is mean score of 3.61 on a 5 attitudes points Liken scale. More than 80% of respondents agreed that organ transplantation can offer a high quality of life to the recipient and is an acceptable form of medical treatment. The health care costs associated with organ transplantation are worth itif another's life can be saved. Students felt it important to help others who are very ill. Also, by donating organs, students felt a part of their own body would continue to live by making it possible for someone else to live. Only 2.9% of students objected to organ donation for religious reasons. There was statistically significant difference among students' attitudes, experienced blood donor group(t=17.04, p=0.000), approval on the brain death recognition group (t=21.06, p=0.000), organ donation agreement group(t=46.13, p=0.000).

• 가정과삶의질연구
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• 제27권1호
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• pp.61-71
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• 2009

The purpose of this study was to resolve the issues of inferior housing environment and the population decrease in rural community by improving the environment and attracting urban inhabitants. A simulation on the costs and the local programs was operated from a point of view that Pension Insurance House with Long-term Lease and a plan for the program in connection with local resources should be accompanied to attract urban inhabitants. The study was carried out through mainly documents analysis and specialists' opinions. The simulation results are as follows. Firstly, the pre-existing rural housing development projects have only emphasized the hardware, while underestimated the post-management with operating programs. The software should be underlined when Pension Insurance House is developed. Secondly, as a result of the simulation on construction expenditure and the operating and maintenance cost for 30 years, about 82.3 million Wons are necessary residential expenses for 15 years per unit. Thirdly, in case of MUJU County, it has made the most of its pre-existing institutions. It's medical institutions provide medical care system with health education, facilities related leisure and culture offer recreational programs and the local community center and its program of each town helps new habitants adopt to the rural life. Additionally, the employment project of a local welfare center allow people living in a rural community to continue their careers with their talents and interests through local class programs for a life worth living. Lastly, guide for getting information of rural life, local community gathering and preliminary education should be carried out to reduce expectant tenants' incompatibility and assist them settle down early. The community program expansion is also required at the local government level.

• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.9015-9019
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• 2014

The study aimed to compare the 2 main types of insurance used by colorectal cancer (CRC) patients in a university hospital in Thailand: universal coverage (UC) and 'Civil Servant Medical Benefit Scheme' (CSMBS) in terms of hospital expenditure and survival outcomes. CRC cases in stages I-IV who were operated on and had completed their adjuvant therapy in Songklanagarind Hospital from 2004 through 2013 were retrospectively reviewed regarding their hospital expenditure, focusing on surgical and chemotherapy costs. Of 1,013 cases analyzed, 524 (51.7%) were in the UC group while 489 (48.3%) belonged to the CSMBS group. Cases with stage IV disease were significantly more frequent in the UC group. Average total treatment expenditure (TTE) was 143,780 Thai Baht (THB) (1 US$ =~ 30 THB). The TTE increased with tumor stage and the chemotherapy cost contributed the most to the TTE increment. TTE in the CSMBS group was significantly higher than in the UC group for stage II-III CRCs. The majority of cases in the UC group (65.5%) used deGramont or Mayo as their first line regimen, and the proportion of cases who started with a capecitabine-based regimen (XELOX or $Xeloda^{(R)}$) was significantly higher in the CSMBS group (61.0% compared to 24.5% in the UC group, p-value < 0.01). On survival analysis, overall survival (OS) and progress free survival in the CSMBS group were significantly better than in the UC group. The 5-year OS in the CSMBS and UC groups were 84.3% and 74.6%, respectively (p-value < 0.01). In conclusion, the study indicates that in Thailand, the type of insurance influences resource utilization, especially the choice of chemotherapy, in CRC cases. This disparity in treatment, in turn, results in a gap in treatment outcomes.

• 셀메드
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• 제9권1호
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• pp.3.1-3.5
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• 2019

Bronchial asthma is one of the most common chronic diseases globally and currently affects approximately 300 million people worldwide. As per scientific data, approximately 10-12% of adults; and 15% of children are affected by the disease. The increasing global prevalence of the disease imposes a high health care costs into its mechanisms and treatment. Unani system of medicine (USM) is a well known traditional therapy for number of diseases since ancient times. Time has proved that USM has a special role in treatment of chronic diseases, due its special Usooleillaj (Line of treatment). Dhiq al-Nafas (bronchial asthma) is also considered as a chronic disease. Since ancient times, the disease was cured by number of single as well as compound formulations by renowned Unani scholars. This review provides a comprehensive summary of medicinal plant throughout the world, with reference to renowned Unani scholars and physicians for treatment of Dhiq al-Nafas. A number of Unani single and compound drugs, highly efficacious and safe drugs are available for the asthma. The data were taken from classical literature of USM, Modern reference books & electronic journals. The recent information was collected from different authentic search engines. This review will provide the centuries therapeutic information's of classical literature and recent scientific studies of 12 herbal drugs mentioned in USM, which will help the academia, clinicians, research scholars and post graduate students from Unani Medicine, Traditional & Complementary Medicine and other related disciplines, having research interest or work in the Unani medicine.

• 한국인터넷방송통신학회논문지
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• 제19권1호
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• pp.187-195
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• 2019

최근 빅데이터 관련 기술들이 발전함에 따라 다양한 분야에서 생성되는 데이터들을 수집하여 저장하고 처리 및 분석할 수 있게 되었다. 이러한 빅데이터 기술들을 임상 결과 분석에 활용하고, 임상시험 설계 최적화를 통해 보건의료분야에 투입되는 막대한 비용을 절감할 수 있을 것으로 전망된다. 따라서 본 논문에서는 임상 결과를 분석하여 임상시험 기간과 비용 등을 줄일 수 있는 가이드 정보를 제시하고자 한다. 먼저 Sqoop을 사용하여 임상 결과 데이터가 저장된 관계형 데이터 베이스로부터 HDFS에 수집하여 저장하고, 하둡을 기반으로 동작하는 처리 도구인 Hive를 이용하여 데이터를 처리한다. 공공분야, 기업 등 각 분야에서 많이 활용되고 있는 빅데이터 분석 도구인 R을 이용하여 연관성 분석을 한다.

• 한국간담췌외과학회지
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• 제27권1호
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• pp.56-62
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• 2023

Backgrounds/Aims: Endoscopic retrograde cholangiopancreatography-guided gallbladder drainage (ERGD) is an alternative to percutaneous cholecystostomy (PTC) for hospitalized acute cholecystitis (AC) patients. Methods: We retrospectively analyzed propensity score matched (PSM) AC hospitalizations using the National Inpatient Sample database between 2016 and 2019 to compare the outcomes of ERGD and PTC. Results: After PSM, there were 3,360 AC hospitalizations, with 48.8% undergoing PTC and 51.2% undergoing ERGD. There was no difference in median length of stay between the PTC and ERGD cohorts (p = 0.110). There was a higher median hospitalization cost in the ERGD cohort, $62,562 (interquartile range [IQR] $40,707-97,978) compared to PTC, $40,413 (IQR $25,244-65,608; p < 0.001). The 30-day inpatient mortality was significantly lower in hospitalizations with ERGD compared to PTC (adjusted hazard ratio 0.16, 95% confidence interval [CI]: 0.1-0.41; p < 0.001). There was no difference in association with blood transfusions, acute renal failure, ileus, small bowel obstruction, and open cholecystectomy conversion (p > 0.05) between hospitalizations with ERGD and PTC. There was lower association of acute hypoxic respiratory failure (adjusted ratio [AOR] 0.46, 95% CI: 0.29-0.72; p = 0.001), hypovolemia (AOR 0.66, 95% CI: 0.49-0.82; p = 0.009) and higher association of lower gastrointestinal bleed (AOR 1.94, 95% CI: 1.48-2.54; p < 0.001) with ERGD compared to PTC. Conclusions: ERGD is a safer alternative to PTC in patients with AC. The risk complications are lower in ERGD compared to PTC but no difference exists based on mortality or conversion to open cholecystectomy.

• 문화기술의 융합
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• 제1권4호
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• pp.87-101
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• 2015

본 연구는 당뇨병 질환자의 의료이용 및 의료비를 통하여 직접의료비를 조사하고자 하였다. 본 연구를 위하여 2012년 한국의료패널 총 5,434가구, 15,872명을 이용하여 만19세 이상 당뇨병 질환자는 812명을 대상으로 하였다. 연구방법은 응급의료이용, 입원의료이용, 외래의료이용에 대한 평균 의료비와 직접의료비(환자본인부담의료비+공단부담금+비급여본인부담금)를 구하였고, 년간총직접비용은 직접의료비에 당뇨병유병율(N)을 곱하여 산출하였다. 연구결과, 당뇨병 질환자의 100명당 평균 응급의료이용횟수는 1.98회 의료비, 총직접비용, 년간총직접비용은 85,942원, 447,359원, 363,255,508원이었고, 입원의료이용횟수는 5.6회 의료비, 총직접비용, 년간총직접비용은 772,240원, 4,061,982원 3,298,329,384원 이였으며, 외래의료이용횟수는 10회 의료비, 총직접비용, 년간총직접비용은 11,978원, 26,020원, 21,128,240원 이였다. 이상과 같은 결과를 바탕으로 다음과 같은 결론을 얻었다. 당뇨병의 발생은 의료비증가와 직접의료비 증가에 영향을 미칠 수 있으며, 이는 가구 및 환자에 있어 큰 부담이며 삶의 질도 낮아질 것이다. 당뇨병 질환의 감소를 위한 식생활. 운동 혈당, 혈압 등의 조기진단과 예방을 위한 관리가 중요하다.