• Journal of Chest Surgery
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• 제18권4호
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• pp.692-699
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• 1985

Fifty cases of Open Heart Surgery due to congenital and acquired heart disease were done using the cardiopulmonary bypass in the Department of Thoracic and Cardiovascular surgery, Chosun University Hospital from November, 1980 to June, 1985. 1. The age of the congenital heart disease was from 7 to 29 years, the mean age was 14.5 years. In the acquired heart disease, the age was from 14 to 48 years, and the mean age was 22.3 years. The ratio of male to female was about 1.8:1. 2. The number of congenital cyanotic heart disease were 7 patients, congenital acyanotic heart disease were 17 patients and acquired valvular heart disease were 26 patients. All of the acquired heart disease was one or more valve disease. 3. Preoperative symptoms of the congenital heart disease were exertional dyspnea [cyanotic 100%, acyanotic 70.6%] and palpitation [cyanotic 28.6%, acyanotic 76.1%], and the acquired heart diseases were exertional dyspnea [92.3%], palpitation [34.1 %], and chest discomfort [30.8%]. 4. The method of the myocardial protection during the cardiopulmonary bypass were mild or moderate hypothermia, intermittent coronary perfusion of the cardioplegic solution, topical myocardial hypothermia with 4oC Hartmann`s solution. 5. In the cases of the valve replacement, postoperative oral anticoagulant therapy was started at oral intake of food using the warfarin and persantin, and the prothrombin time was maintained 30-50% of control value during 3-6 months for tissue valve replacement and permanently for metal valve replacement. 6. The postoperative complications were appeared in 24 cases and the complications were wound infection, occipital alopecia, hemorrhage etc. 7. The mortality after open heart surgery was 8 percents and the cause of death was low cardiac output syndrome, right heart failure, DIC, and Left ventricle rupture.

• 대한건축학회논문집:계획계
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• 제34권4호
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• pp.11-18
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• 2018

The beauty is like the bubble of beer, and behavior scholars have been regarded as worthless to study. As a result, the aesthetic in construction projects has resulted in underestimation or neglect. The fundamental cause of this result is that it is not easy to estimate the value of the aesthetic. The hedonic calculus by Bentham has a possibility to valuating the intangible or invisible goods. In this context, this study proposes a method to valuate architectural aesthetic based on the hedonic calculus by Bentham. As a precondition for suggesting the valuation method, this study defined the architectural aesthetic as the value of attraction that affects the value of the built environment. As the concept of beauty that conforms to the architectural aesthetic, it has established the concept of beauty as 'the phenomenon of combining the foreground and background of Hartmann'. In addition, the scope of the value measurement is defined as 'built environment' so as to include not only the building but also the surrounding environment. We have reinterpreted the seven dimension of the hedonic calculus proposed by Bentham and systematized the method of valuation of the architectural esthetic based on the seven dimension. The result of this study is meaningful in that it presents a new perspective and approach to architectural aesthetic. And it will be used as grounds for valuation and analytical approach to architectural aesthetic and will be used as a basis for expanding the field of study from aesthetic to value.

• 방사성폐기물학회지
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• 제20권1호
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• pp.43-63
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• 2022

The aim of this review is to communicate some essential knowledge of the underlying mechanism of the corrosion of structural containment alloys during molten salt reactor operation in the context of prospective online monitoring in future MSR installations. The formation of metal halide species and the progression of their concentration in the molten salt do reflect containment corrosion, tracing the depletion of alloying metals at the alloy salt interface will assure safe conditions during reactor operation. Even though the progress of alloying metal halides concentrations in the molten salt do strongly understate actual corrosion rates, their prospective 1^st order kinetics followed by near-linearly increase is attributed to homogeneous matrix corrosion. The service life of the structural containment alloy is derived from homogeneous matrix corrosion and near-surface void formation but less so from intergranular cracking (IGC) and pitting corrosion. Online monitoring of corrosion species is of particular interest for molten chloride systems since besides the expected formation of chromium chloride species CrCl₂ and CrCl₃, other metal chloride species such as FeCl₂, FeCl₃, MoCl₂, MnCl₂ and NiCl₂ will form, depending on the selected structural alloy. The metal chloride concentrations should follow, after an incubation period of about 10,000 hours, a linear projection with a positive slope and a steady increase of < 1 ppm per day. During the incubation period, metal concentration show 1^st order kinetics and increasing linearly with time^1/2. Ideally, a linear increase reflects homogeneous matrix corrosion, while a sharp increase in the metal chloride concentration could set a warning flag for potential material failure within the projected service life, e.g. as result of intergranular cracking or pitting corrosion. Continuous monitoring of metal chloride concentrations can therefore provide direct information about the mechanism of the ongoing corrosion scenario and offer valuable information for a timely warning of prospective material failure.

• 한국시뮬레이션학회논문지
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• 제31권3호
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• pp.11-21
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• 2022

국과연은 물자표적에 대한 취약성 해석 모델인 AVEAM-MT(ADD Vulnerability and Effectiveness Assessment Model for Materiel Target)를 개발하고 있다. 이 모델에는 성형작약제트와 표적 간 상호작용을 해석하기 위해 두 가지 방법이 적용되었다. 그중 한 방법은 표적 부품으로 침투를 신속하게 계산하기 위해 Fireman-Pugh 방법을 개량한 경험적 모델이다. 다른 하나는 Walker-Anderson 침투모델을 성형작약제트에 적용할 수 있도록 개량한 물리기반 모델인 ADD-TSC(ADD Tandem Shaped Charge)이다. 이 논문에서는 이 두 방법을 간략히 기술하고, 경험식 방법과 물리기반 모델의 잔류침투성능 예측 결과를 비교한다. 또한 물리기반 모델이 예측한 침투성능과 문헌에서 찾은 실험 결과를 비교한다. 비교 결과는 두 방법 모두 AVEAM-MT와 같은 짧은 시간에 상당한 양의 반복적인 피해해석 시뮬레이션 수행이 요구되는 취약성 해석 모델에 탑재되어 고속 계산 또는 상대적으로 높은 충실도 계산에 유용하게 사용될 수 있음을 보인다.

• Journal of Yeungnam Medical Science
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• 제40권2호
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• pp.164-171
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• 2023

Background: The study aimed to evaluate the effect of prehydration solution on hearing thresholds after cisplatin chemotherapy. Methods: In this retrospective cohort study, we reviewed the data of patients who underwent ≥3 courses of cisplatin-based chemotherapy for locally advanced head and neck cancers at a tertiary referral center (n=64). The dextrose solution (DW) group (n=26) received 2 L of normal saline and 1 L of 5% dextrose. The Hartmann solution (HS) group (n=38) received 2 L of normal saline and 1 L of HS. Hearing data were measured 1 day before starting the first course of chemotherapy, and again 20 days after the first, second, and third courses of chemotherapy. The severity of hearing loss was evaluated using the Common Terminology Criteria for Adverse Events (CTCAE). Results: Thresholds at all frequencies after chemotherapy were greater in the DW group than in the HS group. The increase in thresholds in 1 to 4 kHz after the third course of chemotherapy was greater in the DW group than in the HS group. CTCAE grades after the second and third courses of chemotherapy were greater in the DW group than in the HS group. Logistic regression showed that the odds ratio for CTCAE grade 3 or 4 after the third course of chemotherapy in the DW group was 4.84 on univariate analysis. Conclusion: Prehydration using a solution with salt was associated with a decrease in change in hearing thresholds after cisplatin chemotherapy in patients with head and neck cancers.

• 한국안전학회지
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• 제39권2호
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• pp.38-43
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• 2024

Recently, with the expanding market for electronic devices and electric vehicles, secondary battery usage has been on the rise. Lithium-ion batteries are particularly popular due to their fast charging times and lightweight nature compared to other types of batteries. A secondary battery consists of four components: anode, cathode, electrolyte, and separator. Generally, the positive and negative electrode materials of secondary batteries are composed of an active material, a binder, and a conductive material. Acetylene Black (AB) is utilized to enhance conductivity between active material particles or metal dust collectors, preventing the binder from acting as an insulator. However, when recycling waste batteries that have been subject to high usage, there is a risk of fire and explosion accidents, as accurately identifying the characteristics of Acetylene Black dust proves to be challenging. In this study, the lower explosion limit for Acetylene Black dust with an average particle size of 0.042 ㎛ was determined to be 153.64 mg/L using a Hartmann-type dust explosion device. Notably, the dust did not explode at values below 168 mg, rendering the lower explosion limit calculation unfeasible. Analysis of explosion delay times with varying electrode gaps revealed the shortest delay time at 3 mm, with a noticeable increase in delay times for gaps of 4 mm or greater. The findings offer fundamental data for fire and explosion prevention measures in Acetylene Black waste recycling processes via a predictive model for lower explosion limits and ignition delay time.

• International Journal of Stem Cells
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• 제16권3호
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• pp.293-303
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• 2023

Background and Objectives: The physiological oxygen tension in fetal brains (~3%, physioxia) is beneficial for the maintenance of neural stem cells (NSCs). Sensitivity to oxygen varies between NSCs from different fetal brain regions, with midbrain NSCs showing selective susceptibility. Data on Hif-1𝛼/Notch regulatory interactions as well as our observations that Hif-1𝛼 and oxygen affect midbrain NSCs survival and proliferation prompted our investigations on involvement of Notch signalling in physioxia-dependent midbrain NSCs performance. Methods and Results: Here we found that physioxia (3% O₂) compared to normoxia (21% O₂) increased proliferation, maintained stemness by suppression of spontaneous differentiation and supported cell cycle progression. Microarray and qRT-PCR analyses identified significant changes of Notch related genes in midbrain NSCs after long-term (13 days), but not after short-term physioxia (48 hours). Consistently, inhibition of Notch signalling with DAPT increased, but its stimulation with Dll4 decreased spontaneous differentiation into neurons solely under normoxic but not under physioxic conditions. Conclusions: Notch signalling does not influence the fate decision of midbrain NSCs cultured in vitro in physioxia, where other factors like Hif-1𝛼 might be involved. Our findings on how physioxia effects in midbrain NSCs are transduced by alternative signalling might, at least in part, explain their selective susceptibility to oxygen.

• Journal of Chest Surgery
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• 제4권2호
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• pp.69-80
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• 1971

Total body perfusion using Rygg-Kyvsgaard Heart-Lung-Machine, Mark IV, Polystan was attempted in the dogs by the hemodilution method with total prime of buffered Hartman's solution and under hypothermia. The first of all, the functions of Rygg--Kyvsgaard Heart-Lung-Machine and the effects of the hemodilution perfusion by buffered Hartman's solution was studied. At the same time the changes of blood pressure, oxygen consumption, and influence on the blood pictures were observed before, during, and in 1-3 days after perfusion. Hemodilution rates were the average 74. 22cc/Kg(the ranges of 67 to 81 cc/Kg) and perfusion flow rates were maintained in the mean 62. 6cc/Kg/min., Although it was possible to check up to 87 cc/ Kg/min. The total body perfusion continued for 60-80 minutes. Hypothermia was employed between $36^{\circ}C$ and $32^{\circ}C$ of the rectal temperature. Arterial pressure was ranged approximately between 68mmHg and 149mmHg, but generally, it was maintained over 80mmHg. Venous pressure was measured between 6.5cm $H_2O$and 11.5cm $H_2O$. Optimum oxygenation can be expected when oxygen flow into the disposable bubble oxygenator was maintained approximately at 3.5 L/min .. Inthis way, the oxygen contents were measured in the mean value of 13.11${\pm}$O.56 vol. % of arterial blood and 8.67+1.08 vol.% of venous blood(P${\pm}$0.86 vol.% in arteriovenous oxygen difference and 2. 97${\pm}$0.62cc/Kg in oxygen consumption were calculated. According to these dates, it is as plain as pikestaff that excellent oxygenation and good tissue perfusion was accomplished. Erythrocyte, hemoglobin and hematocrit were decreased about 38% during extracorporeal circulation and these were not recovered until 1-3 days after perfusion. These decrease was resulted from relatively high degree of hemodilution rate and no blood transfusion to compensate during these experimental studies. The platelets were also decreased about 76% during perfusion, but on the contrary, it was increased progressively after perfusion and in 1-3 days after perfusion was returned to the control level. Leucocyte were also decreased during perfusion, but it was increased progessively after perfusion and in 1-3 days after perfusion exceed the control level. This increase was resulted from postoperative infection of the wound, but its analysis were not changed significantly.

• Current Optics and Photonics
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• 제2권3호
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• pp.269-279
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• 2018

We are currently investigating the feasibility of a 1.6 m telescope with a laser-guide star adaptive optics (AO) system. The telescope, if successfully commissioned, would be the first dedicated adaptive optics observatory in South Korea. The 1.6 m telescope is an f/13.6 Cassegrain telescope with a focal length of 21.7 m. This paper first reviews atmospheric seeing conditions measured over a year in 2014~2015 at the Bohyun Observatory, South Korea, which corresponds to an area from 11.6 to 21.6 cm within 95% probability with regard to the Fried parameter of 880 nm at a telescope pupil plane. We then derive principal seeing conditions such as the Fried parameter and Greenwood frequency for eight astronomical spectral bands (V/R/I/J/H/K/L/M centered at 0.55, 0.64, 0.79, 1.22, 1.65, 2.20, 3.55, and $4.77{\mu}m$). Then we propose an AO system with a laser guide star for the 1.6 m telescope based on the seeing conditions. The proposed AO system consists of a fast tip/tilt secondary mirror, a $17{\times}17$ deformable mirror, a $16{\times}16$ Shack-Hartmann sensor, and a sodium laser guide star (589.2 nm). The high order AO system is close-looped with 2 KHz sampling frequency while the tip/tilt mirror is independently close-looped with 63 Hz sampling frequency. The AO system has three operational concepts: 1) bright target observation with its own wavefront sensing, 2) less bright star observation with wavefront sensing from another bright natural guide star (NGS), and 3) faint target observation with tip/tilt sensing from a bright natural guide star and wavefront sensing from a laser guide star. We name these three concepts 'None', 'NGS only', and 'LGS + NGS', respectively. Following a thorough investigation into the error sources of the AO system, we predict the root mean square (RMS) wavefront error of the system and its corresponding Strehl ratio over nine analysis cases over the worst ($2{\sigma}$) seeing conditions. From the analysis, we expect Strehl ratio >0.3 in most seeing conditions with guide stars.

• 한국토양비료학회지
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• 제18권2호
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• pp.121-127
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• 1985

토양수분(土壤水分)을 효율적(效率的)으로 관리(管理)할 수 있는 토양개량방법(土壤改良方法)을 구명(究明)하고 토양입단(土壤粒團)의 특성(特性)이 수분변화(水分變化)에 미치는 영향(影響)을 파악(把握)하여 토양구조개선(土壤構造改善)에 적정기준(適正基準)을 제시(提示)하기 위(爲)하여 사양토(砂壤土)와 식양토(埴壤土)에 친수성(親水性)인 Uresol과 소수성(疎水性)인 Bitumen을 처리(處理)하여 시험(試驗)을 실시(實施)하였다. Perspex관(管)을 세토(細土)로 채우고 개량제(改良劑)를 처리(處理)한 토양입단(土壤粒團)과 처리(處理)하지 않은 토양(土壤)을 2cm 두께로 복토(覆土)한 후(後), 인공강우하(人工降雨下)에서 수분(水分)의 침투량(浸透量)을 측정(測定)하고 인공기상조건(人工氣象條件)에서 r-선(線) 수분측정기(水分測定機)를 이용(利用)하여 수분(水分)의 증발량(蒸發量)을 조사(調査)하였다. 토양(土壤)의 수분침투량(水分浸透量)은 친수성(親水性) 토양개량제(土壤改良劑) Uresol 처리(處理)에 의하여 18.7~50.8% 증대(增大)되었으며 소수성(疎水性) Bitumen 처리(處理)는 25% 이하(以下)로 감소(減少)되었다. 증발량(蒸發量)은 Bitumen 처리(處理)로 22.0~68.1%로 억제(抑制)되었으며 Uresol 처리(處理)도 38.7~68.4%로 감소(減少)되었다. 수분침투(水分浸透)와 증발(蒸發)을 합(合)한 총수분이용율(總水分利用率)은 Uresol 처리(處理)에 의하여 2배(倍) 이상(以上) 높일 수 있었다. 토양입단(土壤粒團)의 안정성(安定性), 습윤각(濕潤角)등은 수분(水分)의 침투(浸透)와 증발(蒸發)에 영향(影響)을 끼쳤으며 특(特)히 수분침투(水分浸透)와 습윤각(濕潤角)-안정지수(安定指數), 수분증발(水分蒸發)과 습윤각(濕潤角)-불안정지수(不安定指數)와는 고도(高度)의 유의성(有意性)있는 대수함수적(對數函數的)인 정(正)의 상관(相關)이 있었다. 토양입단(土壤粒團)의 안정성(安定性)은 수분(水分)의 침투(浸透) 및 증발억제(蒸發抑制)와 정상관(正相關)이 있으나 습윤각(濕潤角)의 개선(改善)은 수분침투(水分浸透)와 증발(蒸發)을 모두 증대(增大)시키는 요인(要因)이 되므로 전체적(全體的)인 수분관리면(水分管理面)에서는 토양입단(土壤粒團)의 안정성(安定性)을 증대(增大) 시키는 것이 효율적(效率的)인 것으로 판단(判斷)되었다.