• Title/Summary/Keyword: head and neck carcinoma

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Clinical Factors Associated with Recurrence of Nasopharyngeal Carcinoma (비인두암의 재발에 연관된 임상적 지표)

  • Ok, Sohea;Lee, Soo-Hyung;Hwang, Sunjin;Park, Min-Woo;Cho, Jae-Gu;Baek, Seung-Kuk;Kwon, Soon-Young;Jung, Kwang-Yoon;Woo, Jeong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.30 no.1
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    • pp.5-9
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    • 2014
  • Background and Objectives : The objective of this study was to investigate clinical factors associated with recurrence of nasopharyngeal carcinoma(NPC). Materials and Methods : We performed a retrospective review of 112 diagnosed as nasopharyngeal carcinoma, treated concurrent chemo-radiotherapy(CCRT) and had complete response from March 1, 1995, to March 31, 2012. Results : Of the recurrent NPC patients, patients received 2nd line chemotherapy had more recurrence within 2 years(p=0.010). Especially, patients received 2nd line chemotherapy longer than 4 months tend to have recurrence early(p=0.035). Other factors are not different between recurrent and non-recurrent NPC patients. Conclusion : The presence and the duration of 2nd line chemotherapy are associated with early recurrence.

A Case of Bilateral Tonsillar Cancer Discovered in Metastatic Carcinoma of Unknown Origin (원발미상의 경부 전이암에서 발견된 양측 편도암 1예)

  • Choi, Jeong-Seok;Lim, Jae-Yol;Han, Chang-Dok;Kim, Young-Mo
    • Korean Journal of Head & Neck Oncology
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    • v.28 no.1
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    • pp.16-18
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    • 2012
  • Ipsilateral tonsillectomy and panendoscopy-guided biopsy following imaging studies are considered a standard procedure in the search for a primary origin in patients with cervical metastatic carcinoma of unknown origin(MUO). However, many authors recommended bilateral tonsillectomy for the determination of the primary site of a MUO, because cervical metastasis may occur contralateral to tonsillar carcinoma. The authors attempted to address the clinical implications of using routine bilateral tonsillectomy to determine the primary site of MUOs based on a case report of cervical MUO that was finally diagnosed as a bilateral synchronous tonsillar carcinoma with cervical metastasis after a diagnostic work-up that included bilateral tonsillectomy.

A Case of Parotid Mucoepidermoid Carcinoma Recurring along the Mask Strap Line (마스크 끈자국을 따라 재발한 이하선 점액표피양암종 1예)

  • Chang Ho Whangbo;Jae Ho Yoo;Jeong Kyu Kim;Dong Won Lee
    • Korean Journal of Head & Neck Oncology
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    • v.40 no.1
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    • pp.27-31
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    • 2024
  • Mucoepidermoid carcinoma is one of the most common malignant tumors that occur in the salivary glands. While several cases of distant metastasis have been reported, instances of metastasis to the skin are rare. We present the case of a 72-year-old man diagnosed with parotid mucoepidermoid carcinoma who experienced temporary remission following surgical resection and adjuvant chemoradiotherapy. However, the carcinoma recurred along the skin at the periauricular area along the mask line. Given the current prevalence of COVID-19, the practice of wearing masks has become more widespread. This case report highlights the recurrence of mucoepidermoid carcinoma along the mask strap line, emphasizing the importance of distinguishing it from benign dermatological conditions.

A Case of Mucoepidermoid Carcinoma Presenting as a Retromolar Trigonal Mass (구후 삼각부 종물 양상의 점액표피암종 1예)

  • Kwak, Seul Gi;Kim, Choon Dong;Kim, Eun Ju;Kim, Seung Woo
    • Korean Journal of Head & Neck Oncology
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    • v.30 no.2
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    • pp.79-82
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    • 2014
  • Salivary gland tumors take possession of almost 5% in head and neck malignancies. Among these, mucoepidermoid carcinoma(MEC) is most common malignany in major salivary glands(12-29%) and the parotid gland is most predilection site. Intra-oral MEC has a tendency to various locations, and the predilection sites are palate, cheek, mandible, lip and tongue in order of frequency. A few cases of MEC are occurred in with retromolar trigone, oropharynx, and ectopic salivary gland. Recently, we experienced a-65-year old woman with retromolar trigonal mass, and she was finally diagnosed as MEC. We report it with review of literature.

A Case of Adenoid Cystic Carcinoma in Larynx (후두에 발생한 선양낭성암종 1예)

  • Tae, Kyung;Lee, Young-Seok;Kim, Hee-Ok;Lee, Yong-Seop
    • Korean Journal of Head & Neck Oncology
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    • v.24 no.1
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    • pp.76-79
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    • 2008
  • Adenoid cystic carcinoma(ACC) is one of the common malignant tumor of the major and minor salivary glands. ACC arising from the larynx is relatively rare(less than 1% of laryngeal malignant tumors) and only about eighty cases have been reported in the English literature. Definite diagnosis of these lesions is made only from a histological analysis, because findings and symptoms are non-specific. The diagnosis progresses very slowly, therefore it often presents at an advanced stage with regional and distant metastasis. Here, we present one case of ACC of the supraglottic region with a review of literature.

A Case of Primary Squamous Cell Carcinoma of The Thyroid Gland (갑상선에서 발생한 원발성 편평상피세포암 1예)

  • Kang, Sihyung;Park, Gi Cheol
    • Korean Journal of Head & Neck Oncology
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    • v.37 no.2
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    • pp.91-95
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    • 2021
  • Primary squamous cell carcinoma of thyroid is a very rare malignant tumor with poor prognosis. It is usually diagnosed as an advanced disease infiltrating adjacent organs, and characterized by aggressive clinical course with an average postoperative survival time of less than 1 year. Recently, we had a 79- year-old woman with a painful neck mass who was diagnosed as primary squamous cell carcinoma of thyroid gland. She underwent total thyroidectomy and selective neck dissection(level III, VI) with no further postoperative managements such as radiation therapy or chemotherapy; she died of poor general condition and pneumonia resulting from rapid progression of the lesion on the 38th day after surgery. We report this case with a review of relevant literatures.

Mucoepidermoid Carcinoma of the Soft Palate in a Child (소아에서 발생한 연구개 점액표피양 종양 1례)

  • Jung, Hoon;Eun, Young-Gyu;Kwon, Kee-Hwan
    • Korean Journal of Head & Neck Oncology
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    • v.24 no.2
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    • pp.207-210
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    • 2008
  • The purpose of this paper is to review our experience with mucoepidermoid carcinoma(MEC), a rare tumour in minor salivary glands, in a paediatric patients. 15-year-old boy was noted to have a irregular round mass appearing atthe soft palate just to the right of the mid-line. A computed tomographic(CT) scan showed a palatal mass limited to soft palate with no bony erosion. The lesion was curetted and debulked. Pathology was reported as an intermediate-grade mucoepidermoid carcinoma, and the patient was considered to radiation therapy institution for further treatment. To date, patients remain free of disease. Wide local excision is the treatment of choice for low to intermediate grade MEC of the minor salivary glands in paediatric patients.

Two Cases of Papillary Carcinoma Arising from Thyroglossal Duct Cyst (TGDC) (갑상설관낭종에서 기원한 유두상 암종 2례)

  • Jeong, Yong Jun;Yum, Gun Hwee;Kwon, Soon Young;Oh, Kyoung Ho
    • International journal of thyroidology
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    • v.11 no.2
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    • pp.189-193
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    • 2018
  • A thyroglossal duct cyst (TGDC) is the most common congenital anomaly of the neck. However, carcinoma arising from TGDC is extremely rare. We report 2 cases of TGDC carcinoma. In the first case, a 21-year-old male patient complained of an anterior cervical mass; computed tomography (CT) and sonography revealed cystic mass that was suspected to be a TGDC. Sistrunk operation was performed. Papillary carcinoma was confirmed in pathologic examination. Additionally, he underwent total thyroidectomy and central neck dissection. After radioactive iodine ablation (RAI) was performed. In the second case, a 28-year-old male patient visited our out-patient department complaining of submental mass. He had already been diagnosed TGDC carcinoma 13 years ago and had undergone Sistrunk operation and total thyroidectomy. Malignancy was confirmed using fine-needle aspiration; thus, lateral neck dissection was performed and following this, he underwent RAI. Till date, no evidence of recurrence has been observed in these patients.

A Case of Carcinoma with Sebaceous Differentiation arising in the Patient who was Treated with Parotid Gland Adenocarcinoma (이하선 샘암종의 재발로 오인된 지선암 1예)

  • Park, Sohl;Yun, Ju Hyun;Go, Yu Jin;Jung, Soo Yeon
    • Korean Journal of Head & Neck Oncology
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    • v.38 no.1
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    • pp.37-41
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    • 2022
  • Sebaceous carcinoma is extremely rare in the parotid gland. Recently, we experienced a case of carcinoma with sebaceous differentiation arising from the parotid gland in patient who was diagnosed as parotid adenoma carcinoma and underwent total parotidectomy. A 73-year-old male visited our department for the evaluation of 3-month history of infra-auricular mass combined with pain. Radiologic finding showed lobulated enhancing and solid mass with calcification in the right parotid gland. Initially, total parotidectomy with supraomohyoid neck dissection was performed. Pathological findings showed capsulated whitish mass with hemorrhage and cystic degeneration. Immunohistochemically, CK7, CK5/6, p63 were positive and CEA was negative. The intra-operative frozen section diagnosis was mucoepidermoid carcinoma. The permanent diagnosis was changed to adenocarcinoma, NOS(not otherwise specified). Fourteen months later, the newly developed mass was noticed on the operation bed. The mass was clinically diagnosed as recurred adenocarcinoma. Revision parotidectomy was performed and pathological findings revealed that the tumor was newly developed sebaceous carcinoma. We report a case of carcinoma with sebaceous differentiation in parotid gland with a review of literature.

A Case of Parotid Metastasis from Sebaceous Carcinoma of the Eyelids (이하선으로 전이된 안검의 피지샘 암종 1예)

  • Chae, Hee Sung;Yang, Hui Joon;Paik, Seung Won;Kim, Ji-Hoon
    • Korean Journal of Head & Neck Oncology
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    • v.36 no.2
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    • pp.21-25
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    • 2020
  • Sebaceous carcinoma is a relatively rare and aggressive malignant tumor. Periocular area (especially eyelid) is the most common lesion to occur, and the most common extraocular lesion is the parotid gland. Because the lesion also mimic other benign inflammatory diseases, this leads to delayed diagnosis or misdiagnosis. Here, we report a 58-year-old male patient who presented with a non-tender painless left parotid mass after wide excision of sebaceous carcinoma in the left eyelid two years ago. When he was diagnosed with sebaceous carcinoma of left eyelid, there was a small left parotid tumor on the computed tomography. But no further examination and treatment were performed. Two years later, physical examination revealed growing parotid tumor and multiple neck nodes on the left side. After radical parotidectomy and neck dissection, histological examination showed a sebaceous carcinoma and neck node metastasis. Considering the aggressiveness of sebaceous carcinoma, further evaluation for parotid glands should be considered when sebaceous carcinoma of the eyelid was discovered. Postoperative chemoradiotherapy was performed for disease control. Follow up after two years, and computed tomography showed no sign of recurrence.