• 제목/요약/키워드: guide tube

검색결과 132건 처리시간 0.029초

Intracisternal Antidepressants Suppressed the Nociceptive Jaw Opening Reflex in Freely Moving Rats

  • Ahn, Dong-Kuk;Kim, Yun-Sook
    • The Korean Journal of Physiology and Pharmacology
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    • 제2권3호
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    • pp.307-312
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    • 1998
  • This study was performed to investigate the mechanism of central analgesic effects of antidepressants. Thirty four male rats were anesthetized with pentobarbital sodium (40 mg/kg, ip). A stainless steel guide cannula and a PE tube (PE10) were implanted into the lateral ventricle and cisterna magna area. Stimulating and recording electrodes were implanted into the incisor pulp and anterior digastric muscle. Electrodes were led subcutaneously to the miniature cranial connector sealed on the top of the skull with acrylic resin. The jaw opening reflex was used in freely moving rats, and antidepressants were administered intracisternally in order to eliminate the effects of anesthetic agents on the pain assessment and evaluate the importance of the central action site of antidepressants. After 48 hours of recovery from surgery, digastric electromyogram (dEMG) of freely moving rats was recorded. Electrical shocks (200 ${\mu}sec$ duration, 0.5-2 mA intensity) were delivered at 0.5 Hz to the dental pulp every 2 minute. Intracisternal administration of $15\;{\mu}g$ imipramine suppressed dEMG elicited by noxious electrical stimulation in the tooth pulp to $76{\pm}6%$ control. Intracisternal administration of $30\;{\mu}g$ desipramine, nortriptyline, or imipramine suppressed dEMG remarkably to $48{\pm}2,\;27{\pm}8,\;or\;25{\pm}5%$ of the control, respectively. Naloxone, methysergide, and phentolamine blocked the suppression of dEMG produced by intracisternal antidepressants from $23{\pm}2\;to\;69{\pm}4%,\;from\;32{\pm}5\;to\;80{\pm}9%,\;and\;from\;24{\pm}6\;to\;77{\pm}5%$ of the control, respectively. These results indicate that antidepressants produce antinociception through central mechanisms in the orofacial area. Antinociception of intracisternal antidepressants seems to be mediated by an augmentation of descending pain inhibitory influences on nociceptive pathways.

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X-ray microtomography를 이용한 치아의 3차원 재구성 (THREE DIMENSIONAL RECONSTRUCTION OF TEETH USING X-RAY MICROTOMOGRAPHY)

  • 신동훈
    • Restorative Dentistry and Endodontics
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    • 제28권6호
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    • pp.485-490
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    • 2003
  • Complete understanding of the exterior and interior structure of the tooth would be prerequisite to the successful clinical results, especially in the restorative and endodontic treatment. Although three-dimensional reconstruction method using x-ray microtomography could not be used in clinical cases, it may be the best way to reconstruct the morphologic characteristics of the tooth structure in detail without destructing the tooth itself. This study was done to three dimensionally reconstruct every teeth in the arch in order to increase the understanding about the endodontic treatment and to promote the effective restorative treatment by upgrading the knowledge of the tooth morphology. After placing tooth between the microfocus x-ray tube and the image intensifier to obtain two-dimensional images of each level. scanning was done under the condition of 80 keV, $100{\;}\mu\textrm{m}$, 16.8 magnification with the spot size of $8{\;}\mu\textrm{m}$. Cross-section pixel size of $16.28{\;}\mu\textrm{m}$ and 48.83 cross-section to cross-section distance were also used. From the results of this study, precise three dimensional reconstructed images of every teeth could be obtained. Furthermore, it was possible to see image that showed interested area only, for example. enamel portion only, pulp and dentin area without enamel structure, pulp only, combination image of enamel and pulp, etc. It was also possible to see transparent image without some part of tooth structure. This image might be used as a guide when restoring and preparing the full and partial crown by showing the positional and morphological relationship between the pulp and the outer tooth structure. Another profit may be related with the fact that it would promote the understanding of the interior structure by making observation of the auto-rotating image of AVI file from the various direction possible.

Simulation of a neutron imaging detector prototype based on SiPM array readout

  • Mengjiao Tang;Lianjun Zhang;Bin Tang;Gaokui He;Chang Huang;Jiangbin Zhao;Yang Liu
    • Nuclear Engineering and Technology
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    • 제55권9호
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    • pp.3133-3139
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    • 2023
  • Neutron imaging technology as a means of non-destructive detection of materials is complementary to X-ray imaging. Silicon photomultiplier (SiPM), a new type of optical readout device, has overcome some shortcomings of traditional photomultiplier tube (PMT), such as high-power consumption, large volume, high price, uneven gain response, and inability to work in strong magnetic fields. Its application in the field of neutron detection will be an irresistible general trend. In this paper, a thermal neutron imaging detector based on 6LiF/ZnS scintillation screen and SiPM array readout was developed. The design of the detector geometry was optimized by geant4 Monte Carlo simulation software. The optimized detector was evaluated with a step wedge sample. The results show that the detector prototype with a 48 mm × 48 mm sensitive area can achieve about 38% detection efficiency and 0.26 mm position resolution when using a 300 ㎛ thick 6LiF/ZnS scintillation screen and a 2 mm thick Bk7 optical guide coupled with SiPM array, and has good neutron imaging capability. It provides effective data support for developing high-performance imaging detectors applied to the China Spallation Neutron Source (CSNS).

40 W급 고출력 MMIC 개발과 고출력 증폭기 모듈 결합을 통한 Ku 밴드 반도체형 송신기(SSPA) 개발에 관한 연구 (Study on the Ku band Solid-State Power Amplifier(SSPA) through the 40 W-grade High Power MMIC Development and the Combination of High Power Modules)

  • 나경일;박재웅;이영완;김혁;강현철;김소수
    • 한국군사과학기술학회지
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    • 제26권3호
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    • pp.227-233
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    • 2023
  • In this paper, to substitute the existing TWTA(Travailing Wave Tube Amplifier) component in small radar system, we developed the Ku band SSPA(Solid-State Power Amplifier) based on the fabrication of power MMIC (Monolithic Microwave Integrated Circuit) chips. For the development of the 500 W SSPA, the 40 W-grade power MMIC was designed by ADS(Advanced Design System) at Keysight company with UMS GH015 library, and was processed by UMS foundry service. And 70 W main power modules were achieved the 2-way T-junction combiner method by using the 40 W-grade power MMICs. Finally, the 500 W SSPA was fabricated by the wave guide type power divider between the drive power amplifier and power modules, and power combiner with same type between power modules and output port. The electrical properties of this SSPA had 504 W output power, -58.11 dBc spurious, 1.74 °/us phase variation, and -143 dBm/Hz noise level.

Investigating the load-displacement restorative force model for steel slag self-stressing concrete-filled circular steel tubular columns

  • Feng Yu;Bo Xu;Chi Yao;Alei Dong;Yuan Fang
    • Steel and Composite Structures
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    • 제49권6호
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    • pp.615-631
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    • 2023
  • To investigate the seismic behavior of steel slag self-stressing concrete-filled circular steel tubular (SSSCFCST) columns, 14 specimens were designed, namely, 10 SSSCFCST columns and four ordinary steel slag (SS) concrete (SSC)-filled circular steel tubular (SSCFCST) columns. Comparative tests were conducted under low reversed cyclic loading considering various parameters, such as the axial compression ratio, diameter-thickness ratio, shear-span ratio, and expansion ratio of SSC. The failure process of the specimens was observed, and hysteretic and skeleton curves were obtained. Next, the influence of these parameters on the hysteretic behavior of the SSSCFCST columns was analyzed. The self stress of SS considerably increased the bearing capacity and ductility of the specimens. Results indicated that specimens with a shear-span ratio of 1.83 exhibited compression bending failure, whereas those with shear-span ratios of 0.91 or 1.37 exhibited drum-shaped cracking failure. However, shear-bond failure occurred in the nonloading direction. The stiffness of the falling section of the specimens decreased with increasing shear-span ratio. The hysteretic curves exhibited a weak pinch phenomenon, and their shapes evolved from a full shuttle shape to a bow shape during loading. The skeleton curves of the specimens were nearly complete, progressing through elastic, elastoplastic, and plastic stages. Based on the experimental study and considering the effects of the SSC expansion rate, shear-span ratio, diameter-thickness ratio, and axial compression ratio on the seismic behavior, a peak displacement coefficient of 0.91 was introduced through regression analysis. A simplified method for calculating load-displacement skeleton curves was proposed and loading and unloading rules for SSSCFCST columns were provided. The load-displacement restorative force model of the specimens was established. These findings can serve as a guide for further research and practical application of SSSCFCST columns.

로컬 청년창업 프로젝트 활성화 사례연구 (Case Study on Activating Local Youth Entrepreneurship Project)

  • 홍지영;남건욱;문예령;손가은;이한진
    • 문화기술의 융합
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    • 제10권5호
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    • pp.143-151
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    • 2024
  • 본 연구는 지역자원 기반 창업 프로젝트를 활성화하기 위해 프로그램 기획, 협의, 홍보, 모집, 운영, 지원, 성과측정의 일련 과정을 분석하여 가이드를 제안하고자 한다. 로컬브랜드에 관심이 높은 예비창업가들에게 어떤 방법과 내용으로 접근하는 것이 효과적인지 대해 실증적인 사례연구로서 가치를 전달할 것이다. 유튜브, 인스타그램, 포털 등 로컬창업 관심 커뮤니티 100곳을 선정 후 주제별로 분류한 뒤, 각 채널별 적합한 메시지 특성을 도출했다. 원본을 포함해 총 7개의 유형별로 메시지를 작성 및 배포 후 관심도에 따른 전환율을 측정했다. 4주 간 약 57,000회 이상의 조회, 13% 전환율, 100여 명의 지원자를 모집하였는데, 어떤 메시지 유형별로 반응이 높았는지 정성적, 정량적 평가를 할 수 있었다. 이러한 성과를 기반으로 초기 창업가의 인식과 창업생태계 지형도 파악뿐만 아니라 주요 정책적 시사점을 도출했다. 아울러 지역사회와 중간지원조직, 지역혁신센터와의 협력이 창업성공의 중요한 요소라는 점도 더했다.

비파괴검사 분야에서 방사선원의 위치 확인을 위한 반도체 검출기 설계에 관한 연구 (The Study on Design of Semiconductor Detector for Checking the Position of a Radioactive Source in an NDT)

  • 김교태;김주희;한무재;허예지;안기정;박성광
    • 한국방사선학회논문지
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    • 제11권3호
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    • pp.171-175
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    • 2017
  • 비파괴검사 분야에서는 작업자들의 안전을 확보하기 위해 방사선원에 대한 시스템 개발에 많은 시간과 재원을 투자하고 있으나 아직까지 사고 발생 확률은 높은 실정이다. 방사선에 대한 잠재적 사고를 미연에 방지하기 위해서는 방사선원의 위치를 직접적으로 검증하는 것이지만 아직까지 연구가 미흡한 실정이다. 이에 본 연구에서는 감마선조사기의 선원 가이드 튜브에서 방사선원의 위치를 감지할 수 있는 모니터링 시스템 개발을 위한 선행연구로써 몬테카를로 시뮬레이션을 통해 방사선 검출기에 대한 특성을 모의 추정하였다. 연구 결과, Ir-192의 감마선 에너지에 대한 방사선 검출기는 반도체 소재에 무관하게 $150{\mu}m$에서 2차 전자평형이 이루어지는 것으로 분석되었으며, 감마선 응답 특성은 $HgI_2$가 가장 우수할 것으로 기대된다. 이러한 결과는 차후 모니터링 시스템의 검출부에 위치하는 방사선 검출기의 최적화 두께를 결정하는데 기초자료로써 활용될 수 있을 것으로 기대되며, 이를 바탕으로 모니터링 시스템을 개발 시 방사선작업종사자가 위험을 쉽게 인지하여 안전을 확보할 수 있을 뿐만 아니라 잠재적인 방사선 사고에 대한 예방 및 선제적 대응이 가능함으로써 사회 안전망 구축 에 기여할 수 있을 것이다.

SMART 연구로 노외계측기 설계를 위한 IST 영역의 중성자속 분포 평가 (Evaluation of Neutron Flux Distributions of SMART-P IST Region for the Design of Ex-Core Detector)

  • 구본승;김교윤;이정찬;지성균
    • Journal of Radiation Protection and Research
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    • 제30권2호
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    • pp.55-60
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    • 2005
  • SMART 연구로의 노외계측기 설계를 위하여 고온 전출력 조건과 중성자 계수율이 최소가 되는 조건에 대해서 중성자속 분포 평가를 수행하였다. 고온 전출력 조건에서 IST 영역의 에너지 구간별 중성자속 분포 계산은 DORT와 MCNP코드를 이용하였으며, 계산 결과 IST 내의 첫 번째 물 영역에서 최대의 열중성자속을 보였고 두 코드 결과는 대략 10% 이내에서 일치하는 것으로 나타났다. 그리고 중성자 계수율이 최소가 되는 조건에서 노외계측기 설치 영역에서의 중성자속을 계산한 결과, 선원의 세기가 $1.0{\times}10^8(n/sec)$이라고 가정한 경우 최대 열중성자속의 크기는 $6.99{\times}10^{-2}(n/cm^2-sec)$로 전체 중성자속의 80% 이상을 차지하는 것으로 나타났는데 이는 IST 철 구조물을 통과한 속중성자가 감속능이 큰 물 영역에서 에너지를 잃고 열중성자로 변하였기 때문이다. 그러므로 노외계측기 설계시 계측기를 둘러싸는 계측기 안내관 충전물질, 설치위치 그리고 각 계측기 Segment들의 길이 등을 최적화하여 중성자 계수율을 증가시키는 방안을 모색할 필요가 있겠으며, 이러한 중성자속 평가 결과는 노외계측기가 IST 영역에 설치될 경우 노외계측기 선속 요건으로 이용될 수 있다.

태권도(跆拳道)에 대한 기공학적(氣功學的) 접근(接近) (A Study on the Relations between Gi-gong and Taekwondo)

  • 이명찬;사희수
    • 대한한의정보학회지
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    • 제14권1호
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    • pp.55-61
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    • 2008
  • The Taekwondo is the martial arts where possibility thousand Ul of history and the ancestor is put in with specific martial arts of our nation. Also it practiced with the self defense martial arts which rules over the body and a mind and it came, the country from crisis of imminent danger won a victory with the good state affair alcoholic beverage and it was come. The ancestors condition anger the Taekwondo where the soul is put in were born again with martial arts of the world and they became and the world-wide conference was adopted with the Olympic formal item which becomes the historian of of course sports and became the martial arts in the world-wide center. In like this features martial arts even from each country condition anger and the sports raises the phase of the country is racing with of course martial arts. Specially from China it makes the right shoe which is a Chinese martial arts with condition item and sports anger the features of the martial arts origination to do and there is a possibility of seeing the features which in the succession nose sleeping martial arts perforation defends it concentrates. The martial arts perforation character is letting in religion and philosophy thought of the Orient. Confucianism and Buddhism, it puts in the teaching of friendship thoughts and heaven and earth positive and negative principles, five lines and eight divination signs. Features of like this perforation our ancestors the positive and negative principles where the philosophy of the Orient is put in, there is a possibility of searching from life and the Taekwondo which it does with at five events together. With history of the ancestor it breathes together and all Taekwondo operation every one by one it puts in the thought of our ancestors as well. The some branch it tried to listen to the representative example which the feather holds hereupon in basic operation, the Taoist garment, the belt and width tax of Taekwondo. The flesh which is healthy in the spirit which is healthy holds the feather. Taekwondo Oh! as the true feelings one martial art which accomplishes the artificial flower of the dynamic thing and the static thing at end with the perforation essentially it is deep it will be able to confirm repeatedly fire tube characteristic.

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슬러리월의 내진설계를 위한 강재각관과 확대머리 철근으로 구성된 기계적 이음의 시공성 평가 (Constructability Evaluation of Seismic Mechanical Splice for Slurry Wall Joint Consisting of Steel Tube and Headed Bars)

  • 박순전;김대영;임인식
    • 한국건축시공학회지
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    • 제23권3호
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    • pp.295-303
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    • 2023
  • 최근 지진 발생의 빈도가 점진적으로 높아지고 있고 기초가 놓이는 지반의 특성 및 지층별 특성에 따른 지진 토압 연구결과가 활발해짐에 따라 지하구조물의 안전성 확보를 위한 내진설계가 의무화 되었다. 특히 초고층 건축물에서는 지상 구조물에 작용하는 횡력이 상대적으로 크므로 지하외벽의 역할이 기존의 토압에 대한 면외저항 외에도 지진하중, 지진토압, 정적토압에 의한 면내 방향의 전단벽 역할이 필수적이다. 슬러리월 공법은 벽체의 강성이 높아 다른 공법에 비해 안전하고 차수성이 우수하며 소음과 진동이 작기 때문에 도심지 대규모 초고층 현장 흙막이 공사에 자주 사용되고 있다. 하지만 슬러리월은 각기 패널로 분리되어 있어 면내 방향에 대해서는 벽체의 일체성이 확보되지 않는 구조형식이다. 그러한 기존의 슬러리월 공법을 이용하여 개개 패널로 전단력에 저항하면 슬러리월 단면이 지나치게 커지게 된다. 따라서 슬러리월 패널 간 일체성을 확보할 수 있는 전단보강 방법이 필요하며 이에 1차 패널과 2차 패널로 형성되는 슬러리월 시공절차를 고려하여 일부가 개방된 강재각관과 확대머리 철근으로 구성된 기계적 이음 방법을 개발하였다. 본 연구에서는 개발된 이음방법의 각 부위가 설계한 내력을 효과적으로 발휘할 수 있는지 그 타당성 및 시공성을 검증하기 위하여 현장 목업 실험을 실시하고 기존 유사공법들이 가지고 있는 단점을 얼마나 보완하며, 어떤 강점을 가지고 있는지도 또한 기술하고자 한다. 또 현장 목업 실험을 통해 도출된 여러 문제점을 지적하고 향후 문제점을 수정하여 더 나은 이음방법으로 발전하고자 연구를 진행하였다.