• Title/Summary/Keyword: greater than 10 nodes

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Long-Term Survival of Women with Locally Advanced Breast Cancer with ≥10 Involved Lymph Nodes at Diagnosis

  • Zeichner, Simon Blechman;Cavalcante, Ludimila;Suciu, Gabriel Pius;Ruiz, Ana Lourdes;Hirzel, Alicia;Krill-Jackson, Elisa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3435-3441
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    • 2014
  • Background: Axillary lymph node status at diagnosis remains the strongest predictor of long-term survival in breast cancer. Patients with more than ten axillary lymph nodes at diagnosis have a poor long-term survival. In this single institutional study, we set out to evaluate the prognosis of this high-risk group in the era of multimodality therapy. Materials and Methods: In this retrospective study, we looked at all breast cancer patients with greater than ten axillary lymph nodes diagnosed at Mount Sinai Medical Center (MSMC) from January 1st 1990 to December 31st 2007 (n=161). In the univariate analysis, descriptive frequencies, median survival, and 5- and 10-year survival rates were estimated for common prognostic factors. A multivariate prognostic analysis for time-to-event data, using the extended Cox regression model was carried out. Results: With a median and mean follow-up of 70 and 89.9 months, respectively, the overall median survival was estimated to be 99 months. The five-year disease-free survival (DFS) was 59.3% and the ten-year DFS was 37.9%, whereas the five- and ten-year overall survival (OS) was 66.6% and 43.9%, respectively. Multivariate analysis revealed a significant improvement in DFS among black patients compared to whites (p=0.05), improved DFS and OS among young patients (ages 21-45) compared to elderly patients (age greater than 70) (p=0.00176, p=0.0034, respectively), and improved DFS and OS among patients whose tumors were ER positive (p=0.049, p=0.0034). Conclusions: In this single institution study of patients with greater than 10 positive axillary nodes, black patients had a significantly improved DFS compared with white patients. Young age and ER tumor positivity was associated with improved outcomes. Using multivariate analysis, there were no other variables associated with statistically significant improvements in DFS or OS including date of diagnosis. Further work is needed to improve breast cancer survival in this subgroup of patients.

Opportunity Coefficient for Cluster-Head Selection in LEACH Protocol

  • Soh, Ben;AlZain, Mohammed;Lozano-Claros, Diego;Adhikari, Basanta
    • International Journal of Computer Science & Network Security
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    • v.21 no.1
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    • pp.6-11
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    • 2021
  • Routing protocols play a pivotal role in the energy management and lifespan of any Wireless Sensor Network. Lower network lifetime has been one of the biggest concerns in LEACH protocol due to dead nodes. The LEACH protocol suffers from uneven energy distribution problem due to random selection of a cluster head. The cluster head has much greater responsibility compared to other non- cluster head nodes and consumes greater energy for its roles. This results in early dead nodes due to energy lost for the role of cluster- head. This study proposes an approach to balance the energy consumption of the LEACH protocol by using a semi-deterministic opportunity coefficient to select the cluster head. This is calculated in each node with the battery energy level and node ID. Ultimately, based on the opportunity cost, cluster head will be selected and broadcasted for which other nodes with higher opportunity cost will agree. It minimizes the chances of nodes with lower battery level being elected as cluster head. Our simulation experiments demonstrate that cluster heads chosen using our proposed algorithm perform better than those using the legacy LEACH protocol.

Simulation and Evaluation of Redistribution Algorithms In Fault-Tolerant Distributed System (결함허용 분산시스템의 재분배 알고리즘의 시뮬레이션과 평가)

  • 최병갑;이천희
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.31B no.8
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    • pp.1-10
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    • 1994
  • In this paper load redistribution algorithm to allow fault-tolerance by redistributing the workload of n failure nodes to the remaining good nodes in distributed systems are investigated. To evaluate the efficiency of the algorithms a simulation model of algorithms is developed using SLAM II simulation language. The job arrival rate service rate failure and repair rate of nodes and communication delay time due to load migraion are used as parameters. The result of the simulation shows that the job arrival rate failure and repair rate of nodes do not affected on the relative efficiency of algorithms. If the communication delay time is greater than average job processing time algorithm B is better. Otherwise algorithm C is superior to the others.

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Evaluation of the 7th AJCC TNM Staging System in Point of Lymph Node Classification

  • Kim, Sung-Hoo;Ha, Tae-Kyung;Kwon, Sung-Joon
    • Journal of Gastric Cancer
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    • v.11 no.2
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    • pp.94-100
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    • 2011
  • Purpose: The 7th AJCC tumor node metastasis (TNM) staging system modified the classification of the lymph node metastasis widely compared to the 6th edition. To evaluate the prognostic predictability of the new TNM staging system, we analyzed the survival rate of the gastric cancer patients assessed by the 7th staging system. Materials and Methods: Among 2,083 patients who underwent resection for gastric cancer at the department of surgery, Hanyang Medical Center from July 1992 to December 2009, This study retrospectively reviewed 5-year survival rate (5YSR) of 624 patients (TanyN3M0: 464 patients, TanyNanyM1: 160 patients) focusing on the number of metastatic lymph node and distant metastasis. We evaluated the applicability of the new staging system. Results: There were no significant differences in 5YSR between stage IIIC with more than 29 metastatic lymph nodes and stage IV (P=0.053). No significant differences were observed between stage IIIB with more than 28 metastatic lymph nodes and stage IV (P=0.093). Distinct survival differences were present between patients who were categorized as TanyN3M0 with 7 to 32 metastatic lymph nodes and stage IV. But patients with more than 33 metastatic lymph nodes did not show any significant differences compared to stage IV (P=0.055). Among patients with TanyN3M0, statistical significances were seen between patients with 7 to 30 metastatic lymph nodes and those with more than 31 metastatic lymph nodes. Conclusions: In the new staging system, modifications of N classification is mandatory to improve prognostic prediction. Further study involving a greater number of cases is required to demonstrate the most appropriate cutoffs for N classification.

Responses of Growth and Yield Characters on Planting Density in Determinate and Indeterminate Soybeans (재식밀도에 따른 유ㆍ무한 신육형 콩의 생육 및 수량형질 반응)

  • Kim, Hong-Sig;Hong, Eun-Hi;Park, Sang-Il;Park, Yeon-Kyu
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.38 no.2
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    • pp.189-195
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    • 1993
  • This study was conducted to obtain the .basic informations for developing soybean varieties and mechanizing cultivation at the Crop Experiment Station, Rural Development Administration, Suwon, Korea in 1990. Two determinate soybean varieties, Hwangkeurnkong and Jangyeobkong, and two indeterminate soybean varieties, Clark and Williams were planted at three planting densities (33,22,16 plants / $m^2$). Number of branches and number of nodes on branches per unit area ($m^2$) were greater in determinate varieties than in indeterminate ones, and number of nodes on mainstem were greater in indeterminate varieties than in determinate ones. The higher planting density increased those characters. Seed weight per unit area ($m^2$) was higher in determinate varieties than in indeterminate ones, and it was great at the higher planting density. Indeterminate varieties showed greater mainstem dependence rate for yield components than determinate ones did. Harvest index was higher in indeterminate varieties than in determinate ones. The lower planting density increased harvest index. Stem dry weight per unit area($m^2$) was greater in determinate varieties than in indeterminate ones, and it was greater at the higher planting density. Variations among plants were great in the order of branch-related yield characters > total plant-re-lated yield characters > mainstem-related yield characters > morphological characters of mainstem and 100 seed weight. Difference between determinate and indeterminate varieties was significant in branch-related characters. Indeterminate varieties showed greater variations than determinate ones did in branch-related yield characters at different planting densities.

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Effect of Vascular Bundles and Fiber Sheaths in Nodes and Internodes of Gigantochloa apus Bamboo Strips on Tensile Strength

  • Atmawi DARWIS;Anne HADIYANE;Endah SULISTYAWATI;Ihak SUMARDI
    • Journal of the Korean Wood Science and Technology
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    • v.51 no.4
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    • pp.309-319
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    • 2023
  • Bamboo culm is in the form of a tube/pipe, composed of internodes which are bounded by a partition/diaphragm (node). Anatomically, bamboo is composed of vascular bundles and parenchyma ground tissue. One of the constituents of vascular bundles is fibers that are grouped to form a fiber sheath. The anatomical structure of the nodes and internodes is thought to influence the strength of bamboo strips, including tensile strength. This study aimed to determine the characteristics of vascular bundles (distribution and fiber percentage) and their effects on the density and tensile strength of Gigantochloa apus bamboo strips with and without nodes. The bamboo culms were divided into three parts (outer, middle, and inner) along the radial direction. The results showed that the distribution of vascular bundles and percentage of fiber sheaths decreased significantly from the outer to the inner layer. This also had a significantly decreased density and tensile strength. Furthermore, the number of vascular bundles (in the transverse plane) was greater in the internodes than in the nodes. Anatomically, the orientation of the vascular bundles at irregular nodes is observed in the radial and tangential planes, where the direction is not only in the axial direction, but also in the radial and tangential directions. This caused the tensile strength of the G. apus bamboo strips to be lower at the nodes than at the internodes.

A CPLD Low Power Algorithm considering the Structure (구조를 고려한 CPLD 저전력 알고리즘)

  • Kim, Jae Jin
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.10 no.1
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    • pp.1-6
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    • 2014
  • In this paper, we propose a CPLD low power algorithm considering the structure. The proposed algorithm is implemented CPLD circuit FC(Feasible Cluster) for generating a problem occurs when the node being split to overcome the area and power consumption can reduce the algorithm. CPLD to configure and limitations of the LE is that the number of OR-terms. FC consists of an OR node is divided into mainly as a way to reduce the power consumption with the highest number of output nodes is divided into a top priority. The highest number of output nodes with the highest number of switching nodes become a cut-point. Division of the node is the number of OR-terms of the number of OR-terms LE is greater than adding the input and output of the inverter converts the AND. Reduce the level, power consumption and area. The proposed algorithm to MCNC logic circuits by applying a synthetic benchmark experimental results of 13% compared to the number of logical blocks decreased. 8% of the power consumption results in a reduced efficiency of the algorithm represented been demonstrated.

Improvement Transmission Reliability between Flight Type Air Node Using Concatenated Single Antenna Diversity (비행형 에어노드의 데이터 전송 신뢰성 향상을 위한 연접 단일 안테나 다이버시티 시스템)

  • Kang, Chul-Gyu;Kim, Dae-Hwan
    • Journal of Advanced Navigation Technology
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    • v.15 no.6
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    • pp.1053-1058
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    • 2011
  • In this paper, we propose a concatenated single antenna diversity system to assure the data transmission reliability between flight type air nodes which move according to their atypical orbit, then analyze its performance. The proposed system achieve a diversity gain using single antenna and a coding gain from convolutional code simultaneously. Simulation result about the bit error rate(BER) of the proposed system shows that its BER performance is about 9.5dB greater than convolutional code at $10^{-4}$ and about 14dB greater than space time block code at $10^{-3}$ which has a full diversity gain. In addition, compared with space time trellis code with diversity gain and coding gain, the proposed system shows the better 4dB at a BER of $10^{-5}$. Therefore, it is necessary that concatenated single antenna diversity should be adopted to the reliable data transmission of flight type air nodes.

A Study on Intrusion Detection Method using Collaborative Technique (협업 기법을 이용한 침입탐지 탐지 방법에 관한 연구)

  • Yang, Hwan Seok
    • Convergence Security Journal
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    • v.21 no.1
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    • pp.121-127
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    • 2021
  • MANET, which does not have any infrastructure other than wireless nodes, has the advantage of being able to construct a fast network. However, the movement of nodes and wireless media are also the causes of security vulnerabilities of MANET. In particular, the damage caused by the attacking nodes existing on the network is considerably greater than that of other networks. Therefore, it is necessary to detection technique for attacking nodes and techniques to reduce damage caused by attacks. In this paper, we proposed a hierarchical structure technique to increase the efficiency of intrusion detection and collaboration-based intrusion detection technique applying a P2P mesh network configuration technique to reduce damage caused by attacks. There was excluded the network participation of the attacking node in advance through the reliability evaluation of the nodes in the cluster. In addition, when an attack by an attacking node is detected, this paper was applied a method of minimizing the damage of the attacking node by transmitting quickly the attack node information to the global network through the P2P mesh network between cluster heads. The ns-2 simulator was used to evaluate the performance of the proposed technique, and the excellent performance of the proposed technique was confirmed through comparative experiments.

Performance Evaluation of a New AODV Protocol with Auxiliary Metrics

  • Ngo, Van-Vuong;Jang, Jaeshin
    • Journal of information and communication convergence engineering
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    • v.14 no.1
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    • pp.14-20
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    • 2016
  • The AODV protocol uses many RREQ messages and one RREP message in the path-discovery process. This protocol has only one metric, the number of hops. Although it is simple, this protocol is not efficient. To avoid this problem, we propose a new AODV with two auxiliary metrics (AuM-2-AODV). The AuM-2-AODV protocol tries multiple route replies, which reduces the chance of path failure and helps the network obtain a better data rate. It has two auxiliary metrics, the remaining energy of its nodes and the number of HELLO messages received at the nodes. With these two metrics, the reliable path from the source node to the destination node will be chosen. In this paper, the performance of the AuM-2-AODV is evaluated using the NS-3 simulator. The performance results show that AuM-2-AODV provides greater throughput and packet delivery ratio by 20% and up to 50% and about 100% in some cases, respectively, than previous protocols.