• Title/Summary/Keyword: growth-line

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Aloe 세포 배양계에서 $CO_2,\;O_2,\;C_2H_4$ gas가 세포 생장 및 다당체 생산에 미치는 영향

  • Park, Tae-Yeong;Jo, Gyu-Heon;Heo, Won;Kim, Dong-Il
    • 한국생물공학회:학술대회논문집
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    • 2000.04a
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    • pp.325-327
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    • 2000
  • We developed a on-line gas control system for three gas components and investigated the effect of oxygen, carbon dioxide, and ethylene on polysaccharide production and cell growth in the suspension cultures of Aloe saponaria. Carbon dioxide(5% v/v) enhanced significantly polysaccharide production while the cell growth was not affected.

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Characteristics of Raman scattering spectroscopy for $ZnS_{1-x}Te_x$ alloy semi- conductor ($ZnS_{1-x}Te_x$ 삼원 화합물 반도체의 라만 산란 특성)

    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.12 no.5
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    • pp.223-228
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    • 2002
  • We have studied the characteristics of Raman scattering spectroscopy from $_ZnS{1-x}Te_x$ alloys in the whole range of Te composition x. The Raman spectra showed two-mode behaviors for those alloys. The Raman line shape showed the changes of an asymmetry and broadening of that with Te composition x. The asymmetric broadening of the line shape could be explained with a spatial correlation model.

Growth and Telomerase Inhibition of SK-MEL 28 Melanoma Cell Line by a Plant Flavonoid, Apigenin

  • Kang, Sang-Sun;Lim, Seung-Eun
    • BMB Reports
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    • v.31 no.4
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    • pp.339-344
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    • 1998
  • The plant flavonoids, including apigenin which is found in especially high concentrations in edible plants, are reported to protect against chronic diseases including several types of cancer. We observed that apigenin inhibited not only the growth of human melanoma cell line SK-MEL 28 but also the telomerase activity. We also noted the telomerase activity inhibition by genistein, a tyrosine kinase inhibitor found in soybean, which suggests that the telomerase activity of SK-MEL 28 cells may be regulated by the protein phosphorylation. Furthermore, we observed that apigenin induced SK-MEL 28 cell apoptosis with p53 upregulation. Taken together, our results indicate that apigenin plays a role as an antimelanoma component in edible plants.

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Non-invasive Methods for Determination of Cellular Growth in Podophyllum hexandrum Suspension Cultures

  • Chattopadhyay, Saurabh;Bisaria, V.S.;Scheper, T.;Srivastava, A.K.
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.7 no.6
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    • pp.331-334
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    • 2002
  • Culture conductivity and on-line NADH fluorescence were used to measure cellular growth in plant cell suspension cultures of Podophyllum hexandrum. An inverse correlation between dry cell weight and medium conductivity was observed during shake flask cultivation. A linear relationship between dry cell weight and culture NADH fluorescence was obtained during the exponential phase of batch cultivation In a bioreactor under the pH stat (pH 6) conditions. It was observed that conductivity measurement were suitable for biomass characterisation under highly dynamic uncontrolled shake flask cultivation conditions. However, if the acid/alkali feeding is done for pH control the conductivity measurement could not be applied. On the other hand the NADH fluorescence measurement allowed online-in situ biomass monitoring of rather heterogenous plant cell suspension cultures in bioreactor even under the most desirable pH stat conditions.

US Aid and Taiwan

  • Lee, Wei-Chen;Chang, I-Min
    • Asian review of World Histories
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    • v.2 no.1
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    • pp.47-80
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    • 2014
  • After the outbreak of the Korean War on June 25, 1950, the US included the Republic of China on Taiwan (Taiwan hereafter) in its Asia-Pacific containment line, and restored the military and economic aid to Taiwan for the sake of regional security. The US aid to the countries along the Asia-Pacific defense line was not only in the form of supplying munitions, but also linked these countries together in an economic dimension. Taiwan is one of the 120 countries which had accepted US aid and also successfully moved from "dependence" to "independently sustained growth." This article will firstly review the historical background of US aid to Taiwan and related institutional development; secondly, this article will illustrate how Taiwan used US aid, and which economic sector the US aid affected; thirdly, it will trace the impact of US aid on Taiwan's foreign trade, and finally, to make a conclusion.

A Study for Fatigue Crack Propagation Behavior of KS50N Rail Steel under Welding Line (KS50N Rail 용접부의 피로균열 성장거동)

  • 박제용;지용찬;김진성;정경희
    • Proceedings of the KSR Conference
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    • 1998.11a
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    • pp.553-559
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    • 1998
  • This thesis studied to evaluate the fatigue behavior and propagation of rail steel under welding line. Test of crack growth was performed by all member of rail under constant amplitude loading at the structures laboratory in Hongik University. The effect of the following parameters with initiated crack length on the bottom edge of rail were studied. Here, fracture mechanics mode is opening mode. and Testing Material is KS50N Rail. From analysis and experimented result on the three Point bending in the lab, This paper presented a effect of crack growth , shape and remaining service life. Further more, according to the variable crack length, variable section and the ratio of section the fatigue behavior and propagation were studied.

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Effect of Synthetic Bile Acid Derivatives on the Cell Cycle Modulation of HT -29 Human Colon Cancer Cells

  • Park, Sang-Eun;Yee, Su-Bog;Choi , Hye-Joung;Chung, Sang-Woon;Park, Hwa-Sun;Yoo, Young-Hyun;Kim, Nam-Deuk
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.246.1-246.1
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    • 2002
  • We studied the effects of ursodeoxycholic acid (UDCA) and its synthetic derivatives. HS-l030 and HS-1183. and chenodeoxycholic acid (CDCA) and its synthetic derivatives, HS-1199 and HS-1200. on the human colon adenocarcinoma cell line. HT -29 (p53 mutant type). The effects on cell viability and growth were assessed by MTT assay and cell growth study. While UDCA and CDCA exhibited no significant effect, their novel derivatives inhibited the proliferation of HT-29 cell line in a concentration- and time-dependent manners. (omitted)

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Study on the Characteristics of Height Growth by PHV Age -Using longitudinal data of age 7 to 18- (PHV 연령별 신장 발육의 특징에 관한 연구 -7~18세의 종단적 자료를 이용하여-)

  • Park, Ju-Mi;Kim, Myung
    • Korean Journal of Health Education and Promotion
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    • v.8 no.2
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    • pp.74-86
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    • 1991
  • This study tried to clear the characteristics of height growth pattern depending on Peak Height Velocity age in early, average and late groups. And in it, height growth tendency of girl students in age 7 to 18 years old was compared and investigated in order to know influencing factors, menarcheal age relation. The samples were senior girl students at high school in Seoul. Longitudinal data and survey data were collected in August, 1990. The results could be summarized as follows: 1. On distance curve, the height growth line in early group tended to be the highest and in late group the lowest. On the other hand, on velocity curve late group showed the highest peak and early group showed the lowest peak. In late group, velocity curve was too steep. Of course, these early, average and late groups were classified by PHV age. 2. In these three groups, late group showed the most growth amount per year. However, on distance curve, early group showed higher line than late group. Perhaps this means that peak growth amount in late group might have an effect on mean. 3. Growth amount of adolescence spurt age in these three groups was 6.86cm at age 9(early group), 7.27cm at l1(average group) and 7.65cm at 13(late group). In early group, because. PHV age came too early, it was difficult to find exact adolescence spurt period. In early group, the adolescence spurt period is considered to come at about age 7 to 9. In average group, at 9 to 11 and at 12 to 13 in late group. Especially, spurt of late group was remarkable. 4. When the growth amount of PA, before PA and after PA was compared, growth amount of PA in all three groups was about 20%. In early group, growth amount of APV tended to be large and in late group, that of APV tended to be large and in late group, that of BPV was large. In average group, growth amount of BPV was larger than that of APV. 5. For the purpose of comparing total height growth amount of these groups at age 18, the height growth was assumed to be over. And then, the difference of three groups was studied but it's not significant. 6. Although the difference between height growth and family environment, dietary habits, exercise, disease history in these three groups was investigated, only the income was significant. The significance of all the other factors was not approved. 7. When menarcheal age was compared with PA, generally we know menarche appeared after 1∼2 years of PHV age. But in case of early group, the difference between PHV age and menarcheal age was 5.34 years. In average group, 2.45 years and 0.82 years in late group.

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The Growth Inhibitiory Effect of New Pyrrolo[1,2-${\alpha}$]benzimidazole Derivatives on Human Gastric Cancer Cells

  • Kim, Soo-Kie;Ahn, Chan-Mug;Choi, Sun-Ju;Park, Yoon-Sun;Cho, Hyung-Chul;Koh, Choon-Myung
    • Archives of Pharmacal Research
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    • v.20 no.5
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    • pp.410-413
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    • 1997
  • In the course of screening synthetic compounds to inhibit tumor cell growth, pyrrolo[1,2-.alpha.] benzimidazole (PBI), an intermediate of azamitosene, was found to inhibit a proliferation of gastric cancer cell lines. Despite a potential cytotoxic activity against solid tumor cells as opposed to that against rapidly-doubled leukemic cells, there has been no report on the inhibition of gastric cancer cell line by PBI and its' derivatives. The present experiment was designed to determine if PBI derivatives can effectively inhibit the cellular proliferation of gastric cancer cells by using in vitro as well as in vivo chemosensitivity system (MTT assay, clonogenic assay and human tumor xenografted assay). Of the tested PBI derivatives, PBI (18) and PBI (20), displayed the effective growth inhibition of cultured gastric cancer cells or even in the xenografted nude mouse model.

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Selective Antiproliferative and Apoptotic Effects of Quercetin in Normal Versus Tumorigenic Hepatic Cell Lines

  • Jeon, Young-Mi;Kim, Jong-Ghee;Lee, Jeong-Chae
    • Natural Product Sciences
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    • v.10 no.3
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    • pp.129-133
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    • 2004
  • Quercetin is a dietary anticancer chemical that is capable of inducing apoptosis in tumor cells. However, little is known about its biological effect in nonmalignant hepatic cells. Using embryonic normal hepatic cell line (BNL CL.2) and its SV40-transformed tumorigenic cell line (BNL SV A.8), we evaluated the effects of quercetin on cell proliferation and apoptosis. As the results, our present study demonstrated that quercetin had a selective growth inhibition in normal versus tumorigenic hepatic cells such that BNL SV A.8 cells were very sensitive to the quercetin-mediated cytotoxicity. In particular, as evidenced by the increased number of positively stained cells in the TUNEL assay, the induction of characteristic nuclear DNA ladders, and the migration of many cells to sub-G1 phase in the BNL SV A.8 cells, quercetin treatment more sensitively induced apoptosis in BNL SV A8 cells than in BNL CL.2 cells. Collectively, our findings suggest that quercetin can be approached as a potential agent that is capable of inducing selective growth inhibition and apoptosis of hepatic cancer cells.