• ETRI Journal
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• v.42 no.3
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• pp.433-445
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• 2020

A denial-of-service (DoS) attack is a serious attack that targets web applications. According to Imperva, DoS attacks in the application layer comprise 60% of all the DoS attacks. Nowadays, attacks have grown into application- and business-layer attacks, and vulnerability-analysis tools are unable to detect business-layer vulnerabilities (logic-related vulnerabilities). This paper presents the business-layer dynamic application security tester (BLDAST) as a dynamic, black-box vulnerability-analysis approach to identify the business-logic vulnerabilities of a web application against DoS attacks. BLDAST evaluates the resiliency of web applications by detecting vulnerable business processes. The evaluation of six widely used web applications shows that BLDAST can detect the vulnerabilities with 100% accuracy. BLDAST detected 30 vulnerabilities in the selected web applications; more than half of the detected vulnerabilities were new and unknown. Furthermore, the precision of BLDAST for detecting the business processes is shown to be 94%, while the generated user navigation graph is improved by 62.8% because of the detection of similar web pages.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.2
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• pp.279-286
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• 2010

Livestock production in Vietnam is, as in most Asian countries, increasing rapidly and changing into specialized highly intensified operations. The volume of animal excreta generated exceeds the capacity of the operation land base and cannot be utilized efficiently. As a consequence, there is a loss of plant nutrients from livestock farms that causes environmental pollution. This study carried out a feed and excretion experiment measuring fecal characteristic, daily fecal production, daily nitrogen and phosphorous excretion from grower-finisher pigs fed prevalent rations in Vietnam. Furthermore, equations for assessing the excretion were tested, which can be used in farm models for optimal recycling of manure while focusing on reducing pollution. The results indicated that fecal production and nutrient excretion were affected by the different rations tested. This study showed that five selected equations for predicting excretion from grower-finisher pigs in Danish conditions can also be used with precision in Vietnamese pig farming systems. The equations have been proven valid and can, therefore, be used as a much needed tool for assessing fecal production and nitrogen in excreta on pig farms. The study also showed that about 12% of nitrogen excreted was emitted during housing. Waste water contains more than half of the nitrogen excreted, mainly in ammonium form which has a high potential for gaseous emission.

• Communications for Statistical Applications and Methods
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• v.16 no.6
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• pp.1037-1046
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• 2009

Copy number variations(CNVs) are known as one of the most important factors in susceptibility to genetic disorders because they affect expression levels of genes. In previous studies, pyrosequencing, mini-sequencing real-time polymerase chain reaction(PCR), invader assays and other techniques have been used to detect CNVs. However, the higher the copy number in a genome, the more difficult it is to resolve the copies, so a more accurate method for measuring CNVs and assigning genotype is needed. PCR followed by a quantitative oligonucleotide ligation assay(qOLA) was developed for quantifying CNVs. The aim of this study was to compare the two methods for detecting and quantifying the CNVs of duplicated gene: the published pyrosequencing assay(pyro_CNV) and the newly developed qOLA_CNV. The accuracy and precision of the assay were evaluated for porcine KIT, which was selected as a model locus. Overall, the root mean squares(RMSs) of bias and standard deviation of qOLA_CNV were 2.09 and 0.45, respectively. These values are less than half of those of pyro CNV.

• Biomolecules & Therapeutics
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• v.14 no.1
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• pp.40-44
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• 2006

Mirtazapine is an antidepressant agent with dual action on both the noradrenergic and serotonergic neurotransmitter systems. A simple high performance liquid chromatographic method has been developed and validated for the quantitative determination of mirtazapine in human plasma. A reversed-phase Cl8 column was used for the determination of mirtazapine with a mobile phase composed of 0.01M ammonium acetate solution (pH 4.2) and acetonitrile (75:25, v/v%) at a flow rate of 1.2 mL/min. Terazosin hydrochloride was used as an internal standard. The fluorescence detector was set at excitation and emission wavelengths of 290 and 350 nm, respectively. Intra- and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification of 3 ng/mL. Mirtazapine was stable in human plasma under various storage conditions. This method was used successfully for a pharmacokinetic study using plasma samples after oral administration of a single 30 mg dose as mirtazapine base to 8 healthy volunteers. The maximum plasma concentration of mirtazapine was $64.1{\pm}28.0ng/mL$ at 1.8 h, and the area under the curve and elimination half-life were calculated to be $674.1{\pm}218.5ng\;h/mL\;and\;23.4{\pm}3.8h$, respectively.

• Bulletin of the Korean Chemical Society
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• v.30 no.11
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• pp.2631-2636
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• 2009

JHL45, a novel immune modulator for anti-atopic dermatitis and allergic airway disease, was synthesized from decursin isolated from Angelica gigas. In order to conduct a pharmacokinetic study of JHL45, an analytical method, ideally one that uses a minimal amount of biological sample must first be validated. In this study, a HPLC-MS/MS method was developed and validated for the quantification of JHL45 and its major metabolite, (+)-decursinol, from 10 ${\mu}L$ of rat plasma. JHL45 was stable under the analysis conditions, and intra- and inter-day accuracies exceeded 90.06%, with a precision variability ${\leq}$ 13.16% for each analyte. The mean values for Cmax, AUC8h, half-life of JHL45 in rats after intravenous administration of 5 mg/kg JHL45 were 24.59 μg/mL, 10.02 ${\mu}g{\cdot}h/mL$, and 1.88 h, respectively. The validated method herein will be useful for further pharmacokinetic studies of JHL45, as well as in preclinical and clinical phases.

• Journal of the Korea Institute of Military Science and Technology
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• v.13 no.5
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• pp.717-724
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• 2010

The initial trajectory of a spheroid configuration bobbin for precision guidance has been investigated by analyzing its aerodynamic load and six-degree-of-freedom motion. The effects of changes in the spheroidal head configuration, flow angle and lateral center-of-gravity offset are numerically studied using the commercial software "FLUENT". A wind tunnel test is also conducted to validate the numerical scheme and to examine effect of the Reynolds number on the flow around the bobbin. It is shown that the size of the separation bubble formed on the surface decreases significantly when the Reynolds number is varied between 110,000 and 140,000. At a zero flow angle, an oblate spheroidal head shows relatively moderate rotation while a prolate spheroidal head shows rapid rotation. The bobbin with a spherical head shape has little effect on the flow direction; however, the oblate bobbin is sensitive to the flow angle. The roll motion of the bobbin is greatly influenced by the lateral center-of-gravity offset and maximum dispersion is observed at half of the radius.

• Nuclear Engineering and Technology
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• v.55 no.3
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• pp.1031-1035
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• 2023

Neutron is an indirectly ionizing particle without charge, which is normally measured by detecting reaction products. Neutron detection system based on measuring gadolinium-converted gamma-rays is a good way to monitor the neutron because the representative prompt gamma-rays of gadolinium have low energies (79, 89, 182, and 199 keV). Low energy gamma-rays and their high attenuation coefficient on materials allow the simple design of a detector easier to manufacture. Thus, we designed a cadmium zinc telluride detector to investigate feasibility of simultaneous detection of gamma-rays and neutrons by using the Monte-Carlo simulation, which was divided into two parts; first was gamma-detection part and second was gamma- and neutron-simultaneous detection part. Consequently, we confirmed that simultaneous detection of gamma-rays and neutrons could be feasible and valid, although further research is needed for adoption on real detection.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.12
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• pp.1285-1292
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• 2011

The characteristics of a semiconductor chiller system with EEV have been experimentally studied. Three experiments on temperature changes (increase and decrease), load variation, and control precision were conducted to investigate the operating characteristics of the semiconductor chiller. The power consumption was 8.9 kW during increase in temperature. The required time was 37.5 min for CH1 and 39.5 min for CH2. Moreover, the time required for falling temperature was 26.5 min. The control precision for partial load operation was relatively low compared to that of a full load operation. In addition, the CH2 equipped with a step motor showed better control precision. The power consumed by the chiller for process cooling water was 1.8 kW, which was one-half of that consumed during the refrigeration cycle. The objective of this study is to provide an optimal control guideline for the semiconductor chiller design.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.7C
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• pp.726-732
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• 2003

The paper proposes a motion estimation (ME) technique to reduce computational complexity. It is achieved by skipping ME process for macro-blocks decided to be in no need of the operation. Thus, it is called ME skipping technique(MEST). In general, the ME is composed of integer pixel precision ME (IME) followed by half pixel precision ME (HME). The MEST is performed just before an IME process and makes a decision on skipping the IME process according to a criterion based on ME errors of adjacent macro-blocks (MBs) already encoded. When the IME process for a MB is decided to be skipped, which is called ME skip mode, the IME process is skipped and the integer pixel precision motion vector of the MB is just replaced by a predicted vector and used as the input of HME. On the other hands, the IME processes for MBs in ME non-skip mode are not skipped but normally performed. Accordingly, the MEST is very effective to reduce computational complexity when MBs in ME skip mode is abundant. In addition, when the MEST is applied to video encoder, it contributes to more accurate rate control and more robusaess for channel errors. It is experimentally shown that the MEST has the above advantages while maintaining good reconstructed image quality.

• Journal of Korean Neurosurgical Society
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• v.64 no.1
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• pp.4-12
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• 2021

Spinal metastases can present with varying degrees of mechanical instability. The Spinal Instability Neoplastic Score (SINS) was developed as a tool to assess spinal neoplastic-related instability while helping to guide referrals among oncology specialists. Some previous papers suggested that the SINS was accurate and reliable, while others disagreed with this opinion. We performed a systematic review regarding the SINS to evaluate its accuracy and precision in predicting vertebral compression fractures (VCFs). The 21 included studies investigated a total of 2118 patients. Thirteen studies dealt with the accuracy of SINS to predict post-radiotherapy VCFs, and eight dealt with the precision. Among 13 studies, 11 agreed that the SINS categories showed statistically significant accuracy in predicting VCF. Among eight studies, body collapse was effective for predicting VCFs in six studies, and alignment and bone lesion in two studies. Location has no statistical significance in predicting VCFs in any of the eight studies. The precision of SINS categories was substantial to excellent in six of eight studies. Among the six components of the SINS, the majority of the included studies reported that location showed near perfect agreement; body collapse, alignment, and posterolateral involvement showed moderate agreement; and bone lesion showed fair agreement. Bone lesion showed significant accuracy in predicting VCFs in half of eight studies, but displayed fair reliability in five of seven studies. Although location was indicated as having near perfect reliability, the component showed no accuracy for predicting VCFs in any of the studies and deleting or modifying the item needs to be considered. The SINS system may be accurate and reliable in predicting the occurrence of post-radiotherapy VCFs for spinal metastasis. Some components seem to be substantially weak and need to be revised.