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Spinal Cord Injury Treatment using a Noble Biocompatible Bridge

  • Hossain, S.M. Zakir;Babar, S.M. Enayetul;Azam, S.M. Golam;Sarma, Sailendra Nath;Haki, G.D.
    • Molecular & Cellular Toxicology
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    • v.3 no.3
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    • pp.151-158
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    • 2007
  • The failure of injured axons to regenerate in the mature central nervous system (CNS) has devastating consequences for victims of spinal cord injury (SCI). Traditional strategies to treat spinal cord injured people by using drug therapy and assisting devices that can not help them to recover fully various vital functions of the spinal cord. Many researches have been focused on accomplishing re-growth and reconnection of the severed axons in the injured region. Using cell transplantation to promote neural survival or growth has had modest success in allowing injured neurons to re-grow through the area of the lesion. Strategies for successful regeneration will require tissue engineering approach. In order to persuade sufficient axons to regenerate across the lesion to bring back substantial neurological function, it is necessary to construct an efficient biocompatible bridge (cell-free or implanted with different cell lines as hybrid implant) through the injured area over which axons can grow. Therefore, in this paper, spinal cord and its injury, different strategies to help regeneration of an injured spinal cord are reviewed. In addition, different aspects of designing a biocompatible bridge and its applications and challenges surrounding these issues are also addressed. This knowledge is very important for the development and optimalization of therapies to repair the injured spinal cord.

Wood Identification of the Veneer Species that grow in Korea - II. Wood Characteristics and Identification by the Microscopic Features - (한국산(韓國産) 단판수종의(單板樹種)의 목재식별(木材識別) - II. 현미경적(顯微鏡的) 성질(性質)에 의한 목재(木材)의 특성(特性) 및 그 식별(識別) -)

  • Lee, Phil-Woo;Eom, Young-Geun
    • Journal of the Korean Wood Science and Technology
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    • v.15 no.1
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    • pp.22-55
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    • 1987
  • This study was executed to offer the basic data needed to plywood industry in Korea for the future based on microscopic wood features as our previous paper reported by the macroscopic features. Microscopic wood characteristics for 50 species selected by the viewpoint of possible utility in future were examined and described by the species. Also, keys for the identification based on microscopic features were briefly prepared and presented by gymnosperm and angiospenn respectively.

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IPR Issues in World contents Industry - Japanese countermeasures and Its Lessons to Korea - (세계 컨텐츠산업의 지적재산권 문제 - 일본의 대책과 한국에의 시사점 -)

  • Chung, Su-Won
    • Journal of Arbitration Studies
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    • v.19 no.2
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    • pp.229-243
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    • 2009
  • The content industries environment has been undergoing significant changes due to rapid technological innovation and content market expansion. Interest in the industry is growing fast both in Asia and Europe. However, in Japan content industries are showing almost zero growth with no increase in overseas expansion. Until now, Japanese content industries have been able to grow based on domestic demands. Many different factors contributed to today's zero growth in Japanese content industries. Two main reasons are: 1) Their lack of interest in overseas expansion and 2) Insufficient investment in domestic human resources development. Considerable amounts of Japanese contents including films, music, games, and animations have been distributed in many Asian countries and today piracy problems in the region are at a serious level. According to 2004 records pirated editions accounted for 85%, 16%, 19%, and 36% in China, Korea, Hong Kong, and Taiwan respectively. Pirated editions bring economic losses to Japanese copyright profits. Making it worse, they weaken the motivation to create content and make it hard to activate cultural exchanges. Losses from copyright violations in Japanese content industries are expected to keep increasing in the future. In order to make Japan competitive and grow it is crucial to take proper measures to protect copyright infringements. This study considers the current situation of the Japanese content market, infringement issues in content which is causing many problems in Asian countries, including China, and facts about losses caused by this problem.

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An Experimental Study on the Comparison of the Establishment and Growth of Seedlings among Three Oak Species (참나무속 3종의 유식물 정착과 생장의 비교에 대한 실험적 연구)

  • Baek, Myeong-Su;Do-Soon Cho
    • The Korean Journal of Ecology
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    • v.19 no.2
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    • pp.125-139
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    • 1996
  • The relationships between environmental factors and the establishment and growth of oak seelings were studied in the greenhouse. The early seedling performances of three oak species (Quercus mongolica, Quercus serrata, Quercus variabilis) were compared. Mean seed weight was the biggest in Q. variabilis, and the smallest in Q. serrata, and the germination rate was higher in Q. variabilis than in Q. mongolica and Q. serrata. The germination rate was significantly affected by seed weight class in Q. serrata, but not in Q. mongolica. Emergence of oak seedlings was similar in all three oak species, and especially the first leaf emergence increased about twenty days after germination. An experiment was designed using three environmental factors (light, soil moisture, fertilizer) to compare the response of the three oak species. Light and soil moisture significantly affected the seedling height growth of Q. variabilis, but the effect was marginal in Q. mongolica and Q. serrata. However, growth of seedling biomass was significant in all three oak species. In contrast, fertilizer did not affect seedling growth of any of the oak species. Q. variabilis is expected to grow well in large gaps because it is very sensitive and responds well to high light and high moisture conditions. Q. mongolica and Q. serrata are relatively tolerant to shade but may need gaps for the seelings to grow into saplings.

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Characterization of Trichloroethylene and Phenol Degradation by Acinetobaeter sp. T5-7 (Acinetobacter sp. T5-7에 의한 Phenol과 Trichloroethylene 분해특성)

  • Hong, Sung-Yong;Lee, Suk-Hee;Lee, Jung-Hae;Ha, Ji-Hong
    • Microbiology and Biotechnology Letters
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    • v.23 no.3
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    • pp.255-262
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    • 1995
  • Intact cells of Acinetobacter sp. T5-7 completely degraded trichloroethylene (TCE) following growth with phenol. This strain could grow on at least eleven aromatic compounds, e.g., benzaldehyde, benzene, benzoate, benzylalochol, catechol, caffeic acid, 2.4-D, p-hydroxybenzoate, phenol, protocatechuate and salicylate, and did grow on alkane, such as octane. But except phenol, other aromatic compounds did not induced TCE degradation. Phenol biotransformation products, catechol was identified in the culture media. However, catechol-induced cells did not degrade TCE. So we assumed that phenol hydroxylase was responsible for the degradation of TCE. The isolate T5-7 showed growth in MM2 medium containing sodium lactate and catechol rather than phenol, but did not display phenol hydroxyalse activity, suggesting induction of enzyme synthesis by phenol. Phenol hydroxylase activity was independent of added NADH and flavin adenine dinucleotide but was dependent on NADPH addition. Degradation of phenol produced catechols which are then cleaved by meta-fission. We identified catechol-2.3-dioxygenase by active staining of polyacrylamide gel.

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A study on hand growth of Korean adolescent boys from 14 to 19 years (한국 남자 청소년(14~19세)의 손 치수 성장 경향에 관한 연구)

  • Kim, Hyunsook;Chun, Jongsuk
    • The Research Journal of the Costume Culture
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    • v.22 no.5
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    • pp.702-711
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    • 2014
  • This study was performed to investigate the hand size growth of Korean adolescents boys. Subjects were between 14 and 19 years (n=352). We collected the right hand size data of 19 measurements from each subject using 3D hand scanner. The total 26 hand measurements were analyzed including seven calculated measurements. Subjects were divided into three age groups (early, middle and late). Their hand size were compared. The results showed that all hand length measurements were significantly difference among age groups. Adolescent boys hands were sharply grown at age 16 years old. The hand dimensions of middle age group were compared with twenties men (n=215). There were significant differences between two groups. The middle age adolescents' hands were shorter and thicker than twenties men. Subjects were also divided by weight and height. Weight and height was closely related to hand size. The heavier and taller subjects had the thicker hand. Their fingers were longer than others. The adolescent boys and twenties men who were taller than the twenties' average height (173.4cm) were compared. Twenties men's hands were longer and thinner than that of adolescent boys. These results imply that the male adolescent hands grow short and thick in the adolescent period. Fingers continuously grow up as a long and thin shape after adolescent period.

Application of the Leak Before Break(LBB) Concept to a Heat Exchanger in a Nuclear Power Plant

  • Kwon, Jae-Do;Lee, Choon-Yeol;Lee, Yong-Son;Sul, Il-Chan
    • Journal of Mechanical Science and Technology
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    • v.15 no.1
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    • pp.10-20
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    • 2001
  • The leak before break(LBB) concept is difficult to apply to a structure with a thin tube that is immersed in a water environment. A heat exchanger in a nuclear power plant is such a structure. The present paper addresses an application of the LBB concept to a heat exchanger in a nuclear power plant. The minimum leaked coolant amount(approximately 37.9 liters) containing the radioactive material which can activate the radiation detector device installed in near the heat exchanger is assumed. A postulated initial flaw size that can not grow to a critical flaw size within the time period to activate the radiation detector is justified. In this case, the radiation detector can activate the warning signal caused by coolant leakage from initially postulated flaws of the heat exchanger. The nuclear plant can safely shutdown when this occurs. Since the postulated initial flaw size can not grow to the critical flaw size, the structural integrity of the heat exchanger is not impeded. Particularly the informational scenario presented in this paper discusses an actual nuclear plant.

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Bioconversion of Straw Into Improved Fodder: Mycoprotein Production and Cellulolytic Acivity of Rice Straw Decomposing Fungi

  • Helal, G.A.
    • Mycobiology
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    • v.33 no.2
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    • pp.90-96
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    • 2005
  • Sixty two out of the sixty four species of fungal isolates tested could produce both $exo-{\beta}1,4-gluconase\;(C_1)$ and $endo-{\beta}1,4-gluconase\;(C_x)$ on pure cellulose and rice straw as carbon source in Czapek's medium. Fifty-eight and fifteen species were able to grow at $25^{\circ}C$ and at $45^{\circ}C$, respectively. Eleven species could grow at both $25^{\circ}C$ and $45^{\circ}C$ while, four species appeared only at $45^{\circ}C$. The most cellulolytic species at $25^{\circ}C$ was Trichoderma koningii producing 1.164 $C_1$ (mg glucose/1 ml culture filtrate/1 hr) and 2.690 $C_x$ on pure cellulose, and 0.889 $C_1$, and 1.810 $C_x$ on rice straw, respectively. At $45^{\circ}C$, the most active thermotolerant species were Aspergillus terreus, followed by A. fumigatus. Talaromyces thermophilus was the highest active thermophilic species followed by Malbranchea sulfurea. Most of these species were also active in fermentation of rice straw at 25 and $45^{\circ}C$ (P<0.05). The most active ones were T. koningii, A. ochraceus and A. terreus, which produced 201.5, 193.1 and 188.1 mg crude protein/g dry straw, respectively.

Fungal Endophytes of Alnus incana ssp. rugosa and Alnus alnobetula ssp. crispa and Their Potential to Tolerate Heavy Metals and to Promote Plant Growth

  • Lalancette, Steve;Lerat, Sylvain;Roy, Sebastien;Beaulieu, Carole
    • Mycobiology
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    • v.47 no.4
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    • pp.415-429
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    • 2019
  • Soil contamination by metals is of particular interest, given that their retention times within the profile can be indefinite. Thus, phytostabilization can be viewed as a means of limiting metal toxicity in soils. Due to their ability to grow on contaminated soils, alders have repeatedly been used as key species in phytostabilization efforts. Alder ability to grow on contaminated sites stems, in part, from its association with microbial endophytes. This work emphasizes the fungal endophytes populations associated with Alnus incana ssp. rugosa and Alnus alnobetula ssp. crispa (previously A. viridis ssp. crispa) under a phytostabilization angle. Fungal endophytes were isolated from alder trees that were growing on or near disturbed environments; their tolerances to Cu, Ni, Zn, and As, and acidic pH (4.3, 3, and 2) were subsequently assessed. Cryptosporiopsis spp. and Rhizoscyphus spp. were identified as fungal endophytes of Alnus for the first time. When used as inoculants for alder, some isolates promoted plant growth, while others apparently presented antagonistic relationships with the host plant. This study reports the first step in finding the right fungal endophytic partners for two species of alder used in phytostabilization of metal-contaminated mining sites.

Studies on Development of Native Landscape Plants for Middle Area of Korea (중부지방 조경용 자생식물 소재의 개발에 관한 연구)

  • 방광자;이종석
    • Journal of the Korean Institute of Landscape Architecture
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    • v.21 no.1
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    • pp.63-82
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    • 1993
  • In the middle areas of South Korea, we collected 308 wild herbaceous species for studying the possibility of landscaping and, growing them at West in Yongin country of Kyunggi province. We observed their vegetative and flowering characteristic. And the result is as follow: 1. 76 species(24.7%) such as Hosta capitata, etc. of them are thought useful for flower-bedding or landscaping for park and ground-covering, while 94 species(30.6%) are regarded useful for ground-covering, potting and indoor-planting. They are Nepatica maxima and Thaliticum minus var. hypoleucum, etc. 46 species(15%) seems to be useful for flower-bedding, ground-covering and potting. 2. 264(85.7%) of all the observed species are for the enjoyment of their flowers, while 36 species(11.4%) for the enjoyment of their leaves, and 9 species(2.9%) for their fruit. They are Viburnum dilatatum, etc. 3. As for the relation of their habits to light conditions, 148 species(48%) grow int he full sun of more than 50,000Lux, 138 species(44.8%) usually in in the half shade of 20,000 to 30,000Lux, 15 species(4.9%) in the shade of some 10,000Lux, and 7 speciese grow either in the full sun or in the shde. 4. some species such as Wasabia koreansa, Allium succuliferum, Asterglehni, Ligulariafisheri, Ligularia stenocephala Epimedium koreanum are considered available as edible plants as well as ornamentals plants, and Houttuynia cordata. Saururus chinensis, Epimedium koreanum need to be further developed not only as ornamental plants but also medicinal plants.

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