• International Journal of Fluid Machinery and Systems
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• v.1 no.1
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• pp.101-108
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• 2008

The effect of Reynolds number on the performance of a regenerative pump was examined in a low Reynolds number range in experiment. The head of the regenerative pump increased at low flow rates and decreased at high flow rates as the Reynolds number decreased. The computation of the internal flow was made to clarify the cause of the Reynolds number effect. At low flow rates, the head is decreased with increasing the Reynolds number due to the decrease of the shear force exerted by the impeller caused by the increase of leakage and hence local flow rate. At higher flow rates, the head is increased with increasing the Reynolds number with decreased loss at the inlet and outlet as well as the decreased shear stress on the casing wall.

• Proceedings of the KSLP Conference
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• 1999.11a
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• pp.186-186
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• 1999

Tracheoesophageal fistulation following total laryngectomy has widely been used for voice restoration, This technique make exhaled air to divert to hypopharynx where phayngoesophageal segment forms the neoglottis. Even through layngectomized patients loss the normal laryngeal adjustment for speaking, it has been known that voiced and voiceless sounds are prodused in TE phonation. Nine TE speakeres were subjected to present study designed to clarity the mechanism of neoglottic adjustment in TE phonation, Fiberoptic examination and radiologic studies were performed at all patients and EMG study was performed at 3 patients during I phonation. Fiberoptic ＆ radiologic studies revealed the location of neoglottis, so called pharyngoesophargeal segment which was vibrated well. EMG activity increased for sound production at retropharyngeal prominence. These results indicated that neoglottic adjustment in TE phonation.

• Clinical and Experimental Pediatrics
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• v.50 no.1
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• pp.7-13
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• 2007

Hearing loss in newborns is the most frequently occurring birth defect. If hearing impaired children are not identified and managed early, it is difficult for many of them to acquire the fundamental language, social and cognitive skills that provide the foundation for later schooling and success in society. All newborns, both high and low risk, should be screened for hearing loss in the birth hospital prior discharge (Universal Newborn Heaing Screening, UNHS). Objective physiologic measures must be used to detect newborns and very young infants with hearing loss. Recent technological developments have produced screening methods and both evoked otoacoustic emission (EOAE) and auditory brainstem response (ABR) have been successfully implemented for UNHS. Audiologic evaluation should be carried out before 3 months of age and infants with confirmed hearing loss should receive intervention before 6 months of age. All infants who pass newborn hearing screening but who have risk indicators for other auditory disorders and/or speech and language delay receive ongoing audiologic surveillance and monitoring for communication development. Infants with sensorineural hearing loss are managed with hearing aids and receive auditory and speech-language rehabilitation therapies. Cochlear implants can be an outstanding option for certain children aged 12 months and older with severe to profound hearing loss who show limited benefit from conventional amplifications.

• International Journal of Fluid Machinery and Systems
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• v.10 no.2
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• pp.154-163
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• 2017

Performance characteristics in pump mode of pump-turbines are vital for the safe and effective operation of pumped storage power plants. However, the head characteristics are different under different guide vane openings. In this paper, 3-D steady simulations were performed under 13mm, 19mm and 25mm guide vane openings. Three groups of operating points under the three GVOs were chosen based on experimental validation to investigate the influence of guide vane setting on flow patterns upstream and downstream. The results reveal that, the guide vane setting will obviously change the flow pattern downstream, which in turn influences the flow upstream. It shows a strong effect on hydraulic loss (power dissipation) in the guide and stay vanes. It is also found that the hydraulic loss mainly comes from the flow separation and vortices. In addition, in some operating conditions, the change of guide vane opening will change the flow angle at the runner inlet and outlet, which will change the Euler momentum (power input). The joint action of Euler momentum and hydraulic loss results in the change of the head characteristics.

• Korean Journal of Head & Neck Oncology
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• v.27 no.1
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• pp.84-87
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• 2011

Branchio-otic syndrome(BOS) is a relatively uncommon genetic malformation associated with dysmorphogenesis of the first and second branchial arches and is characterized by branchial fistulae, congenital preauricular fistulae, and anomalies of the pinnae, external, middle, and inner ears, accompanied by hearing loss. Recently, we experienced a case of BOS in a 10 years old female patient and report this case with a review of literature. 10-year-old girl presented with hearing impairment, bilateral preauricular fistula and cervical fistula. The pure tone audiometry revealed that she had 60dB sensorineural hearing loss on right side and 90dB mixed hearing loss on left. Bilateral branchial fistula was found on the neck CT scan and bilateral ossicular and cochlear abnormality combined with enlarged internal auditory canal was noted on the temporal bone CT scan. To investigate the association with EYA1 gene, we performed DNA sequncing with peripheral white blood cell and found the point mutations on Exon 7, 12 and 16 of EYA1 gene. The preauricular fistula and branchial fistula was excised surgically and hearing aid was applied on her left side. There was no sign of fistula recurrence for seven years after the surgery.

• Journal of Biosystems Engineering
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• v.43 no.4
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• pp.296-302
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• 2018

Purpose: The aim of this study was to determine appropriate threshing and selection conditions for sorghum harvesting using a rice combine-harvester. Methods: Sorghum harvesting performance was tested using an actual rice combine. Through this test, the grain loss rate and the composition of crops according to the engine and fan speeds of the combine were investigated. Furthermore, the optimal threshing and selection conditions were determined by carrying out a harvest test based on the opening size factor of the concave in a test field. Results: The grain loss rate for the sorghum using a concave ($18{\times}18mm$) of the rice combine was the lowest at 0.1% at a chaffer angle of $40^{\circ}$, engine speed of 2000 rpm, and fan speed of 20 m/s, but the sorting sieve clogged frequently. Furthermore, as the engine speed and fan speed increased, the grain loss rate also increased. The sorghum harvesting test results of the combine according to the concave opening size showed that the grain loss rate was 0.5% at a driving speed of 0.5 m/s, with a concave opening diameter of 13 mm, a chaffer angle of $40^{\circ}$, a concave sieve oscillation frequency of 4.8 Hz, a fan speed of 20 m/s, and an engine speed of 2000 rpm. Conclusions: Findings showed that sorghum could be harvested using a head feeding rice combine.

• Journal of Audiology & Otology
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• v.24 no.4
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• pp.198-203
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• 2020

Background and Objectives: We sought to evaluate the diagnostic and prognostic value of measurable parameters of internal auditory canal (IAC) magnetic resonance imaging (MRI) in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Subjects and Methods: We retrospectively reviewed the patients with ISSNHL who underwent IAC MRI from January 2008 to March 2019. Measurable parameters of IAC MRI, such as the diameter of the IAC, bony cochlear nerve canal, and cross-sectional area of the cochlear nerve, were measured by a single examiner. These parameters were then compared between the affected and healthy sides. Inner-ear abnormalities such as intralabyrinthine hemorrhage or labyrinthitis were also evaluated. The relationship between the surveyed parameters and the diagnosis of ISSNHL was assessed. Results: A total of 208 patients with ISSNHL were included. The measured parameters of IAC MRI were not different between the affected and healthy sides and were also not associated with the diagnosis of ISSNHL. However, inner-ear abnormalities of IAC MRI in ISSNHL displayed a significant association with worse hearing before and after treatment. An age that was older than 40 years also correlated with poorer outcomes. Further, inner-ear abnormalities were more frequently detected when IAC MRI was performed early after ISSNHL onset. Conclusions: Patients with ISSNHL and inner ear abnormalities such as intralabyrinthine hemorrhage or labyrinthitis identified via IAC MRI may experience poorer hearing outcomes. To detect such abnormal findings, it is recommended to perform IAC MRI early after the onset of ISSNHL.

• Korean Journal of Audiology
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• v.24 no.4
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• pp.198-203
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• 2020

Background and Objectives: We sought to evaluate the diagnostic and prognostic value of measurable parameters of internal auditory canal (IAC) magnetic resonance imaging (MRI) in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Subjects and Methods: We retrospectively reviewed the patients with ISSNHL who underwent IAC MRI from January 2008 to March 2019. Measurable parameters of IAC MRI, such as the diameter of the IAC, bony cochlear nerve canal, and cross-sectional area of the cochlear nerve, were measured by a single examiner. These parameters were then compared between the affected and healthy sides. Inner-ear abnormalities such as intralabyrinthine hemorrhage or labyrinthitis were also evaluated. The relationship between the surveyed parameters and the diagnosis of ISSNHL was assessed. Results: A total of 208 patients with ISSNHL were included. The measured parameters of IAC MRI were not different between the affected and healthy sides and were also not associated with the diagnosis of ISSNHL. However, inner-ear abnormalities of IAC MRI in ISSNHL displayed a significant association with worse hearing before and after treatment. An age that was older than 40 years also correlated with poorer outcomes. Further, inner-ear abnormalities were more frequently detected when IAC MRI was performed early after ISSNHL onset. Conclusions: Patients with ISSNHL and inner ear abnormalities such as intralabyrinthine hemorrhage or labyrinthitis identified via IAC MRI may experience poorer hearing outcomes. To detect such abnormal findings, it is recommended to perform IAC MRI early after the onset of ISSNHL.

• Journal of Biosystems Engineering
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• v.15 no.4
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• pp.310-318
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• 1990

The amount of grain loss incurred during harvesting operation through the chaff-outlet of combine may not be negligible. To minimize this grain loss and optimize condition of combining, it may be necessary that the amout of chaff-outlet loss dependent on varying crop condition is to be estimated as exactly as possible. This study was thus intended to develop the monitor that could indicate the amount of grain lost through the chaff-outlet of combine during haravesting operation, and to find out driving and operating method of combine that could reduce chaff-outlet loss. In the study(1), the frequency distributions of each sound generated by the impact of kernels and chaff, the sound generated by the impact of the mixture of kernels and chaff, and vibration or noise created by the combine engine and other moving parts were investigated experimentally. Based on the results of frequency analyses, the loss monitor was developed which could measure the impact sound of paddy kernels that could be distinguished from those of other threshing products through chaff-outlet, and from vibration or noise created by the combine engine and other moving parts. Also in this study, detecting capability of monitor was tested by comparing the amount of grain lost through chaff-outlet with the amount of grain detected by the loss monitor, and changes in chaff-outlet grain loss on the increase of traveling speed, location of chaff-outlet loss control plate and variety of paddy rice were measured using the loss monitor. The monitor developed in this study efficiently measured the amount of grain lost through the chaff-outlet of combine. It was found that the chaff-outlet grain loss ratio was affected greatly by the variety of paddy rice, the location of chaff-outlet loss control plate and traveling speed of combine.

• Korean Journal of Head & Neck Oncology
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• v.18 no.2
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• pp.135-141
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• 2002

Backgrounds and Objectives: Metastasis is a complex multistep process that requires sequential interactions between the invasive cell and the extra-cellular matrix. Transforming growth factor-${\beta}1$ ($TGF-{\beta}1$) is a multifunctional regulator of cellular differentiation, motility and growth. Loss of sensitivity to the growth inhibitory effects by $TGF-{\beta}1$ plays important roles in neoplastic progression. The aim of this study was to investigate the role of $TGF-{\beta}1$ in the neoplastic invasion and metastasis through matrix metalloproteinase (MMP) of laryngeal cancer cell lines. Material and Methods: Two laryngeal cancer cell lines, SNU-899 and SNU-1076 were treated with recombinant $TGF-{\beta}1$, and the expression of MMP-2 and MMP-9 was immunohistochemically evaluated and gelatinase activity was studied by gelatin zymogram. Results: The cell growth inhibition was evident on 4th days after 1ng/ml and 10ng/ml $TGF-{\beta}1$ treatment. The expressions of MMP-2 and MMP-9, and their gelatinase activities were increased in dose-dependent manner. Conclusion: $TGF-{\beta}1$ treatment in laryngeal cancer cell lines induces the expression of MMP-2 and MMP-9, thus playing a role in the digestion of extracellular matrix gelatin.