• 제목/요약/키워드: greater than 10 nodes

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Long-Term Survival of Women with Locally Advanced Breast Cancer with ≥10 Involved Lymph Nodes at Diagnosis

  • Zeichner, Simon Blechman;Cavalcante, Ludimila;Suciu, Gabriel Pius;Ruiz, Ana Lourdes;Hirzel, Alicia;Krill-Jackson, Elisa
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권8호
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    • pp.3435-3441
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    • 2014
  • Background: Axillary lymph node status at diagnosis remains the strongest predictor of long-term survival in breast cancer. Patients with more than ten axillary lymph nodes at diagnosis have a poor long-term survival. In this single institutional study, we set out to evaluate the prognosis of this high-risk group in the era of multimodality therapy. Materials and Methods: In this retrospective study, we looked at all breast cancer patients with greater than ten axillary lymph nodes diagnosed at Mount Sinai Medical Center (MSMC) from January 1st 1990 to December 31st 2007 (n=161). In the univariate analysis, descriptive frequencies, median survival, and 5- and 10-year survival rates were estimated for common prognostic factors. A multivariate prognostic analysis for time-to-event data, using the extended Cox regression model was carried out. Results: With a median and mean follow-up of 70 and 89.9 months, respectively, the overall median survival was estimated to be 99 months. The five-year disease-free survival (DFS) was 59.3% and the ten-year DFS was 37.9%, whereas the five- and ten-year overall survival (OS) was 66.6% and 43.9%, respectively. Multivariate analysis revealed a significant improvement in DFS among black patients compared to whites (p=0.05), improved DFS and OS among young patients (ages 21-45) compared to elderly patients (age greater than 70) (p=0.00176, p=0.0034, respectively), and improved DFS and OS among patients whose tumors were ER positive (p=0.049, p=0.0034). Conclusions: In this single institution study of patients with greater than 10 positive axillary nodes, black patients had a significantly improved DFS compared with white patients. Young age and ER tumor positivity was associated with improved outcomes. Using multivariate analysis, there were no other variables associated with statistically significant improvements in DFS or OS including date of diagnosis. Further work is needed to improve breast cancer survival in this subgroup of patients.

Opportunity Coefficient for Cluster-Head Selection in LEACH Protocol

  • Soh, Ben;AlZain, Mohammed;Lozano-Claros, Diego;Adhikari, Basanta
    • International Journal of Computer Science & Network Security
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    • 제21권1호
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    • pp.6-11
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    • 2021
  • Routing protocols play a pivotal role in the energy management and lifespan of any Wireless Sensor Network. Lower network lifetime has been one of the biggest concerns in LEACH protocol due to dead nodes. The LEACH protocol suffers from uneven energy distribution problem due to random selection of a cluster head. The cluster head has much greater responsibility compared to other non- cluster head nodes and consumes greater energy for its roles. This results in early dead nodes due to energy lost for the role of cluster- head. This study proposes an approach to balance the energy consumption of the LEACH protocol by using a semi-deterministic opportunity coefficient to select the cluster head. This is calculated in each node with the battery energy level and node ID. Ultimately, based on the opportunity cost, cluster head will be selected and broadcasted for which other nodes with higher opportunity cost will agree. It minimizes the chances of nodes with lower battery level being elected as cluster head. Our simulation experiments demonstrate that cluster heads chosen using our proposed algorithm perform better than those using the legacy LEACH protocol.

결함허용 분산시스템의 재분배 알고리즘의 시뮬레이션과 평가 (Simulation and Evaluation of Redistribution Algorithms In Fault-Tolerant Distributed System)

  • 최병갑;이천희
    • 전자공학회논문지B
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    • 제31B권8호
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    • pp.1-10
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    • 1994
  • In this paper load redistribution algorithm to allow fault-tolerance by redistributing the workload of n failure nodes to the remaining good nodes in distributed systems are investigated. To evaluate the efficiency of the algorithms a simulation model of algorithms is developed using SLAM II simulation language. The job arrival rate service rate failure and repair rate of nodes and communication delay time due to load migraion are used as parameters. The result of the simulation shows that the job arrival rate failure and repair rate of nodes do not affected on the relative efficiency of algorithms. If the communication delay time is greater than average job processing time algorithm B is better. Otherwise algorithm C is superior to the others.

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Evaluation of the 7th AJCC TNM Staging System in Point of Lymph Node Classification

  • Kim, Sung-Hoo;Ha, Tae-Kyung;Kwon, Sung-Joon
    • Journal of Gastric Cancer
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    • 제11권2호
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    • pp.94-100
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    • 2011
  • Purpose: The 7th AJCC tumor node metastasis (TNM) staging system modified the classification of the lymph node metastasis widely compared to the 6th edition. To evaluate the prognostic predictability of the new TNM staging system, we analyzed the survival rate of the gastric cancer patients assessed by the 7th staging system. Materials and Methods: Among 2,083 patients who underwent resection for gastric cancer at the department of surgery, Hanyang Medical Center from July 1992 to December 2009, This study retrospectively reviewed 5-year survival rate (5YSR) of 624 patients (TanyN3M0: 464 patients, TanyNanyM1: 160 patients) focusing on the number of metastatic lymph node and distant metastasis. We evaluated the applicability of the new staging system. Results: There were no significant differences in 5YSR between stage IIIC with more than 29 metastatic lymph nodes and stage IV (P=0.053). No significant differences were observed between stage IIIB with more than 28 metastatic lymph nodes and stage IV (P=0.093). Distinct survival differences were present between patients who were categorized as TanyN3M0 with 7 to 32 metastatic lymph nodes and stage IV. But patients with more than 33 metastatic lymph nodes did not show any significant differences compared to stage IV (P=0.055). Among patients with TanyN3M0, statistical significances were seen between patients with 7 to 30 metastatic lymph nodes and those with more than 31 metastatic lymph nodes. Conclusions: In the new staging system, modifications of N classification is mandatory to improve prognostic prediction. Further study involving a greater number of cases is required to demonstrate the most appropriate cutoffs for N classification.

재식밀도에 따른 유ㆍ무한 신육형 콩의 생육 및 수량형질 반응 (Responses of Growth and Yield Characters on Planting Density in Determinate and Indeterminate Soybeans)

  • 김홍식;홍은희;박상일;박연규
    • 한국작물학회지
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    • 제38권2호
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    • pp.189-195
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    • 1993
  • 본시험은 유ㆍ무한신육형콩의 생육 및 수량형질의 차이와 그 변이 정도를 구명하고 콩 육종 및 재배의 기초자료를 얻고자 1990년 수원 작물시험장에서 실시하였다. 유한신육형인 황금콩과 장엽콩, 무한신육형인 Clark와 Qilliams를 공시하여 재식밀도는 휴폭을 60cm로 동일하게 하고 주간을 10cm (밀도, 33개체/$m^2$), 15cm(표준, 22개체/$m^2$) 및 20cm(소식, 16개체/$m^2$)로 달리하여 생육 및 수량형질의 재식밀도 반응을 검토한바 그 주요결과를 요약하면 다음과 같다. 1. 단위면적당($m^2$) 분지수와 분지절수는 유한신육형이 무한신육형 보다, 단위면적당($m^2$) 주경절수는 무한신육형이 유한신육형 보다 많았으며 밀식일수록 증가하였다. 2. 단위면적당($m^2$) 입종은 유한신육형이 무한신육형보다 많았고, 밀식일수록 많았다. 3. 수량구성요소의 주경의존도는 밀식일수록 높아 졌는데 이러한 경향은 유한신육형 보다 무한신육형에서 더 컸다. 4. 입경비는 무한신육형이 유한신육형 보다 높았으며 소식일수록 증가하였고,면적경중은 유한신육형이 무한신육형 보다 많았으며 밀식일수록 증가하였다. 5. 개체간 변이 분석 수량형질 > 개체전체의 수량형질 > 주경의 수량 형질 > 주경의 형태적 형질 및 100입종의 순으로 컸으며 유ㆍ무한신종육형간에 뚜렷한 차이는 분지 관련 형질이었다. 6. 재식밀도 변화에 따른 개체간 변이의 변동이 큰 형질은 분지의 수량형질로서 무한신육형이 유한신육형에 비하여 변이폭이 컸다.

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Effect of Vascular Bundles and Fiber Sheaths in Nodes and Internodes of Gigantochloa apus Bamboo Strips on Tensile Strength

  • Atmawi DARWIS;Anne HADIYANE;Endah SULISTYAWATI;Ihak SUMARDI
    • Journal of the Korean Wood Science and Technology
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    • 제51권4호
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    • pp.309-319
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    • 2023
  • Bamboo culm is in the form of a tube/pipe, composed of internodes which are bounded by a partition/diaphragm (node). Anatomically, bamboo is composed of vascular bundles and parenchyma ground tissue. One of the constituents of vascular bundles is fibers that are grouped to form a fiber sheath. The anatomical structure of the nodes and internodes is thought to influence the strength of bamboo strips, including tensile strength. This study aimed to determine the characteristics of vascular bundles (distribution and fiber percentage) and their effects on the density and tensile strength of Gigantochloa apus bamboo strips with and without nodes. The bamboo culms were divided into three parts (outer, middle, and inner) along the radial direction. The results showed that the distribution of vascular bundles and percentage of fiber sheaths decreased significantly from the outer to the inner layer. This also had a significantly decreased density and tensile strength. Furthermore, the number of vascular bundles (in the transverse plane) was greater in the internodes than in the nodes. Anatomically, the orientation of the vascular bundles at irregular nodes is observed in the radial and tangential planes, where the direction is not only in the axial direction, but also in the radial and tangential directions. This caused the tensile strength of the G. apus bamboo strips to be lower at the nodes than at the internodes.

구조를 고려한 CPLD 저전력 알고리즘 (A CPLD Low Power Algorithm considering the Structure)

  • 김재진
    • 디지털산업정보학회논문지
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    • 제10권1호
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    • pp.1-6
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    • 2014
  • In this paper, we propose a CPLD low power algorithm considering the structure. The proposed algorithm is implemented CPLD circuit FC(Feasible Cluster) for generating a problem occurs when the node being split to overcome the area and power consumption can reduce the algorithm. CPLD to configure and limitations of the LE is that the number of OR-terms. FC consists of an OR node is divided into mainly as a way to reduce the power consumption with the highest number of output nodes is divided into a top priority. The highest number of output nodes with the highest number of switching nodes become a cut-point. Division of the node is the number of OR-terms of the number of OR-terms LE is greater than adding the input and output of the inverter converts the AND. Reduce the level, power consumption and area. The proposed algorithm to MCNC logic circuits by applying a synthetic benchmark experimental results of 13% compared to the number of logical blocks decreased. 8% of the power consumption results in a reduced efficiency of the algorithm represented been demonstrated.

비행형 에어노드의 데이터 전송 신뢰성 향상을 위한 연접 단일 안테나 다이버시티 시스템 (Improvement Transmission Reliability between Flight Type Air Node Using Concatenated Single Antenna Diversity)

  • 강철규;김대환
    • 한국항행학회논문지
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    • 제15권6호
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    • pp.1053-1058
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    • 2011
  • 본 논문에서는 비정형 궤도를 따라 이동하며 통신하는 비행체들 간의 데이터 전송 신뢰성을 보장하기 위해 컨볼루션 코드를 연접한 연접 단일 안테나 다이버시티 시스템을 제안하고 이 시스템의 성능을 분석하였다. 제안한 시스템은 단일 안테나를 사용하면서도 다이버시티 이득을 얻을 수 있고 컨볼루션 코드를 연접하였기 때문에 부호화 이득 또한 동시에 얻을 수 있다. 제안한 시스템의 비트 오율 성능(BER: bit error rate)을 시뮬레이션하여 컨볼루션 코드와 비교한 결과 BER $10^{-4}$에서 약 9.5dB 우수하였고, 최대 다이버시티 이득을 갖는 시공간 블록코드와 비교한 결과 BER $10^{-3}$에서 약 14dB 우수함을 확인 하였다. 마지막으로 부호화 이득과 다이버시티 이득을 동시에 갖는 시공간 트렐리스 코드와 그 성능을 비교하였을 때 $10^{-5}$의 BER에서 약 4dB 우수하였다. 따라서 비정형 궤도를 따라 이동하며 통신하는 비행형 에어노드간의 신뢰성 있는 통신을 위해서는 연접 단일 안테나 다이버시티 시스템의 적용이 필요하다.

협업 기법을 이용한 침입탐지 탐지 방법에 관한 연구 (A Study on Intrusion Detection Method using Collaborative Technique)

  • 양환석
    • 융합보안논문지
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    • 제21권1호
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    • pp.121-127
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    • 2021
  • 무선 노드 외에 어떠한 인프라도 존재하지 않는 MANET은 빠른 네트워크 구성할 수 있는 장점을 가지고 있다. 하지만 노드들의 이동, 무선 매체 등은 MANET이 가지고 있는 보안 취약점의 원인이기도 하다. 특히 네트워크상에 존재하는 공격 노드들에 의한 그 피해는 다른 네트워크에 비해 상당히 크다. 따라서 공격노드들에 대한 탐지 기법과 공격으로 인한 피해를 줄이는 기법도 반드시 필요하다. 본 논문에서는 침입탐지의 효율성을 높이기 위한 계층구조 기법과 공격으로 인한 피해를 줄이기 위해 P2P 메시 네트워크 구성 기법을 적용한 협업 기반 침입탐지 기법을 제안하였다. 제안한 기법에서는 클러스터내 노드들에 대한 신뢰도 평가를 통해 사전에 공격 노드에 대한 네트워크 참여를 배제하였다. 그리고 공격 노드에 의한 공격이 탐지되면 클러스터 헤드간의 P2P 메시 네트워크를 통해 네트워크 전역에 공격 노드 정보를 빠르게 전달함으로써 공격 노드의 피해를 최소화하는 방법을 적용하였다. 제안한 기법의 성능 평가를 위해 ns-2 시뮬레이터를 이용하였으며, 비교 실험을 통해 제안한 기법의 우수한 성능을 확인할 수 있었다.

Performance Evaluation of a New AODV Protocol with Auxiliary Metrics

  • Ngo, Van-Vuong;Jang, Jaeshin
    • Journal of information and communication convergence engineering
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    • 제14권1호
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    • pp.14-20
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    • 2016
  • The AODV protocol uses many RREQ messages and one RREP message in the path-discovery process. This protocol has only one metric, the number of hops. Although it is simple, this protocol is not efficient. To avoid this problem, we propose a new AODV with two auxiliary metrics (AuM-2-AODV). The AuM-2-AODV protocol tries multiple route replies, which reduces the chance of path failure and helps the network obtain a better data rate. It has two auxiliary metrics, the remaining energy of its nodes and the number of HELLO messages received at the nodes. With these two metrics, the reliable path from the source node to the destination node will be chosen. In this paper, the performance of the AuM-2-AODV is evaluated using the NS-3 simulator. The performance results show that AuM-2-AODV provides greater throughput and packet delivery ratio by 20% and up to 50% and about 100% in some cases, respectively, than previous protocols.