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Two Cases of Papillary Carcinoma Arising from Thyroglossal Duct Cyst (TGDC)

갑상설관낭종에서 기원한 유두상 암종 2례

  • Jeong, Yong Jun (Department of Otolaryngology-Head and Neck Surgery, Korea University Ansan Hospital) ;
  • Yum, Gun Hwee (Department of Otolaryngology-Head and Neck Surgery, Korea University Ansan Hospital) ;
  • Kwon, Soon Young (Department of Otolaryngology-Head and Neck Surgery, Korea University Ansan Hospital) ;
  • Oh, Kyoung Ho (Department of Otolaryngology-Head and Neck Surgery, Korea University Ansan Hospital)
  • 정용준 (고려대학교 안산병원 이비인후-두경부외과학교실) ;
  • 염건휘 (고려대학교 안산병원 이비인후-두경부외과학교실) ;
  • 권순영 (고려대학교 안산병원 이비인후-두경부외과학교실) ;
  • 오경호 (고려대학교 안산병원 이비인후-두경부외과학교실)
  • Received : 2018.11.09
  • Accepted : 2018.11.19
  • Published : 2018.11.30

Abstract

A thyroglossal duct cyst (TGDC) is the most common congenital anomaly of the neck. However, carcinoma arising from TGDC is extremely rare. We report 2 cases of TGDC carcinoma. In the first case, a 21-year-old male patient complained of an anterior cervical mass; computed tomography (CT) and sonography revealed cystic mass that was suspected to be a TGDC. Sistrunk operation was performed. Papillary carcinoma was confirmed in pathologic examination. Additionally, he underwent total thyroidectomy and central neck dissection. After radioactive iodine ablation (RAI) was performed. In the second case, a 28-year-old male patient visited our out-patient department complaining of submental mass. He had already been diagnosed TGDC carcinoma 13 years ago and had undergone Sistrunk operation and total thyroidectomy. Malignancy was confirmed using fine-needle aspiration; thus, lateral neck dissection was performed and following this, he underwent RAI. Till date, no evidence of recurrence has been observed in these patients.

Keywords

References

  1. Mazzaferri EL. Thyroid cancer in thyroglossal duct remnants: a diagnostic and therapeutic dilemma. Thyroid 2004;14(5):335-6. https://doi.org/10.1089/105072504774193140
  2. Wood CB, Bigcas JL, Alava I, Bischoff L, Langerman A, Kim Y. Papillary-type carcinoma of the thyroglossal duct cyst: the case for conservative management. Ann Otol Rhinol Laryngol 2018;127(10):710-6. https://doi.org/10.1177/0003489418791892
  3. Kim CH, Han DH, Kim JH, Rho YS. A case of papillary carcinoma in thyroglossal duct cyst with mandibular invasion. Korean J Otolaryngol-Head Neck Surg 2006;49(12):1217-9.
  4. LiVolsi VA, Perzin KH, Savetsky L. Carcinoma arising in median ectopic thyroid (including thyroglossal duct tissue). Cancer 1974;34(4):1303-15. https://doi.org/10.1002/1097-0142(197410)34:4<1303::AID-CNCR2820340442>3.0.CO;2-S
  5. Weiss SD, Orlich CC. Primary papillary carcinoma of a thyroglossal duct cyst: report of a case and literature review. Br J Surg 1991;78(1):87-9. https://doi.org/10.1002/bjs.1800780127
  6. Klubo-Gwiezdzinska J, Manes RP, Chia SH, Burman KD, Stathatos NA, Deeb ZE, et al. Clinical review: ectopic cervical thyroid carcinoma--review of the literature with illustrative case series. J Clin Endocrinol Metab 2011;96(9):2684-91. https://doi.org/10.1210/jc.2011-0611
  7. Patel SG, Escrig M, Shaha AR, Singh B, Shah JP. Management of well-differentiated thyroid carcinoma presenting within a thyroglossal duct cyst. J Surg Oncol 2002;79(3):134-9; discussion 40-1. https://doi.org/10.1002/jso.10059
  8. Rayess HM, Monk I, Svider PF, Gupta A, Raza SN, Lin HS. Thyroglossal duct cyst carcinoma: a systematic review of clinical features and outcomes. Otolaryngol Head Neck Surg 2017;156(5):794-802. https://doi.org/10.1177/0194599817696504
  9. Shemen L, Sherman CH, Yurovitsky A. Imaging characteristics and findings in thyroglossal duct cyst cancer and concurrent thyroid cancer. BMJ Case Rep 2016;2016.
  10. Iftikhar H, Ikram M, Rizwan Nathani K, Yar Muhammad A. Papillary thyroid carcinoma within thyroglossal duct cyst: case series and literature review. Int Arch Otorhinolaryngol 2018;22(3):253-5. https://doi.org/10.1055/s-0037-1606277