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http://dx.doi.org/10.21593/kjhno/2022.38.1.37

A Case of Carcinoma with Sebaceous Differentiation arising in the Patient who was Treated with Parotid Gland Adenocarcinoma  

Park, Sohl (Department of Otorhinolaryngology-Head and Neck Surgery, Ewha Womans University, College of Medicine)
Yun, Ju Hyun (Department of Otorhinolaryngology-Head and Neck Surgery, Ewha Womans University, College of Medicine)
Go, Yu Jin (Department of Otorhinolaryngology-Head and Neck Surgery, Ewha Womans University, College of Medicine)
Jung, Soo Yeon (Department of Otorhinolaryngology-Head and Neck Surgery, Ewha Womans University, College of Medicine)
Publication Information
Korean Journal of Head & Neck Oncology / v.38, no.1, 2022 , pp. 37-41 More about this Journal
Abstract
Sebaceous carcinoma is extremely rare in the parotid gland. Recently, we experienced a case of carcinoma with sebaceous differentiation arising from the parotid gland in patient who was diagnosed as parotid adenoma carcinoma and underwent total parotidectomy. A 73-year-old male visited our department for the evaluation of 3-month history of infra-auricular mass combined with pain. Radiologic finding showed lobulated enhancing and solid mass with calcification in the right parotid gland. Initially, total parotidectomy with supraomohyoid neck dissection was performed. Pathological findings showed capsulated whitish mass with hemorrhage and cystic degeneration. Immunohistochemically, CK7, CK5/6, p63 were positive and CEA was negative. The intra-operative frozen section diagnosis was mucoepidermoid carcinoma. The permanent diagnosis was changed to adenocarcinoma, NOS(not otherwise specified). Fourteen months later, the newly developed mass was noticed on the operation bed. The mass was clinically diagnosed as recurred adenocarcinoma. Revision parotidectomy was performed and pathological findings revealed that the tumor was newly developed sebaceous carcinoma. We report a case of carcinoma with sebaceous differentiation in parotid gland with a review of literature.
Keywords
Sebaceous carcinoma; Adenocarcinoma; Parotid gland;
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1 Takada Y, Kawamoto K, Baba S, Takada T, Inoue T, Tomoda K. Sebaceous carcinoma of the parotid gland: A case report. Case Rep Oncol. 2015;8:106-112.   DOI
2 Altemani A, Vargas PA, Cardinali I, Aguiar SS, Lopes M, Soares AB, et al. Sebaceous carcinoma of the parotid gland in children: An immunohistochemical and ploidy study. Int J Oral Maxillofac Surg. 2008;37:433-440.   DOI
3 Cohn ML, Callender DL, El-Naggar AK. Sebaceous carcinoma ex-pleomorphic adenoma: A rare phenotypic occurrence. Ann Diagn Pathol. 2004;8:224-226.   DOI
4 Marnouche EA, Maghous A, Kadiri S, Berhili S, Touil A, Kettani F, et al. Sebaceous carcinoma of the parotid gland: A case report and review of the literature. J Med Case Rep. 2016;10:174.   DOI
5 Khmou M, Laadam K, Cherradi N. Parotid gland, an exceptional localization of sebaceous carcinoma: Case report. BMC Clin Pathol. 2016;16:10.   DOI