• Title/Summary/Keyword: hazard ratio

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Novel cystography parameter to predict early recovery from urinary continence after radical prostatectomy for prostate cancer: a retrospective study

  • Yeong Uk Kim
    • Journal of Yeungnam Medical Science
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    • v.40 no.3
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    • pp.252-258
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    • 2023
  • Background: The purpose of this study was to investigate whether postoperative cystography findings can predict early and longterm recovery from incontinence after radical prostatectomy (RP), compared with the other cystography parameters. Methods: I retrospectively reviewed 118 patients who underwent robot-assisted RP (RARP) for localized prostate cancer at single institution between January 2016 and April 2021. One hundred and seven patients were included in the study. Postoperative cystography was routinely performed 7 days after surgery. The bladder neck to pubic symphysis ratio, vesicourethral angle, and bladder neck anteroposterior length (BNAP) ratio (the bladder neck-posterior margin distances divided by the anteroposterior lengths) were evaluated. Continence was defined as cessation of pad use. The association between these variables and urinary incontinence was also analyzed. Results: The urinary incontinence recovery rates 1, 3, 6, and 12 months after RARP were 43.92%, 66.35%, 87.85%, and 97.19%, respectively. Multivariate logistic regression analysis demonstrated that a lower BNAP ratio and wider vesicourethral angle were significantly associated with continence restoration at 1, 3, and 6 months after surgery. In addition, in terms of days of pad usage, lower BNAP ratio, wider vesicourethral angle, and bladder neck preservation were significantly associated with recovery from urinary incontinence within 12 months as assessed by Cox proportional hazard analysis. Conclusion: This study demonstrated that vesicourethral angle and BNAP ratio were independent predictors of early recovery from post-prostatectomy incontinence. I suggest that both the sagittal and coronal views of postoperative cystography help anticipate early continence restoration after RARP.

Pathogens and Prognotic Factors for Early Onset Sepsis in Very Low Birth Weight Infants (극소 저체중 출생아에서 조기 패혈증의 원인균과 예후인자)

  • Kim, Yi-Sun;Kim, Jin-Kyu;Yoo, Hye-Soo;Ahn, So-Yoon;Seo, Hyun-Ju;Choi, Seo-Heui;Park, Soo-Kyung;Jung, Yu-Jin;Kim, Myo-Jing;Jeon, Ga-Won;Koo, Soo-Hyun;Lee, Kyung-Hoon;Chang, Yun-Sil;Park, Won-Soon
    • Neonatal Medicine
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    • v.16 no.2
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    • pp.163-171
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    • 2009
  • Purpose: This study was conducted to determine the incidence, causative pathogens, risk factors and mortality for early onset sepsis in the first three days in very low birth weight infants. Methods: The medical records of 1,124 very low birth weight infants admitted to the neonatal intensive care unit of Samsung Medical Center between November 1994 and December 2008 were retrospectively reviewed. The incidence, causative pathogens, risk factors, and mortality for early onset sepsis in the first 3 days of life in very low birth weight infants were evaluated. Results: Early onset sepsis, as confirmed by positive blood cultures, was present in 17 of 1,124 infants (1.5%). Sixty-four percent of the isolated pathogens were gram-positive bacteria and 35% of the isolated pathogens were gram-negative bacteria. The dominant pathogens of early onset sepsis included Staphylococcus aureus (23.5%), Esherichia coli (23.5%), and Enterococcus (17.6%). Vaginal delivery (adjusted odds ratio [OR], 3.7; 95% confidence interval [CI], 1.3-10.3; P=0.01) was associated with early onset sepsis. The overall mortality (adjusted hazard ratio, 3.0; 95% CI, 1.4-6.5; adjusted P=0.0039) and mortality within 72 hours of life (adjusted hazard ratio, 6.5; 95% CI, 2.2-18.9; adjusted P=0.0005) of infants with early onset sepsis were higher than that of uninfected infants. Conclusion: Early onset sepsis remains an uncommon, but potentially lethal problem among very low birth weight infants. Knowledge of the likely causative organisms and risk factors for early onset sepsis can aid in instituting prompt and appropriate therapy, in order to minimize mortality.

Analysis of Flood Characteristics at Confluence by Lateral Inflow (횡유입에 의한 합류부 홍수특성 분석)

  • Choi, Hung-Sik;Cho, Min-Suk;Park, Young-Seop
    • Journal of the Korean Society of Hazard Mitigation
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    • v.6 no.1 s.20
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    • pp.59-68
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    • 2006
  • Flow separation of recirculation zone by increasing of flow and change of its direction at confluence results in backwater due to conveyance reduction. The hydraulic characteristics of flow separation are analysed by experimental results of flow ratios of tributary and main streams and approaching angles. The boundary of flow separation by dimensionless length and width is defined by the streamline of zero and this definition agrees well to the existing investigation. Because flow separation doesn't appear in small flow ratio and approaching angle of $30^{\circ}$, the equation of flow separation with flow ratio and approaching angle is provided. In flow separation consideration and comparing with previous results, the existing equations of dimensionless length and width ratios by function of approaching angle, flow ratio, and downstream Froude number are modified and also contraction coefficient and shape factor are analysed. Dimensionless length and width ratios are proportional to the flow ratio and approaching angle. In analysis of water surface profiles, the backwater effects are proportional to the flow ratio and approaching angle and the magnitude at outside wall is greater than that of inside wall of main stream. The length, $X_l$ from the beginning of confluence to downstream of uniform flow, where the depth is equal to uniform depth, is characterized by width of stream, flow ratio, approaching angle, and contraction coefficient. The ratios between maximum water depth by backwater and minimum depth at separation are analysed.

An Experimental Study of Fatigue and Static Behavior for Composite Deck Member (복합재료 바닥판 부재의 정적 및 피로거동에 관한 실험적 연구)

  • Kim, Young-Chan;Park, Tai-Young;Kim, Doo-Hwan
    • 한국방재학회:학술대회논문집
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    • 2007.02a
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    • pp.479-482
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    • 2007
  • For making an application in construction parts of the composite material's complicated theory needs to accumulation of data by the help of study and experiment(demonstrate). Thus, this study is conducted research and analysis about the Influence of repeated loading cycles on Strength Ratio of the high quality material which is Carbon/Epoxy Composite Laminates through the test of tensile and fatigue Characteristics, based on it, construction engineers will can apply composite materials to construction technical without difficulty.

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Parametric Study on Seismic Performance of Internally Confined Hollow CFT Column (내부 구속 중공 CFT 교각의 내진성능에 대한 매개변수 연구)

  • Kim, Hyun-Jong;Yeom, Eung-Jun;Han, Taek-Hee;Kang, Young-Jong
    • 한국방재학회:학술대회논문집
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    • 2007.02a
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    • pp.144-147
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    • 2007
  • Internally Confined Hollow-Concrete Filled Tube(ICH-CFT) column which has two tubes on both side of concrete, inner tube and outer tube perform great seismic abilities, ductility and absorption of energy, by the tubes and the hollow part. So this study does qualitative analysis about seismic capacities depending on parameters - diameter of column, hollow ratio, thickness of tubes - by moment-curvature analysis.

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Analysis on the Hydraulic Effect due to Bridge and Culvert in the Stream (교량 및 암거의 수리영향 분석)

  • Lee, Jong-Seol;Chung, Jae-Hak;Kim, Soo-Jun;Lee, Ho-Yul
    • 한국방재학회:학술대회논문집
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    • 2007.02a
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    • pp.571-574
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    • 2007
  • The purpose of this research is to analyze sensitivities on hydraulic characteristic factors of bridge and culvert causing flood water level rising. With HEC-RAS and RMA2 models, analysis of backwater due to bridge and culvert in an ideal stream was carried out. The results of hydraulic modeling and sensitivity analysis indicated that the opening ratio and the Froude number were the most sensitive factors and other factors were not quite sensitive to flood water level rising.

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C-reactive protein/albumin ratio as prognostic score in oral squamous cell carcinoma

  • Park, Heung-Chul;Kim, Moon-Young;Kim, Chul-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.42 no.5
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    • pp.243-250
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    • 2016
  • Objectives: Many studies have examined histopathological factors and various prognostic scores related to inflammation to predict outcomes. Here, we examined the prognostic value of the C-reactive protein/albumin (CRP/alb) ratio in oral squamous cell carcinoma (OSCC). Materials and Methods: This retrospective study included 40 patients with OSCC. Using univariate and multivariate analyses, we focused on the correlation of the CRP/alb ratio with clinicopathological characteristics and with overall survival. We then compared five inflammation-based prognostic scores, CRP/alb ratio, modified Glasgow Prognostic Score (mGPS), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and prognostic nutritional index (PNI), based on receiver operating characteristic (ROC) curves. Results: The optimal cut-off value for the CRP/alb ratio was 0.085. The group with a high CRP/alb ratio had a high TNM clinical stage (P=0.002) and larger primary tumors (P=0.029), with statistically significant differences in lymph node metastasis and distant metastasis. In addition, when the CRP/alb ratio was high, multivariate analysis showed a lower survival rate (P=0.002; hazard ratio=6.078), and the ROC curve showed more outstanding discriminatory ability regarding overall survival compared to other inflammation-based prognostic scores. Conclusion: The CRP/alb ratio can be an independent prognostic factor when predicting prognosis in OSCC and has good prognostic ability.

Analysis of Soil Erosion Hazard Zone by R Factor Frequency (빈도별 R인자에 의한 토양침식 위험지역 분석)

  • Kim, Joo-Hun;Oh, Deuk-Keun
    • Journal of the Korean Association of Geographic Information Studies
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    • v.7 no.2
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    • pp.47-56
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    • 2004
  • The purpose of this study is to estimate soil loss amount according to the rainfall-runoff erosivity factor frequency and to analyze the hazard zone that has high possibilities of soil erosion in the watershed. RUSLE was used to analyze soil loss quantity. The study area is Gwanchon that is part of Seomjin river basin. To obtain the frequency rainfall-runoff erosivity factor, the daily maximum rainfall data for 39 years was used. The probability rainfall was calculated by using the Normal distribution, Log-normal distribution, Pearson type III distribution, Log-Pearson type III distribution and Extreme-I distribution. Log-Pearson type III was considered to be the most accurate of all, and used to estimate 24 hours probabilistic rainfall, and the rainfall-runoff erosivity factor by frequency was estimated by adapting the Huff distribution ratio. As a result of estimating soil erosion quantity, the average soil quantity shows 12.8 and $68.0ton/ha{\cdot}yr$, respectively from 2 years to 200 years frequency. The distribution of soil loss quantity within a watershed was classified into 4 classes, and the hazard zone that has high possibilities of soil erosion was analyzed on the basis of these 4 classes. The hazard zone represents class IV. The land use area of class IV shows $0.01-5.28km^2$, it ranges 0.02-9.06% of total farming area. Especially, in the case of a frequency of 200 years, the field area occupies 77.1% of total fanning area. Accordingly, it is considered that soil loss can be influenced by land cover and cultivation practices.

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Effects of Performance-related Pay on Gender Labor Productivity Differences (성과급제도가 성별 노동생산성에 미치는 효과)

  • Jung, Jin-Yong
    • Asia-Pacific Journal of Business
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    • v.11 no.3
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    • pp.185-198
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    • 2020
  • Purpose - The purpose of this study is to examine the effect of performance-related pay on gender labor productivity differences theoretically and empirically. Design/methodology/approach - This study analyzes the Principal-Agent model in which a firm employes many male and female workers under moral hazard, and uses large survey data from Survey of Business Activities of MDIS (MicroData Integrated Service) in Korea. The fixed-effect model is employed in order to analyze the data. Findings - The theoretical result is that, after performance-related pay is offered to workers, the effect of performance-related pay on gender productivity is determined by whether the female ratio within firm affects firm's performance(such as revenue and profit) per capita. The empirical result is that, before performance-related pay is provided for all workers, the firm's female ratio does not affect firm's revenue and profit per capita at all, but after it is offered, the female ratio positively affects firm's performance per capita. Research implications or Originality - Fixed pay does not bring about the difference between male and female productivity, but performance-related pay affects female productivity more positively than male productivity in Korean firms. It means that female workers are more sensitive to incentives than men in Korea.

Risk of Cancer Mortality according to the Metabolic Health Status and Degree of Obesity

  • Oh, Chang-Mo;Jun, Jae Kwan;Suh, Mina
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.10027-10031
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    • 2014
  • Background: We investigated the risk of cancer mortality according to obesity status and metabolic health status using sampled cohort data from the National Health Insurance system. Materials and Methods: Data on body mass index and fasting blood glucose in the sampled cohort database (n=363,881) were used to estimate risk of cancer mortality. Data were analyzed using a Cox proportional hazard model (Model 1 was adjusted for age, sex, systolic blood pressure, diastolic blood pressure, total cholesterol level and urinary protein; Model 2 was adjusted for Model 1 plus smoking status, alcohol intake and physical activity). Results: According to the obesity status, the mean hazard ratios were 0.82 [95% confidence interval (CI), 0.75-0.89] and 0.79 (95% CI, 0.72-0.85) for the overweight and obese groups, respectively, compared with the normal weight group. According to the metabolic health status, the mean hazard ratio was 1.26 (95% CI, 1.14-1.40) for the metabolically unhealthy group compared with the metabolically healthy group. The interaction between obesity status and metabolic health status on the risk of cancer mortality was not statistically significant (p=0.31). Conclusions: We found that the risk of cancer mortality decreased according to the obesity status and increased according to the metabolic health status. Given the rise in the rate of metabolic dysfunction, the mortality from cancer is also likely to rise. Treatment strategies targeting metabolic dysfunction may lead to reductions in the risk of death from cancer.