Introduction: The surgical treatment of Graves' disease has several advantage such as rapid and long lasting therapeutic effect, relatively low incidence of postoperative hypothyroidism and recurrence. Because of less frequent but serious postoperative complications, the operation have not been casually used for treatment of Graves' disease. Hypoclacemia, hoarseness and hematomas are common complications after operative treatment. However, the causative mechanisms of these complications have not been well explained. Objective: We aimed to analyze the risk factors affecting the occurance of complications in surgical treatment for Graves' disease and to evaluate what are the causative mechanisms of postoperative complications. Patients and Methods: From January 1985 to December 1998, a total of 668 surgically treated patients for Graves' disease were enrolled in this study. The incidence of postoperative complications were analyzed in relation to types of surgery, preoperaive preparation, specimen weight, bleeding amount and remnant weight. Results: Postoperative complication was developed in 108(16.2%) of 668 patients. The most common complication was transient hypocalcemia in 85 cases(12.7%). Other complications were: Hematoma in 9 cases(1.3%), transient hoarseness in 5 cases(0.7%), permanent hypocalcemia in 6 cases(0.9%), permanent hoarseness in 3 case(0.4%). The important etiologic factors affecting the occurance of complications were preoperative preparation, perioperative thyroid weight, and remnant thyroid weight. Since 1993, the incidence of complication was more decreased than that in before. Conclusion: To decrease the incidence of postoperative complications of Graves' disease, the patients should be selected carefully, sufficient preoperative preparation should be achieved, and the operation should be performed by well-experienced surgeons.
Background and Objectives : Panax ginseng C.A. Meyer is a medical plant that has been widely utilized as a tonic and nutritional agent since ancient times in Korea. Ginseng has anti-metastatic property of cancer and immunomodulating activity. The novel acidic polysaccharide compound(MB40) was isolated from the leaves of Panax ginseng C.A. Meyer. To determine immunomodulating activities of MB40, we evaluate anti-cancer and anti-metastatic effects of MB40 in tumor bearing immune competent mice. Material and Methods : C3H mice were divided into three equal groups(Cisplatin treatment group, MB40 treat-ment group, Cisplatin and MB40 treatment group) and were transplanted SCC(Squamous Cell Carcinoma) cells(2${\times}$106) to the lateral side of abdomen. From day 4 after transplantation, MB40 was administrated at dose of 10mg/kg, respectively, every other day by intratumoral injection. Cisplatin was systemically administrated at doses of 1mg/kg, respectively, every week by intraperitoneal injection. Results : 5 days after administration, tumors can be palpated in every mice group. After 13 days of administration, the mice group to which MB40 were administrated exhibited reduction in tumor size respectively, compared to cisplatin group. Overall status of mice such as body weight and activity were superior in MB40 group than cisplatin group. Conclusion : The result of this study indicates MB40 may have significant therapeutic effect and decreases complications induced by systemic chemotheraphy. MB40 may be developed as a novel and potent immunotropics to improve the cell immune system and anti-cancer drug for the treatment of cancer patients in head and neck squamous cell carcinoma.
Currently changing trends of child health care is demand total health assessment of child including growth and development. This study concentrates on the growth & developmental status of low birth weight infant for help their growth & development. Thus it can be provide a direction for scientific health education and counseling materials by investigating factor of growth & development. The subjects for this study were made up of 40 low birth weight infant who attended the well baby clinic of E university Hospital. The study method used was a questionnaire & anthropometric assessment and DDST for normative data of development. The period for data collection was from July 1st to August 31th, 1982. Analysis of the data was done using percentages, $\chi$$^2$-test Stepwise Multiple Regression. The results of study were as follows. 1. The mean weight of birth was 2,068gm and mean of gestational period was 35.65 weeks. 2. The age at which weight ; 32.5%, head circumference : 67,5% chest circumference : 55.0%, height : 50. 0% was normal range of physical growth. 3. The reverse age at which social development ; 87.5%, fine motor & adaptive development ; 70.0%, gross motor development ; 72.5% of children Passed by DDST to determine of normal range of development. 4. In the among variables, it was found that the infant who were the higher emotional & verbal response of mother and stimulus environment was the more normal range of weight & development than who was not. 5. The stepwise Multiple Regression between developmental status and predictors-birth order, weight at birth, sex, antenatal care, gestational period-are accounts for 34.1%.
The study were performed genetic analysis for seed characters of 6 parents of rice cultivar and 15 $F_1$ hybrids. In terms of heritability, The highest value was observed in the character of No. of grains/spike. Second values was showed 1,000 grains weight and head rice ratio was high value than grain length and width. In an analysis of correlation relation of parent, significant positive coefficients were observed in head rice ratio and No. of grains/spike, grain length and 1,000 grains weight, but the negative coefficients were significantly revealed between grain length and No. of grains/spike. Phenotype coefficient was lowly observed in the relation of grain length and 1,000 grains weight, grain width and 1,000 grain weight that highly positive genetic coefficient was showed in an analysis of correlation relation of $F_1$. In terms of heterosis, highest value was showed 1,000 grains weight and second value was No. of grains per spike and 1,000 grains weight and second value was No. of grains per spike in terms of heterobeltiosis. In an analysis heterosis of among crossing combination, high ratio was observed 1st combination at seed length, 12th combination at seed width, 3rd combination at head rice ratio, 5th combination at 1,000 grains weight and 11th combination at No. of grains per spike. In an analysis heterobeltiosis of among crossing combination, high ratio was observed 1st combination at seed length, 12th combination at seed width, 3rd combination at head rice ratio, th combination at 1,000 grains weight and 11th combination at No. of grains per spike.
Background: Because a forward-leaning posture can cause increased back muscle activity and pain. Therefore, an innovative method to reduce back muscle activity and pain is required. Objects: This study aimed to investigate the effects of a head support on muscle activity and pain in a forward-leaning posture. Methods: A total of 14 male and 16 female students (average age, 21.65 ± 2.37 years; height, 166.15 ± 7.90 cm; and weight, 60.65 ± 9.00 kg) were recruited for the experiment. Two of them were excluded due to musculoskeletal disorders. The muscle activity and pain in the forward-leaning posture were assessed while participants washed dishes for 7 minutes with and without a head support. The condition of using a head support was randomly performed with a 5-minutes break. To confirm a lumbar flexion angle of 30° during the experiment, myoVIDEO was used, and surface electromyography was used to measure muscle activity. Pain was assessed using a 10-point visual analog scale (VAS). The Wilcoxon signed-rank test was used to analyze the data, with p < 0.05 indicating statistical significance. Results: The cervical, thoracic, and lumbar erector spinae muscle activities significantly decreased with the use of the head support, but there was no significant change in the gluteus maximus. There was a significant decrease in the VAS score for the lumbar erector spinae (p < 0.05), but there was no significant change in the VAS score for the cervical region. Conclusion: The use of a head support in a forward-leaning posture reduced cervical, thoracic, and lumbar erector muscle activity and pain. Therefore, it could be recommended during working in a forward-leaning posture, such as during dishwashing, cooking, and working as a factory employee.
Sung, Chul Hoon;Han, Sung Gil;Kim, Sung Hoon;Song, Chul Ki
Journal of the Korean Society of Manufacturing Process Engineers
/
v.18
no.6
/
pp.98-105
/
2019
In order to improve the fuel economy and dynamic behavior of automobiles, the weight reduction tendency of automobile parts is obvious. Also, in order to maximize assembly and maintenance convenience, various parts are integrated and modularized. Multi-piece methods require many manufacturing processes and become a factor of lowering the strength of parts. It is advantageous to overcome the disadvantages by integrally manufacturing to reduce the processing steps and ensure the strength of the parts. However, when it is necessary to process in a narrow space inside the part, it is impossible to process with the existing spindle. The angle head spindle is only a component of a machine tool, but it is a core part that requires high technology and is highly utilizable in products requiring high precision machining. Therefore, various and continuous studies needs for angle head spindles in areas such as vibration absorption, operational safety, excellent dimensional stability, and strength. In this paper, we propose an optimal design for angle head spindle by performing structural analysis and shape optimization for angle head spindle gear and case.
Hyun Seok, Kang;Jae Seon, Park;Tae Hwan, Kim;Sang Hyuk, Lee
Korean Journal of Head & Neck Oncology
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v.38
no.2
/
pp.23-27
/
2022
Systemic lupus erythematosus(SLE) is a multisystemic disorder of autoimmune etiology. SLE can occur commonly in young women, and the early symptoms include fever, myalgia, arthralgia, weight loss, lymphadenopathy and these nonspecific symptoms develop into skin rash, splenomegaly, serositis and encephalopathy. Diagnosis of SLE requires clinical and serologic criteria, and treatment choices are hydroxyquinolone and NSAIDs for mild disease, corticosteroids and immunosuppressant for severe disease. In lupus patient, the prevalence of lymphadenopathy is 12~59%. Although lymphadenopathy is common finding in SLE, it is hard to distinguish in early phase of SLE. A 38-year-old woman visited our hospital for cervical lymphadenopathy with polyarthritis and malaise. Multiple cervical lymph nodes enlargement was found on Neck CT, and serologic laboratory test including ANA, antiphospholipid antibody, and anti-dsDNA was positive. For excluding lymphoma, PET-CT and excisional biopsy were performed. The patient finally diagnosed with SLE, and got regular follow-up without complication.
This study has been conducted on the nonequivalent control group Pretest-posttest design in quasi experimental basis and newly born premature infants from intensive care unit of G Medical University Hospital in Inchon Metropolitan were selected in two groups of 21 infants each. The first group for experimental and the other for control. Data has been collected form October 30, 1997 to August 29, 1998. For the experimental group tactile and kinesthetic stimulation was applied 2 times a day for 10 days(10:00~ll:00 hours in the morning and 17:00~18:00 in the afternoon). As, a weight weighing instrument, electronic indicator scale(Cas Co. korea) was used. Collected data were analyzed with the SAS program using x²-test, student t-test, repeated measures ANOVA, Pearson correlated coefficient and Stepwise multiple regression. The result were as follow. 1. As for the daily weight gain, the experimental group showed first change in weight and this group also showed higher weight in the average weight than the control group. Statistically, however. there was no significant factor between the two groups. 2. In the correlation between general characteristics and weight gain, gestation Period. apgar score, admission Period before study, N.P.O. period after birth, recovery Period to birth weight showed statistical significance negative correlation with weight gam in the experimental group than control group. 3. In the factor with affected the weight gain by general characteristics showed recovery period to birth weight and head circumference in the experimental group, control group showed recovery period to birth weight, N. P. O. period after birth. admission period before study, feeding amount, weight of study. In conclusion. the sensory stimulation in this study showed a Positive aspect through there was no statistical significance in the weight gam. Tn the correlation of general characteristics and weight gam showed statistical significance negative correlation The main factor which affected the weight gain by general characteristics showed recover period to birth weight.
Kim, Junhwan;Shon, Jiyoung;Choi, Kyung-Jin;Yoon, Younghwan;Lee, Chung-Kuen
KOREAN JOURNAL OF CROP SCIENCE
/
v.58
no.2
/
pp.107-112
/
2013
The aim of this study was to test hypothesis that low sink size could mitigate deterioration of grain filling characteristics under high grain filling temperature. To achieve this aim, we selected Donganbyeo as a tolerant and Ilpumbyeo as susceptible variety to high temperature during grain filling period through screening 6 rice varieties. Then their spikelets number and the ratio of superior and inferior spikelet were compared. Grain weight and head rice ratio of Ilpumbyeo decreased significantly in high temperature. Ilpumbyeo had more spikelets than Donganbyeo. However, there was no significant difference between two varieties in the ratio of superior and inferior spikelets. So we tried to investigate the varietal difference of grain filling characteristics with removing inferior spikelets. Removing inferior spikelet in both of varieties could recover grain weight but not improve head rice ratio under high temperature. These results showed that sink/source ratio affected grain weight but didn't affect head rice ratio. Therefore, new approach was required to improve head rice ratio beyond sink/source ratio under high temperature.
The pupose of the present paper is to estimate the effects of constraint condition of pile head, ground condition(dry unit weight. $\gamma_4$) and embedded pile lengths on the behavior of single pile which is embedded in normally consolidated clay. BBperiment functions can be quantified to these effects obtained from the results of model teats. The ground of model tests is normally consolidated( NC ) clay under three kinds of effective vertical stress. The results of the model tests using the steel pile of two different embedded pile length and of free-head and fired-head show that the lateral load-deflection relationship is to be elasto plastic behavior below $\gamma_d/\gamma_{dmax}$: 0.84 and that the reduction of lateral load of beyond maximum lateral load($Q_{max}$) at each model test is significantly time-dependent. In this study, it is shown that the displacement relationship can be fitted to exponential function of time by model best results. The effect of ground conditions on the ultimate and yield lateral load is fitted to exponential function including the ratio of dry unit weight to maximum dry unit weight. When tests by results are compared with those from Broms and Budhu et at., the predicted results are over-estimated about 27-87 ayo. In effectivity of constraint condition of pile head on the lateral load-deflection response, the $Q_{fixed}/Q_{gree}-y/D$ relationship is highly non-linear and fitted to parabolic function.
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