• Earthquakes and Structures
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• v.19 no.2
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• pp.79-90
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• 2020

4- and 8-storey reinforced-concrete frame buildings are analyzed under the suites of the near-fault pulse-like, and the corresponding spectrally equivalent far-fault ground-motion records. Seismic fragility curves for the slight, moderate, extensive, and complete damage states are developed, and the damage probability matrices, and the mean loss ratios corresponding to the Design Basis Earthquake and the Maximum Considered Earthquake hazard levels are compared, for the investigated buildings and sets of ground-motion records. It is observed that the spectrally equivalent far-fault ground-motion records result in comparable estimates of the fragility curve parameters, as that of the near-fault pulse-like ground-motion records. As a result, the derived damage probability matrices and mean loss ratios using two suites of ground-motion records differ only marginally (of the order of ~10%) for the investigated levels of seismic hazard, thus, implying the potential for application of the spectrally equivalent ground-motion records, for seismic fragility and risk assessment at the near-fault sites.

• Environmental Analysis Health and Toxicology
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• v.31
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• pp.11.1-11.6
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• 2016

Objectives A hazard assessment of di(2-ethylhexyl) phthalate (DEHP), a commonly used workplace chemical, was conducted in order to protect the occupational health of workers. A literature review, consisting of both domestic and international references, examined the chemical management system, working environment, level of exposure, and possible associated risks. This information may be utilized in the future to determine appropriate exposure levels in working environments. Methods Hazard assessment was performed using chemical hazard information obtained from international agencies, such as Organization for Economic Cooperation and Development-generated Screening Information Data Set and International Program on Chemical Safety. Information was obtained from surveys conducted by the Minister of Employment and Labor ("Survey on the work environment") and by the Ministry of Environment ("Survey on the circulation amount of chemicals"). Risk was determined according to exposure in workplaces and chemical hazard. Results In 229 workplaces over the country, 831 tons of DEHP have been used as plasticizers, insecticides, and ink solvent. Calculated 50% lethal dose values ranged from 14.2 to 50 g/kg, as determined via acute toxicity testing in rodents. Chronic carcinogenicity tests revealed cases of lung and liver degeneration, shrinkage of the testes, and liver cancer. The no-observed-adverse-effect level and the lowest-observed-adverse-effect level were determined to be 28.9 g/kg and 146.6 g/kg, respectively. The working environment assessment revealed the maximum exposure level to be $0.990mg/m^3$, as compared to the threshold exposure level of $5mg/m^3$. The relative risk of chronic toxicity and reproductive toxicity were 0.264 and 0.330, respectively, while the risk of carcinogenicity was 1.3, which is higher than the accepted safety value of one. Conclusions DEHP was identified as a carcinogen, and may be dangerous even at concentrations lower than the occupational exposure limit. Therefore, we suggest management of working environments, with exposure levels below $5mg/m^3$ and all workers utilizing local exhaust ventilation and respiratory protection when handling DEHP.

• Environmental Analysis Health and Toxicology
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• v.10 no.1_2
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• pp.37-46
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• 1995

The purpose of this research is to estimate a safe environmental level of human exposure to thresholding-acting toxicants in drinking water and recommend the acceptable levels and management plans for maintaining good quality of drinking water' and protecting health hazard. This research has been funded as a national project for three years from 1992 to 1995. This study(the second year, 1993-1994) was conducted to monitor 39 species of noncarcinogenic chemicals such as volatile organic compounds(VOCs), polynuclear aromatic hydrocarbens(PAHs), pesticides and heavy metals of drinking water at some area in six cities of Korea, and evaluate health risk due to these chemicals through four main steps (hazard identification, exposure assessment, dose-response assessment and risk characterization) of risk assessment in drinking water. In hazard identification, 39 species of non-carcinogenic chemicals were identified by the US EPA classification system. In the step of exposure assessment, sampling of tap water from the public water supply system had been conducted from 1993 to 1994, and 39 chemicals were analyzed. Inclose-response assessment for non-carcinogens, reference doses(RfD) and lifetime health advisories(HAs) of lifetime acceptable levels were calculated. In risk characterization of detected chemicals, the hazard quotients of noncarcinogens were less than one except those of manganese and iron in D city.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5D
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• pp.861-867
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• 2006

The objective of this study is to analyze the landslide hazard areas by combining LRA (Lgistic Regression Analysis) and AHP (Analytic Hierarchy Program) methods with Remote Sensing and GIS data in Anseong-si. In order to classify landslide hazard areas of seven levels, six topographic factors (slope, aspect, elevation, soil drain, soil depth, and land use) were used as input factors of LRA and AHP methods. As results, high-risk areas for landslide (1 and 2 levels) by LRA and AHP of its own were classified as 46.1% and 48.7%, respectively. A new method by applying weighting factors to the results of LRA and AHP was suggested. High-risk areas for landslide (1 and 2 levels) form the new method was classified as 58.9%.

• 대한예방의학회:학술대회논문집
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• 1994.02a
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• pp.651-657
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• 1994

To assess quantitatively the association between benzene exposure and leukemia, we examined the mortality rate of a cohort with occupational exposure to benzene. Cumulative exposure for each cohort member was estimated from historical air-sampling data and, when no sampling data existed, from interpolation on the basis of existing data. The overall standardized mortality ratio (a measure of relative risk multiplied by 100) for leukemia was 337 (95 percent confidence interval, 154 to 641), and that for multiple myeloma was 409 (95 percent confidence interval, 110 to 1047). With stratification according to levels of cumulative exposure, the standardized mortality ratios for leukemia increased from 109 to 322, 1186, and 6637 with increases in cumulative benzene exposure from less than 40 parts per million-years (ppm-years), to 40 to 199, 200 to 399, and 400 or more. respectively. A cumulative benzene exposure of 400 ppm years is equivalent to a mean annual exposure of 10 ppm over a 40-year working lifetime; 10 ppm is the currently enforceable standard in the United States for occupational exposure to benzene. To examine the shape of the exposure-response relation, we performed a conditional logistic-regression analysis, in which 10 controls were matched to each cohort member with leukemia. From this model, it can be calculated that protection from benzene induced leukemia would increase exponentially with any reduction in the permissible exposure limit.

• Journal of Food Hygiene and Safety
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• v.26 no.4
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• pp.315-321
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• 2011

This study was performed to investigate contamination levels of aflatoxins, the secondary metabolites produced by fungi Aspergillus flavus and A. parasiticus, in herbal medicine. Herbs is susceptible to these fungi infections through its growth harvest, transport and storage. This study determine the aflatoxin $B_1$, $B_2$, $G_1$ and $G_2$ levels by HPLC-florescence detector coupled with photochemical enhancement in 558 samples herbal medicine distributed in Korea and China. Also, We checked a transfer ratio of aflatoxins from raw herbal medicines to herbal medicine extract. Hot water extraction of herbal medicines was prepared by air pressure and high pressure condition. The analytical method for aflatoxins was validated in this method. In results recoveries of the analytical method were ranged from 67.4% to 96.2% and, limits of detection and quantitation for aflatoxins were $0.015{\sim}0.138\;{\mu}g/kg$ and $0.046{\sim}0.418\;{\mu}g/kg$, respectively. According to the results of monitoring on aflatoxins in herbal medicine, aflatoxins 1.7 ug/kg $B_1$ and 0.9 ug/kg $G_1$ were detected in only one sample of Strychni Ignatii Semen, and 0.8 ug/kg $G_1$ in Strychni Semen. About 13.6~51.3% of aflatoxins were transferred to hot water extract. Although the detected levels are under the permitted levels for aflatoxins in herbal medicine, these amounts should be considered in regard to overall daily exposure to mycotoxins.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.22 no.53
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• pp.79-88
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• 1999

This paper presents an integral model for product safety and product liability resulting from a defective product. The essence of the paper is the process of supply of manufacturing products which satisfy the product liability and the product safety in terms of consumers expectation levels. The main criteria of the product safety is the hazard level which involves in the severity and frequency. The proposed model shows the process to supply the manufactured products under the conditions that they are suitable in comparison of hazard level and safety level established by each company. If the product do not meet the safety level, this paper proposes that four different types of PL and PS countermeasures for the risk types are forward, respectively.

• Journal of the Korean Society for Railway
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• v.8 no.2
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• pp.170-175
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• 2005

This study presents a prediction of a failure rate in a safety required system that consists of a embedded control system, requiring a satisfaction of a quantitative safety requirement. International Standards are employed to achieve a regular procedures in the whole life cycle of a system, for the purpose of a prediction and a evaluation of a fault that might be able to be happened in a system. This International Standards uses SIL (Safety Integrity Level) to evaluate a safety level of a system. SIL is divided into 4 levels, from level 1 to level 4, and each level has functional failure rate and dangerous failure rate of a system. In this paper we describe the conventional method to predict the dangerous failure rate and propose a method using hazard analysis to predict the dangerous failure rate. The conventional method and the technique using hazard analysis to predict the dangerous failure rate are made a comparison through the control modules of the interlocking system in KTX. The proposed method verify better effectiveness for the prediction of the dangerous failure rate than that of the conventional method.

• Fire Science and Engineering
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• v.15 no.2
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• pp.20-30
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• 2001

The science and technology of seismic hazard mitigation are increasingly being shared among scientists and policy makers around the world. Administrative expertise is also being shared. While there is still tremendous unevenness in technical and administrative capacities and resources, a global community of emergency managers is developing and there is a globalization of expertise. Hazards are better understood, tools for risk assessment are improving, techniques for hazard mitigation are being perfected, and communities and states are implementing more comprehensive disaster preparedness, response, and recovery programs. Priorities are also emerging and hazard mitigation has emerged as the priority of choice in North America and Europe. An increasingly important component of hazard mitigation is resilience, in terms of increased capacities for disaster mitigation and recovery at the community and even individual levels. Each year, more is known about the locations and natures of seismic hazards, although there are still unknown and poorly understood fault lines and limited understanding of related disasters such as tsunamis and landslides. More is known about the impact of earthquakes on the built environment, although nature still provides surprises to confound man's best extorts to reduce risk. More is known about human nature and how people respond to uncertain risk and when confronted by certain catastrophe. However, despite the increased understanding of seismic phenomena and how to protect people and property, there is much that needs to be done to reduce the risk, particularly in major metropolitan areas.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.8
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• pp.1188-1196
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• 2016

This study evaluated the risk of Clostridium perfringens (C. perfringens) foodborne illness from natural and processed cheeses. Microbial risk assessment in this study was conducted according to four steps: hazard identification, hazard characterization, exposure assessment, and risk characterization. The hazard identification of C. perfringens on cheese was identified through literature, and dose response models were utilized for hazard characterization of the pathogen. For exposure assessment, the prevalence of C. perfringens, storage temperatures, storage time, and annual amounts of cheese consumption were surveyed. Eventually, a simulation model was developed using the collected data and the simulation result was used to estimate the probability of C. perfringens foodborne illness by cheese consumption with @RISK. C. perfringens was determined to be low risk on cheese based on hazard identification, and the exponential model ($r=1.82{\times}10^{-11}$) was deemed appropriate for hazard characterization. Annual amounts of natural and processed cheese consumption were $12.40{\pm}19.43g$ and $19.46{\pm}14.39g$, respectively. Since the contamination levels of C. perfringens on natural (0.30 Log CFU/g) and processed cheeses (0.45 Log CFU/g) were below the detection limit, the initial contamination levels of natural and processed cheeses were estimated by beta distribution (${\alpha}1=1$, ${\alpha}2=91$; ${\alpha}1=1$, ${\alpha}2=309$)${\times}$uniform distribution (a = 0, b = 2; a = 0, b = 2.8) to be -2.35 and -2.73 Log CFU/g, respectively. Moreover, no growth of C. perfringens was observed for exposure assessment to simulated conditions of distribution and storage. These data were used for risk characterization by a simulation model, and the mean values of the probability of C. perfringens foodborne illness by cheese consumption per person per day for natural and processed cheeses were $9.57{\times}10^{-14}$ and $3.58{\times}10^{-14}$, respectively. These results indicate that probability of C. perfringens foodborne illness by consumption cheese is low, and it can be used to establish microbial criteria for C. perfringens on natural and processed cheeses.